Synthesis and preliminary biological evaluation of [3H]-MRE 3008-F20: The first high affinity radioligand antagonist for the human A3 adenosine receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 3, 2000, Pages 209-211

  Baraldi, Pier Giovanni ^a   Cacciari, Barbara ^a   Romagnoli, Romeo ^a   Varani, Katia ^a   Merighi, Stefania ^a   Gessi, Stefania ^a   Borea, Pier Andrea ^a   Leung, Edward ^b   Hickey, Sarah L ^c   Spalluto, Giampiero ^d  

^a UNIVERSITY OF FERRARA   (Italy)

^b Medco Research Inc   (United States)

^c GENERAL ELECTRIC COMPANY   (United States)

^d UNIVERSITY OF TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 FURYL) 5 [3 (4 METHOXYPHENYL)UREIDO] 8 PROPYLPYRAZOLO[4,3 E] 1,2,4 TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; RADIOLIGAND; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHO CELL; DRUG BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; NONHUMAN; REACTION ANALYSIS;

ANIMALS; CHO CELLS; CRICETINAE; HUMANS; PHENYLUREA COMPOUNDS; RADIOLIGAND ASSAY; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; RECOMBINANT PROTEINS; TRIAZOLES; TRITIUM;

ANIMALIA; TRITIUM;

EID: 0034615180     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00674-5     Document Type: Article

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