CD40 ligand (CD154) triggers a short-term CD4+ T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis

Journal of Experimental Medicine

Volumn 191, Issue 4, 2000, Pages 651-660

  Blair, Patrick J ^a,e   Riley, James L ^b   Harlan, David M ^a   Abe, Ryo ^c   Tadaki, Douglas K ^a   Hoffmann, Steven C ^a   White, Leonard ^a   Francomano, Tara ^a,d   Perfetto, Stephen J ^d   Kirk, Allan D ^a   June, Carl H ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE   (United States)

^e NAVAL MEDICAL RESEARCH CENTER   (United States)

Author keywords

Apoptosis; Costimulatory molecules; Cytokines; T lymphocytes; Transplantation

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GLYCOPROTEIN GP 39; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; PROTEIN BCL 2; PROTEIN BCL X; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; GRAFT SURVIVAL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOPHENOTYPING; LIGAND BINDING; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD; ANTIGENS, CD40; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN G; INTERFERON TYPE II; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMBRANE GLYCOPROTEINS; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034695882     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.4.651     Document Type: Article

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