Generation of CD28- cells from long-term-stimulated CD8+CD28+ T cells: A possible mechanism accounting for the increased number of CD8+CD28- T cells in HIV-1-infected patients

Journal of Leukocyte Biology

Volumn 65, Issue 5, 1999, Pages 641-648

  Fiorentini, Simona ^a   Malacarne, Fabio ^a   Ricotta, Doris ^a   Licenziati, Stefano ^a   Soils, Adakatia Armenia ^a   Ausenda, Sabrina ^a   De Francesco, Maria ^a   Garrafa, Emirena ^a   Simonini, Andrea ^a   Imberti, Luisa ^b   Balsari, Andrea ^c   Turano, Adolfo ^a   Caruso, Arnaldo ^a  

^a Brescia Medical School   (Italy)

^b Third Laboratory   (Italy)

^c NONE

Author keywords

Cellular differentiation; Clonal expansion; Cytokines

Indexed keywords

CD28 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2;

ANTIGENICITY; ARTICLE; BLOOD SAMPLING; CELL DIFFERENTIATION; CELL PROLIFERATION; DENDRITIC CELL; DISULFIDE BOND; EFFECTOR CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MULTIGENE FAMILY; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0032942439     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.65.5.641     Document Type: Article

References (38)

1. Hansen, J. A., Martin, P. J., Nowinski, R. C. (1980) Monoclonal antibodies identifying a novel T cell antigen and Ia antigens of human lymphocytes. Immunogenetics 10, 247-260.
2. Hara, T. S., Fu, M., Hansen, J. A. (1985) Human T cell activation II. A new activation pathway used by a minor T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J. Exp. Med. 161, 1513-1524.
3. Freedman, A. S., Freeman, G. J., Horowitz, J. C., Daley, J., Nadler, L. M. (1987) B7, a B cell-restricted antigen that identifies preactivated B cells. J. Immunol. 139, 3260-3267.
4. Freeman, G. J., Freedman, A. S., Segil, J. M., Lee, G., Whitman, J. F., Nadler, L. M. (1989) B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143, 2714-2722.
5. Fraser, J. D., Irving, B. A., Crabtree, G. R., Weiss, A. (1991) Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science 251, 313-316.
6. Thompson, C. B., Lindsten, T., Ledbetter, J. A., Kunkel, S. L., Young, H. A., Emerson, S. G., Leiden, J. M., June, C. H. (1989) CD28 activation pathway regulates the production of multiple T cell derived lymphokines/ cytokines. Proc. Natl. Acad. Sci. USA 86, 1333-1337.
7. Lindsten, T., June, C. H., Ledbetter, J. A., Stella, G., Thompson, C. B. (1989) Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 244, 339-343.
8. Yamada, H., Martin, P. J., Braun, M. P., Beatty, P. G., Sadamoto, K., Hansen, J. A. (1985) Monoclonal antibody 9.3 and anti-CD11 antibodies define reciprocal subsets of lymphocytes. Eur. J. Immunol. 15, 1164-1168.
9. + lymphocytes during HIV infection. Scand. J. Immunol. 40, 485-490.
10. Brinchmann, J. E., Doblough, J. H., Heger, B. H., Haaheim, L. L., Sannes, M., Egeland, T. (1994) Expression of costimulatory molecule CD28 on T cells in HIV infection: functional and clinical correlations. J. Infect. Dis. 169, 730-738.
11. - T cells. AIDS 8, 431-441.
12. - cell population in the blood and lung of HIV-positive patients. J. Acquir. Immune Def. Syndr. 6, 1194-1204.
13. + lymphocyte homeostasis during the natural course of HIV-1 infection. J. Clin. Invest. 101, 137-144.
14. - T cell subsets in HIV type 1-infected patients. Eur. J. Immunol. 28, 1738-1742.
15. - T lymphocytes. Antigenic and functional properties. J. Immunol. 150, 1147-1159.
16. + cytotoxic T cells express CD38 and HLA-DR antigens. J. Immunol. 150, 3070-3079.
17. - lymphocytes in human immunodeficiency virus-specific cytotoxic activity. J. Virol. 70, 2022-2026.
18. - T lymphocytes by 4-1BB ligand. J. Immunol. 158, 551-559.
19. - T cells: B7-independent costimulation of CD1-restricted T cells. J. Exp. Med. 182, 2007-2018.
20. + lymphocyte subsets in acquired immunodeficiency syndrome (AIDS). J. Clin. Immunol. 8, 473-478.
21. Giorgi, J. V., Detels, R. (1989) T cell subsets alterations in HIV-infected homosexual men: NIAID multicenter AIDS cohort study. Clin. Immunol. Immunopathol. 52, 10-18.
22. Moretta, A., Pantaleo, G., Moretta, L., Cebottini, J. C., Mingari, M. C. (1983) Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolitic activity. J. Exp. Med. 157, 743-754.
23. Caruso, A., Licenziati, S., Canaris, A. D., Cantalamessa, A., Corulli, M., Benzoni. B., Peroni, L., Balsari, A., Turano, A. (1996) Characterization of T cell subsets involved in the production of IFN-γ asymptomatic HIV-infected patients. AIDS Res. Human Retroviruses 12, 135-141.
24. Graziosi, C., Pantaleo, G., Gantt, K. R., Fortin, J.-P., Demarest, J. F., Cohen, O. J., Sekaly, R. P., Fauci, A. S. (1994) Lack of evidence for the dichotomy of Th1 and Th2 predominance in HIV-infected individuals. Science 265, 248-252.
25. + T cell subset. Eur. J. Immunol. 28, 3630-3638.
26. Yamamura, R., Wang, X. H., Ohmen, J. D., Uyemura, K., Rea, T. H., Bloom, B. R., Modlin, R. L. (1992) Cytokine pattern of immunologically mediated tissue damage. J. Emmunol. 149, 1470-1475.
27. Lake, R. A., O'Hehir, R. E., Verhoef, A., Lamb, J. R. (1993) CD28 mRNA rapidly decays when activated T cells are functionally anergized with specific peptide. Int. Immunol. 5, 461-466.
28. Imberti, L., Sottini, A., Bettinardi, A., Puoti, M., Primi, D. (1991) Selective depletion in HIV infection of T cells that bear specific T cell receptor Vβ sequences. Science 254, 860-862.
29. Bettinardi, A., Imberti, L., Sottini, A., Primi, D. (1991) Analysis of amplified T cell receptor Vβ transcripts by a non isotypic immunoassay. J. Immunol. Meth. 146, 71-82.
30. Sottini, A., Quiròs-Roldan, E., Albertini, A., Primi, D., Imberti, L. (1996) Assessment of T cell receptor variable beta chains diversity by heteroduplex analysis. Hum. Immunol. 48, 12-22.
31. Villa, A., Santagata, S., Bozzi, F., Giliani, S., Frattini, A., Imberti, L., Benerini Gatta, L., Ochs, H. D., Schwarz, K., Notarangelo, L. D., Vezzoni P., Spanopoulou E. (1998) Partial V(D)J recombination activity leads to Omenn Syndrome. Cell 93, 885-896.
32. Mueller, D. L., Jenkins, M. K., Schwartz, R. H. (1989) An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness. J. Immunol. 142, 2617-2628.
33. + T cells. J. Immunol. 158, 1551-1558.
34. + T cell subsets isolated from chronic adult periodontitis tissue differ in surface phenotype and biological functions. Immunol. 87, 113-118.
35. Linsley, P. S., Bradshaw, J., Urnes, M., Grosmaire, L., Ledbetter, J. (1993) CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling. J. Immunol. 150, 3161-3169.
36. + T cells. Clin. Exp. Immunol. 100, 425-433.
37. + counterparts J. Immunol. 156, 3587-3590.
38. + cell counts: correlations with various parameters of disease progression. AIDS Res. Human Retroviruses 12, 497-506.