Patterns of virus burden and T cell phenotype are established early and are correlated with the rate of disease progression in human immunodeficiency virus type 1-infected persons

Journal of Infectious Diseases

Volumn 173, Issue 4, 1996, Pages 877-887

  Wong, Michael T ^a   Dolan, Matthew J ^b   Kozlow, Eric ^b   Doe, Robert ^b   Melcher, Gregory P ^b   Burke, Donald S ^b   Neal Boswell, R ^b   Vahey, Maryanne ^b  

^a WILFORD HALL MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL ARTICLE; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; PRIORITY JOURNAL; T LYMPHOCYTE; VIREMIA;

ADULT; BASE SEQUENCE; CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; DNA PRIMERS; DNA, VIRAL; FEMALE; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HLA-DR ANTIGENS; HUMANS; HYPERSENSITIVITY, DELAYED; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; MALE; MILITARY MEDICINE; MOLECULAR SEQUENCE DATA; PROSPECTIVE STUDIES; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RNA, VIRAL; T-LYMPHOCYTE SUBSETS; TIME FACTORS;

EID: 0029887275     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.4.877     Document Type: Article

References (5)

1. Schnittman SM, Greenhouse JJ, Lane HC, Pierce PF, Fauci AS. Frequent detection of HIV-1-specific mRNAs in infected individuals suggests ongoing active viral expression in all stages of disease. Aids Res Hum Retroviruses 1991;7:361-7.
2. Piatak MJ, Saag MS, Yang LC, et al. High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science 1993;259:1749-54.
3. Michael NL, Vahey M, Burke DS, Redfield RR. Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: evidence for viral replication in all stages of HIV disease. J Virol 1992;66:310-6.
4. Bagnarelli P, Valenza A, Menzo S, et al. Dynamics of molecular parameters of human immunodeficiency virus type 1 activity in vivo. J Virol 1994;68:2495-502.
5. Pantaleo G, Graziosi C, Butini L, et al. Lymphoid organs function as major reservoirs for human immunodeficiency virus. Proc Natl Acad Sci USA 1991;88:9838-42.