Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets

Biochemical Journal

Volumn 349, Issue 1, 2000, Pages 231-238

  Hackeng, Christian M ^a   Franke, Barbara ^a   Relou, Ingrid A M ^a   Gorter, Gertie ^a   Bos, Johannes L ^a   Van Rijn, Herman J M ^a   Akkerman, Jan Willem N ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

GTP; Lipid oxidation; Lipoproteins; Thrombocyte; Thromboxane

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 7 [3 [(2 HEPTANAMIDOACETAMIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; GUANOSINE TRIPHOSPHATASE; INDOMETACIN; INTEGRIN; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN;

ARTICLE; CELL GRANULE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; NORMAL HUMAN; PRECIPITATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THROMBOCYTE;

ARACHIDONIC ACID; BLOOD PLATELET DISORDERS; BLOOD PLATELETS; COLLAGEN; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; HUMANS; IMIDAZOLES; INDOMETHACIN; LIGANDS; LIPOPROTEINS, LDL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A; PHOSPHORYLATION; PYRIDINES; RAL GTP-BINDING PROTEINS; RAP1 GTP-BINDING PROTEINS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; THROMBIN; THROMBOXANE A2; TIME FACTORS;

EID: 0034234810     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3490231     Document Type: Article

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