The C-class chemokine, lymphotactin, impairs the induction of Th1-type lymphokines in human CD4+ T cells

Blood

Volumn 96, Issue 2, 2000, Pages 420-428

  Cerdan, Chantal ^a   Serfling, Edgar ^b   Olive, Daniel ^b  

^a INSERM   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOATTRACTANT; CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; LYMPHOKINE; LYMPHOTACTIN; RANTES;

ARTICLE; CELL PROLIFERATION; CYTOKINE PRODUCTION; DOWN REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEUKOCYTE MIGRATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTION REGULATION;

EID: 0034662133     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.2.420     Document Type: Article

References (64)

1. Rollins BJ. Chemokines. Blood. 1997;90:909.
2. Kennedy J, Keiner GS, Kleyensteuber S, et al. Molecular cloning and functional characterization of human lymphotactin. J. Immunol. 1995;155: 203.
3. + T lymphocytes. Eur J Immunol. 1995;25:1744.
4. Yoshida T, Imai T, Kakizaki M, Nishimura M, Yoshie O. Molecular cloning of a novel C or γ chemokine, SCM-1. FEBS Lett. 1995;360:155.
5. Pan Y, Lloyd C, Zhou H et al. Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature. 1997;387:611.
6. 3C motif. Nature. 1997;385:640.
7. + T cells. J Biol Chem. 1997;272:8817.
8. Blanchi G, Sozzani S, Zlotnik A, Mantovani A, Allavena P. Migratory response of human natural killer cells to lymphotactin. EurJ Immunol. 1996; 26:3238.
9. Hedrick JA, Saylor S, Figueroa D, et al. Lymphotactin is produced by NK cells and attracts both NK cells and T cells in vivo. J Immunol. 1997;158: 1533.
10. Maghazachi AA, Skalhegg BS, Rolstad B, Al-Aoukaty A. Interferon-inducible protein-10 and lymphotactin induce the chemotaxis and mobilization of intracellular calcium in natural killer cells through pertussis toxin-sensitive and-insensitive heterotrimeric G-proteins. FASEB J. 1997;11:765.
11. Bacon KB, Premack BA, Gardner P, Schall TJ. Activation of dual T cell signaling pathways by the chemokine RANTES. Science. 1995;269:1727.
12. Kimata H, Yoshida A, Ishioka C, Fujimoto M, Lindley I, Furusho K. RANTES and macrophage inflammatory prolein 1α selectively enhance immunoglobulin (IgE) and IgG4 production by human B cells. J Exp Med. 1996;183:2397.
13. Szabo MC, Butcher EC, McIntyre BW, Schall TJ, Bacon KB. RANTES stimulation of T lymphocyte adhesion and activation: role for LFA-1 and ICAM-3. EurJ Immunol. 1997;27:1061.
14. Taub DD, Turcovski-Corrales SM, Key ML, Longo DL, Murphy, WJ. Chemokines and T lymphocyte activation: I. Beta Chemokines costimulate human T lymphocyte activation in vitro. J Immunol. 1996; 156:2095
15. Lloyd AR, Oppenheim JJ, Kelvin DJ, Taub DD. Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins. J Immunol. 1996;15:932.
16. Van Snick J, Houssiau F, Proost P, Van Damme J, Renauld J-C. I-309/T cell activation gene-3 chemokine protects murine T cells lymphomas against dexamethasone-induced apoptosis. J Immunol. 1996;157:2570.
17. Yoshida T, Imai T, Kakizaki M, Nishimura M, Tagaki S, Yoshie O. Identification of single C motif-1/lymphotactin receptor, XCR1. J Biol Chem. 1998;273:16551.
18. Boismenu R, Feng L, Xia YY, Chang JCC, Havran WL. Chemokine expression by intraepithelial γδ T cells. Implications for the recruitment of inflammatory cells to damaged epithelia. J Immunol. 1996; 157:985.
19. Rumsaeng V, Vliagoftis H, Oh CK, Metcalfe DD. Lymphotactin gene expression in mast cells following Fc∈ receptor I aggregation. Modulation by TGF-β, IL-4, dexamethasone, and cyclosporin A. J Immunol. 1997;158:1353.
20. Cerdan C, Martin Y, Courcoul MA, et al. Prolonged IL-2 receptor alpha/CD25 expression after T cell activation via the adhesion molecules CD2 and CD28. Demonstration of combined transcriptional and post-transcriptional regulation. J Immunol. 1992;149:2255.
21. Cerdan, C, Martin Y, Courcoul MA, Mawas C, Birg F, Olive D. CD28 costimulation up-regulates long-term IL-2Rβ expression in human T cells through combined transcriptional and post-transcriptional regulation. J Immunol. 1995;154:1007.
22. Olive D, Pages F, Klasen S, et al. Stimulation via the CD28 molecule: regulation of signaling, cytokine production and cytokine receptor expression. Fundam Clin Immunol. 1994;2:185.
23. Thompson CB, Lindsten T, Ledbetter JA, et al. CD28 activation pathways regulates the production of multiple T-cell derived lymphokines/cytokines. Proc Natl Acad Sci U S A. 1989;86:1333.
24. Herald KC, Lu J, Rulifson I, et al. Regulation of C-C chemokine production by murine T cells by CD28/B7 costimulation. J Immunol. 1997;159: 4150.
25. Collette Y, Benziane A, Razanajaona D, Olive D. Distinct regulation of T-cell death by CD28 depending on both its aggregation and T-cell receptor triggering: a role for Fas-FasL. Blood. 1998; 92:1.
26. Loetscher P, Seitz M, Baggiolini M, Moser B. Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med. 1996;184:569.
27. + T cells. Science. 1997;276:273.
28. Riley JL, Carroll RG, Levine BL, et al. Intrinsic resistance to T cell infection with HIV type 1 induced by CD28 costimulation. J Immunol. 1997; 158:5545.
29. Carroll RG, Riley JL, Levine BL, Blair PJ, St Louis DC, June CH. The role of co-stimulation in regulation of chemokine receptor expression and HIV-1 infection in primary T lymphocytes. Semin Immunol. 1998;10:195.
30. Moriuchi H, Moriuchi M, Fauci AS. Cloning and analysis of the promoter region of CCR5, a coreceptor for HIV-1 entry. J Immunol. 1997;159: 5441.
31. + T cells, via an IL-2 dependent mechanism. Eur J Immunol. 1999;29: 2443.
32. Bagnasco M, Nunes J, Lopez M, et al. T cell activation via the CD2 molecule is associated with protein kinase C translocation from the cytosol to the plasma membrane. Eur J Immunol. 1989;19: 823.
33. Ott M, Emiliani S, Van LC, et al. Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway. Science. 1997;275:1481.
34. Tanaka N, Abe H, Yagita H, Okumura K, Nakamura M, Sugamura K. Itk, a T cell-specific tyrosine kinase, is required for CD2-mediated interleukin-2 promoter activation in the human T cell line Jurkat. Eur J Immunol. 1997;27:834.
35. Penix L, Weaver WM, Pang Y, Young HA, Wilson CB. Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells. J Exp Med. 1993; 178:1483.
36. Li-Weber M, Salgame P, Hu C, et al. Th-2-specific protein/DNA interactions at the proximal nuclear factor-AT site contribute to the functional activity of the human IL-4 promoter. J Immunol. 1998; 161:1380.
37. Chupvilo S, Zimmer M, Kerstan A, et al. Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells. Immunity. 1999;10:261.
38. Yang W-C, Olive D. Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway. Eur J Immunol. 1999;29:1842.
39. Smith KA, Cantrell DA. Interleukin 2 regulates its own receptors. Proc Natl Acad Sci USA. 1985; 82:864.
40. Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol. 1997;15:707.
41. Hoogewert AJ, Kuschert GS, Proudfoot AE, et al. Glycosaminoglycans mediate cell surface oligomerisation of chemokines. Biochemistry. 1997;36: 13570.
42. Hautamaa D, Merica R, Chen Z, Jenkins MK. Murine lymphotactin: gene structure, post-translational modification and inhibition of expression by CD28 costimulation. Cytokine. 1997;9:375.
43. Zhou Z, Kim Y-J, Pollock K, et al. Macrophage inflammatory protein-la rapidly modulates its receptors and inhibits the anti-CD3 mAb-mediated proliferation of T lymphocytes. J Immunol. 1993; 151:4333.
44. O'Garra A, McEvoy LM, Zlotnik A. T-cell subsets: chemokine receptors guide the way. Curr Biol. 1998;8:R646.
45. Loetscher P, Uguccioni M, Bordoli L, Baggiolini M, Moser B. CCR5 is characteristic of Th1 lymphocytes. Nature. 1998;391:344.
46. Sallusto F, Mackay CR, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science. 1997;277:2005.
47. Reem GH, Yeh NH. Interleukin 2 regulates expression of its receptor and synthesis of gamma interferon by human T lymphocytes. Science. 1984;225:429.
48. Baggiolini M, Dewald B, Moser B. Human chemokines: an update. Annu Rev Immunol. 1997;15: 675.
49. Rooney JW, Hodge MR, McCaffrey PG, Rao A, Glimcher LH. A common factor regulates both Th1- and Th2-specific cytokine gene expression. EMBO J. 1994;13:625.
50. Rincon M, Flavell RA. Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. Mol Cell Biol. 1997;17:1522.
51. Ranger AM, Hodge MR, Gravallese EM, et al. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 1998;8:125.
52. Yoshida H, Nishina H, Takimoto H, et al. The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity. 1998;8:115.
53. Glimcher LH, Singh H. Transcription factors in lymphocyte development - T and B cells get together. Cell. 1999;96:13.
54. Schuh K, Twardzik T, Kneitz B, Heyer J, Schimpl A, Serfling E. The interleukin 2 receptor α chain/ CD25 promoter is a target for nuclear factor of activated T cells. J Exp Med. 1998;188:1369.
55. Al-Aoukaty A, Rolstad B, Maghazachi AA. Recruitment of pleckstrin and phosphoinositide 3-kinase gamma into the cell membranes, and their association with G beta gamma after activation of NK cells with chemokines. J Immunol. 1999;162: 3249.
56. FAK and ZAP-70 in human T cells. J Exp Med. 1996;184:873.
57. Dilloo D, Bacon KB, Holden W, et al. Combined chemokine and cytokine gene transfer enhances antitumor immunity. Nat Med. 1996;2:1090.
58. Cao X, Zhang W, He L, et al. Lymphotactin genemodified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity. J Immunol. 1998; 161:6238.
59. Lillard JW Jr, Boyaka PN, Hedrick JA, Zlotnik A, McGhee JR. Lymphotactin acts as an innate mucosal adjuvant. J Immunol. 1999;162:1959.
60. Emtage PCR, Wan Y, Hitt M, et al. Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models. Hum Gene Ther. 1999;10:697.
61. Krummel MF, Allison JP. CTLA-4 engagement inhibits IL-2 accumulation and cell-cycle progression upon activation of resting T cells. J Exp Med. 1996;183:2533.
62. Desbarats J, Duke RC, Newell MK. Newly discovered role for Fas ligand in the cell-cycle arrest of CD4+ T cells. Nat Med. 1998;4:1377.
63. Paul WE, Seder RA. Lymphocyte responses and cytokines. Cell. 1994;76:241.
64. Constant SL, Bottomly K. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu Rev Immunol. 1997;15:297.