-
1
-
-
0032535760
-
The importance of local mucosal HIV-specific CD8(+) cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administration of IL-12
-
(1998)
J Clin Invest
, vol.102
, Issue.12
, pp. 2072-2081
-
-
Belyakov, I.M.1
Ahlers, J.D.2
Brandwein, B.Y.3
Earl, P.4
Kelsall, B.L.5
Moss, B.6
Strober, W.7
Berzofsky, J.A.8
-
2
-
-
0032932272
-
IL-12 is an effective adjuvant for induction of mucosal immunity
-
(1999)
J Immunol
, vol.162
, Issue.1
, pp. 122-128
-
-
Boyaka, P.N.1
Marinaro, M.2
Jackson, R.J.3
Menon, S.4
Kiyono, H.5
Jirillo, E.6
McGhee, J.R.7
-
4
-
-
0030798489
-
An adenovirus-simian immunodeficiency virus env vaccine elicits humoral, cellular, and mucosal immune responses in rhesus macaques and decreases viral burden following vaginal challenge
-
(1997)
J Virol
, vol.71
, Issue.11
, pp. 8531-8541
-
-
Buge, S.L.1
Richardson, E.2
Alipanah, S.3
Markham, P.4
Cheng, S.5
Kalyan, N.6
Miller, C.J.7
Lubeck, M.8
Udem, S.9
Eldridge, J.10
-
5
-
-
0026005836
-
Site-specific mutagenesis of the catalytic subunit of cholera toxin: Substituting lysine for arginine 7 causes loss of activity
-
(1991)
Infection and Immunity
, vol.59
, pp. 4266-4270
-
-
Burnette, W.N.1
Mar, V.L.2
Platler, B.W.3
Schlotterbeck, J.D.4
McGinley, M.D.5
Stoney, K.S.6
Rhode, M.F.7
Kaslow, H.R.8
-
6
-
-
0027378877
-
Development of mucosal protection against the heat-stable entero-toxin (ST) of Escherichia coli by oral immunization with a genetic fusion delivered by a bacterial vector
-
(1993)
Infect Immun
, vol.61
, Issue.11
, pp. 4629-4636
-
-
Cardenas, L.1
Clements, J.D.2
-
7
-
-
0344820782
-
Effectiveness of a vaccine composed of heat-killed Candida albicans and a novel mucosal adjuvant, LT(R192G), against systemic candidiasis
-
(1999)
Infect Immun
, vol.67
, Issue.2
, pp. 826-833
-
-
Cardenas-Freytag, L.1
Cheng, E.2
Mayeux, P.3
Domer, J.E.4
Clements, J.D.5
-
9
-
-
0032054708
-
LT(R192G), a non-toxic mutant of the heat-labile enterotoxin of Escherichia coli elicits enhanced humoral and cellular immune responses associated with protection against lethal oral challenge with Salmonella spp
-
(1998)
Vaccine
, vol.16
, Issue.7
, pp. 732-740
-
-
Chong, C.1
Frieberg, M.2
Clements, J.D.3
-
10
-
-
0023938398
-
Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens
-
(1988)
Vaccine
, vol.6
, pp. 269-277
-
-
Clements, J.D.1
Hartzog, N.M.2
Lyon, F.L.3
-
11
-
-
0031595032
-
Role of GM1 binding in the mucosal immunogenicity and adjuvant activity of the Escherichia coli heat-labile enterotoxin and its B subunit
-
(1998)
Immunology
, vol.94
, Issue.3
, pp. 424-430
-
-
De Haan, L.1
Verweij, W.R.2
Feil, I.K.3
Holtrop, M.4
Hol, W.G.5
Agsteribbe, E.6
Wilschut, J.7
-
12
-
-
0030066516
-
Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant
-
(1996)
Infect Immun
, vol.64
, Issue.3
, pp. 974-979
-
-
Di Tommaso, A.1
Saletti, G.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
Abrignani, S.6
Douce, G.7
De, M.T.8
-
15
-
-
0031911627
-
Delivery of antigen-encoding plasmid DNA into the cytosol of macrophages by attenuated suicide Listeria monocytogenes
-
(1998)
Nat Biotechnol
, vol.16
, Issue.2
, pp. 181-185
-
-
Dietrich, G.1
Bubert, A.2
Gentschev, I.3
Sokolovic, Z.4
Simm, A.5
Catic, A.6
Kaufmann, S.H.7
Hess, J.8
Szalay, A.A.9
Goebel, W.10
-
17
-
-
0002567252
-
Poly(lactide-co-glycolide) microencapsulation of vaccines for mucosal immunization
-
K. Hiroshi, P.L. Ogra, and J.R. McGhee, New York, Academic Press
-
(1996)
Mucosal vaccines
, pp. 159-173
-
-
Duncan, J.D.1
Gilley, R.M.2
Schafer, D.P.3
Moldoveanu, Z.4
Mestecky, J.F.5
-
19
-
-
0002061014
-
Regulation of small intestinal ion transport by cyclic nucleotides and calcium
-
M. Field, J.S. Fordtran, and S.G. Schultz. Baltimore, Md., Waverly Press
-
(1980)
Secretory diarrhea
, pp. 21-30
-
-
Field, M.1
-
21
-
-
0029031840
-
Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit
-
(1995)
Infection and Immunity
, vol.63
, pp. 2356-2360
-
-
Fontana, M.R.1
Manetti, R.2
Giannelli, V.3
Magagnoli, C.4
Marchini, A.5
Olivieri, R.6
Domenighini, M.7
Rappuoli, R.8
Pizza, M.9
-
24
-
-
0032489830
-
Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
-
(1998)
J Exp Med
, vol.187
, Issue.7
, pp. 1123-1132
-
-
Giuliani, M.M.1
Del Giudice, G.2
Giannelli, V.3
Dougan, G.4
Douce, G.5
Rappuoli, R.6
Pizza, M.7
-
27
-
-
0027930713
-
Construction and characterization of recombinant Vibrio_cholerae strains producing inactive cholera toxin analogs
-
(1994)
Infection and Immunity
, vol.62
, pp. 3051-3057
-
-
Häse, C.C.1
Thai, L.S.2
Boesman-Finkelstein, M.3
Mar, V.L.4
Burnette, W.N.5
Kaslow, H.R.6
Stevens, L.A.7
Moss, J.8
Finkelstein, R.A.9
-
28
-
-
0029959974
-
Antibody responses in volunteers induced by nasal influenza vaccine combined with Escherichia coli heat-labile enterotoxin B subunit containing a trace amount of the holotoxin
-
(1996)
Vaccine
, vol.14
, Issue.2
, pp. 113-119
-
-
Hashigucci, K.1
Ogawa, H.2
Ishidate, T.3
Yamashita, R.4
Kamiya, H.5
Watanabe, K.6
Hattori, N.7
Sato, T.8
Suzuki, Y.9
Nagamine, T.10
-
32
-
-
0031986227
-
Mutants of Escherichia coli heat-labile enterotoxin as an adjuvant for nasal influenza vaccine
-
(1998)
Vaccine
, vol.16
, Issue.2-3
, pp. 248-254
-
-
Komase, K.1
Tamura, S.-I.2
Matsuo, K.3
Watanabe, K.4
Hattori, N.5
Odaka, A.6
Suzuki, Y.7
Kurata, T.8
Aizawa, C.9
-
34
-
-
0029069313
-
Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis
-
(1995)
J Infect Dis
, vol.172
, Issue.1
, pp. 161-172
-
-
Lee, C.K.1
Weltzin, R.2
Thomas, W.D.3
Kleanthous, H.4
Ermak, T.H.5
Soman, G.6
Hill, J.E.7
Ackerman, S.K.8
Monath, T.P.9
-
39
-
-
10244230866
-
Immunogenicity and efficacy against lethal aerosol staphylococcal enterotoxin B challenge in monkeys by intramuscular and respiratory delivery of proteosome-toxoid vaccines
-
(1996)
Infect Immun
, vol.64
, Issue.11
, pp. 4686-4693
-
-
Lowell, G.H.1
Colleton, C.2
Frost, D.3
Kaminski, R.W.4
Hughes, M.5
Hatch, J.6
Hooper, C.7
Estep, J.8
Pitt, L.9
Topper, M.10
-
40
-
-
2642599064
-
Proteosomes, emulsomes, and cholera toxin B improve nasal immunogenicity of human immunodeficiency virus gpl60 in mice: Induction of serum intestinal, vaginal, and lung IgA and IgG
-
(1997)
J Infect Dis
, vol.175
, Issue.2
, pp. 292-301
-
-
Lowell, G.H.1
Kaminski, R.W.2
VanCott, T.C.3
Slike, B.4
Kersey, K.5
Zawoznik, E.6
Loomis-Price, L.7
Smith, G.8
Redfield, R.R.9
Amselem, S.10
-
44
-
-
0027056689
-
Liposomes and conjugate vaccines for antigen delivery and induction of mucosal immune responses
-
(1992)
Adv Exp Med Biol
, vol.327
, pp. 191-198
-
-
Michalek, S.M.1
Childers, N.K.2
Katz, J.3
Dertzbaugh, M.4
Zhang, S.5
Russell, M.W.6
Macrina, F.L.7
Jackson, S.8
Mestecky, J.9
-
50
-
-
0028853959
-
Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virus
-
(1995)
J Virol
, vol.69
, Issue.11
, pp. 6678-6686
-
-
Muster, T.1
Ferko, B.2
Klima, A.3
Purtscher, M.4
Trkola, A.5
Schulz, P.6
Grassauer, A.7
Engelhardt, O.G.8
Garcia-Sastre, A.9
Palese, P.10
-
52
-
-
0344073030
-
Safety and immunogenicity in volunteers of a new candidate mucosal adjuvant, LT(R192G)
-
Washington, D.C., American Society for Microbiology
-
(1997)
Program and abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Oplinger, M.L.1
Bakar, S.2
Trofa, A.F.3
Clements, J.D.4
Gibbs, P.5
Pazzaglia, G.6
Bourgeouis, A.L.7
Scott, D.A.8
-
53
-
-
0029905760
-
The adjuvant effect of a non-toxic mutant of heat-labile enterotoxin of Escherichia coli for the induction of measles virus-specific CTL responses after intranasal co-immunization with a synthetic peptide
-
(1996)
Immunology
, vol.89
, Issue.4
, pp. 483-487
-
-
Partidos, C.D.1
Pizza, M.2
Rappuoli, R.3
Steward, M.W.4
-
54
-
-
0027942083
-
Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis
-
(1994)
Molecular Microbiology
, vol.14
, pp. 51-60
-
-
Pizza, M.1
Domenighini, M.2
Hol, W.3
Giannelli, V.4
Fontana, M.R.5
Giuliani, M.M.6
Magagnoli, C.7
Peppoloni, S.8
Manetti, R.9
Rappuoli, R.10
-
55
-
-
0029008132
-
A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity. PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins
-
(1995)
Infect Immun
, vol.63
, Issue.6
, pp. 2100-2108
-
-
Roberts, M.1
Bacon, A.2
Rappuoli, R.3
Pizza, M.4
Cropley, I.5
Douce, G.6
Dougan, G.7
Marinaro, M.8
McGhee, J.9
Chatfield, S.10
-
58
-
-
0027174854
-
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin
-
(1993)
Journal of Molecular Biology
, vol.230
, pp. 890-918
-
-
Sixma, T.K.1
Kalk, K.H.2
Vanzanten, B.A.M.3
Dauter, Z.4
Kingma, J.5
Witholt, B.6
Hol, W.G.J.7
-
63
-
-
0005740809
-
Safety and enhanced immunogenicity in volunteers of an oral, inactivated, whole cell Campylobacter vaccine co-administered with a modified E. coli heat-labile enterotoxin adjuvant, LT (R192G)
-
Washington, D.C., American Society for Microbiology
-
(1997)
Program and abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Tribble, D.R.1
Bakar, S.2
Oplinger, M.L.3
Bourgeouis, A.L.4
Clements, J.D.5
Trofa, A.F.6
Pazzaglia, G.7
Pace, J.8
Walker, R.I.9
Gibbs, P.10
-
66
-
-
0030934988
-
Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae
-
(1997)
J Infect Dis
, vol.175
, Issue.4
, pp. 839-846
-
-
Wu, H.Y.1
Nahm, M.H.2
Guo, Y.3
Russell, M.W.4
Briles, D.E.5
-
68
-
-
0027183310
-
Helper T cell subsets for immunoglobulin A responses: Oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosal associated tissues
-
(1993)
Journal of Experimental Medicine
, vol.178
, pp. 1309-1320
-
-
Xu-Amano, J.1
Kiyono, H.2
Jackson, R.J.3
Staats, H.F.4
Fujihashi, K.5
Burrows, P.D.6
Elson, C.O.7
Pillai, S.8
McGhee, J.R.9
-
69
-
-
0029883627
-
The role of Th1 and Th2 cells for mucosal lgA responses
-
(1996)
Ann N Y Acad Sci
, vol.778
, pp. 64-71
-
-
Yamamoto, M.1
Vancott, J.L.2
Okahashi, N.3
Marinaro, M.4
Kiyono, H.5
Fujihashi, K.6
Jackson, R.J.7
Chatfield, S.N.8
Bluethmann, H.9
McGhee, J.R.10
-
70
-
-
0007205169
-
A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.10
, pp. 5267-5272
-
-
Yamamoto, S.1
Kiyono, H.2
Yamamoto, M.3
Imaoka, K.4
Fujihashi, K.5
Van, F.W.6
Noda, M.7
Takeda, Y.8
McGhee, J.R.9
-
71
-
-
0030902280
-
Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity
-
(1997)
Journal of Experimental Medicine
, vol.185
, pp. 1203-1210
-
-
Yamamoto, S.1
Takeda, Y.2
Yamamoto, M.3
Kurazono, H.4
Imaoka, K.5
Yamamoto, M.6
Fujihashi, K.7
Noda, M.8
Kiyono, H.9
McGhee, J.R.10
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