The role of DNA amplification technology in the diagnosis of infectious diseases

CMAJ. Canadian Medical Association Journal

Volumn 163, Issue 3, 2000, Pages 301-309

  Louie, M ^a   Louie, L ^a   Simor, A E ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; BETA LACTAM ANTIBIOTIC; CEFACLOR; CEPHALOSPORIN DERIVATIVE; GANCICLOVIR; ISONIAZID; METICILLIN; PENICILLIN G; PROTEINASE INHIBITOR; RIFAMPICIN; RNA DIRECTED DNA POLYMERASE INHIBITOR; VANCOMYCIN;

ADULT; ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; CASE REPORT; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC VALUE; FEMALE; GENE AMPLIFICATION; HUMAN; MALE; MYCOBACTERIOSIS; NUCLEIC ACID ANALYSIS; POLYMERASE CHAIN REACTION; REVIEW; VIRUS INFECTION; VIRUS LOAD;

EID: 0034622467     PISSN: 08203946     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (81)

1. Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
2. Application of polymerase chain reactions to the diagnosis of infectious diseases
3. DNA probe amplification methods
4. Molecular diagnostics of infectious diseases
5. Molecular pathology diagnosis of infectious disease
6. Laboratory diagnosis of pertussis: State of the art in 1997
7. Diagnostic value of PCR for detection of Borrelia burgdorferi in skin biopsy and urine samples from patients with skin borreliosis
8. Cblamydia pneumoniae pneumonia in hospitalized patients. Clinical characteristics and diagnostic value of polymerase chain reaction detection in BAL
9. Multicenter evaluation of the fully automated COBAS AMPLICOR PCR Test for detection of Chlamydia trachomatis in urogenital specimens
10. Comparison of manual Amplicor PCR, Cobas Amplicor PCR, and LCx assays for detection of Chlamydia trachomatis infection in women by using urine specimens
11. Comparison of performances of two commercially available tests, a PCR assay and a ligase chain reaction test, in detection of urogenital Chlamydia trachomatis infection
12. Diagnosis of Chlamydia trachomatis infections in asymptomatic men and women by PCR assay
13. Application of multiplex PCR for detection of non-O157 verocytotoxin-producing Escherichia coli in bloody stools: Identification of serogroups O26 and O111
14. Comparative evaluation of two commercial amplification assays for direct detection of Mycobacterium tuberculosis complex in respiratory specimens
15. Rapid diagnosis of pulmonary tuberculosis by using Roche AMPLICOR Mycobacterium tuberculosis PCR test
16. Use of PCR in detection of Mycobacterium avium complex (MAC) bacteremia: Sensitivity of the assay and effect of treatment for MAC infectlon on concentrations of human immunodeficiency virus in plasma
17. Detection of Mycoplasma pneumoniae and Mycoplasma genitalium in clinical samples by polymerase chain reaction
18. Comparison of polymcrase chain reaction assay with culture for detection of genital mycoplasmas in perinatal infections
19. Detection of Neisseria gonorrhoeae and Chlamydia trachomatis in genitourinary specimens from men and women by a coamplification PCR assay
20. Direct multiplex PCR for the rapid detection of bacterial pathogens associated with acute meningitis
21. PCR-enzyme immunoassay for detection of Streptococcus pneumoniae DNA in cerebrospinal fluid samples from patients with culture-negative meningitis
22. Rapid PCR-based detection of Streptococcus pneumoniae DNA in cerebrospinal fluid
23. Diagnosis of group A streptococcal necrotizing fasciitis by using PCR to amplify the streptococcal pyrogenic exotoxin B gene
24. Detection of cytomegalovirus in plasma and cerebrospinal fluid specimens from human immunodeficiency virus-infected patients by the AMPLICOR CMV Test
25. Evaluation of new quantitative assays for diagnosis and monitoring of cytomegalo-virus disease in human immunodeficiency virus-positive patients
26. Multicenter evaluation of the Amplicor Enterovirus PCR Test with cerebrospinal fluid from patients with aseptic meningitis
27. Amplicor Enterovirus polymerase chain reaction in patients with aseptic meningitis. A sensitive test limited by amplification inhibitors
28. What technique should be used for routine detection and quantification of HBV DNA in clinical samples?
29. Multicenter evaluation of the COBAS AMPLICOR HCV assay, an integrated PCR system for rapid detection of hepatitis C virus RNA in the diagnostic laboratory
30. Diagnosis of herpes simplex eneephalitis Application of polymerase chain reaction to cerebrospinal fluid from brain-binpsied patients and correlation with disease
31. Clinical comparison of an enhanced-sensitivity branched-DNA assay and reverse transcription-PCR for quantitation of human immunodeficiency virus type-1 RNA in plasma
32. Rapid and precise quantification of HIV-1 RNA in plasma using a branched DNA signal amplification assay
33. Comparison of the QUANTIPLEX HIV-1 RNA 2.0 Assay with the AMPLICOR HIV-1 MONITOR 1.0 Assay for quantitation of levels of human immunodeficiency virus type 1 RNA in plasma of patients receiving stavudine-didanosine combination therapy
34. Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species
35. Evaluation of a colorimetric PCR-based assay to diagnose Plasmodium falciparum malaria in travelers
36. Diagnostic use of PCR for detection of Pneumocystis carinii in oral wash samples
37. Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by the polymerase chain reaction
38. Diagnosis of Trichomonas vaginalis infection by PCR using vaginal swab samples
39. Current methods of laboratory diagnosis of Chlamydia trachomatis infections
40. Multicenter evaluation of the Abbott Lcx Mycobacterium tuberculosis ligase chain reaction assay
41. Prospective clinical evaluation of Amplicor Mycobacterium tuberculosis PCR test as a screening method in a low-prevalence population
42. Utility of PCR in diagnosing pulmonary tuberculosis
43. Herpes simplex virus infections of the central nervous system: Therapeutic and diagnostic considerations
44. Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection
45. Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response
46. Direct detection of respiratory syncytial virus, parainfluenza virus, and adenovirus in clinical respiratory specimens by a multiplex reverse transcription-PCR assay
47. Simultaneous detection and identification of human parainfluenza viruses 1, 2, and 3 from clinical samples by multiplex PCR
48. Rapid identification of nine microorganisms causing acute respiratory tract infections by single-tube multiplex reverse transcription-PCR: Feasibility study
49. Value of the polymerase chain reaction assay in noninvasive respiratory samples for diagnosis of community-acquired pneumonia
50. Detection of Haemophilus influenzae and Streptococcus pneumoniae DNA in blood culture by a single PCR assay
51. Detection of bacteraemia in patients with fever and neutropenia using 16S rRNA gene amplification by polymerase chain reaction
52. Diagnosis of viral infections of the central nervous system
53. Aseptic meningitis and encephalitis: The role of PCR in the diagnostic laboratory
54. Identification of the uncultured bacillus of Whipple's Disease
55. The agent of bacillary angiomatosis: An approach to the identification of uncultured pathogens
56. Isolation of Chlamydia pneumoniae from the coronary artery of a patient with coronary atherosclerosis
57. Genetic methods for assessing antimicrobial resistance
58. Rapid and specific molecular identification of methicillin-resistant Staphylococcus aureus in endotracheal aspirates from mechanically ventilated patients
59. Identification of methicillin-resistant strains of staphylococci by polymerase chain reaction
60. Detection of vancomycin-resistant enterococci in fecal samples by PCR
61. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR
62. Multiplex PCR detection of vanA, vanB, vanC-1, and vanC-2/3 genes in enterococci
63. Application of pbp1A PCR in identification of penicillin-resistant Streptococcus pneumoniae
64. Molecular characterisation by PCR-restriction fragment length polymorphism of TEM β-lactamases
65. Detection of resistance to isoniazid, rifampin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods
66. Direct, automated detection of rifampin-resistant Mycobacteriurn tuberculosis by polymerase chain reaction and single-stranded conformation polymorphism analysis
67. Homopolymer mutational hot spots mediate herpes simplex virus resistance to acyclovir
68. High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes
69. Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type I reverse transcriptase gene
70. Emergence of protease inhibitor resistance mutations in human immunodeficiency virus type 1 isolates from patients and rapid screening procedure for their detection
71. Evaluation of laboratory tests for detection of methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis
72. Detection of the mec-A gene and phenotypic detection of resistance in Staphylococcus aureus isolates with borderline or low-level methicillin resistance
73. Detection of methicillin-resistant Staphylococcus aureus (MRSA) from growth on mannitol salt oxacillin agar using PCR for nosocomial surveillance
74. Rapid diagnosis of methicillin-resistant Staphylococcus aureus bacteremia by nested polymerase chain reaction
75. Are clinical laboratories in California accurately reporting vancomycin-resistant enterococci?
76. Should genotypic testing be done on all phenotypically vancomycin-resistant enterococci detected in hospitals?
77. Evaluation of a vanA-specific assay for detection of vancomycin-resistant Enterococcus faecium during a hospital outbreak
78. Molecular diagnosis of bacterial endocarditis by broad-range PCR amplification and direct sequecing
79. Gram type-specific broad-range PCR amplification for rapid detection of 62 pathogenic bacteria
80. Polymerase chain reaction for assessing treatment response in patients with pulmonary tuberculosis
81. Prospective study to determine clinical relevance of detection of pneumococcal DNA in sera of children by PCR