Ras-dependent activation of the small GTPase Ral

Current Biology

Volumn 8, Issue 8, 1998, Pages 471-474

  Wolthuis, Rob M F ^a   Zwartkruis, Fried ^a   Moen, Tessa C ^a   Bos, Johannes L ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0032499175     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(98)70183-6     Document Type: Article

References (20)

1. Bos JL: Ras-like GTPases. Biochim Biophys Acta 1997, 1333:19-33.
2. Wolthuis RMF, de Ruiter ND, Cool RH, Bos JL: Stimulation of gene induction and cell growth by the Ras effector RIf. EMBO J 1997, 22:6748-6761.
3. White MA, Vale T, Camonis JH, Schaefer E, Wigler MH: A role for the RaI guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J Biol Chem 1996, 271:16439-16442.
4. Miller MJ, Prigent S, Kupperman E, Rioux L, Park SH, Feramisco JR, et al.: RaIGDS functions in Ras- and cAMP-mediated growth stimulation. J Biol Chem 1997, 272:5600-5605.
5. Urano T, Emkey R, Feig LA: Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates transformation. EMBO J 1996, 15:810-816.
6. Spaargaren M, Bischoff JR: Identification of the guanine nucleotide dissociation stimulator for RaI as a putative effector molecule of R-ras, K-ras, K-ras and Rap. Proc Natl Acad Sci USA 1994, 91:12609-12613.
7. Kikuchi A, Demo SD, Ye ZH, Chen YW, Williams LT: ralGDS family members interact with the effector loop of ras p21. Mol Cell Biol 1994, 14:7483-7491.
8. Wolthuis RMF, Bauer B, van't Veer LJ, de Vries-Smits AMM, Cool RH, Spaargaren M, et al.: RalGDS-like factor (RIf) is a novel Ras and Rap 1A-associating protein. Oncogene 1996, 13:353-362.
9. Lopez-Barahona M, Bustelo XR, Barbacid M: The TC21 oncoprotein interacts with the RaI guanosine nucleotide dissociation factor. Oncogene 1996, 12:463-470.
10. Murai H, Ikeda M, Kishida S, Ishida O, Okazaki-Kishida M, Matsuura Y, et al.: Characterization of RaI GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral. J Biol Chem 1997, 272:10483-10490.
11. Wolthuis RMF, Franke B, van Triest M, Bauer B, Cool RH, Camonis JH, et al.: Activation of the small GTPase RaI in platelets. Mol Cell Biol 1998, in press.
12. Pronk GJ, Bos JL: The role of p21 ras in receptor tyrosine kinase signalling. Biochim Biophys Acta 1994, 1198:131-147.
13. de Vries-Smits AMM, Burgering BMT, Leevers SJ, Marshall CJ, Bos JL: Involvement of p21 ras in activation of extracellular signal-regulated kinase 2. Nature 1992, 357:602-604.
14. Jiang H, Luo J-Q, Urano T, Frankel P, Lu Z, Foster D, Feig LA: Involvement of RaI GTPase in v-Src-induced phospholipase D activation. Nature 1995, 378:409-412.
15. Feig LA, Urano T, Cantor S: Evidence fora Ras/RaI signaling cascade. Trends Biochem Sci 1996, 21:438-441.
16. Cantor SB, Urano T, Feig LA: Identification and characterization of Ral-binding protein 1, a potential downstream target of RaI GTPases. Mol Cell Biol 1995, 15:4578-4584.
17. Jullien-Flores V, Dorseuil O, Romero F, Letourneur F, Saragosti S, Berger R, et al.: Bridging RaI GTPase to Rho pathways. RLIP76, a RaI effector with CDC42/ Rac GTPase-activating protein activity. J Biol Chem 1995, 270:22473-22477.
18. Park SH, Weinberg RA: A putative effector of RaI has homo logy to Rho/ Rac GTPase activating proteins. Oncogene 1995, 11:2349-2355.
19. de Rooij J, Bos JL: Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras. Oncogene 1997, 14:623-625.
20. ras. Mol Cell Biol 1993, 13:155-162.