Coumarin-based prodrugs. Part 3: Structural effects on the release kinetics of esterase-sensitive prodrugs of amines

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 4, 1998, Pages 417-426

  Wang, Binghe ^a   Zhang, Huijuan ^a   Zheng, Ailian ^a   Wang, Wei ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Coumarin; Coumarinic acid; Esterase; Prodrug; Structural effect

Indexed keywords

COUMARIN DERIVATIVE; ESTERASE; PRODRUG;

ARTICLE; DRUG HALF LIFE; DRUG SYNTHESIS; HYDROLYSIS; STEREOSPECIFICITY;

AMINES; ANIMALS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; ESTERASES; HALF-LIFE; KINETICS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PHARMACEUTIC AIDS; PRODRUGS; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

SUIDAE;

EID: 0032053499     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00014-5     Document Type: Article

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