Characterization at the single-cell level of naive and primed CD8 T cell cytokine responses

Cellular Immunology

Volumn 206, Issue 1, 2000, Pages 16-25

  Walzer, Thierry ^a   Joubert, Greégoire ^a   Dubois, Patrice M ^b   Tomkowiak, Martine ^a   Arpin, Christophe ^a   Pihlgren, Maria ^c  

^a INSERM   (France)

^b GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Cellular activation; Cytokines; Memory; T lymphocytes

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; CYTOKINE PRODUCTION; IMMUNE RESPONSE; IMMUNE SYSTEM; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUPPRESSOR CELL; T LYMPHOCYTE;

EID: 0034495111     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1006/cimm.2000.1720     Document Type: Article

References (44)

1. Immunological memory and protective immunity: Understanding their relation
2. Antigen-specific development of primary and memory T cells in vivo
3. A kinetic basis for T cell receptor repertoire selection during an immune response
4. B cells turn off virgin but not memory T cells
5. On the cellular basis of immunological T cell memory
6. + T cells are hyperreactive to antigenic challenge in vitro
7. Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection
8. -) to TCR/CD8 signaling in response to antigen
9. Functional differences between memory and naive CD8 T cells
10. Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells
11. + memory T cells in virus-infected hosts
12. Kinetics of the response of naive and memory CD8 T cells to antigen: Similarities and differences
13. + T cells identified by expression of Pgp-1
14. In vivo persistence of CD8 polarized T cell subsets producing type I or type 2 cytokines
15. Memory CD44(int) CD8 T cells show increased proliferative responses and IFN-gamma production following antigenic challenge in vitro
16. + T cell function during in vivo memory or tolerance induction
17. - T cells
18. +) human T cells to multiple receptor-mediated stimuli but augmentation of responses by co-stimuli
19. Turnover of naive- and memory-phenotype T cells
20. On the role of antigen in maintaining cytotoxic T-cell memory
21. Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection
22. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
23. Differential requirements for survival and proliferation of CD8 naive or memory T cells
24. New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy
25. Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3: Simultaneous use of indo-1 and immunofluorescence with flow cytometry
26. CD8 expression allows T cell signaling by monomeric peptide-MHC complexes
27. Signal transduction through CD4 receptors: Stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD3/T cell receptor
28. Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivo
29. Helper T cell differentiation is controlled by the cell cycle
30. Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation
31. In vivo state of antiviral CTL precursors: Characterization of a cycling cell population containing CTL precursors in immune mice
32. Differential T cell receptor-mediated signaling in naive and memory CD4 T cells
33. + human T lymphocyte subsets
34. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
35. + T cells in primary and secondary influenza pneumonia
36. + memory T cells
37. Regulation of interferon-gamma gene expression
38. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
39. + T cells
40. Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene
41. 8 T lymphocytes
42. CD44: A multitude of isoforms with diverse functions
43. + T cells
44. Dealing from the evolutionary pawnshop: How lymphocytes make decisions