p27(Kip1) regulates cell cycle withdrawal of late multipotent progenitor cells in the mammalian retina

Developmental Biology

Volumn 219, Issue 2, 2000, Pages 299-314

  Levine, Edward M ^a   Close, Jennie ^a   Fero, Matthew ^b   Ostrovsky, Aaron ^a   Reh, Thomas A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

CDK inhibitor; Gene gun; Glia; Neurogenesis; Neuron; Particle mediated gene transfer; Proliferation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P27;

ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; MUELLER CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLIGODENDROGLIA; OPTIC NERVE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA; RETINA MALFORMATION; STEM CELL;

MAMMALIA;

EID: 0034643089     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9622     Document Type: Article

References (47)

1. al-Ubaidi M. R., Hollyfield J. G., Overbeek P. A., Baehr W. Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice. Proc. Natl. Acad. Sci. USA. 89:1992;1194-1198.
2. Anchan R. M., Reh T. A. Transforming growth factor-beta-3 is mitogenic for rat retinal progenitor cells in vitro. J. Neurobiol. 28:1995;133-145.
3. Anchan R. M., Reh T. A., Angello J., Balliet A., Walker M. EGF and TGF-alpha stimulate retinal neuroepithelial cell proliferation in vitro. Neuron. 6:1991;923-936.
4. Arnold D., Feng L., Kim J., Heintz N. A strategy for the analysis of gene expression during neural development. Proc. Natl. Acad. Sci. USA. 91:1994;9970-9974.
5. Casaccia-Bonnefil P., Tikoo R., Kiyokawa H., Friedrich V. Jr., Chao M. V., Koff A. Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. Genes Dev. 11:1997;2335-2346.
6. Chen P., Segil N. p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti. Development. 126:1999;1581-1590.
7. Cheng M., Olivier P., Diehl J. A., Fero M., Roussel M. F., Roberts J. M., Sherr C. J. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18:1999;1571-1583.
8. Chow L., Levine E. M., Reh T. A. The nuclear receptor transcription factor, retinoid-related orphan receptor beta, regulates retinal progenitor proliferation. Mech. Dev. 77:1998;149-164.
9. Coats S., Whyte P., Fero M. L., Lacy S., Chung G., Randel E., Firpo E., Roberts J. M. A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells. Curr. Biol. 9:1999;163-173.
10. Conlon I., Raff M. Size control in animal development. Cell. 96:1999;235-244.
11. de Nooij J. C., Letendre M. A., Hariharan I. K. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell. 87:1996;1237-1247.
12. Durand B., Fero M. L., Roberts J. M., Raff M. C. p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation. Curr. Biol. 8:1998;431-440.
13. Durand B., Gao F. B., Raff M. Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation. EMBO J. 16:1997;306-317.
14. Edlund T., Jessell T. M. Progression from extrinsic to intrinsic signaling in cell fate specification: A view from the nervous system. Cell. 96:1999;211-224.
15. Fero M. L., Rivkin M., Tasch M., Porter P., Carow C. E., Firpo E., Polyak K., Tsai L. H., Broudy V., Perlmutter R. M., Kaushansky K., Roberts J. M. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell. 85:1996;733-744.
16. Friessen A. J., Miskimins W. K., Miskimins R. Cyclin-dependent kinase inhibitor p27kip1 is expressed at high levels in cells that express a myelinating phenotype. J. Neurosci. Res. 50:1997;373-382.
17. Holt C. E., Bertsch T. W., Ellis H. M., Harris W. A. Cellular determination in the Xenopus retina is independent of lineage and birth date. Neuron. 1:1988;15-26.
18. Hong Y., Roy R., Ambros V. Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans. Development. 125:1998;3585-3597.
19. Humphrey M. F., Chu Y., Mann K., Rakoczy P. Retinal GFAP and bFGF expression after multiple argon laser photocoagulation injuries assessed by both immunoreactivity and mRNA levels. Exp. Eye Res. 64:1997;361-369.
20. Kiyokawa H., Kineman R. D., Manova-Todorova K. O., Soares V. C., Hoffman E. S., Ono M., Khanam D., Hayday A. C., Frohman L. A., Koff A. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell. 85:1996;721-732.
21. Lane M. E., Sauer K., Wallace K., Jan Y. N., Lehner C. F., Vaessin H. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell. 87:1996;1225-1235.
22. Lee M. H., Nikolic M., Baptista C. A., Lai E., Tsai L. H., Massague J. The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. Proc. Natl. Acad. Sci. USA. 93:1996;3259-3263.
23. Lillien L., Cepko C. Control of proliferation in the retina: Temporal changes in responsiveness to FGF and TGF alpha. Development. 115:1992;253-266.
24. Lillien L., Wancio D. Changes in epidermal growth factor receptor expression and competence to generate glia regulate timing and choice of differentiation in the retina. Mol. Cell. Neurosci. 10:1998;296-308.
25. Lowenheim H., Furness D. N., Kil J., Zinn C., Gultig K., Fero M. L., Frost D., Gummer A. W., Roberts J. M., Rubel E. W., Hackney C. M., Zenner H. P. Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of Corti. Proc. Natl. Acad. Sci. USA. 96:1999;4084-4088.
26. Ma C., Papermaster D., Cepko C. L. A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice. Proc. Natl. Acad. Sci. USA. 95:1998;9938-9943.
27. Malhotra S. K., Shnitka T. K., Elbrink J. Reactive astrocytes - A review. Cytobios. 61:1990;133-160.
28. Nakayama K., Ishida N., Shirane M., Inomata A., Inoue T., Shishido N., Horii I., Loh D. Y. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell. 85:1996;707-720.
29. Ohnuma S., Philpott A., Wang K., Holt C. E., Harris W. A. p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retina. Cell. 99:1999;499-510.
30. Reh T. A. Cell-specific regulation of neuronal production in the larval frog retina. J. Neurosci. 7:1987;3317-3324.
31. Reh T. A. Determination of cell fate during retinal histogenesis: Intrinsic and extrinsic mechanisms. Lam M.-K., Shatz C. J. Development of the Visual System. 1991;79-94 MIT Press, Cambridge.
32. Reh T. A. Cellular interactions determine neuronal phenotypes in rodent retinal cultures. J. Neurobiol. 23:1992;1067-1083.
33. Reh T. A., Levine E. M. Multipotential stem cells and progenitors in the vertebrate retina. J. Neurobiol. 36:1998;206-220.
34. Ridet J. L., Malhotra S. K., Privat A., Gage F. H. Reactive astrocytes: Cellular and molecular cues to biological function. Trends Neurosci. 20:1997;570-577.
35. 3H]thymidine. Smelser G. The Structure of the Eye. 1961;Academic Press, New York.
36. Tikoo R., Casaccia-Bonnefil P., Chao M. V., Koff A. Changes in cyclin-dependent kinase 2 and p27kip1 accompany glial cell differentiation of central glia-4 cells. J. Biol. Chem. 272:1997;442-447.
37. Tikoo R., Osterhout D. J., Casaccia-Bonnefil P., Seth P., Koff A., Chao M. V. Ectopic expression of p27Kip1 in oligodendrocyte progenitor cells results in cell-cycle growth arrest. J. Neurobiol. 36:1998;431-440.
38. Turner D. L., Cepko C. L. A common progenitor for neurons and glia persists in rat retina late in development. Nature. 328:1987;131-136.
39. Turner D. L., Snyder E. Y., Cepko C. L. Lineage-independent determination of cell type in the embryonic mouse retina. Neuron. 4:1990;833-845.
40. van Lookeren Campagne M., Gill R. Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: Comparison with expression of the cell cycle regulators p21(Waf1/Cip1), p27(Kip1), p57(Kip2), p16(Ink4a), cyclin G1, and the proto-oncogene Bax. J. Comp. Neurol. 397:1998;181-198.
41. Watanabe G., Pena P., Shambaugh G. E. 3rd, Haines G. K. 3rd, Pestell R. G. Regulation of cyclin dependent kinase inhibitor proteins during neonatal cerebella development. Brain Res. Dev. Brain Res. 108:1998;77-87.
42. Wetts R., Fraser S. E. Multipotent precursors can give rise to all major cell types of the frog retina. Science. 239:1988;1142-1145.
43. Young R. W. Cell differentiation in the retina of the mouse. Anat. Rec. 212:1985a;199-205.
44. Young R. W. Cell proliferation during postnatal development of the retina in the mouse. Brain Res. 353:1985b;229-239.
45. Zhang P., Wong C., DePinho R. A., Harper J. W., Elledge S. J. Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development. Genes Dev. 12:1998;3162-3167.
46. Zhang P., Wong C., Liu D., Finegold M., Harper J. W., Elledge S. J. p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev. 13:1999;213-224.
47. Zuber M. E., Perron M., Philpott A., Bang A., Harris W. A. Giant eyes in Xenopus laevis by overexpression of XOptx2. Cell. 98:1999;341-352.