Mapping the bimolecular interface of the parathyroid hormone (PTH)-PTH1 receptor complex: Spatial proximity between Lys27 (of the hormone principal binding domain) and Leu261 (of the first extracellular loop) of the human PTH1 receptor

Biochemistry

Volumn 39, Issue 28, 2000, Pages 8142-8152

  Greenberg, Zvi ^c   Bisello, Alessandro ^c   Mierke, Dale F ^a,c   Rosenblatt, Michael ^c   Chorev, Michael ^b,c  

^a BROWN UNIVERSITY   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c BOSTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BENZOPHENONE; LEUCINE; LYSINE; PARATHYROID HORMONE RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CROSS LINKING; ENZYME ACTIVATION; GENE EXPRESSION; GENE MAPPING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIPORTERS; CELLS, CULTURED; COS CELLS; CYANOGEN BROMIDE; DNA RESTRICTION ENZYMES; HUMANS; IODINE RADIOISOTOPES; LEUCINE; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PARATHYROID HORMONE; PHOTOAFFINITY LABELS; PROTEIN CONFORMATION; RECEPTORS, PARATHYROID HORMONE; REPRODUCIBILITY OF RESULTS; SACCHAROMYCES CEREVISIAE PROTEINS;

ANIMALIA;

EID: 0034682641     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000195n     Document Type: Article

References (65)

1. Fitzpatrick, L. A., and Bilezikian, J. P. (1996) in Principles of Bone Biology (Bilezikian, J. P., Raisz, L. G., Rodan, G. A., Eds.) pp 339-346, Academic Press, San Diego.
2. Segre, G. V. (1996) in Principles of Bone Biology (Bilezikian, J. P., Raisz, L. G., Rodan, G. A., Eds.) pp 377-403, Academic Press, San Diego.
3. Jüppner, H. (1994) Curr. Opin. Nephrol. Hypertens. 3, 371-378.
4. Serge, G. V., and Goldring, S. R. (1993) Trends Endocrinol. Metab. 4, 309-314.
5. Jüppner, H., Abou-Samra, A.-B., Freeman, M., Kong, X. F., Schipani, E., Richards, J., Kolakowski, L. F., Jr., Hock, J., Potts, J. T., Jr., Kronenberg, H. M., and Segre, G. V. (1991) Science 254, 1024-1026.
6. Pines, M., Fukayama, S., Costas, K., Meurer, E., Goldsmith, P. K., Xu, X., Muallem, S., Behar, V., Chorev, M., Rosenblatt, M., Tashjian, A. H., Jr., and Suva, L. J. (1996) Bone 18, 381-389.
7. Pines, M., Adams, A. E., Stueckle, S., Bessalle, R., Rashti-Behar, V., Chorev, M., Rosenblatt, M., and Suva, L. J. (1994) Endocrinology 135, 1713-1716.
8. Abou-Samra, A.-B., Jüppner, H., Force, T., Freeman, M. W., Kong, X.-F., Schipani, E., Urena, P., Richards, J., Bonventre, J. V., Potts, J. T., Jr., Kronenberg, H. M., and Segre, G. V. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 2732-2736.
9. Chorev, M., and Rosenblatt, M. (1994) in The Parathyroids (Bilezikian, J. P., Levine, M. A., and Marcus, R., Eds) pp 139-156, Raven Press, Ltd., New York.
10. Williams, K. P., and Shoelson, S. E. (1993) J. Biol. Chem. 268, 5361-5364.
11. Dorman, G., and Prestwich, G. D. (1994) Biochemistry 33, 5661-5673.
12. Kojro, E., Eich, P., Gimpl, G., and Fahrenholz, F. (1993) Biochemistry 32, 13537-13544.
13. Blanton, M. P., Li, Y. M., Stimson, E. R., Maggio, J. E., and Cohen, J. B. (1994) Mol. Pharmacol. 46, 1048-1055.
14. Keutmann, H. T., and Rubin, D. A. (1993) Endocrinology 132, 1305-1312.
15. Li, Y. M., Marnerakis, M., Stimson, E. R., and Maggio, J. E. (1995) J. Biol. Chem. 270, 1213-1220.
16. Boyd, N. D., Kage, R., Dumas, J. J., Krause, J. E., and Leeman, S. E. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 433-437.
17. Kage, R., Leeman, S. E., Krause, J. E., Costello, C. E., and Boyd, N. D. (1996) J. Biol. Chem. 271, 25797-25800.
18. Girault, S., Sagan, S., Bolbach, G., Lavielle, S., and Chassaing, G. (1996) Eur. J. Biochem. 240, 215-222.
19. McNicoll, N., Gagnon, J., Rondeau, J.-J., Ong, H., and De Lean, A. (1996) Biochemistry 35, 12950-12956.
20. Bisello, A., Adams, A., Mierke, D. F, Pellegrini, M., Rosenblatt, M., Suva, L., and Chorev, M. (1998) J. Biol. Chem. 273, 22498-22505.
21. Mannstadt, M., Luck, M., Gardella, T., and Jüppner, H. (1998) J. Biol. Chem. 273, 16890-16896.
22. Behar, V., Bisello, A., Rosenblatt, M., and Chorev, M. (1999) Endocrinology 140, 4251-4261.
23. Behar, V., Bisello, A., Rosenblatt, M., and Chorev, M. (2000) J Biol. Chem. 275, 9-17.
24. Adams, A. E., Bisello, A., Chorev, M., Rosenblatt, M., and Suva, L. J. (1998) Mol. Endocrinol. 12, 1673-1683.
25. Chorev, M., and Rosenblatt, M. (1996) in Principles of Bone Biology (Bilezikian, J. P., Raisz, L. G., Rodan, G. A., Eds.) pp 305-323, Academic Press, Inc., San Diego.
26. Zhou, A. T., Besalle, R., Bisello, A., Nakamoto, C., Rosenblatt, M., Suva, L. J., and Chorev, M. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 3644-3649.
27. Rolz, C., Pellgrini, M., and Mierke, D. F. (1999) Biochemistry 38, 6397-6405.
28. Rosenblatt, M., Segre, G. V., Tyler, G. A., Shepard, G. L., Nussbaum, S. R., and Potts, J. T., Jr. (1980) Endocrinology 107, 545-550.
29. Piserchio, A., Bisello, A., Rosenblatt, M., Chorev, M., and Mierke, D. F. (2000) Biochemistry 39, 8153-8160.
30. Merrifield, R. B. (1963) J. Am. Chem. Soc. 85, 2149-2154.
31. Nakamoto, C., Behar, V., Chin, K. R., Adams, A. E., Suva, L. J., Rosenblatt, M., and Chorev, M. (1995) Biochemistry 34, 10546-10552.
32. Goldman, M. E., Chorev, M., Reagan, J. E., Nutt, R. F., Levy, J. J., and Rosenblatt, M. (1988) Endocrinology 123, 1468-1475.
33. Roubini, E., Duong, L. T., Gibbons, S. W., Leu, C. T., Caulfield, M. P., Chorev, M., and Rosenblatt, M. (1992) Biochemistry 31, 4026-4033.
34. Solomon, Y., Londos, C., and Rodbell, M. A. (1974) Anal. Biochem. 58, 541-548.
35. Laemmli, U. K. (1970) Nature 227, 680-685.
36. Adams, A. E., Pines, M., Nakamoto, C., Behar, V., Yang, Q. M., Besalle, R., Chorev, M., Rosenblatt, M., Levine, M. A., and Suva, L. J. (1995) Biochemistry 34, 10553-10559.
37. Girault, S., Chassaing, G., Biais, J. C., Brunot, A., and Bolbach, G. (1996) Anal. Chem. 68, 2122-2126.
38. Phalipou, S., Seyer, R., Cotte, N., Breton, C., Barberis, C., Hibert, M., and Mouillac, B. (1999) J. Biol. Chem. 274, 23316-27.
39. Dong, M., Wang, Y., Pinon, D., Hadac, E., and Miller, L. (1999) J. Biol. Chem. 274, 903-909.
40. Servant, G., Laporte, S. A., Leduc, R., Escher, E., and Guillemette, G. (1999) J. Biol. Chem. 272, 8653-8659.
41. Hadac, E. M., Ji, Z., Pinon, D. I., Henne, R. M., Lybrand, T. P., and Miller, L. J. (1999) J. Med. Chem. 42, 2105-2111.
42. Kotzyba-Hibert, F., Grutter, T., and Goeldner, M. (1999) Mol. Neurobiol 20, 45-59.
43. Potts, J. T., Jr., Tregear, G. W., Keutmann, H. T., Niall, H. D., Sauer, R., Deftos, L. J., Dawson, B. F., Hogan, M. L., and Aurbach, G. D. (1971) Proc. Natl. Acad. Sci. U.S.A. 68, 63-67.
44. Tregear, G. W., van Rietschoten, J., Greene, E., Keutmann, H. T., Niall, H. D., Reit, B., Parsons, J. A., and Potts, J. T., Jr. (1973) Endocrinology 93, 1349-1353.
45. Rosenblatt, M., Callahan, E. N., Mahaffey, J. E., Pont, A., and Potts, J. T., Jr. (1977) J. Biol. Chem. 252, 5847-5851.
46. Horiuchi, N., Rosenblatt, M., Keutmann, H. T., Potts, J. T., Jr., and Holick, M. R. (1983) Am. J. Physiol. 244, E589-E595
47. Horiuchi, N., Holick, M. F., Potts, J. T., Jr., and Rosenblatt, M. (1983) Science 220, 1053-1055.
48. Nussbaum, S. R., Rosenblatt, M., and Potts, J. T., Jr., (1980) J. Biol. Chem. 255, 10183-10187.
49. Caulfield, M. P., McKee, R. L., Goldman, M. E., Duong, L. T., Fisher, J. E., Gay, C. T., DeHaven, P. A., Levy, J. J., Roubini, E., Nutt, R. F., Chorev, M., and Rosenblatt, M. (1990) Endocrinology 127, 83-87.
50. Gardella, T. J., Wilson, A. K., Keutmann, H. T., Oberstein, R., Potts, J. T., Jr., Kronenberg, H. M., and Nussbaum, S. R. (1993) Endocrinology 132, 2024-2030.
51. Gombert, F. O., Games, R., Feyen, J. H. M., and Cardinaux, F. (1996) in Peptides: Chemistry, Structure and Biology (Kaumaya, P. T. P., Hodges, R. S., Eds.) pp 661-662, Mayflower Scientific Ltd., England.
52. Barbier, J.-R., Neugebauer, W., Morley, P., Ross, V., Soska, M., Whitfield, J. F., and Willick, G. (1997) J. Med. Chem. 40, 1373-1380.
53. Neugebauer, W., Gagnon, L., Whitfield, J., and Willick, G. E. (1994) Int. J. Pept. Protein Res. 43, 555-562.
54. Surewicz, W. K., Neugebauer, W., Gagnon, L., MacLean, S., Whitfield, J. F., and Willick, G. (1994) in Peptides, Chemical Structures and Biology (Hodges, R. S., Smith, J. A., Eds) pp 556-558, ESCOM, Leiden.
55. Newman, W., Beall, L. D., Levine, M. A., Cone, J. L., Randhawa, Z. I., and Bertolini, D. R. (1989) J. Biol. Chem. 264, 16359-16366.
56. Abou-Samra, A.-B., Freeman, M., Jüppner, H., Uneno, S., and Segre, G. V. (1990) J. Biol. Chem. 265, 58-62.
57. Schipani, E., Karga, H., Karaplis, A. C., Potts, J. T., Jr., Kronenberg, H. M., Segre, G. V., Abou-Samra, A.-B., and Jüppner, H. (1993) Endocrinology 132, 2157-2165.
58. Olde, B., Sabirsh, A., and Owman, C. (1999) J. Mol. Neurosci. 11, 127-134.
59. Lee, C., Gardella, T. J., Abou-Samra, A.-B., Nussbaum, S. R., Segre, G. V., Potts, J. T., Jr., Kronenberg, H. M., and Jüppner, H. (1994) Endocrinology 135, 1488-1495.
60. Lee, C., Luck, M. D., Jüppner, H., Potts, J. T., Jr., Kronenberg, H. M., and Gardella, T. J. (1995) Mol. Endocrinol. 9, 1269-1278.
61. Bergwitz, C., Jusseaume, S. A., Luck, M. D., Jüppner, H., and Gardella, T. J. (1997) J. Biol. Chem. 272, 28861-28868.
62. Holtmann, M. H., Hadac, E. M., and Miller, L. J. (1995) J. Biol. Chem. 270, 14394-14398.
63. Holtmann, M. H., Ganguli, S., Hadac, E. M., Dolu, V., and Miller, L. J. (1999) J. Biol. Chem. 271, 14944-14949.
64. Hashimoto, H., Ogawa, N., Hagihara, N., Yamamoto, K., Imanishi, K., Nogi, H., Nishino, A., Fujita, T., Matsuda, T., Nagata, S., and Baba, A. (1997) Mol. Pharmacol. 52, 128-135.
65. Pellegrini, M., Royo, M., Rosenblatt, M., Chorev, M., and Mierke, D. F. (1998) J. Biol. Chem. 273, 1565-1585.