Differential expression of CD28 and CD94/NKG2 on T cells with identical TCR beta variable regions in primary melanoma and sentinel lymph node

European Journal of Immunology

Volumn 30, Issue 12, 2000, Pages 3699-3706

  Becker, Jrgen C ^a   Vetter, Claudia S ^b   Schrama, David ^b   Brcker, Eva B ^b   Straten, Per Thor ^a  

^a Department of Dermatology   (Germany)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Melanoma; NK receptor; T lymphocyte

Indexed keywords

CD28 ANTIGEN; CD94 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CELL CLONE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOLYSIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPATHOLOGY; IMMUNOREACTIVITY; LYMPHOCYTE ACTIVATION; MELANOMA; NATURAL KILLER CELL; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SENTINEL LYMPH NODE; T LYMPHOCYTE;

ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD94; HUMANS; IMMUNOPHENOTYPING; LECTINS, C-TYPE; LYMPH NODES; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA; MEMBRANE GLYCOPROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES;

EID: 0034535521     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200012)30:12<3699::AID-IMMU3699>3.0.CO;2-2     Document Type: Article

References (45)

1. The instructive role of innate immunity in the acquired immune response
2. Paired inhibitory triggering NK cell receptors for HLA class I molecules
3. Leukocyte-associated Ig-like receptor-1 functions as an inhibitory receptor on cytotoxic T cells
4. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
5. HLA-class I-specific inhibitory receptors in human cytolytic T lymphocytes: Molecular characterization distribution in lymphoid tissues and co-expression by individual T cells
6. Stimulatory receptors in NK and T cells
7. The enigma of activating isoforms of ITIM-bearing molecules
8. Association of DAP12 with activating CD94/NKG2C NK cell receptors
9. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
10. NK cell activation: Distinct stimulatory pathways counterbalancing inhibitory signals
11. + T cells in primary and secondary influenza pneumonia
12. In situ T cells in melanoma
13. Expression of CD94/NKG2 subtypes on tumor-infiltrating iymphocytes in primary and metastatic melanoma
14. Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor
15. In search of the 'missing self': MHC molecules and NK cell recognition
16. Regulation of KIR expression in human T cells: A safety mechanism that may impair protective T-cell responses
17. + T cells
18. + T cells contain greatly expanded functional virus-specific memory CTL clones
19. CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients
20. Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence
21. Immunohistochemical analysis of the T-cell receptor beta-chain variable regions expressed by T lymphocytes infiltrating primary human melanoma
22. Detection and characterization of alpha-beta-T-cell clonality by denaturing gradient gel electrophoresis (DGGE)
23. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
24. Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes
25. In vivo detection of dendritic cell antigen presentation to CD4(+) T cells
26. Fibroblasts as efficient antigen-presenting cells in lymphoid organs
27. In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes
28. Antitumor immunity at work in a melanoma patient
29. + T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations
30. + CD28- cytotoxic effector clones
31. - T cells in HIV-1-infected patients
32. + T cell subset: Age-associated expansion and shift from memory to naive phenotype
33. T-cell clonality in immune responses
34. C-type lectin-like receptors in peptide-specific HLA class I-restricted cytotoxic T lymphocytes: Differential expression and modulation of effector functions in clones sharing identical TCR structure and epitope specificity
35. The immunologic properties of melanoma-associated antigens recognized by cytotoxic T lymphocytes
36. Accumulation of identical T cells in melanoma and vitiligo-like leukoderma
37. + T cells with enhanced functional characteristics: Implication for more effective immunotherapy
38. Interleukin-15-induced maturation of human natural killer cells from early thymic precursors: Selective expression of CD94/NKG2-A as the only HLA class I-specific inhibitory receptor
39. Dendritic cell secretion of IL-15 is induced by recombinant huCD40LT and augments the stimulation of antigen-specific cytolytic T cells
40. IL-15 is produced by a subset of human melanomas and is involved in the regulation of markers of melanoma progression through juxtacrine loops
41. Transforming growth factor-beta-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes
42. + T cells is controlled by T-cell receptor engagement
43. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
44. Tolerance, danger and the extended family
45. Multi-institutional melanoma lymphatic mapping experience: The prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients