메뉴 건너뛰기




Volumn 164, Issue 10, 2000, Pages 5156-5166

Differential requirement for p56(lck) in HIV-tat versus TNF-induced cellular responses: Effects on NF-κB, activator protein-1, c-Jun N-terminal kinase, and apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN P56; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR; DNA BINDING PROTEIN; HYDROGEN PEROXIDE; I KAPPA B; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE LCK; REACTIVE OXYGEN METABOLITE; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0034656414     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.10.5156     Document Type: Article
Times cited : (47)

References (51)
  • 1
    • 0027618875 scopus 로고
    • Tat and the HIV-1 promoter
    • Jones, K. A. 1993. Tat and the HIV-1 promoter. Curr. Opin. Cell Biol. 5:461.
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 461
    • Jones, K.A.1
  • 2
    • 0032855497 scopus 로고    scopus 로고
    • Multifaceted activities of the HIV-1 transactivator of the transcription. Tat
    • Jeang, K-T., J. Xiao, and E. A. Rich. 1999. Multifaceted activities of the HIV-1 transactivator of the transcription. Tat. J. Biol. Chem. 274:28837.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28837
    • Jeang, K.-T.1    Xiao, J.2    Rich, E.A.3
  • 3
    • 0028168513 scopus 로고
    • HIV type 1 Tat protein induces immunoglobulin and interleukin 6 synthesis by uninfected peripheral blood mononuclear cells
    • Rautonen J., N. Rautonen, N. L. Martin, and D. W. Wara. 1994. HIV type 1 Tat protein induces immunoglobulin and interleukin 6 synthesis by uninfected peripheral blood mononuclear cells. AIDS Res. Hum. Retroviruses 10:781.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 781
    • Rautonen, J.1    Rautonen, N.2    Martin, N.L.3    Wara, D.W.4
  • 4
    • 0025203763 scopus 로고
    • HIV-1 tat gene induces tumor necrosis factor-β (lymphotoxin) in a human B-lymphoblastoid cell line
    • Sastry K. J., H. R. Reddy, R. Pandita, K. Totpal, and B. B. Aggarwal. 1990. HIV-1 tat gene induces tumor necrosis factor-β (lymphotoxin) in a human B-lymphoblastoid cell line. J. Biol. Chem. 265:20091.
    • (1990) J. Biol. Chem. , vol.265 , pp. 20091
    • Sastry, K.J.1    Reddy, H.R.2    Pandita, R.3    Totpal, K.4    Aggarwal, B.B.5
  • 6
    • 0026747802 scopus 로고
    • Human immunodeficiency virus type 1 tat gene up-regulates interleukin 4 receptors on a human B-lymphoblastoid cell line
    • Puri, R. K., and B. B. Aggarwal. 1992. Human immunodeficiency virus type 1 tat gene up-regulates interleukin 4 receptors on a human B-lymphoblastoid cell line. Cancer Res. 52:787.
    • (1992) Cancer Res. , vol.52 , pp. 787
    • Puri, R.K.1    Aggarwal, B.B.2
  • 7
    • 0029817040 scopus 로고    scopus 로고
    • Transcriptional upregulation of interleukin-4 receptors by human immunodeficiency virus type 1 tat gene
    • Husain, S. R., P. Leland, B. B. Aggarwal, and R. P. Puri. 1996. Transcriptional upregulation of interleukin-4 receptors by human immunodeficiency virus type 1 tat gene. AIDS Res. Hum. Retroviruses 12:1349.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 1349
    • Husain, S.R.1    Leland, P.2    Aggarwal, B.B.3    Puri, R.P.4
  • 8
    • 0028044514 scopus 로고
    • HIV-1 transactivator protein Tat induces proliferation and TGF β expression in human articular chondrocytes
    • Lotz, M., I. Clark-Lewis, and V. Ganu. 1994. HIV-1 transactivator protein Tat induces proliferation and TGF β expression in human articular chondrocytes. J. Cell Biol. 124:365.
    • (1994) J. Cell Biol. , vol.124 , pp. 365
    • Lotz, M.1    Clark-Lewis, I.2    Ganu, V.3
  • 9
    • 0027220944 scopus 로고
    • The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence
    • Barillari, G., R. Gendelman, R. C. Gallo, and B. Ensoli. 1993. The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proc. Natl. Acad. Sci. USA 90:7941.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7941
    • Barillari, G.1    Gendelman, R.2    Gallo, R.C.3    Ensoli, B.4
  • 10
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • Ensoli, B., L. Bounaguro, G. Barillari, V. Fiorelli, R. Gendelman, R. A. Morgan, P. Wingfield, and R. C. Gallo. 1993. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 67:277.
    • (1993) J. Virol. , vol.67 , pp. 277
    • Ensoli, B.1    Bounaguro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6    Wingfield, P.7    Gallo, R.C.8
  • 12
    • 0039129153 scopus 로고    scopus 로고
    • Expression of human immunodeficiency virus type 1 tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells
    • Sastry, K. J., M. C. Marin, P. N. Nehete, K. McConnell, A. K. El-Naggar, and T. J. McDonnell. 1996. Expression of human immunodeficiency virus type 1 tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells. Oncogene 13:487.
    • (1996) Oncogene , vol.13 , pp. 487
    • Sastry, K.J.1    Marin, M.C.2    Nehete, P.N.3    McConnell, K.4    El-Naggar, A.K.5    McDonnell, T.J.6
  • 14
    • 0030860877 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1-tat protein induces the cell surface expression of endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in human endothelial cells
    • Dhawan, S., R. K. Puri, A. Kumar, H. Duplan, J-M. Masson, and B. B. Aggarwal. 1997. Human immunodeficiency virus-1-tat protein induces the cell surface expression of endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in human endothelial cells. Blood 90:1535.
    • (1997) Blood , vol.90 , pp. 1535
    • Dhawan, S.1    Puri, R.K.2    Kumar, A.3    Duplan, H.4    Masson, J.-M.5    Aggarwal, B.B.6
  • 15
    • 0032733648 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1-tat induces matrix metalloproteinase-9 in monocytes through protein tyrosine phosphatase-mediated activation of nuclear transcription factor NF-κB
    • Kumar A., S. Dhawan, A. Mukhopadhyay, and B. B. Aggarwal. 1999. Human immunodeficiency virus-1-tat induces matrix metalloproteinase-9 in monocytes through protein tyrosine phosphatase-mediated activation of nuclear transcription factor NF-κB. FEBS Lett. 462:140.
    • (1999) FEBS Lett. , vol.462 , pp. 140
    • Kumar, A.1    Dhawan, S.2    Mukhopadhyay, A.3    Aggarwal, B.B.4
  • 16
    • 0029940987 scopus 로고    scopus 로고
    • Activation of transcription factor NF-κB by the Tat protein of human immunodeficiency virus type 1
    • Demarchi, F., F. d'Adda di Fagagna, A. Falaschi, and M. Giacca. 1996. Activation of transcription factor NF-κB by the Tat protein of human immunodeficiency virus type 1. J. Virol. 70:4427.
    • (1996) J. Virol. , vol.70 , pp. 4427
    • Demarchi, F.1    D'Adda Di Fagagna, F.2    Falaschi, A.3    Giacca, M.4
  • 17
    • 0030040212 scopus 로고    scopus 로고
    • Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-κB binding and protein kinase C activity in primary human astrocytes
    • Conant K., M. Ma, A. Nath, and E. O. Major. 1996. Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-κB binding and protein kinase C activity in primary human astrocytes. J. Virol. 70:1384.
    • (1996) J. Virol. , vol.70 , pp. 1384
    • Conant, K.1    Ma, M.2    Nath, A.3    Major, E.O.4
  • 18
    • 0032528334 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1 tat protein activates c-Jun N-terminal kinase and activator protein-1
    • Kumar, A., S. K. Manna, S. Dhawan, and B. B. Aggarwal. 1998. Human immunodeficiency virus-1 tat protein activates c-Jun N-terminal kinase and activator protein-1. J. Immunol. 161:776.
    • (1998) J. Immunol. , vol.161 , pp. 776
    • Kumar, A.1    Manna, S.K.2    Dhawan, S.3    Aggarwal, B.B.4
  • 20
    • 0026705903 scopus 로고
    • Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
    • Straus, D. B., and A. Weiss. 1992. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70:585.
    • (1992) Cell , vol.70 , pp. 585
    • Straus, D.B.1    Weiss, A.2
  • 21
    • 0032145709 scopus 로고    scopus 로고
    • The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism
    • Dutartre, H., M. Harris, D. Olive, and Y. Collette. 1998. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism. Virology 247: 200.
    • (1998) Virology , vol.247 , pp. 200
    • Dutartre, H.1    Harris, M.2    Olive, D.3    Collette, Y.4
  • 23
    • 0031746911 scopus 로고    scopus 로고
    • lck is required for triggering NF-κB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4
    • lck is required for triggering NF-κB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4. J. Virol. 72:6207.
    • (1998) J. Virol. , vol.72 , pp. 6207
    • Briant, L.1    Robert-Hebmann, V.2    Acquaviva, C.3    Pelchen-Matthews, A.4    Marsh, M.5    Devaux, C.6
  • 24
    • 0032193229 scopus 로고    scopus 로고
    • Lck-independent inhibition of T cell antigen response by the HIV gp120
    • Gratton, S., M. Julius, and R. P. Sekaly. 1998. Lck-independent inhibition of T cell antigen response by the HIV gp120. J. Immunol. 161:3551.
    • (1998) J. Immunol. , vol.161 , pp. 3551
    • Gratton, S.1    Julius, M.2    Sekaly, R.P.3
  • 25
    • 0033595175 scopus 로고    scopus 로고
    • A single base mutation in the 5 splice site of intron 7 of the lck gene is responsible for the deletion of exon 7 in lck mRNA of the JCaM1 cell line
    • Rouer, E., F. Brule, and R. Benarous. 1999. A single base mutation in the 5 splice site of intron 7 of the lck gene is responsible for the deletion of exon 7 in lck mRNA of the JCaM1 cell line. Oncogene 18:4262.
    • (1999) Oncogene , vol.18 , pp. 4262
    • Rouer, E.1    Brule, F.2    Benarous, R.3
  • 26
    • 0032557458 scopus 로고    scopus 로고
    • Overexpression of Mn-superoxide dismutase suppresses TNF induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1
    • Manna S. K., H. J. Zhang, T. Ya, L. W. Oberley, and B. B. Aggarwal. 1998. Overexpression of Mn-superoxide dismutase suppresses TNF induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1. J. Biol. Chem. 273:13245.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13245
    • Manna, S.K.1    Zhang, H.J.2    Ya, T.3    Oberley, L.W.4    Aggarwal, B.B.5
  • 27
    • 0033582819 scopus 로고    scopus 로고
    • Activation of NF-κB by RANK requires TRAF6 and NF-κB-inducing kinase (NIK): Identification of a novel TRAF6 interaction motif
    • Darnay, B. G., J. Ni, P. A. Moore, and B. B. Aggarwal. 1999. Activation of NF-κB by RANK requires TRAF6 and NF-κB-inducing kinase (NIK): identification of a novel TRAF6 interaction motif. J. Biol. Chem. 274:7724.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7724
    • Darnay, B.G.1    Ni, J.2    Moore, P.A.3    Aggarwal, B.B.4
  • 28
    • 0032715311 scopus 로고    scopus 로고
    • Silymarin suppresses TNF-induced activation of nuclear transcription factor-κB, c-jun N-terminal kinase and apoptosis
    • Manna S. K., A. Mukhopadhyay, N. T. Van, and B. B. Aggarwal. 1999. Silymarin suppresses TNF-induced activation of nuclear transcription factor-κB, c-jun N-terminal kinase and apoptosis. J. Immunol. 163:6800.
    • (1999) J. Immunol. , vol.163 , pp. 6800
    • Manna, S.K.1    Mukhopadhyay, A.2    Van, N.T.3    Aggarwal, B.B.4
  • 29
    • 0030747128 scopus 로고    scopus 로고
    • NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules
    • Baeuerle, P. A., and V. R. Baichwal. 1997. NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules Adv. Immunol. 65:111.
    • (1997) Adv. Immunol. , vol.65 , pp. 111
    • Baeuerle, P.A.1    Baichwal, V.R.2
  • 30
    • 0030771914 scopus 로고    scopus 로고
    • 2 in NF-κB activation by either cytokine in both primary and transformed endothelial cells
    • 2 in NF-κB activation by either cytokine in both primary and transformed endothelial cells. J. Biol. Chem. 272:25941.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25941
    • Bowie, A.G.1    Moynagh, P.N.2    O'Neill, L.A.J.3
  • 32
    • 0028172869 scopus 로고
    • Inducible phosphorylation of IκBγ is not sufficient for its dissociation from NF-κB and in inhibited hy protease inhibitors
    • Finco, T. S., A. A. Beg, and A. S. Baldwin. 1994. Inducible phosphorylation of IκBγ is not sufficient for its dissociation from NF-κB and in inhibited hy protease inhibitors. Proc: Natl. Acad. Sci. USA 91:11884.
    • (1994) Proc: Natl. Acad. Sci. USA , vol.91 , pp. 11884
    • Finco, T.S.1    Beg, A.A.2    Baldwin, A.S.3
  • 33
    • 0029956644 scopus 로고    scopus 로고
    • Site-specific tyrosine phosphorylation of IκBα negatively regulates its inducible phosphorylalion and degradation
    • Singh, S., B. G. Darney, and B. B. Aggarwal. 1996. Site-specific tyrosine phosphorylation of IκBα negatively regulates its inducible phosphorylalion and degradation. J. Biol. Chem. 271:31049.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31049
    • Singh, S.1    Darney, B.G.2    Aggarwal, B.B.3
  • 34
    • 0033538340 scopus 로고    scopus 로고
    • Differential IκB kinase activation and IκBα degradation by interleukin-1β and tumor necrosis factor-α in human U937 monocytic cells. Evidence for additional regulatory steps in κB-dependent transcription
    • Nasuhara, Y., I. M. Adcock, M. Catley, P. J. Barnes, and R. Newton. 1999. Differential IκB kinase activation and IκBα degradation by interleukin-1β and tumor necrosis factor-α in human U937 monocytic cells. Evidence for additional regulatory steps in κB-dependent transcription. J. Biol. Chem. 274:19965.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19965
    • Nasuhara, Y.1    Adcock, I.M.2    Catley, M.3    Barnes, P.J.4    Newton, R.5
  • 36
    • 0029947996 scopus 로고    scopus 로고
    • MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of IκBα
    • Hirano, M., S. Osada, T. Aoki, S. Hirai, M. Hosaka, J. Inoue, and S. Ohno. 1996. MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of IκBα. J. Biol. Chem. 271:13234.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13234
    • Hirano, M.1    Osada, S.2    Aoki, T.3    Hirai, S.4    Hosaka, M.5    Inoue, J.6    Ohno, S.7
  • 37
    • 0033451738 scopus 로고    scopus 로고
    • TNF-induced signaling in apoptosis
    • Rath, P. C., and B. B. Aggarwal. 1999. TNF-induced signaling in apoptosis J. Clin. Immunol. 19:350.
    • (1999) J. Clin. Immunol. , vol.19 , pp. 350
    • Rath, P.C.1    Aggarwal, B.B.2
  • 38
    • 0030761189 scopus 로고    scopus 로고
    • The activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505
    • Hardwick, J. S., and B. M. Sefton. 1997. The activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505. J. Biol. Chem. 272:25429.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25429
    • Hardwick, J.S.1    Sefton, B.M.2
  • 39
    • 0033557695 scopus 로고    scopus 로고
    • Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-κB activation and gene expression
    • Manna, S. K., and B. B. Aggarwal. 1999. Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-κB activation and gene expression. J. Immunol. 162:2095.
    • (1999) J. Immunol. , vol.162 , pp. 2095
    • Manna, S.K.1    Aggarwal, B.B.2
  • 40
    • 0030613758 scopus 로고    scopus 로고
    • NF-κB activation: The IκB kinase revealed?
    • Stancovski, I., and D. Baltimore. 1997. NF-κB activation: the IκB kinase revealed? Cell 91:299.
    • (1997) Cell , vol.91 , pp. 299
    • Stancovski, I.1    Baltimore, D.2
  • 41
    • 0033582440 scopus 로고    scopus 로고
    • The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling
    • Denny, M. F., H. C. Kaufman, A. C. Chan, and D. B. Straus. 1999. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling. J. Biol. Chem. 274: 5146.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5146
    • Denny, M.F.1    Kaufman, H.C.2    Chan, A.C.3    Straus, D.B.4
  • 42
    • 0030821961 scopus 로고    scopus 로고
    • L-selectin activates JNK via src-like tyrosine kinases and the small G-protein rac
    • Brenner, B., S. Weinmann, H. Grassme, F. Lang, O. Linderkamp, and E. Gulbins. 1997. L-selectin activates JNK via src-like tyrosine kinases and the small G-protein Rac. Immunology 92:214.
    • (1997) Immunology , vol.92 , pp. 214
    • Brenner, B.1    Weinmann, S.2    Grassme, H.3    Lang, F.4    Linderkamp, O.5    Gulbins, E.6
  • 43
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke, T. M., and P. A. Sandstrom. 1994. Oxidative stress as a mediator of apoptosis. Immunol. Today 15:7.
    • (1994) Immunol. Today , vol.15 , pp. 7
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 45
    • 0033615032 scopus 로고    scopus 로고
    • Overexpression of γ-glutamylcysteine synthetase abolishes tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activator protein-1
    • Manna, S. K., M. T. Kuo, and B. B. Aggarwal. 1999. Overexpression of γ-glutamylcysteine synthetase abolishes tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activator protein-1 Oncogene 18:4371.
    • (1999) Oncogene , vol.18 , pp. 4371
    • Manna, S.K.1    Kuo, M.T.2    Aggarwal, B.B.3
  • 47
    • 0032514683 scopus 로고    scopus 로고
    • Cell-cycle arrest and apoptosis hypersusceptibility as a consequence of Lck deficiency in nontransformed T lymphocytes
    • al-Ramadi, B. K., H. Zhang, and A. L. Bothwell. 1998. Cell-cycle arrest and apoptosis hypersusceptibility as a consequence of Lck deficiency in nontransformed T lymphocytes. Proc. Natl. Acad. Sci. USA 95:12498.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12498
    • Al-Ramadi, B.K.1    Zhang, H.2    Bothwell, A.L.3
  • 50
    • 0342872052 scopus 로고    scopus 로고
    • HIV-1-Tat protein as a potential AIDS vaccine
    • Goldstein, G. 1999. HIV-1-Tat protein as a potential AIDS vaccine. Nat. Med. 1:960.
    • (1999) Nat. Med. , vol.1 , pp. 960
    • Goldstein, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.