Drug delivery systems based on trimethyl lock lactonization: Poly(ethylene glycol) prodrugs of amino-containing compounds

Journal of Medicinal Chemistry

Volumn 43, Issue 3, 2000, Pages 475-487

  Greenwald, Richard B ^a   Choe, Yun H ^a   Conover, Charles D ^a   Shum, Kwok ^a   Wu, Dechun ^a   Royzen, Maksim ^a  

^a Enzon Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CARBAMIC ACID DERIVATIVE; CARBONIC ACID DERIVATIVE; CYTARABINE; DAUNORUBICIN; ESTER DERIVATIVE; MACROGOL; PRODRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OVARY TUMOR; STEREOSPECIFICITY;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DAUNORUBICIN; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; LACTONES; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; POLYETHYLENE GLYCOLS; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0034628515     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990498j     Document Type: Article

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