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Volumn 176, Issue 1, 1997, Pages 69-77

High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes

Author keywords

[No Author keywords available]

Indexed keywords

CIDOFOVIR; DNA POLYMERASE; FOSCARNET; GANCICLOVIR; GANCICLOVIR CYCLIC PHOSPHATE; PHOSPHOTRANSFERASE;

EID: 0030991256     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/514041     Document Type: Article
Times cited : (246)

References (10)
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    • Progressive disease due to ganciclovir-resistant Cytomegalovirus in immunocompromised patients
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    • Foscarnet therapy for ganciclovir-resistant patients with AIDS
    • Jacobsen MA, Drew WL, Feinberg J, et al. Foscarnet therapy for ganciclovir-resistant patients with AIDS. J Infect Dis 1991;163:1348-51.
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    • Jacobsen, M.A.1    Drew, W.L.2    Feinberg, J.3
  • 6
    • 16944365542 scopus 로고
    • Reduced Cytomegalovirus susceptibility to foscarnet is found in ganciclovir resistant isolates and foscarnet resistance is conferred by mutations in the CMV polymerase
    • San Francisco. Washington, DC: American Society for Microbiology
    • Smith IL, Jiles RE, Spector SA. Reduced Cytomegalovirus susceptibility to foscarnet is found in ganciclovir resistant isolates and foscarnet resistance is conferred by mutations in the CMV polymerase [abstract]. In: Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy (San Francisco). Washington, DC: American Society for Microbiology, 1995.
    • (1995) Program and Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Smith, I.L.1    Jiles, R.E.2    Spector, S.A.3
  • 7
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    • Double resistance to ganciclovir and foscarnet of four human Cytomegalovirus strains recovered from AIDS patients
    • Sarasini A, Baldanti F, Furione M, et al. Double resistance to ganciclovir and foscarnet of four human Cytomegalovirus strains recovered from AIDS patients. J Med Virol 1995;47:237-44.
    • (1995) J Med Virol , vol.47 , pp. 237-244
    • Sarasini, A.1    Baldanti, F.2    Furione, M.3
  • 8
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    • Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double resistant human Cytomegalovirus strains recovered from patients with AIDS
    • Baldanti F, Underwood MR, Stanat SC, et al. Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double resistant human Cytomegalovirus strains recovered from patients with AIDS. J Virol 1996;70:1390-5.
    • (1996) J Virol , vol.70 , pp. 1390-1395
    • Baldanti, F.1    Underwood, M.R.2    Stanat, S.C.3
  • 9
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    • A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human Cytomegalovirus clinical isolate
    • Baldanti F, Silini E, Sarasini A, et al. A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human Cytomegalovirus clinical isolate. J Virol 1995;69:796-800.
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    • Baldanti, F.1    Silini, E.2    Sarasini, A.3
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    • Monitoring of ganciclovir sensitivity of multiple human Cytomegalovirus strains coinfecting blood of an AIDS patient by an immediate-early antigen plaque assay
    • Gerna G, Baldanti F, Zavattoni M, Sarasini A, Percivalle E, Revello MG. Monitoring of ganciclovir sensitivity of multiple human Cytomegalovirus strains coinfecting blood of an AIDS patient by an immediate-early antigen plaque assay. Antiviral Res 1992;19:333-45.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.