메뉴 건너뛰기




Volumn 76, Issue 3, 1998, Pages 263-269

Immune stimulating complexes as mucosal vaccines

Author keywords

Adjuvant; ISCOMs; Mucosa; Protein antigen; Saponin

Indexed keywords

ISCOM; OVALBUMIN; QUIL A; VACCINE;

EID: 0031817639     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.1998.00749.x     Document Type: Article
Times cited : (38)

References (63)
  • 1
    • 0027400165 scopus 로고
    • Novel vaccination strategies for the control of mucosal infection
    • Husband AJ. Novel vaccination strategies for the control of mucosal infection. Vaccine 1993; 11: 107-12.
    • (1993) Vaccine , vol.11 , pp. 107-112
    • Husband, A.J.1
  • 2
    • 0024856330 scopus 로고
    • Vaccines for the Third World
    • Bloom BR. Vaccines for the Third World. Nature 1989; 342: 115.
    • (1989) Nature , vol.342 , pp. 115
    • Bloom, B.R.1
  • 4
    • 0023146356 scopus 로고
    • The regulation of immune responses to dietary protein antigens
    • Mowat AMcI. The regulation of immune responses to dietary protein antigens. Immunol. Today 1987; 8: 93-5.
    • (1987) Immunol. Today , vol.8 , pp. 93-95
    • Mowat, A.McI.1
  • 5
    • 0028884598 scopus 로고
    • Adjuvants for human vaccines: Current status, problems and future prospects
    • Gupta RK, Siber GR. Adjuvants for human vaccines: Current status, problems and future prospects. Vaccine 1995; 13: 1263-76.
    • (1995) Vaccine , vol.13 , pp. 1263-1276
    • Gupta, R.K.1    Siber, G.R.2
  • 6
    • 0023882657 scopus 로고
    • The requirement of lipids for the formation of immune stimulating complexes (ISCOMs)
    • Lovegren K, Morein B. The requirement of lipids for the formation of immune stimulating complexes (ISCOMs). Biotechnol. Appl. Biochem. 1988; 10: 161-72.
    • (1988) Biotechnol. Appl. Biochem. , vol.10 , pp. 161-172
    • Lovegren, K.1    Morein, B.2
  • 7
    • 0024290352 scopus 로고
    • The ISCOMs antigen-presenting system
    • Morein B. The ISCOMs antigen-presenting system. Nature 1988; 332; 287-8.
    • (1988) Nature , vol.332 , pp. 287-288
    • Morein, B.1
  • 8
    • 0021255985 scopus 로고
    • Iscom, a novel structure for antigenic presentation of membrane proteins from enveloped viruses
    • Morein B, Sundquist B, Höglund S, Dalsgaard K, Osterhaus A. Iscom, a novel structure for antigenic presentation of membrane proteins from enveloped viruses. Nature 1984; 308: 457-60.
    • (1984) Nature , vol.308 , pp. 457-460
    • Morein, B.1    Sundquist, B.2    Höglund, S.3    Dalsgaard, K.4    Osterhaus, A.5
  • 9
    • 0023834354 scopus 로고
    • Influenza virus ISCOMs: Antibody response in animals
    • Sundquist B, Lövgren K, Morein B. Influenza virus ISCOMs: Antibody response in animals. Vaccine 1988; 6: 49-53.
    • (1988) Vaccine , vol.6 , pp. 49-53
    • Sundquist, B.1    Lövgren, K.2    Morein, B.3
  • 10
    • 0023472908 scopus 로고
    • Protection against lethal measles-virus infection in mice by immuno-stimulating complexes containing the haemagglutinin or fusion protein
    • Varsanyi TM, Morein B, Löve A, Norrby E. Protection against lethal measles-virus infection in mice by immuno-stimulating complexes containing the haemagglutinin or fusion protein. J. Virol. 1987; 61: 3896-901.
    • (1987) J. Virol. , vol.61 , pp. 3896-3901
    • Varsanyi, T.M.1    Morein, B.2    Löve, A.3    Norrby, E.4
  • 11
    • 0021867146 scopus 로고
    • Induction of protective immune response in cats by vaccination with feline leukaemia virus iscom
    • Osterhaus A, Weijer K, UytdeHaag F, Jarrett O, Sundquist B, Morein B. Induction of protective immune response in cats by vaccination with feline leukaemia virus iscom. J. Immunol. 1985; 135: 591-6.
    • (1985) J. Immunol. , vol.135 , pp. 591-596
    • Osterhaus, A.1    Weijer, K.2    Uytdehaag, F.3    Jarrett, O.4    Sundquist, B.5    Morein, B.6
  • 12
    • 0023840989 scopus 로고
    • Incorporation of the major outer membrane protein of Neisseria gonorrhoea in saponin-lipid complexes (ISCOMs): Chemical analysis, some structural features and comparison of their immunogenicity with three other antigen delivery systems
    • Kersten GFA, Teerlink T, Derks HJGK et al. Incorporation of the major outer membrane protein of Neisseria gonorrhoea in saponin-lipid complexes (ISCOMs): Chemical analysis, some structural features and comparison of their immunogenicity with three other antigen delivery systems. Infect. Immun. 1988; 56: 432-8.
    • (1988) Infect. Immun. , vol.56 , pp. 432-438
    • Kersten, G.F.A.1    Teerlink, T.2    Derks, H.J.G.K.3
  • 13
    • 0025373282 scopus 로고
    • Increased immunogenicity of a non-amphipathic protein (BSA) after inclusion into iscoms
    • Morein B, Ekstrom J, Lövgren K. Increased immunogenicity of a non-amphipathic protein (BSA) after inclusion into iscoms. J. Immunol. Methods 1990; 128: 177-81.
    • (1990) J. Immunol. Methods , vol.128 , pp. 177-181
    • Morein, B.1    Ekstrom, J.2    Lövgren, K.3
  • 14
    • 7144251270 scopus 로고
    • Preparation of immune stimulating complexes (ISCOMs) as adjuvants
    • Coligan JE, Kruisbeak M, Margulies DH, Shervach EM, Strober W (eds) Wiley Interscience
    • Mowat AMcI, Reid G. Preparation of immune stimulating complexes (ISCOMs) as adjuvants. In: Coligan JE, Kruisbeak M, Margulies DH, Shervach EM, Strober W (eds) Current Protocols in Immunology. 1992; 1: 2.11.1-2.11.12. Wiley Interscience.
    • (1992) Current Protocols in Immunology , vol.1 , pp. 2111-21112
    • Mowat, A.McI.1    Reid, G.2
  • 15
    • 0026697004 scopus 로고
    • Soluble-proteins incorporate into ISCOMs after covalent attachment of fatty acid
    • Reid G. Soluble-proteins incorporate into ISCOMs after covalent attachment of fatty acid. Vaccine 1992; 10: 597-602.
    • (1992) Vaccine , vol.10 , pp. 597-602
    • Reid, G.1
  • 16
    • 0026689113 scopus 로고
    • Incorporation of soluble antigens into ISCOMs: HIV gp120 ISCOMs induce virus neutralising antibodies
    • Browning M, Reid G, Osborne R, Jarrett O. Incorporation of soluble antigens into ISCOMs: HIV gp120 ISCOMs induce virus neutralising antibodies. Vaccine 1992; 10: 585-90.
    • (1992) Vaccine , vol.10 , pp. 585-590
    • Browning, M.1    Reid, G.2    Osborne, R.3    Jarrett, O.4
  • 17
    • 0029152948 scopus 로고
    • Induction of systemic and mucosal immune responses following immunisation with somatostatin-avidin complexes incorporated into ISCOMs
    • Estrada A, Laarveld B, Li B, Redmond MJ. Induction of systemic and mucosal immune responses following immunisation with somatostatin-avidin complexes incorporated into ISCOMs. Imm. Invest. 1995; 24: 819-28.
    • (1995) Imm. Invest. , vol.24 , pp. 819-828
    • Estrada, A.1    Laarveld, B.2    Li, B.3    Redmond, M.J.4
  • 18
    • 0024357678 scopus 로고
    • Antibody responses and protection in mice immunised with herpes simplex virus type I antigen immune-stimulating complex preparations
    • Ertürk M, Jennings R, Hockley D, Potter CW. Antibody responses and protection in mice immunised with herpes simplex virus type I antigen immune-stimulating complex preparations. J. Gen. Virol. 1989; 70: 2149-55.
    • (1989) J. Gen. Virol. , vol.70 , pp. 2149-2155
    • Ertürk, M.1    Jennings, R.2    Hockley, D.3    Potter, C.W.4
  • 19
    • 7144223510 scopus 로고
    • Influenza virus ISCOMs: Antibody response in animals
    • Lövgren K, Kaberg H, Morein B. Influenza virus ISCOMs: antibody response in animals. Vaccine 1988; 82: 435-9.
    • (1988) Vaccine , vol.82 , pp. 435-439
    • Lövgren, K.1    Kaberg, H.2    Morein, B.3
  • 20
    • 0023926388 scopus 로고
    • Immunogenicity of liposomes and ISCOMs containing the major outer membrane protein of Neisseria gonorrhoea: Influence of protein content and liposomal bilayer composition
    • Kersten GFA, van de Put A-M, Teerlink T, Beuvery EC, Crommelin DJA. Immunogenicity of liposomes and ISCOMs containing the major outer membrane protein of Neisseria gonorrhoea: Influence of protein content and liposomal bilayer composition. Infect. Immun. 1988; 56: 1661-4.
    • (1988) Infect. Immun. , vol.56 , pp. 1661-1664
    • Kersten, G.F.A.1    Van De Put, A.-M.2    Teerlink, T.3    Beuvery, E.C.4    Crommelin, D.J.A.5
  • 21
    • 0025686228 scopus 로고
    • ISCOMs (immunostimulating complex) vaccines containing mono-r polyvalent pili of enterotoxogenic E. coli; immune response of rabbit and swine
    • Nagy B, Hoglund S, Morein B. ISCOMs (immunostimulating complex) vaccines containing mono-r polyvalent pili of enterotoxogenic E. coli; immune response of rabbit and swine. J. Vet. Med. 1990; B37: 728-38.
    • (1990) J. Vet. Med. , vol.B37 , pp. 728-738
    • Nagy, B.1    Hoglund, S.2    Morein, B.3
  • 22
    • 0023766593 scopus 로고
    • The serum antibody response distributed in subclasses and isotypes after intranasal and subcutaneous immunisation with influenza virus immunostimulating complexes
    • Lövgren K. The serum antibody response distributed in subclasses and isotypes after intranasal and subcutaneous immunisation with influenza virus immunostimulating complexes. Scand. J. Immunol. 1988; 27: 241-5.
    • (1988) Scand. J. Immunol. , vol.27 , pp. 241-245
    • Lövgren, K.1
  • 23
    • 0025806703 scopus 로고
    • Immune stimulating complexes containing Quil A and protein antigen prime class 1 MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route
    • Mowat AMcI, Donachic AM, Reid G, Jarrett O. Immune stimulating complexes containing Quil A and protein antigen prime class 1 MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. Immunology 1991; 72: 317-22.
    • (1991) Immunology , vol.72 , pp. 317-322
    • Mowat, A.McI.1    Donachic, A.M.2    Reid, G.3    Jarrett, O.4
  • 24
    • 0025106451 scopus 로고
    • Effect of ISCOMs and their adjuvant moiety (Matrix) on the initial proliferation and IL-2 responses: Comparison of spleen cells from mice inoculated with ISCOMs and/or matrix
    • Fossum C, Bergstrom M, Lövgren K, Watson DL, Morein B. Effect of ISCOMs and their adjuvant moiety (Matrix) on the initial proliferation and IL-2 responses: Comparison of spleen cells from mice inoculated with ISCOMs and/or matrix. Cell. Immunol. 1990; 129: 414-25.
    • (1990) Cell. Immunol. , vol.129 , pp. 414-425
    • Fossum, C.1    Bergstrom, M.2    Lövgren, K.3    Watson, D.L.4    Morein, B.5
  • 25
    • 0026767896 scopus 로고
    • Involvement of interleukin-2 and interferon-gamma in the immune response induced by influenza virus ISCOMs
    • Villacrës-Eriksson M, Käberg H, Lövgren K, Morein B. Involvement of interleukin-2 and interferon-gamma in the immune response induced by influenza virus ISCOMs. Scand. J. Immunol. 1992; 36: 421-6.
    • (1992) Scand. J. Immunol. , vol.36 , pp. 421-426
    • Villacrës-Eriksson, M.1    Käberg, H.2    Lövgren, K.3    Morein, B.4
  • 27
    • 0028867560 scopus 로고
    • Antigen presentation by naive macrophages, dendritic cells and B cells to primed T lymphocytes and their cytokine production following exposure to immunostimulating complexes
    • Villacrës-Eriksson M. Antigen presentation by naive macrophages, dendritic cells and B cells to primed T lymphocytes and their cytokine production following exposure to immunostimulating complexes. Clin. Exp. Immunol. 1995; 102: 46-52.
    • (1995) Clin. Exp. Immunol. , vol.102 , pp. 46-52
    • Villacrës-Eriksson, M.1
  • 28
    • 0031562670 scopus 로고    scopus 로고
    • ISCOMs containing purified Quillaja saponins upregulate both Th1-like and Th2-like immune responses
    • Sjölander A, van't Land B, Lövgren-Bengtsson K. ISCOMs containing purified Quillaja saponins upregulate both Th1-like and Th2-like immune responses. Cell. Immunol. 1997; 177: 69-76.
    • (1997) Cell. Immunol. , vol.177 , pp. 69-76
    • Sjölander, A.1    Van't Land, B.2    Lövgren-Bengtsson, K.3
  • 32
    • 0025310910 scopus 로고
    • Induction of CD8+ cytotoxic T cells by immunisation with purified HIV-envelope proteins in iscoms
    • Takahashi H, Takeshita T, Morein B. Induction of CD8+ cytotoxic T cells by immunisation with purified HIV-envelope proteins in iscoms. Nature 1990; 344: 873-5.
    • (1990) Nature , vol.344 , pp. 873-875
    • Takahashi, H.1    Takeshita, T.2    Morein, B.3
  • 33
    • 0025762026 scopus 로고
    • + cytotoxic T lymphocytes towards soluble antigens: Immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitisation against the immunodominant peptide
    • + cytotoxic T lymphocytes towards soluble antigens: Immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitisation against the immunodominant peptide. J. Immunol. 1991; 21: 1523-7.
    • (1991) J. Immunol. , vol.21 , pp. 1523-1527
    • Heeg, K.1    Kuon, W.2    Wagner, H.3
  • 34
    • 0023677230 scopus 로고
    • Cellular immune responses in the murine lung to local immunisation with influenza a virus glycoproteins in micelles and immunostimulatory complexes (ISCOMs)
    • Jones PD, Tha Hla R, Morein B, Lövgren K, Ada GL. Cellular immune responses in the murine lung to local immunisation with influenza A virus glycoproteins in micelles and immunostimulatory complexes (ISCOMs). Scand. J. Immunol. 1988; 27: 645-52.
    • (1988) Scand. J. Immunol. , vol.27 , pp. 645-652
    • Jones, P.D.1    Tha Hla, R.2    Morein, B.3    Lövgren, K.4    Ada, G.L.5
  • 35
    • 0026530511 scopus 로고
    • Initiation of cytotoxic T-cell response and protection of Balb/c mice by vaccination with an experimental ISCOMs respiratory syncytial virus subunit vaccine
    • Trudel M, Nadon F, Sëguin C, Brault S, Lusignan Y. Initiation of cytotoxic T-cell response and protection of Balb/c mice by vaccination with an experimental ISCOMs respiratory syncytial virus subunit vaccine. Vaccine 1992; 10: 107-12.
    • (1992) Vaccine , vol.10 , pp. 107-112
    • Trudel, M.1    Nadon, F.2    Sëguin, C.3    Brault, S.4    Lusignan, Y.5
  • 36
    • 0027137598 scopus 로고
    • Immune stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunisation with protein antigens
    • Mowat AMcI, Maloy KJ, Donachie AM. Immune stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunisation with protein antigens. Immunology 1993; 80: 527-34.
    • (1993) Immunology , vol.80 , pp. 527-534
    • Mowat, A.McI.1    Maloy, K.J.2    Donachie, A.M.3
  • 39
    • 0025991258 scopus 로고
    • Macrophages as accessory for class I MHC-restricted immune responses
    • Debrick JE, Campbell PA, Staerz UD. Macrophages as accessory for class I MHC-restricted immune responses. J. Immunol. 1991; 147: 2846-51.
    • (1991) J. Immunol. , vol.147 , pp. 2846-2851
    • Debrick, J.E.1    Campbell, P.A.2    Staerz, U.D.3
  • 40
    • 0027292868 scopus 로고
    • Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages
    • Kovacsovics-Bankowski M, Clark K, Benacerraf B, Rock KL. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc. Natl Acad. Sci. USA 1993; 90: 4942-6.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 4942-4946
    • Kovacsovics-Bankowski, M.1    Clark, K.2    Benacerraf, B.3    Rock, K.L.4
  • 41
    • 0028052101 scopus 로고
    • Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules
    • Harding CV, Song R. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. J. Immunol. 1994; 153: 4925-33.
    • (1994) J. Immunol. , vol.153 , pp. 4925-4933
    • Harding, C.V.1    Song, R.2
  • 42
    • 0025201211 scopus 로고
    • An experimental influenza subunit vaccine (iscom): Induction of protective immunity to challenge infection in mice after intranasal or subcutaneous administration
    • Lövgren K, Kaberg H, Morein B. An experimental influenza subunit vaccine (iscom): induction of protective immunity to challenge infection in mice after intranasal or subcutaneous administration. J. Exp. Immunol. 1990; 82: 435-9.
    • (1990) J. Exp. Immunol. , vol.82 , pp. 435-439
    • Lövgren, K.1    Kaberg, H.2    Morein, B.3
  • 43
    • 0028337348 scopus 로고
    • Adjuvented subunit vaccines for the control of Salmonella enteritidis infection in turkeys
    • Charles SD, Hussain I, Choi CU, Nagaraja KV, Sivanandan V. Adjuvented subunit vaccines for the control of Salmonella enteritidis infection in turkeys. Am. J. Vet. Res. 1994; 55: 636-42.
    • (1994) Am. J. Vet. Res. , vol.55 , pp. 636-642
    • Charles, S.D.1    Hussain, I.2    Choi, C.U.3    Nagaraja, K.V.4    Sivanandan, V.5
  • 44
    • 0025776527 scopus 로고
    • Immunisation with Trypanosoma cruzi epimastigote antigens incorporated into ISCOMs protects against lethal challenge in mice
    • Araujo FG, Morein B. Immunisation with Trypanosoma cruzi epimastigote antigens incorporated into ISCOMs protects against lethal challenge in mice. Infect. Immun. 1991; 59: 2909-14.
    • (1991) Infect. Immun. , vol.59 , pp. 2909-2914
    • Araujo, F.G.1    Morein, B.2
  • 45
    • 0026080815 scopus 로고
    • Immune response after immunisation with an experimental Toxoplasma gondii ISCOMs
    • Overness G, Nesse NN, Waldeland N, Lövgren K, Gudding R. Immune response after immunisation with an experimental Toxoplasma gondii ISCOMs. Vaccine 1991; 9: 25-8.
    • (1991) Vaccine , vol.9 , pp. 25-28
    • Overness, G.1    Nesse, N.N.2    Waldeland, N.3    Lövgren, K.4    Gudding, R.5
  • 46
    • 0030581353 scopus 로고    scopus 로고
    • Linkage of a fusion peptide to a CTL epitope from the nucleoprotein of measles virus enables incorporation into ISCOMs and the induction of CTL responses following intranasal immunisation
    • Hsu S-C, Schadeck EB, Delmas A, Shaw M, Steward MW. Linkage of a fusion peptide to a CTL epitope from the nucleoprotein of measles virus enables incorporation into ISCOMs and the induction of CTL responses following intranasal immunisation. Vaccine 1996; 14: 1159-66.
    • (1996) Vaccine , vol.14 , pp. 1159-1166
    • Hsu, S.-C.1    Schadeck, E.B.2    Delmas, A.3    Shaw, M.4    Steward, M.W.5
  • 48
    • 0023194411 scopus 로고
    • Immunomodulatory effects of orally-administered saponins and non-specific resistance against rabies infection
    • Chavali SR, Campbell J. Immunomodulatory effects of orally-administered saponins and non-specific resistance against rabies infection. Int. Arch. Allergy Appl. Immun. 1987; 84: 129-34.
    • (1987) Int. Arch. Allergy Appl. Immun. , vol.84 , pp. 129-134
    • Chavali, S.R.1    Campbell, J.2
  • 49
    • 0023223117 scopus 로고
    • Adjuvant effects of orally administered saponins on humoral and cell-mediated immune responses in mice
    • Chavali SR, Campbell J. Adjuvant effects of orally administered saponins on humoral and cell-mediated immune responses in mice. Immunobiology 1987; 174: 347-59.
    • (1987) Immunobiology , vol.174 , pp. 347-359
    • Chavali, S.R.1    Campbell, J.2
  • 50
    • 0028836530 scopus 로고
    • Comparative antibody responses and protection in mice immunised by oral or parenteral routes with influenza virus subunit antigens in aqueous form or incorporated into ISCOMs
    • Ghazi HO, Potter CW, Smith TL, Jennings R. Comparative antibody responses and protection in mice immunised by oral or parenteral routes with influenza virus subunit antigens in aqueous form or incorporated into ISCOMs. Viral Vaccines 1995; 42: 53-61.
    • (1995) Viral Vaccines , vol.42 , pp. 53-61
    • Ghazi, H.O.1    Potter, C.W.2    Smith, T.L.3    Jennings, R.4
  • 51
    • 0028566804 scopus 로고
    • Protection of mice against an influenza-virus infection by oral vaccination with viral nucleoprotein incorporated into immunostimulating complexes
    • Scheepers K, Becht H. Protection of mice against an influenza-virus infection by oral vaccination with viral nucleoprotein incorporated into immunostimulating complexes. Med. Microbiol. Immunol. 1994; 183: 265-78.
    • (1994) Med. Microbiol. Immunol. , vol.183 , pp. 265-278
    • Scheepers, K.1    Becht, H.2
  • 52
    • 0028243439 scopus 로고
    • Immune responses and protective effect in mice vaccinated orally with surface sporozoite protein of Eimeria falciformis in ISCOMs
    • Kazanji M, Laurent F, Perry P. Immune responses and protective effect in mice vaccinated orally with surface sporozoite protein of Eimeria falciformis in ISCOMs. Vaccine 1994; 12: 798-804.
    • (1994) Vaccine , vol.12 , pp. 798-804
    • Kazanji, M.1    Laurent, F.2    Perry, P.3
  • 54
    • 0026027127 scopus 로고
    • Secretory immune responses in the mouse vagina after parenteral or intravaginal immunisation with an immunostimulating complex (ISCOMs)
    • Thapar MA, Parr EJ, Bozzola JJ, Parr MB. Secretory immune responses in the mouse vagina after parenteral or intravaginal immunisation with an immunostimulating complex (ISCOMs). Vaccine 1991; 9: 129-33.
    • (1991) Vaccine , vol.9 , pp. 129-133
    • Thapar, M.A.1    Parr, E.J.2    Bozzola, J.J.3    Parr, M.B.4
  • 55
    • 0028049676 scopus 로고
    • Induction of mucosal and systemic immune responses by immunisation with ovalbumin entrapped in poly (lactide-coglycolide) microparticles
    • Maloy KJ, Donachie AM, O'Hagan DT, Mowat AMcI. Induction of mucosal and systemic immune responses by immunisation with ovalbumin entrapped in poly (lactide-coglycolide) microparticles. Immunology 1994; 81: 661-7.
    • (1994) Immunology , vol.81 , pp. 661-667
    • Maloy, K.J.1    Donachie, A.M.2    O'Hagan, D.T.3    Mowat, A.McI.4
  • 56
    • 7144227360 scopus 로고
    • Fluorescent labelling of virus, bacteria and ISCOMs: In vivo systemic and mucosal localisation patterns
    • Brandtzaeg P, McGhee JR, Mestecky J, Sterzl G, Tlaskalova H (eds) New York: Plenum Press
    • Claassen I, Osterhaus A, Boersma WJA, Chellekens MM, Claassen E. Fluorescent labelling of virus, bacteria and ISCOMs: In vivo systemic and mucosal localisation patterns. In: Brandtzaeg P, McGhee JR, Mestecky J, Sterzl G, Tlaskalova H (eds) Advances in Mucosal Immunology. New York: Plenum Press, 1992.
    • (1992) Advances in Mucosal Immunology
    • Claassen, I.1    Osterhaus, A.2    Boersma, W.J.A.3    Chellekens, M.M.4    Claassen, E.5
  • 57
    • 0028867560 scopus 로고
    • Antigen presentation by naive macrophages, dendritic cells and B cells to primed T lymphocytes and their cytokine production following exposure to immunostimulating complexes
    • Villacres-Eriksson M. Antigen presentation by naive macrophages, dendritic cells and B cells to primed T lymphocytes and their cytokine production following exposure to immunostimulating complexes. Clin. Exp. Immunol. 1995; 102: 46-52.
    • (1995) Clin. Exp. Immunol. , vol.102 , pp. 46-52
    • Villacres-Eriksson, M.1
  • 58
    • 0031239111 scopus 로고    scopus 로고
    • In vivo and in vitro induction of IL-6 by Quillaja saponaria Molina triterpenoid formulations
    • Behboudi S, Morein B, Villacres-Eriksson M. In vivo and in vitro induction of IL-6 by Quillaja saponaria Molina triterpenoid formulations. Cytokine 1997; 9: 682-7.
    • (1997) Cytokine , vol.9 , pp. 682-687
    • Behboudi, S.1    Morein, B.2    Villacres-Eriksson, M.3
  • 59
    • 0031081461 scopus 로고    scopus 로고
    • Immunomodulation by Quillaja saponaria adjuvant formulations: In vivo stimulation of interleukin 12 and its effects on the antibody response
    • Villacres-Eriksson M, Behboudi S, Morgan AJ, Trinchieri G, Morein B. Immunomodulation by Quillaja saponaria adjuvant formulations: In vivo stimulation of interleukin 12 and its effects on the antibody response. Cytokine 1997; 9: 73.
    • (1997) Cytokine , vol.9 , pp. 73
    • Villacres-Eriksson, M.1    Behboudi, S.2    Morgan, A.J.3    Trinchieri, G.4    Morein, B.5
  • 60
    • 0031946347 scopus 로고    scopus 로고
    • Preservation of systemic and mucosal immune responses to immune stimulating complexes in the absence of functional interleukin 4 or γ interferon
    • Smith RE, Donachie AM, McLaren FH, Mowat AMcI. Preservation of systemic and mucosal immune responses to immune stimulating complexes in the absence of functional interleukin 4 or γ interferon. Immunology 1998; 93: 556-62.
    • (1998) Immunology , vol.93 , pp. 556-562
    • Smith, R.E.1    Donachie, A.M.2    McLaren, F.H.3    Mowat, A.McI.4
  • 61
    • 0031563755 scopus 로고    scopus 로고
    • Differential effects of LPS and CD40 ligand stimulations on the induction of IL-12 production by dendritic cells and macrophages
    • Kato T, Yamane H, Nariuchi H. Differential effects of LPS and CD40 ligand stimulations on the induction of IL-12 production by dendritic cells and macrophages. Cell. Immunol. 1997; 181: 59-67.
    • (1997) Cell. Immunol. , vol.181 , pp. 59-67
    • Kato, T.1    Yamane, H.2    Nariuchi, H.3
  • 62
    • 0028906467 scopus 로고
    • Impaired mucosal immune responses in interleukin 4-targeted mice
    • Vajdy M, Kosco-Vilbois, Kopf M, Köhler G, Lycke N. Impaired mucosal immune responses in interleukin 4-targeted mice. J. Exp. Med. 1995; 181: 41-53.
    • (1995) J. Exp. Med. , vol.181 , pp. 41-53
    • Vajdy, M.1    Kosco-Vilbois2    Kopf, M.3    Köhler, G.4    Lycke, N.5
  • 63
    • 0028856624 scopus 로고
    • Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOMs matrix
    • Rönnberg B, Makonnen F, Morein B. Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOMs matrix. Vaccine 1995; 13: 1375-82.
    • (1995) Vaccine , vol.13 , pp. 1375-1382
    • Rönnberg, B.1    Makonnen, F.2    Morein, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.