Plants as 'chemical factories' for the production of polyunsaturated fatty acids

Biotechnology Advances

Volumn 18, Issue 6, 2000, Pages 481-497

  Alonso, D López ^a   Maroto, F García ^a  

^a UNIVERSITY OF ALMERÍA   (Spain)

Author keywords

Desaturases; Genetic engineering; Oilseed plants; Polyunsaturated fatty acids

Indexed keywords

GENETIC ENGINEERING; GENETIC TRANSFORMATION; OILSEED; POLYUNSATURATED FATTY ACID;

GENETIC ENGINEERING; HEALTH CARE; PLANTS (BOTANY); UNSATURATED COMPOUNDS;

POLYUNSATURATED FATTY ACIDS (PUFA);

FATTY ACIDS;

EID: 0034305209     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0734-9750(00)00048-3     Document Type: Article

References (94)

1. Biosynthesis of polyunsaturated lipids in the diatom, Phaeodactylum tricornutum
2. Biosynthesis of polyunsaturated fatty acids in the marine diatom, Phaeodactylum tricornutum
3. Eicosapentaenoic acid (EPA) production from microorganisms: A review
4. Heterotrophic production of long chain omega-3 fatty acids utilizing algae and algae-like microorganisms
5. A process for high yield and scaleable recovery of high purity eicosapentaenoic acid esters from microalgae and fish oil
6. Nucleotide sequence of a cDNA from Limnanthes douglasii L. encoding a delta-15 linoleic acid desaturase
7. Baby formula needs essential extras
8. Glycerolipid synthesis: Biochemistry and regulation
9. Uses of biotechnology in modifying plant lipids
10. Cloning and characterization of a seed-specific 8.0 ω-3 fatty acid desaturase cDNA from Perilla frutescens
11. New sources of stearidonic acid and the moderation of inflammation by plant oils containing stearidonate
12. Linolenate-derived polyunsaturated fatty acids and prevention of atherosclerosis
13. Improved stearate phenotype in transgenic canola expressing a modified acyl-acyl carrier protein thioesterase
14. Transgenic canola and soybean seeds with increased lysine
15. Identification of a gene that complements an Arabidopsis mutant deficient in chloroplast ω-6 desaturase activity
16. Recent developments and perspectives of industrial rapeseed breeding
17. 9-desaturase in rose petals
18. Cloning of a temperature-regulated gene encoding a chloroplast ω-3 desaturase from Arabidopsis thaliana
19. Polyunsaturated fatty acids, part 1: Occurrence, biological activities and applications
20. Identification of a novel delta6-acyl-group desaturase by targeted gene disruption in Physcomitrella patens
21. Gamma linolenic acid-occurrence and physical and chemical properties
22. Movements towards tailor-made fats
23. A silence that speaks volumes
24. Cloning of a cDNA encoding tobacco omega-3 fatty acid desaturase
25. Fatty acid metabolism
26. Recent advances in the biosynthesis of plant fatty acids
27. Developmental and growth temperature regulation of two different microsomal omega-6 desaturase genes in soybeans
28. Cloning of a higher-plant plastid ω-6 fatty acid desaturase cDNA and its expression in a cyanobacterium
29. Reducing polyunsaturation in oils of transgenic canola and soybean
30. Developmental regulation of genes from microsome and plastid omega-3 fatty acid desaturases in wheat (Triticum aestivum L.)
31. Nutritional and medical importance of gamma-linolenic acid
32. Cloning of Δ12- and Δ6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae
33. Effects of polyunsaturated fats on blood pressure
34. Essential fatty acids in growth and development
35. High efficiency transformation of maize (Zea mays L.) mediated by Agrobacterium tumefaciens
36. Direct tagging of the Arabidopsis fatty acid elongation 1 (FAE 1) gene with the maize transposon activator
37. A novel Δ5-desaturase-defective mutant of Mortierella alpina 1S-4 and its dihomo-γ-linolenic acid productivity
38. Genetic modification of the storage lipids of plants
39. Plants as industrial chemical factories - New oils from genetically engineered soybeans
40. Modification of Brassica seed oil by antisense expression of a stearoyl-acyl carrier protein desaturase gene
41. Identification of Δ5-desaturase from Mortierella alpina by heterologous expression in bakers' yeast and canola
42. Listening to the silent genes: Transgene silencing, gene regulation and pathogen control
43. Transgenic oilseed crops: A transition from basic research to product development
44. Fatty acid variation among different isolates of a single strain of Isochrysis galbana
45. First insights into improvement of eicosapentaenoic acid content in Phaeodactylum tricornutum (Bacillariophyceae) by induced mutagenesis
46. Genetic improvement of EPA content in microalgae
47. 5-fatty acid desaturase gene from Mortierella alpina
48. Accumulation of very-long-chain fatty acids in membrane glycerolipids is associated with dramatic alterations in plant morphology
49. High-oleate oilseeds fail to develop at low temperature
50. Structure, function and biogenesis of storage lipids bodies and oleosins in plants
51. The use of conventional and molecular genetics to produce new diversity in seed oil composition for the use of plant breeders-progress, problems and future prospects
52. Engineering oil production in rapeseed and other oil crops
53. Plant desaturases: Harvesting the fat of the land
54. Diet therapy in coronary disease
55. Are n-3 fatty acids essential nutrients for fetal and infant development?
56. Chilling sensitivity in plants and cyanobacteria: The crucial contribution of membrane lipids
57. Developmental and hormonal regulation of sunflower helianthinin genes: Proximal promoter sequences confer regionalized seed expression
58. Regulation of fatty acid biosynthesis
59. Design of new plant products: Engineering of fatty acid metabolism
60. Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis
61. Selective modulation of the human platelet thromboxane A2/prostaglandine H2 receptor by eicosapentaenoic and docosahexaenoic acids in intact platelets and solubilized platelet membranes
62. Interactions of lipids with immune function II - Experimental and clinical studies of lipids and immunity
63. High-frequency linkage of co-expressing T-DNA in transgenic Arabidopsis thaliana transformed by vacuum-infiltration of Agrobacterium tumefaciens
64. Microbial routes to lipids
65. Single cell oils - Have they a biotechnological future?
66. 6-desaturase gene from the cyanobacterium Synechocystis sp. strain PCC 6803 by gain-of-function expression in Anabaena sp. strain PCC 7120
67. 6-desaturase gene results in γ-linolenic acid production in transgenic plants
68. Delta-9 acyl-lipid desaturases of cyanobacteria
69. Expression and subcellular targeting of a soybean oleosin in transgenic rapeseed. Implications for the mechanism of oil-body formation in seeds
70. 6-desaturase from Borago officinalis
71. 6-desaturated fatty acids in transgenic tobacco
72. Purification and PCR-based cDNA cloning of a plastidial n-6 desaturase
73. Production of eicosapentaenoic acid by Mortierella fungi
74. Omega-3 fatty acids in health and disease and in growth and development
75. Adipose tissue omega-3 and omega-6 fatty acid content and breast cancer in the EURAMIC study
76. Biochemical and cellular effects of fish and fish oils
77. The biochemistry and molecular biology of plant lipid biosynthesis
78. Plant lipids: Metabolism, mutants, and membranes
79. A cytochrome-b5-containing fusion protein similar to plant acyl lipid desaturases
80. Identification of an animal ω-3 fatty acid desaturase by heterologous expression in Arabidopsis
81. Distinct features of post-transcriptional gene silencing by antisense transgenes in single copy and inverted T-DNA repeat loci
82. Genetic transformation, recovery, and characterization of fertile soybean transgenic for a synthetic Bacillus thuringiensis cryIAc gene
83. Analysis of the 5' flanking region responsible for the endosperm-specific expression of a rice glutelin chimeric gene in transgenic tobacco
84. Modification of plant lipid synthesis
85. Fatty acid biosynthesis redirected to medium chains in transgenic oilseed plants
86. Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation
87. Dietary fats and oils in human nutrition
88. Phase II trials of high purity eicosapentaenoic acid (EPA) in patient with pancreatic cancer cachexia
89. The effect of PUFA on the progress of cachexia in patients with pancreatic cancer
90. Cloning of higher plant omega-3 fatty acid desaturases
91. Production of eicosapentaenoic acid by marine bacteria
92. Omega-3 fatty acids: Alternative sources of production
93. Screening of algae for potential alternative sources of eicosapentaenoic acid