Growth factor receptor signalling: Location, location, location

Trends in Cell Biology

Volumn 10, Issue 8, 2000, Pages 343-348

  Leof, Edward B ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; MEMBRANE RECEPTOR; PROTEIN SERINE THREONINE KINASE;

CELL MEMBRANE; CELL TYPE; CELLULAR DISTRIBUTION; ENDOSOME; HUMAN; LIGAND BINDING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; GROWTH SUBSTANCES; HUMANS; RECEPTORS, GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 0034255905     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0962-8924(00)01795-5     Document Type: Review

References (68)

1. Heldin C.H.et al. Signal transduction via platelet-derived growth factor receptors. Biochem. Biophys. Acta. 1378:1998;F79-F113.
2. Hackel P.O.et al. Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr. Opin. Cell Biol. 11:1999;184-189.
3. Bevan A.P.et al. Intracellular signal transduction: the role of endosomes. Trends Endocrinol. Metab. 7:1996;13-21.
4. Kirchhausen T.et al. Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr. Opin. Cell Biol. 9:1997;488-495.
5. Kurzchalia T.V., Parton R.G. Membrane microdomains and caveolae. Curr. Opin. Cell Biol. 11:1999;424-431.
6. Schmid S.L. Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu. Rev. Biochem. 66:1997;511-548.
7. Schmid S.L.et al. Dynamin and its partners: a progress report. Curr. Opin. Cell Biol. 10:1998;504-512.
8. Sweitzer S.M., Hinshaw J.E. Dynamin undergoes a GTP-dependent conformational change causing vesiculation. Cell. 5:1998;1021-1029.
9. Sever S.et al. Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis. Nature. 398:1999;481-486.
10. Hicke L. Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels. Trends Cell Biol. 9:1999;107-112.
11. Ceresa B.P., Schmid S.L. Regulation of signal transduction by endocytosis. Curr. Opin. Cell Biol. 12:2000;202-210.
12. DiFiore P.P., Gill G.N. Endocytosis and mitogenic signaling. Curr. Opin. Cell Biol. 11:1999;483-488.
13. Wells A. EGF receptor. Int. J. Biochem. Cell Biol. 31:1999;637-643.
14. Gullick W.J., Srinivasan R. The type 1 growth factor receptor family: new ligands and receptors and their role in breast cancer. Br. Cancer Res. Treat. 52:1998;43-53.
15. Baulida J.et al. All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem. 271:1996;5251-5257.
16. Sorkin A., Water C.M. Endocytosis of growth factor receptors. BioEssays. 15:1993;375-382.
17. Chen W.S.et al. Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell. 59:1989;33-43.
18. Glenney J.et al. Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of antiphosphotyrosine antibodies. Cell. 52:1988;675-684.
19. Felder S.et al. Kinetics of binding, endocytosis, and recycling of EGF-R mutants. J. Cell Biol. 117:1992;203-212.
20. Honneger A.M.et al. Separate endocytic pathways of kinase defective and active EGF-receptor mutants expressed in the same cells. J. Cell Biol. 110:1990;1541-1548.
21. Lamaze C., Schmid S.L. Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase. J. Cell Biol. 129:1995;47-54.
22. Vieira A.V.et al. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science. 274:1996;2086-2089.
23. Waterman H.et al. Alternative intracellular routing of ErbB receptors may determine signaling potency. J. Biol. Chem. 273:1998;13819-13827.
24. Kranenburg O.et al. Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase. J. Biol. Chem. 274:1999;35301-35304.
25. Wells A.et al. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science. 247:1990;962-964.
26. Worthylake R.et al. ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J. Biol. Chem. 274:1999;8865-8874.
27. Wang Z.et al. Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol. Biol. Cell. 10:1999;1621-1636.
28. Kao A.W.et al. Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling. J. Biol. Chem. 273:1998;25450-25457.
29. Burgess J.W.et al. Intracellular trafficking and processing of ligand-receptor complexes in the endosomal system. Exp. Clin. Endocrinol. 11:1992;67-78.
30. Cohen S., Fava R.A. Internalization of functional epidermal growth factor: receptor/kinase complexes in A-431 cells. J. Biol. Chem. 260:1985;12351-12358.
31. Lai W.H.et al. Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization. J. Cell Biol. 109:1989;2751-2760.
32. Nesterov A.et al. Phosphorylation of the EGF receptor during internalization of A431 cells. Arch. Biochem. Biophys. 313:1994;351-359.
33. DiGuglielmo G.M.et al. Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J. 13:1994;4269-4277.
34. DiGuglielmo G.M.et al. Insulin receptor internalization and signaling. Mol. Cell. Biochem. 182:1998;59-63.
35. Ceresa B.P.et al. Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways. Mol. Cell. Biol. 18:1998;3862-3870.
36. Bevan A.P.et al. Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes. J. Biol. Chem. 272:1997;26833-26840.
37. Wakshull E.M., Wharton W. Stabilized complexes of EGF and its receptor in the cell surface stimulate RNA synthesis but not mitogenesis. Proc. Natl. Acad. Sci. U. S. A. 82:1985;8513-8517.
38. McCune B.K., Earp H.S. The EGF receptor tyrosine kinase in liver epithelial cells: the effect of ligand-dependent changes in cellular location. J. Biol. Chem. 264:1989;15501-15507.
39. Chow J.C.et al. Insulin-like growth factor-1 receptor internalization regulates signaling via the Shc/mitogen-activated protein kinase pathway, but not the insulin receptor substrate-1 pathway. J. Biol. Chem. 273:1998;4672-4680.
40. Haugh J.M.et al. Internalized epidermal growth factor receptors participate in the activation of p21ras in fibroblasts. J. Biol. Chem. 274:1999;34350-34360.
41. McNiven M.A. Dynamin: a molecular motor with pinchase action. Cell. 94:1998;151-154.
42. Altschuler Y.et al. Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms. J. Cell Biol. 143:1998;1871-1881.
43. Lefkowitz R.J. G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and sensitization. J. Biol. Chem. 273:1998;18677-18680.
44. Pitcher J.A.et al. G protein-coupled receptor kinases. Annu. Rev. Biochem. 67:1998;653-692.
45. Goodman O.B.J.et al. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature. 383:1996;447-450.
46. LaPorte S.A.et al. The β2-adrenergic receptor/β-arrestin complex recruits the clathrin adaptor AP-2 during endocytosis. Proc. Natl. Acad. Sci. U. S. A. 96:1999;3712-3717.
47. Luttrell L.M.et al. G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1A fibroblasts. J. Biol. Chem. 272:1997;31648-31656.
48. Daaka Y.et al. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen activated protein kinase. J. Biol. Chem. 273:1998;685-688.
49. Budd D.C.et al. Activation of the mitogen-activated protein kinase pathway by a Gq/11-coupled muscarinic receptor is independent of receptor internalization. J. Biol. Chem. 274:1999;12355-12360.
50. Sarret P.et al. Receptor-mediated internalization is critical for the inhibition of the expression of growth hormone by somatostatin in the pituitary cell line AtT-20. J. Biol. Chem. 274:1999;19294-19300.
51. Whistler J.L., von Zastrow M. Dissociation of functional roles of dynamin in receptor-mediated endocytosis and mitogenic signal transduction. J. Biol. Chem. 274:1999;24575-24578.
52. Yang W.et al. Role of clathrin-mediated endocytosis in CXCR2 sequestration, resensitization, and signal transduction. J. Biol. Chem. 274:1999;11328-11333.
53. Carpenter G. Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J. Cell Biol. 146:1999;697-702.
54. Pierce K.L.et al. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proc. Natl. Acad. Sci. U. S. A. 97:2000;1489-1494.
55. Prenzel N.et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature. 402:1999;884-888.
56. DeGraff J.L.et al. Role of arrestins in endocytosis and signaling of α2-adrenergic receptor subtypes. J. Biol. Chem. 274:1999;11253-11259.
57. Massagué J. TGF-β signal transduction. Annu. Rev. Biochem. 67:1998;753-791.
58. Chen R.H., Derynck R. Homomeric interactions between type II transforming growth factor-beta receptors. J. Biol. Chem. 269:1994;22868-22874.
59. Gilboa L.et al. Oligomeric structure of type I and type II transforming growth factor beta receptors - homodimers form in the ER and persist at the plasma membrane. J. Cell Biol. 140:1998;767-777.
60. Henis Y.I.et al. The types II and III transforming growth factor-beta receptors form homo-oligomers. J. Cell Biol. 126:1994;139-154.
61. Anders R.A., Leof E.B. Chimeric granulocyte/macrophage colony-stimulating factor/transforming growth factor-β (TGF-β) receptors define a model system for investigating the role of homomeric and heteromeric receptors in TGF-β signaling. J. Biol. Chem. 271:1996;21758-21766.
62. Muramatsu M.et al. A chimeric serine/threonine kinase receptor system reveals the potential of multiple type II receptors to cooperate with transforming growth factor-β Mol. Biol. Cell. 8:1997;469-480.
63. Doré J.J.E. Jr. et al. Heteromeric and homomeric transforming growth factor-β receptors show distinct signaling and endocytic responses in epithelial cells. J. Biol. Chem. 273:1998;31770-31777.
64. Anders R.A.et al. Differential requirements for type I and type II TGFβ receptor kinase activity in ligand-mediated receptor endocytosis. J. Biol. Chem. 273:1998;23118-23125.
65. Tsukazaki T.et al. SARA, a FYVE domain protein that recruits smad2 to the TGFβ receptor. Cell. 95:1998;779-791.
66. Stenmark H., Aasland R. FYVE-finger proteins - effectors of an inositol lipid [commentary]. J. Cell Sci. 112:1999;4175-4183.
67. Hocevar B.A.et al. TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J. 18:1999;1345-1356.
68. Sirard C.et al. Targeted disruption in murine cells reveals variable requirement for Smad4 in TGF-β related signaling. J. Biol. Chem. 275:2000;2063-2070.