메뉴 건너뛰기




Volumn 40, Issue 3, 1996, Pages 209-223

Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model

Author keywords

Breast cancer; Fibronectin; Invasion; Mouse mammary tumor model; Protease inhibitors; Treatment; Urokinase

Indexed keywords

B 428; B 623; FIBRONECTIN; PLASMINOGEN ACTIVATOR INHIBITOR; UNCLASSIFIED DRUG; UROKINASE;

EID: 0029789744     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01806809     Document Type: Article
Times cited : (64)

References (48)
  • 1
    • 0021115222 scopus 로고
    • The role of proteinases in cellular invasiveness
    • Mullins DE, Rohrlich ST: The role of proteinases in cellular invasiveness. Biochim Biophys Acta 695: 177-214, 1983
    • (1983) Biochim Biophys Acta , vol.695 , pp. 177-214
    • Mullins, D.E.1    Rohrlich, S.T.2
  • 3
    • 0022969477 scopus 로고
    • Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade
    • Mignati P, Robbins E, Rifkin DB: Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade. Cell 47: 487-498, 1986
    • (1986) Cell , vol.47 , pp. 487-498
    • Mignati, P.1    Robbins, E.2    Rifkin, D.B.3
  • 4
    • 0023197175 scopus 로고
    • Urokinase-type plasminogen activator: Proenzyme, receptors and inhibitors
    • Blasi F, Vassalli J-D, Danø K: Urokinase-type plasminogen activator: proenzyme, receptors and inhibitors. J Cell Biol 104: 801-804, 1987
    • (1987) J Cell Biol , vol.104 , pp. 801-804
    • Blasi, F.1    Vassalli, J.-D.2    Danø, K.3
  • 5
    • 0024309860 scopus 로고
    • Growth factors in the regulation of pericellular proteolysis: A review
    • Laiho M, Keski-Oja J: Growth factors in the regulation of pericellular proteolysis: a review. Cancer Res 49: 2533-2553, 1989
    • (1989) Cancer Res , vol.49 , pp. 2533-2553
    • Laiho, M.1    Keski-Oja, J.2
  • 6
    • 0028767542 scopus 로고
    • Membrane proteases in focus
    • Vassali J-D, Pepper MS: Membrane proteases in focus. Nature 370: 14-15, 1994
    • (1994) Nature , vol.370 , pp. 14-15
    • Vassali, J.-D.1    Pepper, M.S.2
  • 7
    • 0027394284 scopus 로고
    • Structure and function of the urokinase receptor
    • Møller LB: Structure and function of the urokinase receptor. Blood Coagul Fibrinol 4: 293-303, 1993
    • (1993) Blood Coagul Fibrinol , vol.4 , pp. 293-303
    • Møller, L.B.1
  • 8
    • 0021045628 scopus 로고
    • Antibodies to plasminogen activator inhibit human tumor metastasis
    • Ossowski L, Reich E: Antibodies to plasminogen activator inhibit human tumor metastasis. Cell 35: 611-619, 1983
    • (1983) Cell , vol.35 , pp. 611-619
    • Ossowski, L.1    Reich, E.2
  • 9
    • 0023853553 scopus 로고
    • Plasminogen activator dependent pathway in the dissemination of human tumor cells in the chick embryo
    • Ossowski L: Plasminogen activator dependent pathway in the dissemination of human tumor cells in the chick embryo. Cell 52:321-328, 1988
    • (1988) Cell , vol.52 , pp. 321-328
    • Ossowski, L.1
  • 10
    • 0025968060 scopus 로고
    • Inhibition of urokinase-type plasminogen activator by antibodies: The effect on dissemination of a human tumor in the nude mouse
    • Ossowski L, Russo-Payne H, Wilson EL: Inhibition of urokinase-type plasminogen activator by antibodies: the effect on dissemination of a human tumor in the nude mouse. Cancer Res 51: 274-281, 1991
    • (1991) Cancer Res , vol.51 , pp. 274-281
    • Ossowski, L.1    Russo-Payne, H.2    Wilson, E.L.3
  • 11
    • 0023576670 scopus 로고
    • Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells
    • Pepper MS, Vassalli J-D, Montesano R, Orci L: Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells. J Cell Biol 105: 2535-2541, 1987
    • (1987) J Cell Biol , vol.105 , pp. 2535-2541
    • Pepper, M.S.1    Vassalli, J.-D.2    Montesano, R.3    Orci, L.4
  • 12
    • 0023646314 scopus 로고
    • Amiloride selectively inhibits the urokinase-type plasminogen activator
    • Vassalli J-D, Bellin D: Amiloride selectively inhibits the urokinase-type plasminogen activator. FEBS Lett 214: 187-191, 1987
    • (1987) FEBS Lett , vol.214 , pp. 187-191
    • Vassalli, J.-D.1    Bellin, D.2
  • 13
    • 0027314501 scopus 로고
    • Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: An important new class of selective synthetic urokinase inhibitor
    • Towle MJ, Lee A, Maduakor EC, Schwartz EC, Bridges AJ, Littlefield BA: Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitor. Cancer Res 53: 2553-2559, 1993
    • (1993) Cancer Res , vol.53 , pp. 2553-2559
    • Towle, M.J.1    Lee, A.2    Maduakor, E.C.3    Schwartz, E.C.4    Bridges, A.J.5    Littlefield, B.A.6
  • 14
    • 10144239532 scopus 로고
    • In vitro and in vivo effects of potassium-sparing diuretics in a urokinase-producing murine mammary adenocarcinoma model
    • Abstract
    • Alonso DF, Farías EF, Puricelli L, Bal de Kier Joffé E: In vitro and in vivo effects of potassium-sparing diuretics in a urokinase-producing murine mammary adenocarcinoma model. Proc Am Assoc Cancer Res 35: 68, 1994 (Abstract)
    • (1994) Proc Am Assoc Cancer Res , vol.35 , pp. 68
    • Alonso, D.F.1    Farías, E.F.2    Puricelli, L.3    Bal De Kier Joffé, E.4
  • 15
    • 0023016556 scopus 로고
    • Modified adhesion behavior after in vitro passage of two related murine mammary adenocarcinomas with different metastatic ability
    • Bal de Kier Joffé E, Puricelli L, Sacerdote de Lustig E: Modified adhesion behavior after in vitro passage of two related murine mammary adenocarcinomas with different metastatic ability. Invasion Metastasis 6: 302-312, 1986
    • (1986) Invasion Metastasis , vol.6 , pp. 302-312
    • Bal De Kier Joffé, E.1    Puricelli, L.2    Sacerdote De Lustig, E.3
  • 16
    • 0028650349 scopus 로고
    • Urokinase-type plasminogen activator activity released by clonal tumor cell populations isolated during the growth of a murine mammary adenocarcinoma
    • Alonso DF, Farías EF, Bal de Kier Joffé E: Urokinase-type plasminogen activator activity released by clonal tumor cell populations isolated during the growth of a murine mammary adenocarcinoma. J Exp Clin Cancer Res 13: 211-216, 1994
    • (1994) J Exp Clin Cancer Res , vol.13 , pp. 211-216
    • Alonso, D.F.1    Farías, E.F.2    Bal De Kier Joffé, E.3
  • 18
    • 0026564455 scopus 로고
    • Urokinase-type plasminogen activator activity increases during the growth of two murine mammary adenocarcinomas with different metastasizing abilities
    • Pereyra-Alfonso S, Solarz GR, Bal de Kier Joffé E: Urokinase-type plasminogen activator activity increases during the growth of two murine mammary adenocarcinomas with different metastasizing abilities. Clin Exp Metastasis 10: 395-401, 1992
    • (1992) Clin Exp Metastasis , vol.10 , pp. 395-401
    • Pereyra-Alfonso, S.1    Solarz, G.R.2    Bal De Kier Joffé, E.3
  • 19
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli U: Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.1
  • 20
    • 0027237171 scopus 로고
    • Impairment of fibrinolysis during the growth of two murine mammary adenocarcinomas
    • Alonso DF, Farías EF, Bal de Kier Joffé E: Impairment of fibrinolysis during the growth of two murine mammary adenocarcinomas. Cancer Lett 70: 181-187, 1993
    • (1993) Cancer Lett , vol.70 , pp. 181-187
    • Alonso, D.F.1    Farías, E.F.2    Bal De Kier Joffé, E.3
  • 21
    • 0020064684 scopus 로고
    • Isolation and characterization of urokinase from human plasma
    • Wun TC, Schleuning WD, Reich E: Isolation and characterization of urokinase from human plasma. J Biol Chem 257: 3276-3283, 1982
    • (1982) J Biol Chem , vol.257 , pp. 3276-3283
    • Wun, T.C.1    Schleuning, W.D.2    Reich, E.3
  • 22
    • 0019450328 scopus 로고
    • Radial caseinolysis in agarose: A simple method for detection of plasminogen activator in the presence of inhibitory substances and serum
    • Saksela O: Radial caseinolysis in agarose: a simple method for detection of plasminogen activator in the presence of inhibitory substances and serum. Anal Biochem 111: 276-282, 1981
    • (1981) Anal Biochem , vol.111 , pp. 276-282
    • Saksela, O.1
  • 23
    • 0025844741 scopus 로고
    • Malignant transformation of human fibroblast correlates with increased activity of receptor-bound plasminogen activator
    • Jankum, J Maher VM, McCormick JJ: Malignant transformation of human fibroblast correlates with increased activity of receptor-bound plasminogen activator. Cancer Res 51: 1221-1226, 1991
    • (1991) Cancer Res , vol.51 , pp. 1221-1226
    • Jankum, J.1    Maher, V.M.2    McCormick, J.J.3
  • 24
    • 0027477597 scopus 로고
    • Therapeutic potential of analogues of amiloride: Inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy
    • Maidorn RP, Cragoe EJ Jr, Tannock IF: Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy. Br J Cancer 67: 297-303, 1993
    • (1993) Br J Cancer , vol.67 , pp. 297-303
    • Maidorn, R.P.1    Cragoe Jr., E.J.2    Tannock, I.F.3
  • 26
    • 0017188133 scopus 로고
    • Lymphocyte-induced angiogenesis in tumor-bearing mice
    • Sidky YA, Auerbach R: Lymphocyte-induced angiogenesis in tumor-bearing mice. Science 192: 1237-1238, 1976
    • (1976) Science , vol.192 , pp. 1237-1238
    • Sidky, Y.A.1    Auerbach, R.2
  • 27
    • 0022988714 scopus 로고
    • Lymphocyte-induced angiogenesis: Correlation with the metastatic incidence of two murine mammary adenocarcinomas
    • Miguez M, Davel L, Sacerdote de Lustig E: Lymphocyte-induced angiogenesis: correlation with the metastatic incidence of two murine mammary adenocarcinomas. Invasion Metastasis 6: 313-320, 1986
    • (1986) Invasion Metastasis , vol.6 , pp. 313-320
    • Miguez, M.1    Davel, L.2    Sacerdote De Lustig, E.3
  • 28
    • 0027941545 scopus 로고
    • Inhibition of lymphocyte-induced angiogenesis by free radical scavengers
    • Monte M, Davel L, Sacerdote de Lustig E: Inhibition of lymphocyte-induced angiogenesis by free radical scavengers. Free Radic Biol Med 17: 259-266, 1994
    • (1994) Free Radic Biol Med , vol.17 , pp. 259-266
    • Monte, M.1    Davel, L.2    Sacerdote De Lustig, E.3
  • 29
    • 0041007377 scopus 로고
    • Correlation between urokinase-type plasminogen activator production and the metastasizing ability of two murine mammary adenocarcinomas
    • Pereyra-Alfonso S, Haedo A, Bal de Kier Joffé E: Correlation between urokinase-type plasminogen activator production and the metastasizing ability of two murine mammary adenocarcinomas. Int J Cancer 42: 59-63, 1988
    • (1988) Int J Cancer , vol.42 , pp. 59-63
    • Pereyra-Alfonso, S.1    Haedo, A.2    Bal De Kier Joffé, E.3
  • 30
    • 0024238269 scopus 로고
    • In vivo invasion of modified chorioallantoic membrane by tumor cells: The role of cell suface-bound urokinase
    • Ossowski L: In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell suface-bound urokinase. J Cell Biol 107: 2437-2445, 1988
    • (1988) J Cell Biol , vol.107 , pp. 2437-2445
    • Ossowski, L.1
  • 31
    • 0025942415 scopus 로고
    • Involvement of urokinase and its receptor in the invasiveness of human prostatic carcinoma carcinoma cell lines
    • Hoosein NM, Boyd DD, Hollas WJ, Mazar A, Henkin J, Chung LW: Involvement of urokinase and its receptor in the invasiveness of human prostatic carcinoma carcinoma cell lines. Cancer Commun 3: 255-264, 1991
    • (1991) Cancer Commun , vol.3 , pp. 255-264
    • Hoosein, N.M.1    Boyd, D.D.2    Hollas, W.J.3    Mazar, A.4    Henkin, J.5    Chung, L.W.6
  • 32
    • 0026734254 scopus 로고
    • Inhibition of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B
    • Kobayashi H, Ohi H, Sugimura M, Shinohara H, Fujii T, Terao T: Inhibition of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B. Cancer Res 52: 3610-3614, 1992
    • (1992) Cancer Res , vol.52 , pp. 3610-3614
    • Kobayashi, H.1    Ohi, H.2    Sugimura, M.3    Shinohara, H.4    Fujii, T.5    Terao, T.6
  • 33
    • 0026690822 scopus 로고
    • Endogenous receptor-bound urokinase mediates tissue invasion of the lung carcinoma cell lines A549 and Calu-1
    • Bruckner A, Filderman AE, Kirchheimer JC, Binder BR, Remold HG: Endogenous receptor-bound urokinase mediates tissue invasion of the lung carcinoma cell lines A549 and Calu-1. Cancer Res 52: 3043-3047, 1992
    • (1992) Cancer Res , vol.52 , pp. 3043-3047
    • Bruckner, A.1    Filderman, A.E.2    Kirchheimer, J.C.3    Binder, B.R.4    Remold, H.G.5
  • 34
    • 0010469194 scopus 로고
    • Limited cleavage of cellular fibronectin by plasminogen activator purified from transformed cells
    • Quigley JP, Gold LI, Schwimmer R, Sullivan LM: Limited cleavage of cellular fibronectin by plasminogen activator purified from transformed cells. Proc Natl Acad Sci USA 84: 2776-2780, 1987
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2776-2780
    • Quigley, J.P.1    Gold, L.I.2    Schwimmer, R.3    Sullivan, L.M.4
  • 35
    • 0026727189 scopus 로고
    • Localization of the cleavage sites on fibronectin following digestion by urokinase
    • Gold LI, Rostagno A, Frangione B, Passalaris T: Localization of the cleavage sites on fibronectin following digestion by urokinase. J Cell Biochem 50: 441-452, 1992
    • (1992) J Cell Biochem , vol.50 , pp. 441-452
    • Gold, L.I.1    Rostagno, A.2    Frangione, B.3    Passalaris, T.4
  • 36
    • 0025231264 scopus 로고
    • Better reception for urokinase
    • Mangel WF: Better reception for urokinase. Nature 344: 488-489, 1990
    • (1990) Nature , vol.344 , pp. 488-489
    • Mangel, W.F.1
  • 37
    • 0027157426 scopus 로고
    • Indispensable role of tissue-type plasminogen activator in growth factor-dependent tube formation of human microvascular endothelial cells in vitro
    • Sato Y, Okamura K, Morimoto A, Hamanaka R, Hamaguchi K, Shimada T, Ono M, Kohno K, Sakata T, Kuwano M: Indispensable role of tissue-type plasminogen activator in growth factor-dependent tube formation of human microvascular endothelial cells in vitro. Exp Cell Res 204: 223-229, 1993
    • (1993) Exp Cell Res , vol.204 , pp. 223-229
    • Sato, Y.1    Okamura, K.2    Morimoto, A.3    Hamanaka, R.4    Hamaguchi, K.5    Shimada, T.6    Ono, M.7    Kohno, K.8    Sakata, T.9    Kuwano, M.10
  • 38
    • 0030025931 scopus 로고    scopus 로고
    • Antimetastatic effects associated with anticoagulant properties of heparin and chemically modified heparin species in a mouse mammary tumor model
    • Alonso DF, Bertolesi GE, Farías EF, Eiján AM, Bal de Kier Joffé E, Lauría de Cidre L: Antimetastatic effects associated with anticoagulant properties of heparin and chemically modified heparin species in a mouse mammary tumor model. Oncology Rep 3: 219-222, 1996
    • (1996) Oncology Rep , vol.3 , pp. 219-222
    • Alonso, D.F.1    Bertolesi, G.E.2    Farías, E.F.3    Eiján, A.M.4    Bal De Kier Joffé, E.5    Lauría De Cidre, L.6
  • 40
    • 0023610220 scopus 로고
    • Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing
    • Dvorak HF, Harvey VS, Estrella P, Brown LF, McDonagh J, Dvorak AM: Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing. Lab Invest 57: 673-686, 1987
    • (1987) Lab Invest , vol.57 , pp. 673-686
    • Dvorak, H.F.1    Harvey, V.S.2    Estrella, P.3    Brown, L.F.4    McDonagh, J.5    Dvorak, A.M.6
  • 43
    • 0024202197 scopus 로고
    • Antimetastatic effect of amiloride in an animal tumor model
    • Kellen JA, Mirakian JA, Kolin A: Antimetastatic effect of amiloride in an animal tumor model. Anticancer Res 8: 1373-1376, 1988
    • (1988) Anticancer Res , vol.8 , pp. 1373-1376
    • Kellen, J.A.1    Mirakian, J.A.2    Kolin, A.3
  • 44
    • 0023010810 scopus 로고
    • Relationship between circulating plasminogen activators and tumor development in mice
    • Colombi M, Rebessi L, Boiocchi M, Barlati S: Relationship between circulating plasminogen activators and tumor development in mice. Cancer Res 46: 5748-5753, 1986
    • (1986) Cancer Res , vol.46 , pp. 5748-5753
    • Colombi, M.1    Rebessi, L.2    Boiocchi, M.3    Barlati, S.4
  • 45
    • 0023720810 scopus 로고
    • Role of fibrin coagulation in protection of murine tumor cells from destruction by cytotoxic cells
    • Gunji Y, Gorelik E: Role of fibrin coagulation in protection of murine tumor cells from destruction by cytotoxic cells. Cancer Res 48: 5216-5221, 1988
    • (1988) Cancer Res , vol.48 , pp. 5216-5221
    • Gunji, Y.1    Gorelik, E.2
  • 46
    • 0025938196 scopus 로고
    • Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor
    • Esumi N, Fan D, Fidler IJ: Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor. Cancer Res 51: 4549-4556, 1991
    • (1991) Cancer Res , vol.51 , pp. 4549-4556
    • Esumi, N.1    Fan, D.2    Fidler, I.J.3
  • 47
    • 0024508761 scopus 로고
    • Plasminogen activator in dextran sulfate-activated euglobulin-fractions: A molecular analysis of factor XII- and prekallikrein-dependent fibrinolysis
    • Hauert J, Nicoloso G, Schleuning W, Bachmann F, Schapira M: Plasminogen activator in dextran sulfate-activated euglobulin-fractions: a molecular analysis of factor XII- and prekallikrein-dependent fibrinolysis. Blood 4:994-999, 1989
    • (1989) Blood , vol.4 , pp. 994-999
    • Hauert, J.1    Nicoloso, G.2    Schleuning, W.3    Bachmann, F.4    Schapira, M.5
  • 48
    • 0028944106 scopus 로고
    • Molecular insights into cancer invasion: Strategies for prevention and intervention
    • Kohn EC, Liotta LA: Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res 55: 1856-1862, 1995
    • (1995) Cancer Res , vol.55 , pp. 1856-1862
    • Kohn, E.C.1    Liotta, L.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.