TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture

Molecular and Cellular Biology

Volumn 20, Issue 23, 2000, Pages 8996-9008

  Herold, A ^a   Suyama, M ^a   Rodrigues, J P ^a   Braun, I C ^a   Kutay, U ^a   Carmo Fonseca, M ^a   Bork, P ^a   Izaurralde, E ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MESSENGER RNA; NUCLEOPROTEIN; RNA;

ARTICLE; CELL NUCLEUS MEMBRANE; GENE STRUCTURE; GENETIC CONSERVATION; HUMAN; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; RNA TRANSPORT;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; CONSERVED SEQUENCE; DIMERIZATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; GENE DUPLICATION; HUMANS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NUCLEAR PORE; NUCLEAR PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; EUKARYOTA; MELANOGASTER; VERTEBRATA;

EID: 0034460814     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.23.8996-9008.2000     Document Type: Article

References (43)

1. The genome sequence of Drosophila melanogaster
2. Microinjection of anti-coilin antibodies affects the structure of coiled bodies
3. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
4. The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
5. Identification of novel import and export signals of human TAP, the protein that binds to the CTE element of the type D retrovirus mRNAs
6. The human RAE1 gene is a functional homologue of Schizosaccharomyces pombe rae1 gene involved in nuclear export of Poly(A)+ RNA
7. Identification of an NTF2-related factor that binds RanGTP and regulates nuclear protein export
8. TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus
9. A mutation in the Schizosaccharomyces pombe rae1 gene causes defects in poly(A)+ RNA export and in the cytoskeleton
10. Genome sequence of the nematode C. elegans: A platform for investigating biology
11. SEAVIEW and PHYLO_WIN: Two graphic tools for sequence alignment and molecular phylogeny
12. TAP, the human homologue of Mex67p, mediates CTE-dependent RNA export from the nucleus
13. Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: Mapping cryptic functions of the arginine-rich motif
14. Minimal Rev-response element for type 1 human immunodeficiency virus
15. The human TAP protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences
16. Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element
17. The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human
18. Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm
19. Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1
20. mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm
21. Dominant-negative mutants of importin-β block multiple pathways of import and export through the nuclear pore complex
22. Nucleocytoplasmic transport: The soluble phase
23. Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions
24. The structure of the mRNA nuclear export factor TAP reveals a cis arrangement of a non-canonical RNP domain and a leucine-rich-repeat domain
25. The acute myeloid leukemia-associated protein DEK forms a splicing-dependent interaction with exon-product complexes
26. A novel rapid assay for Chloramphenicol-acetyl transferase gene expression
27. GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function
28. Transport of proteins and RNAs in and out of the nucleus
29. Release of proteins and peptides from fusion proteins with a recombinant plant virus proteinase
30. The constitutive transport element (CTE) of Mason-Pfizer Monkey Virus (MPMV) accesses an RNA export pathway utilized by cellular messenger RNAs
31. RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains
32. The nuclear pore complex: A protein machine bridging the nucleus and cytoplasm
33. The simian retrovirus-1 constitutive transport element CTE, unlike HIV-1 RRE, utilises factors required for cellular RNA export
34. The neighbor-joining method: A new method for reconstructing phylogenetic trees
35. Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores
36. Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores
37. Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export
38. Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export
39. REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export
40. Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins
41. The mRNA export in C. elegans is mediated by Ce-TAP1, an orthologue of human TAP and S. cerevisiae Mex67p
42. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
43. NUP98 is required for gastrulation, proper nuclear pore complex assembly and efficient protein import