Pathogenic strategies of enteric bacteria

Nature

Volumn 406, Issue 6797, 2000, Pages 768-774

  Donnenberg, Michael S ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN FILAMENT; BACTERIAL VIRULENCE; CYTOSKELETON; ENTEROBACTERIACEAE; GRAM NEGATIVE INFECTION; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

BACTERIAL INFECTIONS; ENTEROBACTERIACEAE; HUMANS;

BACTERIA (MICROORGANISMS); ENTERIC BACTERIA; ENTEROBACTERIACEAE; NEGIBACTERIA;

EID: 0034680103     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35021212     Document Type: Review

References (54)

1. Whittam, T. S. in Escherichia coli and Salmonella: Cellular and Molecular Biology (ed. Neidhardt, F. C.) 2708-2720 (ASM Press, Washington, DC, 1996).
2. Lawrence, J. G. & Ochman, H. Molecular archaeology of the Escherichia coli genome. Proc. Natl. Acad. Sci. USA 95, 9413-9417 (1998).
3. Waldor, M. K. & Mekalanos, J. J. Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272, 1910-1914 (1996).
4. Karaolis, D. K., Somara, S., Maneval, D. R. Jr, Johnson, J. A. & Kaper, J. B. A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria. Nature 399, 375-379 (1999)
5. Perna, N. T. et al. Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 66, 3810-3817 (1998).
6. Thanassi, D. G., Saulino, E. T. & Hultgren, S. J. The chaperone/usher pathway: a major terminal branch of the general secretory pathway. Curr. Opin. Microbiol. 1, 221-231 (1998).
7. Yoshida, T., Kim, S. R. & Komano, T. Twelve pil genes are required for biogenesis of the R64 thin pilus. J. Bacteriol. 181, 2038-2043 (1999).
8. Anantha, R. P., Stone, K. D. & Donnenberg, M. S. Effects of bfp mutations on biogenesis of functional enteropathogenic Escherichia coli type IV pili. J. Bacteriol. 182, 2498-2506 (2000).
9. Hamburger, Z. A., Brown, M. S., Isberg, R. R. & Bjorkman, P. I. Crystal structure of invasin: a bacterial integrin-binding protein. Science 286, 291-255 (1999).
10. Luo, Y. et al. Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex. Nature 405, 1073-1077 (2000).
11. Russel, M. Macromolecular assembly and secretion across the bacterial cell envelope: type II protein secretion systems. J. Mol. Biol. 279, 485-499 (1998).
12. Marciano, D. K., Russel, M. & Simon, S. M. An aqueous channel for filamentous phage export. Science 284, 1516-1519 (1999).
13. Young, G. M., Schmiel, D. H. & Miller, V. L. A new pathway for the secretion of virulence factors by bacteria: the flagellar export apparatus functions as a protein-secretion system. Proc. Natl. Acad Sci. USA 96, 6456-6461 (1999).
14. Kubori, T. et al. Supramolecular structure of the Salmonella typhimurium type III protein secretion system. Science 280, 602-605 (1998).
15. Blocker, A. et al. The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes. J. Cell Biol. 147, 683-693 (1999).
16. Knutton, S. et al. A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells. EMBO J. 17, 2166-2176 (1998).
17. Tardy, F. et al. Yersinia enterocolitica type III secretion-translocation system: channel formation by secreted Yops. EMBO J. 18, 6793-6799 (1999).
18. Davis, B. M. et al. Convergence of the secretory pathways for cholera toxin and the filamentous phage, CTXφ. Science 288, 333-335 (2000).
19. Donnenberg, M. S., Kaper, J. B. & Finlay, B. B. Interactions between enteropathogenic Escherichia coli and host epithelial cells. Trends Microbiol. 5, 109-114 (1997).
20. Knutton, S., Shaw, R. K., Anantha, R. P., Donnenberg, M. S. & Zorgani, A. A. The type IV bundle-forming pilus of enteropathogenic Escherichia coli undergoes dramatic alterations in structure associated with bacterial adherence, aggregation and dispersal. Mol. Microbiol. 33, 499-509 (1999).
21. Anantha, R. P., Stone, K. D. & Donnenberg, M. S. The role of BfpF, a member of the PilT family of putative nucleotide-binding proteins, in type IV pilus biogenesis and in interactions between enteropathogenic Escherichia coli and host cells. Infect. Immun. 66, 122-131 (1998).
22. Bieber, D. et al. Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli. Science 280, 2114-2118 (1998).
23. Kenny, B. et al. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 91, 511-520 (1997).
24. Sanger, J. M., Chang, R., Ashton, F., Kaper, J. B. & Sanger, J. W. Novel form of actin-based motility transports bacteria on the surface of infected cells. Cell Motil. Cytoskeleton 34, 279-287 (1996).
25. Sansonetti, P. J., Tran, V. N. & Egile, C. Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri. Clin. Infect. Dis. 28, 466-175 (1999).
26. Ménard, R., Prévost, M. C., Gounon, P., Sansonetti, P. & Dehio, C. The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells. Proc. Natl Acad. Sci. USA 93, 1254-1258 (1996).
27. Cudmore, S., Cossart, P., Griffiths, G. & Way, M. Actin-based motility of vaccinia virus. Nature 378, 636-638 (1995).
28. Loisel, T. P., Boujeman, R., Pantaloni, D. & Carlier, M. F. Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature 401, 613-616 (1999).
29. Jensen, V. B., Harty, J. T. & Jones, B. D. Interactions of the invasive pathogens Salmonella typhimurium, Listeria monocytogenes and Shigella flexneri with M cells and murine Peyer's patches. Infect. Immun. 66, 3758-3766 (1998).
30. Sansonetti, P. J., Arondel, J., Cavaillon, J.-M. & Huerre, M. Role of interleukin-1 in the pathogenesis of experimental shigellosis. J. Clin. Invest. 96, 884-892 (1995).
31. Achtman, M. et al. Yersinia pestis, the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis. Proc. Natl Acad. Sci. USA 96, 14043-14048 (1999).
32. Cornelis, G. R. & Wolf-Watz, H. The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells. Mol. Microbiol. 23, 861-867 (1997).
33. Monack, D. M., Mecsas, J., Bouley, D. & Falkow, S. Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice. J. Exp. Med. 188, 2127-2137 (1998).
34. Mirold, S. et al. Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain. Proc. Natl Acad. Sci. USA 96, 9845-9850 (1999).
35. Fu, Y. X. & Galán, J. E. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. Nature 401, 293-297 (1999).
36. Hersh, D. et al. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc. Natl Acad. Sci. USA 96, 2396-2401 (1999).
37. Hensel, M. et al. Simultaneous identification of bacterial virulence genes by negative selection. Science 269, 400-403 (1995).
38. Vazquez-Torres, A. et al. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science 287, 1655-1658 (2000).
39. Uchiya, K. et al. A Salmonella virulence protein that inhibits cellular trafficking. EMBO J. 18, 3924-3933 (1999).
40. Kalman, D. et al. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nature Cell Biol. 1, 389-391 (1999).
41. Ben-Ami, G. et al. Agents that inhibit Rho, Rac, and Cdc42 do not block formation of actin pedestals in HeLa cells infected with enteropathogenic Escherichia coli. Infect. Immun. 66, 1755-1758 (1998).
42. Egile, C. et al. Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility. J. Cell Biol. 146, 1319-1332 (1999).
43. Van Nhieu, G. T., Caron, E., Hall, A. & Sansonelti, P. J. IpaC induces actin polymerization and filopodia formation during Shigella entry epithelial cells. EMBO J. 18, 3249-3262 (1999).
44. Tran Van Nhieu, G., Ben-Ze'ev, A. & Sansonetti, P. J. Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin. EMBO J. 16, 2717-2729 (1997).
45. Bourdet-Sicard, R. et al. Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization. EMBO J. 18, 5853-5862 (1999).
46. Zhou, D. G., Mooseker, M. S. & Galán, J. E. An invasion-associated Salmonella protein modulates the actin-bundling activity of plastin. Proc. Natl Acad. Sci. USA 96, 10176-10181 (1999).
47. Hayward, R. D. & Koronakis, V. Direct nucleation and bundling of actin by the SipC protein of invasive Salmonella. EMBO J. 18, 4926-4934 (1999).
48. Hardt, W. D., Chen, L. M., Schuebel, K. E., Bustelo, X. R. & Galán, J. E. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells. Cell 93, 815-826 (1998).
49. Palmer, L. E., Hobbie, S., Galán, J. E. & Bliska, J. B. YopI of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-α production and downregulation of the MAP kinases p38 and JNK. Mol. Microbiol. 27, 953-965 (1998).
50. Schesser, K. et al. The yopI locus is required for Yersinia-mediated inhibition of NF-κB activation and cytokine expression: YopI contains a eukaryolic SH2-like domain that is essential for its repressive activity. Mol. Microbiol. 28, 1067-1079 (1998).
51. Persson, C. et al. Localization of the Yersinia PTPase to focal complexes is an important virulence mechanism. Mol. Microbiol. 33, 828-838 (1999).
52. Gas as a substrate Yersinia YopH (Yop54), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions. EMBO J. 16, 2730-2744 (1997).
53. Gas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions. EMBO J. 16, 2307-2318 (1997).
54. Zumbihl, R. et al. The cytotoxin YopT of Yersinia enterocolitica induces modification and cellular redistribution of the small GTP-binding protein RhoA. J. Biol. Chem. 274, 29289-29293 (1999).