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Volumn 37, Issue 1-4, 2000, Pages 39-57

Synthesis of functionalized aza-macrocycles and the application of their metal complexes in binding processes

Author keywords

Aza mucrocycles; Coordinative bonds; Cyclam; Cyclen; Lewis acids; Metal complexes

Indexed keywords


EID: 0034179485     PISSN: 09230750     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1008083528325     Document Type: Article
Times cited : (21)

References (97)
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    • 3. (a) R. S. Dickins, J. A. K. Howard, C. W. Lehmann, J. Moloney, D. Parker and R. D. Peacock: Angew. Chem. 109, 541 (1997); Angew. Chem. Int. Ed. Engl. 36, 521 (1997).
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    • Small amounts of mono-and of trisubstituted products were detected in the reaction mixtures by HPLC. The isomeric disubstituted products could not be separated by column diromatography. The use of more than 2 equiv. of BuLi and electrophile still yields a reaction mixture with isomeric disubstituted compounds as the major products. However, substantial amounts of trisubstituted and small amounts of mono-and tetrasubstituted products were detected
    • 9. Small amounts of mono-and of trisubstituted products were detected in the reaction mixtures by HPLC. The isomeric disubstituted products could not be separated by column diromatography. The use of more than 2 equiv. of BuLi and electrophile still yields a reaction mixture with isomeric disubstituted compounds as the major products. However, substantial amounts of trisubstituted and small amounts of mono-and tetrasubstituted products were detected.
  • 33
    • 0002395536 scopus 로고    scopus 로고
    • Full details of the crystal structure determination (except structure factors) have been deposited under the number 114671 at the Cambridge Crystallographic Data Centre. Copies may be obtained free of charge from: The Director, CCDC, 12 Union Road, GB-Cambridge CB2 1EZ (Telefax: Int. + 1223/336-033: E-mail: deposit@ccdc.cam.ac.uk)
    • 11. Full details of the crystal structure determination (except structure factors) have been deposited under the number 114671 at the Cambridge Crystallographic Data Centre. Copies may be obtained free of charge from: The Director, CCDC, 12 Union Road, GB-Cambridge CB2 1EZ (Telefax: Int. + 1223/336-033: E-mail: deposit@ccdc.cam.ac.uk)
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    • 0002510669 scopus 로고    scopus 로고
    • The less clean Raney-Nickel hydrogenation of disubstituted compounds call for longer reaction times and higher temperatures
    • 12. The less clean Raney-Nickel hydrogenation of disubstituted compounds call for longer reaction times and higher temperatures.
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    • (i) A. Filali, J.-J. Yaouanc and H. Handel: Angew. Chem. 103, 563 (1991); Angew. Chem. Int. Ed. Engl. 30, 560 (1991).
    • (1991) Angew. Chem. Int. Ed. Engl. , vol.30 , pp. 560
  • 66
    • 0031267883 scopus 로고    scopus 로고
    • 22. (a) For a recent review of synthetic and structural aspects of polyaza-macrocycles bearing pendant coordination groups attached to nitrogen, see: K. P. Wainwright, Coord. Chem. Rev. 166, 35 (1997).
    • (1997) Coord. Chem. Rev. , vol.166 , pp. 35
    • Wainwright, K.P.1
  • 68
    • 0002569697 scopus 로고    scopus 로고
    • Full details of the crystal structure determination (except structure factors) have been deposited under the number 106539 at the Cambridge Crystallographic Data Centre. Copies may be obtained tree of charge from: The Director. CCDC, 12 Union Road, GB-Cambridge CB2 1EZ (Telefax: Int. + 1223/336-033: E-mail: deposit@ccdc.cam.ac.uk)
    • 23. Full details of the crystal structure determination (except structure factors) have been deposited under the number 106539 at the Cambridge Crystallographic Data Centre. Copies may be obtained tree of charge from: The Director. CCDC, 12 Union Road, GB-Cambridge CB2 1EZ (Telefax: Int. + 1223/336-033: E-mail: deposit@ccdc.cam.ac.uk)
  • 70
    • 0002396303 scopus 로고    scopus 로고
    • - is achieved in high yield in a simple procedure with acetic acid anhydride and acetic acid avoid ing the toxic Cbz chloride. The amide groups may be converted into tertiary amines by borane reduction, regenerating the full coordination ability of the macrocycle
    • - is achieved in high yield in a simple procedure with acetic acid anhydride and acetic acid avoid ing the toxic Cbz chloride. The amide groups may be converted into tertiary amines by borane reduction, regenerating the full coordination ability of the macrocycle.
  • 71
    • 0343471510 scopus 로고    scopus 로고
    • 26. For an example of preparation of functionalized polyamines on solid phase, see: G. Byk, M. Frederic and D. Seherman: Tetrahedron Lett. 38, 3219 (1997).
    • (1997) Tetrahedron Lett. , vol.38 , pp. 3219
    • Byk, G.1    Frederic, M.2    Seherman, D.3
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    • (c) E. Kimura, T Ikeda, M. Shionoya and M. Shiro: Angew. Chem. 107, 711 (1995); Angew. Chem. Int. Ed. Engl. 34, 663 (1995).
    • (1995) Angew. Chem. Int. Ed. Engl. , vol.34 , pp. 663
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    • 30. (a) Y. Kyogokuy and B. Sul Yu: Bull. Chem. Soc. Jpn. 42, 1387 (1969). Flavins and NAD(P)+ coenzymes are the most important electron transfer agents in biology. Moreover, several artificial receptors to intercept the photochemisty of flavins have been described in the literature:
    • (1969) Bull. Chem. Soc. Jpn. , vol.42 , pp. 1387
    • Kyogokuy, Y.1    Sul Yu, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.