Phosphonamidate and phosphothioate dipeptides as potential inhibitors of VanX

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 10, 2000, Pages 1085-1087

  Yang, Ke Wu ^a   Brandt, Jeffrey J ^a   Chatwood, Lisa L ^a   Crowder, Michael W ^a  

^a MIAMI UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[(1 AMINOETHYL)HYDROXYPHOSPHINYL] ALANINE; [(AMINOETHYL)HYDROXYPHOSPHINYL] THIOLACETIC ACID; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION;

ALANINE; BACTERIAL PROTEINS; BETA-LACTAMASES; BINDING SITES; DIPEPTIDES; KINETICS; ORGANOPHOSPHORUS COMPOUNDS; RECOMBINANT PROTEINS; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE; STRUCTURE-ACTIVITY RELATIONSHIP; VANCOMYCIN RESISTANCE;

EID: 0034657545     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00186-4     Document Type: Article

References (17)

1. Wu Z., Wright G.D., Walsh C.T. Biochem. 34:1995;2455.
2. Walsh C.T., Fisher S.L., Park I.S., Prahalad M., Wu Z. Chem. Biol. 3:1996;21.
3. Reynolds P.E., Depardieu F., Dutka-Malen S., Arthur M., Courvalin P. Mol. Microbiol. 13:1994;1065.
4. Wu Z., Walsh C.T. J. Am. Chem. Soc. 118:1996;1785.
5. Wu Z., Walsh C.T. Proc. Nat. Acad. Sci. USA. 92:1995;11603.
6. Bussiere D.E., Pratt S.D., Katz L., Severin J.M., Holzman T., Park C.H. Mol. Cell. 2:1998;75.
7. Kaplan A.P., Bartlett P.A. Biochem. 30:1991;8165.
8. Bartlett P.A., Marlowe C.K. Biochem. 22:1983;4618.
9. Hanson J.E., Kaplan A.P., Bartlett P.A. Biochem. 28:1989;6294.
10. Jacobsen N.E., Bartlett P.A. J. Am. Chem. Soc. 103:1981;654.
11. Tronrud D.E., Holden H.M., Matthews B.W. Science. 235:1987;571.
12. Bartlett P.A., Marlowe C.K. Science. 235:1987;569.
13. Oleksyszyn, J.; Subotkowska, L. Mastalerg, P. Synthesis 1979, 985.
14. Ellsworth B.A., Tom N.J., Bartlett P.A. Chem. Biol. 3:1996;37.
15. Brandt J.J., Chatwood L.L., Yang K.W., Crowder M.W. Anal. Biochem. 272:1999;94.
16. Webb, J. L. Enzyme and Metabolic Inhibitors; Academic: New York, 1963; Vol. 1.
17. Crowder M.W., Walsh T.R., Banovic L., Pettit M., Spencer J. Antimicrob. Agents Chemother. 42:1998;921.