A live-cell assay for studying extracellular and intracellular endothelin-converting enzyme activity

Hypertension

Volumn 30, Issue 4, 1997, Pages 837-844

  Parnot, Charles ^a   Le Moullec, Jean Michel ^a   Cousin, Marie Anne ^a   Guédin, Denis ^a   Corvol, Pierre ^b   Pinet, Florence ^b  

^a SANOFI   (France)

^b Centre de Recherche Interdisciplinaire en Biologie   (France)

Author keywords

Endothelin; Live cell assay; Metalloproteases; Promoter

Indexed keywords

COMPLEMENTARY DNA; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN CONVERTING ENZYME; ENZYME INHIBITOR; PHOSPHORAMIDON; THIORPHAN;

ANIMAL CELL; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL TONE; CELL MEMBRANE; CHO CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0030859485     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.30.4.837     Document Type: Article

References (37)

1. Kennedy R, Haynes W, Webb D. Endothelins as regulators of growth and function in endocrine tissues. Clin Endocrinol. 1993;39:259-265.
2. Masaki T, Yanagisawa M. Endothelins. Essays Biochem. 1992;7: 79-89.
3. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayishi Y, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent, vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
4. Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci U S A. 1989;86:2863-2867.
5. Seidah N, Day R, Marcinkiewicz M, Chretien M. Mammalian paired basic amino acid convertases of prohormones and proproteins. Ann N Y Acad Sci. 1993;680:135-146.
6. Opgenorth T, Wu-Wong J, Shiosaki K. Endothelin-converting enzymes. FASEB J. 1992;6:2653-2659.
7. Kashiwabara T, Inagaki Y, Ohta H, Iwamatsu A, Nomizu M, Nishikori K. Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect. FEBS Lett. 1989;247:73-76.
8. Kimura S, Kaysuya Y, Sawamura T, Shinmi O, Sugita Y, Yanagisawa M, Goto K, Masaki T. Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: structure-activity relationships of big endothelin-1. J Cardiovasc Pharmacol. 1989;13:S5-S7.
9. Ikegawa R, Matsumura Y, Tsukahara Y, Takaoka M, Morimoto S. Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme. Biochem Biophys Res Commun. 1990;171:669-675.
10. McMahon E, Palomo M, Moore W, McDonald J, Stern M. Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39- to endothelin-1-(1-21) in vitro. Proc Natl Acad Sci U S A. 1991;88:703-707.
11. Ahn K, Beningo K, Olds G, Hupe D. The endothelin-converting enzyme from human umbilical vein is a membrane-bound metalloprotease similar to that from bovine endothelial cells. Proc Natl Acad Sci U S A. 1992;89:8606-8610.
12. Okada K, Miyazaki Y, Takada J, Matsuyama K, Tamaki T, Yano M. Conversion of big endothelin-1 by membrane-bound metalloendopeptidase in cultured bovine endothelial cells. Biochem Biophys Res Commun. 1990;171:1192-1198.
13. Waxman L, Doshi KP, Gaul SL, Wang S, Bednar R, Stern A. Identification and characterization of endothelin converting activity from EAHY 926 cells: evidence for the physiologically relevant human enzyme. Arch Biochem Biophys. 1994;308:240-253.
14. Roques B, Noble F, Dauge V, Fournie-Zaluski M, Beaumont A. Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology. Pharmacol Rev. 1993;45:87-146.
15. Xu D, Emoto N, Giad A, Slaughter C, Kaw S, deWit D, Yanagisawa M. ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell. 1994;78:473-485.
16. Shimada K, Takahashi M, Tanzawa K. Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells. J Biol Chem. 1994;269:18275-18278.
17. Schmidt M, Kroger B, Jacob E, Seulberger H, Subkowski T, Ottep R, Meyer T, Schmalzing G, Hillen H. Molecular characterization of human and bovine ECE. FEBS Lett. 1994;356:238-243.
18. Shimada K, Takahashi M, Ikeda M, Tanzawa K. Identification and characterization of two isoforms of an endothelin-converting enzyme-1. FEBS Lett. 1995;371:140-144.
19. Yorimitsu K, Moroi K, Inagaki N, Saito T, Masuda Y, Masaki T, Semo S, Kimura S. Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2. Biochem Biophys Res Commun. 1995;208:721-727.
20. Valdenaire O, Rohrbacher E, Mattei MG. Organization of the gene encoding the human endothelin-converting enzyme (ECE-1). J Biol Chem. 1995;270:29794-29798.
21. Takahashi M, Fukuda K, Shimada K, Barnes K, Turner AJ, Ikeda M, Koike H, Yamamoto Y, Tanzawa K. Localization of rat endothelin-converting enzyme to vascular endothelial cells and some secretory cells. Biochem J. 1995;311:657-665.
22. Harrison V, Barnes K, Turner A, Wood E, Corder R, Vane J. Identification of endothelin-1 and big endothelin-1 in secretory vesicles isolated from bovine aortic endothelial cells. Proc Natl Acad Sci U S A. 1995;92:6344-6348.
23. Pribnow D, Muldoon LL, Fajardo M, Theodor L, Chen LYS, Magun BE. Endothelin induces transcription of fos/jun family genes: a prominent role for calcium ion. Mol Endocrinol. 1992;6:1003-1012.
24. Itoh Y, Yanagisawa M, Ohkubo S, Kimura C, Kosaka T, Inoue A, Ishida N, Mitsui Y, Onda H, Fujino M, Masaki M. Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin. FEBS Lett. 1988;231:440-444.
25. Ellis L, Clauser E, Morgan D, Edery M, Roth RA, Rutter WJ. Replacement of insulin receptor tyrosine kinase residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell. 1986;45:721-732.
26. Hosada K, Nakao K, Arai H, Suga S, Ogawa Y, Mukoyama M, Shirakami G, Saito Y, Nakanishi S, Imura H. Cloning and expression of human endothelin-1 receptor cDNA. FEBS Lett. 1991;287:23-26.
27. Angel P, Imagawa M, Chiu R, Stein B, Imbra R, Ramhsdorf H, Jonat C, Heulich P, Karin M. Phorbol ester-inducible genes contain a common cis-element recognized by a TPA-modulated transacting factor. Cell. 1987;49:729-739.
28. Ohlstein EH, Nambi P, Douglas SA, Edwards RM, Gellai M, Lago A, Leber JD, Cousins RD, Gao A, Frazee JS. SB209670, a rationally designed potent nonpetide endothelin receptor antagonist. Proc Natl Acad Sci U S A. 1994;91:8052-8056.
29. Graham F, VanDerEb A. A new technique for the assay of infectivity of human adenovirus DNA. Virology. 1975;52:456-476.
30. Aramori I, Nakanishi S. Coupling of two endothelin receptor subtypes to different signal transduction in transfected Chinese hamster ovary cells. J Biol Chem. 1992;267:12468-12474.
31. Sawamura T, Kasuya Y, Matsushita Y, Suzuki N, Shinmi O, Kishi N, Sugita Y, Yanagisawa M, Goto K, Masaki T, Kimura S. Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells. Biochem Biophys Res Commun. 1991;176:860-865.
32. Suzuki N, Matsumoto H, Kitada C, Kimura S, Miyauchi T, Fujino M. A sandwich-type enzyme immunoassay to detect immunoreactive big-endothelin-1 in plasma. J Immunol Methods. 1990;127:165-170.
33. Von Geldern TW, Holleman WH, Opgenorth TJ. A fluorogenic assay for endothelin-converting enzyme. Pept Res. 1991;4:32-35.
34. Takahashi M, Matsushita Y, Iijima Y, Tanzawa K. Purification and characterization of endothelin-converting enzyme from rat lung. J Biol Chem. 1993;268:21394-21398.
35. Hazan S, Fishov I, Zamai M, Caiolfa VR, Parola AH. Fluorescence polarization assay for endothelin-converting enzymes. Peptides. 1995;16:833-836.
36. Nishikori K, Akiyama H, Inagaki Y, Ohta H, Kashiwabara T, Iwamatsu A, Nomizu M, Morita A. Receptor binding affinity and biological activity of C-terminal elongated forms of endothelin-1. Neurochem Int. 1991;18:535-539.
37. Stratowa C, Himmler A, Czernilofsky AP. Use of luciferase reporter system for characterizing G-protein-linked receptors. Curr Opin Biotech. 1995;6:574-581.