Use of large-scale expression cloning screens in the Xenopus laevis tadpole to identify gene function

Developmental Biology

Volumn 228, Issue 2, 2000, Pages 197-210

  Grammer, Timothy C ^a   Liu, Karen J ^a   Mariani, Francesca V ^a   Harland, Richard M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Development; Expression cloning; Gene function; Mesoderm; Neural; Pigmentation; Xenopus

Indexed keywords

COMPLEMENTARY DNA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA LIBRARY; EMBRYO; EMBRYO DEVELOPMENT; GENE FUNCTION; GENE ISOLATION; MESODERM; NONHUMAN; PIGMENTATION; PRIORITY JOURNAL; TISSUE SPECIFICITY; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 0034672039     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9945     Document Type: Article

References (70)

1. Ionizing radiation induces apoptosis and elevates cyclin A1-Cdk2 activity before but not after the midblastula transition in Xenopus
2. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure
3. Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development
4. A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
5. Anterior neurectoderm is progressively induced during gastrulation: The role of the Xenopus homeobox gene orthodenticle
6. XFKH2, a Xenopus HNF-3α homologue, exhibits both activin-inducible and autonomous phases of expression in early embryos
7. Synergism between Pax-8 and lim-1 in embryonic kidney development
8. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis
9. Activation of the transcription factor Glil and the Sonic hedgehog signalling pathway in skin tumours
10. Fate map for the 32-cell stage of Xenopus laevis
11. Inhibitory patterning of the anterior neural plate in Xenopus by homeodomain factors Dlx3 and Msx1
12. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
13. Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus
14. Formation and function of Spemann's organizer
15. Neural induction in Xenopus
16. A developmental timer that regulates apoptosis at the onset of gastrulation
17. MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos
18. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
19. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor
20. Molecular characterization of the type 2 phosphatidic acid phosphatase
21. Expression cloning in the test tube
22. Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm
23. Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
24. Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation
25. Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration
26. The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer
27. Expression cloning of siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis
28. A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
29. Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation
30. Small pool expression screening: Identification of genes involved in cell cycle control, apoptosis, and early development
31. The tetraspanin superfamily: Molecular facilitators
32. XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue
33. Reduced expression of the metastasis suppressor gene KAI1 in advanced colon cancer and its metastases
34. Induction of the prospective neural crest of Xenopus
35. Sib selection
36. Geminin, an inhibitor of DNA replication, is degraded in mitosis
37. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis
38. Cloning of mix-related homeodomain proteins using fast retrieval of gel shift activities (FROGS), a technique for the isolation of DNA-binding proteins
39. Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction
40. Fates of the blastomeres of the 32-cell-stage Xenopus embryo
41. Conserved segmental expression of Krox-20 in the vertebrate hindbrain and its relationship to lineage restriction
42. The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions
43. A developmentally regulated, nervous system-specific gene in Xenopus encodes a putative RNA-binding protein
44. TLS-CHOP and the role of RNA-binding proteins in oncogenic transformation
45. Sizzled: A secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos
46. A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction
47. Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center
48. Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos
49. A nodal-related gene defines a physical and functional domain within the Spemann organizer
50. Injected Wnt RNA induces a complete body axis in Zenopus embryos
51. Developmentally regulated activation of apoptosis early in Xenopus gastrulation results in cyclin A degradation during interphase of the cell cycle
52. Properties of the caspases
53. Systematic identification of mitotic phosphoproteins
54. Mesoderm induction by BMP-4 and -7 heterodimers
55. A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo
56. Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4
57. XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development
58. Expression of achaetescute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
59. Developmental patterning genes and their conserved functions: From model organisms to humans
60. FGF-mediated mesoderm induction involves the Src-family kinase Laloo
61. Frequent down-regulation of the KAI1(CD82) metastasis suppressor protein in human cancer cell lines
62. Cytoskeletal interactions of Rap1b in platelets
63. Involvement of p21ras in Xenopus mesoderm induction
64. Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development
65. The early expression control of Xepsin by nonaxial and planar posteriorizing signals in Xenopus epidermis
66. Prostate cancer metastasis-suppressor genes: A current perspective
67. Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1
68. Expression of GATA-binding proteins during embryonic development in Xenopus laevis