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Antisense and Nucleic Acid Drug Development

Volumn 10, Issue 6, 2000, Pages 435-441

Comparison of the pharmacokinetics of subcutaneous and intravenous administration of a phosphorothioate oligodeoxynucleotide in cynomolgus monkeys

(5) Leeds, J M a Henry, S P a Geary, R a Burckin, T a Levin, A A a

a ISIS PHARMACEUTICALS (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALICAFORSEN; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; MONKEY; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; MACACA FASCICULARIS;

EID: 0034530988 PISSN: 10872906 EISSN: None Source Type: Journal
DOI: 10.1089/oli.1.2000.10.435 Document Type: Article

Times cited : (22)

References (22)

1
- 0000397940
- Pharmacokinetics and bioavailability of antisense oligonucleotides following oral and colorectal administrations in experimental animals
- Antisense Research and Application. S. T. Crooke, ed. (Springer-Verlag, Berlin Heidelberg)
- (1998) , vol.131 , pp. 525-543
- Agrawal, S.¹ Zhang, R.²

2
- 12644302203
- Pharmacokinetic properties of several novel oligonucleotide analogs in mice
- (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 923-937
- Crooke, S.T.¹ Graham, M.J.² Zuckerman, J.E.³ Brooks, D.⁴ Conklin, B.S.⁵ Cummins, L.L.⁶ Greig, M.J.⁷ Guinosso, C.J.⁸ Kornburst, D.⁹ Manoharan, M.¹⁰ Sasmor, H.S.¹¹ Schleich, T.¹² Tivel, K.L.¹³ Griffey, R.H.¹⁴

3
- 0027527694
- Capillary gel electrophoresis and the analysis of DNA phosphorothioates
- (1993) J. Chromatogr. , vol.652 , pp. 101-108
- Dedionisio, L.¹

4
- 0000510535
- Antisense oligonucleotides to protein kinase C-α and C-raf kinase: Rationale and clinical experience in patients with solid tumors
- Antisense Research and Applications. S. T. Crooke, ed. (Springer-Verlag, Berlin Heidelberg)
- (1998) , vol.131 , pp. 461-476
- Dorr, F.A.¹ Kisner, D.L.²

5
- 0030667690
- Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-RAF-1 kinase expression
- (1997) Drug Metab. Dispos. , vol.25 , pp. 1272-1281
- Geary, R.S.¹ Leeds, J.M.² Fitchett, J.³ Burckin, T.⁴ Truong, L.⁵ Spainhour, C.⁶ Creek, M.⁷ Levin, A.A.⁸

6
- 0030797704
- Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides
- (1997) Anti-Cancer Drug Design , vol.12 , pp. 383-393
- Geary, R.S.¹ Leeds, J.M.² Henry, S.P.³ Monteith, D.K.⁴ Levin, A.A.⁵

7
- 0031936347
- Impact of 3′-exonuclease stereoselectivity on the kinetics of phosphorothioate oligonucleotide metabolism
- (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 35-42
- Gilar, M.¹ Belenky, A.² Budman, Y.³ Smisek, D.L.⁴ Cohen, A.S.⁵

8
- 0030987678
- Phase I safety and pharmacokinetic profile of an intercellular adhesion molecule-1 antisense oligodeoxynucleotide (ISIS 2302)
- (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1173-1180
- Glover, J.M.¹ Leeds, J.M.² Mant, T.G.K.³ Amin, D.⁴ Kisner, D.L.⁵ Zuckerman, J.E.⁶ Geary, R.S.⁷ Levin, A.A.⁸ Shanahan W.R., Jr.⁹

9
- 0030922755
- Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: Potential mechanism of action
- (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 810-816
- Henry, S.P.¹ Giclas, P.C.² Leeds, J.³ Pangburn, M.⁴ Auletta, C.⁵ Levin, A.A.⁶ Kornbrust, D.J.⁷

10
- 0030778162
- Effects of intravenous infusion of phosphorothioate oligonucleotides on coagulation, complement activation and hemodynamics
- (1997) Nucleosides Nucleotides , vol.16 , pp. 1673-1676
- Henry, S.P.¹ Monteith, D.² Kornbrust, D.J.³ Levin, A.A.⁴

11
- 0026048056
- Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection
- (1991) Nucleic Acids Res. , vol.19 , pp. 5743-5748
- Hoke, G.D.¹ Draper, K.² Freier, S.M.³ Gonzalez, C.⁴ Driver, V.B.⁵ Zounes, M.C.⁶ Ecker, D.J.⁷

12
- 0025250111
- 3H-1,2-Benzodithiole-3-one 1,1-dioxide as an improved sulfurizing reagent in the solid-phase synthesis of oligodeoxyribonucleoside phosphorothioates
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 1253-1254
- Iyer, R.P.¹ Egan, W.² Regan, J.B.³ Beaucage, S.L.⁴

13
- 9844240493
- Anti-BCL2 phosphorothioate G3139 clinical pharmacology: Plasma levels during continuous subcutaneous infusion by HPLC assay
- (1997) Nucleosides Nucleotides , vol.16 , pp. 1683-1687
- Lebedev, A.V.¹ Raynaud, F.² Dizik, M.³ Beck, T.⁴ Jaeger, J.A.⁵ Brown, B.D.⁶ Cunningham, D.⁷ Webb, A.⁸ McCampbell, E.⁹ Riley, T.¹⁰ Woodle, M.C.¹¹

14
- 0002574175
- Pharmacokinetic properties of phosphorothioate oligonucleotides in humans
- Antisense Research and Application. S.T. Crooke, ed. (Springer-Verlag, Berlin Heidelberg)
- (1998) , vol.131 , pp. 217-241
- Leeds, J.M.¹ Geary, R.S.²

15
- 0030781238
- Pharmacokinetic properties of phosphorothioate oligonucleotides
- (1997) Nucleosides Nucleotides , vol.16 , pp. 1689-1693
- Leeds, J.M.¹ Geary, R.S.² Henry, S.P.³ Glover, J.⁴ Shanahan, W.⁵ Flitchett, J.⁶ Burckin, T.⁷ Truong, L.⁸ Levin, A.A.⁹

16
- 0030065059
- Quantitation of phosphorothioate oligonucleotides in human plasma
- (1996) Anal. Biochem. , vol.235 , pp. 36-43
- Leeds, J.M.¹ Graham, M.J.² Truong, L.³ Cummins, L.L.⁴

17
- 0000172356
- Toxicity of oligodeoxynucleotide therapeutic agents
- Antisense Research and Application. S. T. Crooke, ed. (Springer-Verlag, Berlin Heidelberg)
- (1998) , vol.131 , pp. 167-215
- Levin, A.A.¹ Monteith, D.K.² Leeds, J.M.³ Nicklin, P.L.⁴ Geary, R.S.⁵ Butler, M.⁶ Templin, M.V.⁷ Henry, S.P.⁸

18
- 0031019342
- Binding affinity and specificity of Escherichia coli RNase H1: Impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids
- (1997) Biochemistry , vol.36 , pp. 390-398
- Lima, W.F.¹ Crooke, S.T.²

19
- 0030776403
- Pharmacokinetics, metabolism and elimination of a 20-mer phosphorothioate oligodeoxynucleotide (CGP 69846A) after intravenous and subcutaneous administration
- (1997) Biochem. Pharmacol. , vol.54 , pp. 657-668
- Phillips, J.A.¹ Craig, S.J.² Bayley, D.³ Christian, R.A.⁴ Geary, R.⁵ Nicklin, R.L.⁶

20
- 0031007491
- Pharmacokinetics of G3139, a phosphorothioate oligodeoxynucleotide antisense to bcl-2, after intravenous administration or continuous subcutaneous infusion to mice
- (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 420-427
- Raynaud, F.I.¹ Orr, R.M.² Goddard, P.M.³ Lacey, H.A.⁴ Lancashire, H.⁵ Judson, I.R.⁶ Beck, T.⁷ Bryan, B.⁸ Cotter, F.E.⁹

21
- 0030810546
- In vivo metabolic profile of a phosphorothioate oligodeoxyribonucleotide
- (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 159-165
- Temsamani, J.¹ Roskey, A.² Chaix, C.³ Agrawal, S.⁴

22
- 0029127845
- Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects
- (1995) Clin. Pharmacol. Ther. , vol.58 , pp. 44-53
- Zhang, R.¹ Yan, J.² Shahinian, H.³ Amin, G.⁴ Lu, Z.⁵ Liu, T.⁶ Saag, M.S.⁷ Jiang, Z.⁸ Temsamani, J.⁹ Martin, R.R.¹⁰ Schechter, P.J.¹¹ Agrawal, S.¹² Diasio, R.B.¹³

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