FcγRIIA requires a Gi-dependent pathway for an efficient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation

Blood

Volumn 96, Issue 10, 2000, Pages 3439-3446

  Gratacap, M P ^a   Herault, J P ^a   Viala, C ^a   Ragab, A ^a   Savi, P ^a   Herbert, J M ^a   Chap, H ^a   Plantavid, M ^a   Payrastre, B ^a  

^a CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; ALPHA 2A ADRENERGIC RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; SCAVENGER; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANTICOAGULANT AGENT; FC GAMMA RECEPTOR IIA; FC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HEPARIN; ISOENZYME; LEUKOCYTE ANTIGEN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; PHOSPHOLIPASE C GAMMA; POLYPHOSPHOINOSITIDE; PURINE P2 RECEPTOR; TYROSINE;

ARTICLE; CALCIUM MOBILIZATION; CROSS LINKING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SECOND MESSENGER; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE RELEASE REACTION; THROMBOCYTOPENIA; BIOSYNTHESIS; CALCIUM SIGNALING; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; THROMBOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE DIPHOSPHATE; ADRENERGIC ALPHA-AGONISTS; ANTICOAGULANTS; ANTIGENS, CD; BLOOD PLATELETS; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPINEPHRINE; GTP-BINDING PROTEINS; HEPARIN; HUMANS; ISOENZYMES; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET AGGREGATION; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, IGG; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; THROMBOCYTOPENIA; TYROSINE;

EID: 0034668382     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.10.3439     Document Type: Article

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