How lysophosphatidylcholine inhibits cell-cell fusion mediated by the envelope glycoprotein of human immunodeficiency virus

Virology

Volumn 235, Issue 2, 1997, Pages 201-208

  Günther Ausborn, Susanne ^a   Stegmann, Toon ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOPHOSPHATIDYLCHOLINE; VIRUS ENVELOPE PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL FUSION; CONTROLLED STUDY; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PRIORITY JOURNAL; VIRUS CELL INTERACTION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0242316982     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8699     Document Type: Article

References (53)

1. Allan J. S. Receptor-mediated activation of immunodeficiency viruses in viral fusion. Science. 252:1991;1322.
2. Bebbington C. R., Hentschel C. C. G. The use of vectors based on gene amplification for the expression of cloned genes in mammalian cells. DNA Cloning. 1987;IRL Press, Oxford.
3. J. Bentz, 1993, Viral fusion mechanisms, CRC Press, Boca Raton, FL.
4. Bestermann J. M., Domanico P. L. Association and metabolism of exogenously-derived lysophosphatidylcholine by cultured mammalian cells: Kinetics and mechanisms. Biochemistry. 31:1992;2046-2056.
5. Bosch M. L., Earl P. L., Fargnoli K., Picciafuoco S., Giombini F., Wong-Staal F., Franchini G. Identification of the fusion peptide of primate immunodeficiency viruses. Science. 244:1989;694-697.
6. 2. Biochim. Biophys. Acta. 1168:1993;13-22.
7. Chernomordik L. V., Chanturiya A., Green J., Zimmerberg J. The hemifusion intermediate and its conversion to complete fusion: Regulation by membrane composition. Biophys. J. 69:1995a;922-929.
8. Chernomordik L. V., Kozlov M. M., Melikyan G. B., Abidor I. G., Markin V. S., Chizmadzhev Y. A. The shape of lipid molecules and monolayer membrane fusion. Biochim. Biophys. Acta. 812:1985;643-655.
9. Chernomordik L. V., Kozlov M. M., Zimmerberg J. Lipids in biological membrane fusion. J. Membr. Biol. 146:1995b;1-14.
10. Chernomordik L. V., Leikina E. A., Cho M.-S., Zimmerberg J. Control of baculovirus gp64-induced syncytium formation by membrane lipid composition. J. Virol. 69:1995c;3049-3058.
11. 2+. FEBS Lett. 318:1993;71-76.
12. Chernomordik L. V., Zimmerberg J. Bending membranes to the task: Structural intermediates in bilayer fusion. Curr. Opin. Struct. Biol. 5:1995;541-547.
13. Colotto A., Martin I., Ruysschaert J.-M., Sen A., Hui S. W., Epand R. M. Structural study of the interaction between the SIV fusion peptide and model membranes. Biochemistry. 35:1996;980-999.
14. De Kruijff B., Van den Besselaar A. M. H. P., Van Deenen L. L. M. Outside-inside distribution and translocation of lysophosphatidylcholine vesicles as determined by 13C-NMR using (N-13CH3)-enriched lipids. Biochim. Biophys. Acta. 465:1977;443-453.
15. Doxsey S., Sambrook J., Helenius A., White J. An efficient method for introducing macromolecules into living cells. J. Cell Biol. 101:1985;19-27.
16. Ellens H., Bentz J., Mason D., Zhang F., White J. Fusion of influenza hemagglutinin-expressing fibroblasts with glycophorin-bearing liposomes: Role of hemagglutinin surface density. Biochemistry. 29:1990;9697-9707.
17. Felser J. M., Klimkait T., Silver J. A syncytic assay for human immunodeficiency virus envelope protein and its use in studying HIV-1 mutations. Virology. 170:1989;566-570.
18. Folch J., Lees M., Sloane-Stanley G. H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:1957;497-509.
19. Freed E. O., Martin M. A. The role of human immunodeficiency virus type 1 envelope glycoprotein in virus infection. J. Biol. Chem. 270:1995;23883-23886.
20. Freed E. O., Myers D. J., Risser. Identification and characterization of fusion and processing domains of HIV-2 glycoprotein. J. Virol. 66:1992;5472-5478.
21. Freed E. O., Myers D. J., Risser R. Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp 41. Proc. Natl. Acad. Sci. USA. 87:1990;4650-4654.
22. Frey S., Marsh M., Günther S., Pelchen-Matthews A., Stephens P., Ortlepp S., Stegmann T. Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency Virus-1. J. Virol. 69:1995;1462-1472.
23. Gallaher W. R. Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus. Cell. 50:1987;327-328.
24. Günther-Ausborn S., Praetor A., Stegmann T. Inhibition of influenza-induced membrane fusion by lysophosphatidylcholine. J. Biol. Chem. 270:1995;29279-29285.
25. Hughson F. M. Structural characterization of viral fusion proteins. Curr. Biology. 5:1995;265-274.
26. Kok J. W., ter Beest M., Scherphof G., Hoekstra D. A non-exchangeable fluorescent phospholipid analog as a membrane traffic marker of the endocytic pathway. Eur. J. Cell Biol. 53:1990;173-184.
27. Kowalski M., Potz J., Basiripour L., Dorfman T., Goh W. C., Terwilliger E., Dayton A., Rosen C., Haseltine W., Sodroski J. Functional regions of the envelope glycoprotein of human immunodeficiency virus type I. Science. 237:1987;1351-1355.
28. Kumar V. V. Complementary molecular shapes and additivity of the packing parameter of lipids. Proc. Natl. Acad. Sci. USA. 88:1991;444-448.
29. Lapham C. K., Ouyang J., Chandrasekhar B., Nguyen N. Y., Dimitrov D. S., Golding H. Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. Science. 274:1996;602-605.
30. Larsen C., Ellens H., Bentz J. Membrane fusion induced by the HIV env glycoprotein. Aloia R. C., Curtain C. C., Gordon L. L. Advances in Membrane Fluidity. 1992;143-156 Wiley-Liss, New York.
31. Martin I., Dubois M.-C., Saermark T., Epand R. M., Ruysschaert J. M. Lysophosphatidylcholine mediates the mode of insertion of the NH2-terminal SIV fusion peptide into the lipid bilayer. FEBS Lett. 333:1993;325-330.
32. Martin I., Ruysschaert J. M. Lysophosphatidylcholine inhibits vesicles fusion induced by the NH2-terminal extremity of SIV/HIV fusogenic proteins. Biochim. Biophys. Acta. 1240:1995;95-100.
33. Martin I., Schaal H., Scheid A., Ruysschaert J. M. Lipid membrane fusion induced by the human immunodeficieny virus type 1 gp41 N-terminal extremity is determined by its orientation in the lipid bilayer. J. Virol. 70:1996;298-304.
34. Moore J. P., Jameson B. A., Weiss R. A., Sattentau Q. J. The HIV-cell fusion reaction. Bentz J. Viral Fusion Mechanisms. 1993;233-289 CRC Press, Boca Raton.
35. Moore J. P., McKeating J. A., Weiss R., Clapham P. R., Sattentau Q. Receptor-mediated activation of immunodeficiency viruses in viral fusion. Science. 252:1991;1322-1323.
36. Pelchen-Matthews A., Clapham P., Marsh M. Role of CD4 endocytosis in human immunodeficiency virus infection. J. Virol. 69:1995;8164-8168.
37. Romero G., Thompson K., Biltonen R. L. The activation of porcine pancreas phospholipase A2 by dipalmitoylphosphatidylcholine large unilamellar vesicles. J. Biol. Chem. 262:1987;13476-13482.
38. Sattentau Q., Zolla-Pazner S., Poignard P. Epitope exposure on functional, oligomeric HIV-1 gp41 molecules. Virology. 206:1995;713-717.
39. Shangguan T., Alford D., Bentz J. Influenza-virus lipid mixing is leaky and largely insensitive to the material properties of the target membrane. Biochemistry. 35:1996;4956-4965.
40. Siegel D. P. Energetics of intermediates in membrane fusion: Comparison of stalk and inverted micellar intermediate mechanisms. Biophys. J. 65:1993a;2124-2140.
41. Siegel D. P. Modeling protein-induced fusion: Insights from the relative stability of lipidic structures. Bentz J. Viral Fusion Mechanisms. 1993b;475-512 CRC Press, Boca Raton.
42. Steffy K. R., Kraus G., Looney D. J., Wong-Staal F. Role of the fusogenic peptide sequence in syncytium formation and infectivity of human immunodeficiency type 2 virus. J. Virol. 66:1992;4532-4535.
43. Stegmann T., Delfino J. M., Richards F. M., Helenius A. The HA2 subunit of influenza hemagglutinin inserts into the target membrane prior to fusion. J. Biol. Chem. 266:1991;18404-18410.
44. Stegmann T., Doms R. W., Helenius A. Protein-mediated membrane fusion. Annu. Rev. Biophys. Biophys. Chem. 18:1989;187-211.
45. Stephens P. E., Cockett M. I. The construction of a highly efficient and versatile set of mammalian expression vectors. Nucleic Acids Res. 17:1989;7110.
46. Trkola A., Dragic T., Arthos J., Binley J. M., Olson W. C., Allaway G. P., Cheng-Mayer C., Roinson J., Maddon P. J., Moore J. P. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature (London). 384:1996;184-187.
47. Tsurudome M., Glück R., Graf R., Falchetto R., Schaller U., Brunner J. Mechanism of influenza induced-membrane fusion: Membrane insertion of the "fusion peptide" of hemagglutinin. J. Biol. Chem. 267:1992;20225-20232.
48. Vogel S. S., Leikina E. A., Chernomordik L. V. Lysophosphatidylcholine reversibly arrests exocytosis and viral fusion at a stage between triggering and membrane merger. J. Biol. Chem. 268:1993;25764-25768.
49. Weltzien H. U. Cytolytic and membrane-perturbing properties of lysophospatidylcholine. Biochim. Biophys. Acta. 559:1979;259-287.
50. White J., Matlin K., Helenius A. Cell fusion by Semliki Forest, influenza and vesicular stomatitis viruses. J. Cell Biol. 89:1981;674-679.
51. Wilschut J., Hoekstra D. Membrane fusion: Lipid vesicles as a model system. Chem. Phys. Lipids. 40:1986;145-166.
52. Wu L., Gerard N. P., Wyatt R., Choe H., Parolin C., Rufing N., Borsetti A., Cardoso A. A., Desjadin E., Newman W., Gerard C., Sodroski J. CD4-induced interaction of primary HIV-1 glycoproteins with the chemokine receptor CCR-5. Nature (London). 384:1996;179-183.
53. Yeagle P. L., Smith F. T., Young J. E., Flanagan T. D. Inhibition of membrane fusion by lysophosphatidylcholine. Biochemistry. 33:1994;1820-1827.