Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: The development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 8, 2000, Pages 707-710

  Hsin, Ling Wei ^a   Webster, Elizabeth L ^b   Chrousos, George P ^c   Gold, Philip W ^b   Eckelman, William C ^d   Contoreggi, Carlo ^e   Rice, Kenner C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTALARMIN; CORTICOTROPIN RELEASING FACTOR RECEPTOR; FLUORO 4 (DIALKYLAMINO)PYRROLO[2,3 D]PYRIMIDINE; PYRIMIDINE DERIVATIVE; TRACER; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CEREBELLUM; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CEREBELLUM; CONTRAST MEDIA; FLUORINE; PYRIMIDINES; PYRROLES; RADIOLIGAND ASSAY; RATS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; TOMOGRAPHY, EMISSION-COMPUTED;

ANIMALIA;

EID: 0034678661     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00071-8     Document Type: Article

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