Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells

Journal of Immunology

Volumn 164, Issue 5, 2000, Pages 2728-2737

  Shinohara, Hisashi ^a   Yano, Seiji ^a   Bucana, Corazon D ^a   Fidler, Isaiah J ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER IMMUNOLOGY; COLON CANCER; CYTOLYSIS; GRANULOCYTE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0034163565     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2728     Document Type: Article

References (53)

1. Wahl, L. M., and H. K. Kleinman. 1998. Tumor-associated macrophages as targets for cancer therapy. J. Natl. Cancer Inst. 90:1583.
2. Eigen, K. D., D. G. Alleva, and D. W. Mullins. 1998. Tumor-induced immune dysfunction: the macrophage connection. J. Leukocyte Biol. 64:275.
3. Fidler, I. J. 1985. Macrophages and metastasis: a biological approach to cancer therapy. Cancer Res. 45:4714.
4. Fidler, I. J. 1994. Therapy of cancer metastasis by systemic activation of macrophages. Adv. Pharmacol. 30:271.
5. Gasson, J. C. 1991. Molecular physiology of granulocyte-macrophage colony-stimulating factor. Blood 77:1131.
6. Hill, A. D., H. A. Naama, S. E. Calvano, and J. M. Daly. 1995. The effect of granulocyte-macrophage colony stimulating factor on myeloid cells and its clinical applications. J. Leukocyte Biol. 58:634.
7. Simons, J. W., E. M. Jaffee, C. E. Weber, H. I. Levitsky, W. G. Nelson, M. A. Carducci, A. J. Lazenby, L. K. Cohen, C. C. Finn, S. M. Clift, et al. 1997. Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Res. 57:1537.
8. Soiffer, R., T. Lynch, M. Mihm, K. Jung, C. Rhuda, J. C. Schmollinger, F. S. Hodi, L. Liebster, P. Lam, S. Mentzer, et al. 1998. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc. Natl. Acad. Sci. USA 95:13141.
9. Berns, A. J., S. Clift, L. K. Cohen, R. C. Donehower, G. Dranoff, K. M. Hauda, E. M. Jaffee, A. J. Lazenby, H. I. Levitsky, F. F. Marshall, et al. 1995. Phase I study of nonreplicating autologous tumor cell injections using cells prepared with or without GM-CSF gene transduction in patients with metastatic renal cell carcinoma. Hum. Gene Ther. 6:347.
10. Dranoff, G., E. Jaffee, A. Lazenby, P. Golumbek, H. Levitsky, K. Brose, V. Jackson, H. Hamada, D. Pardoll, and R. C. Mulligan. 1993. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad Sci. USA 90:3539.
11. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693.
12. Botella, R., M. D. Sarradet, L. E. Potter, M. Lawley, T. H. Galloway, J. C. Ansel, and C. A. Armstrong. 1998. Inhibition of murine melanoma growth by granulocyte-macrophage colony stimulating factor gene transfection is not haplotype-specific. Melanoma Res. 8:245.
13. Lee, C. T., S. Wu, I. F. Ciernik, H. Chen, S. Nadaf-Rahrov, D. Gabrilovich, and D. P. Carbone. 1997. Genetic immunotherapy of established tumors with adenovirus-murine granulocyte-macrophage colony-stimulating factor. Hum. Gene Ther. 8:187.
14. Armstrong, C. A., R. Botella, T. H. Galloway, N. Murray, J. M. Kramp, I. S. Song, and J. C. Ansel. 1996. Antitumor effects of granulocyte-macrophage colony-stimulating factor production by melanoma cells. Cancer Res. 56:2191.
15. Dong, Z., J. Yoneda, R. Kumar, and I. J. Fidler. 1998. Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 188:755.
16. Oppenheim, J. J., C. O. Zachariae, N. Mukaida, and K. Matsushima. 1991. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Anna. Rev. Immunol. 9:617.
17. Rollins, B. J. 1997. Chemokines. Blood 90:909.
18. Wolpe, S. D., G. Davatelis, B. Sherry, B. Beutler, D. G. Hesse, H. T. Nguyen, L. L. Moldawer, C. F. Nathan, S. F. Lowry, and A. Cerami. 1988. Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J. Exp. Med. 167:570.
19. Matsushima, K., C. G. Larsen, G. C. DuBois, and J. J. Oppenheim. 1989. Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. J. Exp. Med. 169:1485.
20. Pace, J. L., and S. W. Russell. 1981. Activation of mouse macrophages for tumor cell killing. I. Quantitative analysis of interactions between lymphokine and lipopolysaccharide. J. Immunol. 126:1863.
21. Killion, J. J., and I. J. Fidler. 1998. Therapy of cancer metastasis by tumoricidal activation of tissue macrophages using liposome-encapsulated immunomodulators. Pharmacol. Ther. 78:141.
22. Shinohara, H., J. J. Killion, H. Kuniyasu, R. Kumar, and I. J. Fidler. 1998. Prevention of intestinal toxic effects and intensification of irinotecan's therapeutic efficacy against murine colon cancer liver metastases by oral administration of the lipopeptide JBT 3002. Clin. Cancer Res. 4:2053.
23. Rollins, B. J., and M. E. Sunday. 1991. Suppression of tumor formation in vivo by expression of the JE gene in malignant cells. Mol. Cell. Biol. 11:3125.
24. Singh, R. K., K. Berry, K. Matsushima, K. Yasumoto, and I. J. Fidler. 1993. Synergism between human monocyte chemotactic and activating factor and bacterial products for activation of tumoricidal properties in murine macrophages. J. Immunol. 151:2786.
25. Huatig, S., R. K. Singh, K. Xie, M. Gutman, K. K. Berry, C. D. Bucana, I. J. Fidler, and M. Bar-Eli. 1994. Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells. Cancer Immunol. Immunother. 39:231.
26. Grabstein, K. H., D. L. Urdal, R. J. Tushinski, D. Y. Mochizuki, V. L. Price, M. A. Cantrell, S. Gillis, and P. J. Conlon. 1986. Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factor. Science 232:506.
27. Sugaya, M., M. Tagawa, H. Matsubara, Y. Gunji, K. Takenaga, T. Maeda, Y. Koide, T. Asano, T. Ochiai, K. Isono, and S. Sakiyama. 1998. Induction of antitumor effect on human esophageal carcinoma cells by the retroviral expression of granulocyte macrophage-colony stimulating factor gene. Int. J. Oncol. 12:321.
28. Morikawa, K., S. M. Walker, M. Nakajima, S. Pathak, J. M. Jessup, and I. J. Fidler. 1988. Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res. 48:6863.
29. Takahashi, Y., C. D. Bucana, W. Liu, J. Yoneda, Y. Kitadai, K. R. Cleary, and L. M. Ellis. 1996. Platelet-derived endothelial cell growth factor in human colon cancer angiogenesis: role of infiltrating cells. J. Wall. Cancer Inst. 88:1146.
30. Saiki, I., L. Milas, N. Hunter, and I. J. Fidler. 1986. Treatment of experimental lung metastasis with local thoracic irradiation followed by systemic macrophage activation with liposomes containing muramyl tripeptide. Cancer Res. 46:4966.
31. Adams, J. L., C. J. Battjes, and D. A. Buthala. 1987. Biological specimen preparation for SEM by a method other than critical point drying. In Proceedings of the 45th Annual Meeting of Electron Microscopy Society of America. G. W. Bailey, ed. San Francisco Press, San Francisco, p. 956.
32. Radinsky, R., P. M. Kraemer, M. A. Raines, H. J. Xung, and L. A. Culp. 1987. Amplification and rearrangement of Kristen-ras oncogene in virus-transformed BALB/c 3T3 cells during malignant tumor progression. Proc. Natl. Acad. Sci. USA 84:5143.
33. Davatelis, G., P. Tekamp-Olson, S. D. Wolpe, K. Hermsen, C. Luedke, C. Gallegos, D. Coit, J. Merryweather, and A. Cerami. 1988. Cloning and characterization of a cDNA for murine macrophage inflammatory protein (MIP), a novel monokine with inflammatory and chemokinetic properties. J. Exp. Med. 167:1939.
34. Fort, P., L. Morty, M. Piechaczyk, S. E. Sabrouty, C. Dani, P. Jeanteur, and J. M. Blanchard. 1985. Various rat adult tissues express only one major mRNA species from the glyceraldehyde 3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res. 13:1431.
35. Rollins, B. J., E. D. Morrison, and C. D. Stiles. 1988. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc. Natl. Acad. Sci. USA 85:3738.
36. Shapiro, S. D., G. L. Griffin, D. J. Gilbert, N. A. Jenkins, N. G. Copeland, H. G. Welgus, R. M. Senior, and T. J. Ley. 1992. Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase. J. Biol. Chem. 267:4664.
37. Jiang, Y., D. I. Beller, G. Frendl, and D. T. Graves. 1992. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J. Immunol. 148:2423.
38. Vaddi, K., and R. C. Newton. 1994. Regulation of monocyte integrin expression by family chemokines. J. Immunol. 153:4721.
39. + dendritic cells and tartrate-resistant acid phosphatase-positive osteoclast-like multinucleated giant cells from human monocytes. Blood 88:4029.
40. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693.
41. Romani, N., D. Reider, M. Heuer, S. Ebner, E. Kampgen, B. Eible, D. Niederwieser, and G. Schuler. 1994. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180:83.
42. Kumar, R., J. Yoneda, I. J. Fidler, and Z. Dong. 1999. GM-CSF-transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages and poorly tumorigenic in immune compromised mice. J. Leukocyte Biol. 65:102.
43. Fu, Y. X., G. A. Watson, M. Kasahara, and D. M. Lopez. 1991. The role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma. I. Induction of regulatory macrophages in normal mice by the in vivo administration of rGM-CSF. J. Immunol. 146:783.
44. Hershkoviz, R., L. Gahalon, D. Gilat, S. Milon, A. Miller, and O. Lider. 1993. Physically damaged extracellular matrix induces TNF-α secretion by interacting with resting CD4 T cells and macrophages. Scand. J. Immunol. 37:111.
45. Mantovani, A., W. J. Ming, C. Balotta, B. Abdeljalil, and B. Bottazzi. 1986. Origin and regulation of tumor-associated macrophages: the role of tumor-derived chemotactic factor. Biochem. Biophys. Acta 865:59.
46. Carr, M. W., S. J. Roth, E. Luther, S. S. Rose, and T. A. Springer. 1994. Monocyle chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc. Natl. Acad. Sci. USA 91:3652.
47. Roberge, C. J., S. R. McColl, B. Larochelle, and J. Gosselin. 1998. Granulocyte-macrophage colony-stimulating factor enhances EBV-induced synthesis of chemotactic factors in human neutrophils. J. Immunol. 160:2442.
48. McColl, S. R., and I. Clark-Lewis. 1999. Inhibition of murinc neutrophil recruitment in vivo by CXC chemokine receptor antagonists. J. Immunol. 163:2829.
49. Bozic, C. R., L. F. Kolakowski, Jr., N. P. Gerald, C. Garcia-Rodriguez, C. von Uexkull-Guldenband, M. J. Conklyn, R. Breslow, H. J. Showell, and C. Gerard. 1995. Expression of biologic characterization of the murine chemokine KC. J. Immunol. 154:6048.
50. Frevert, C. W., A. Farone, H. Danaee, J. D. Paulauskis, and L. Kobzik. 1995. Functional characterization of rat chemokine macrophage inflammatory protein-2. Inflammation 19:133.
51. Arnaout, M. A. 1990. Structure and function of the leukocyte adhesion molecules CD11/CD18. Blood 75:1037.
52. Kumar, R., Z. Dong, and I. J. Fidler. 1996. Differential regulation of metalloelastase activity in niurine peritoneal macrophages by granulocyte-macrophage (GM-CSF) and macrophage colony-stimulating factor (M-CSF). J. Immunol. 157:5104.
53. Dong, Z., R. Kumar, X. Yang, and I. J. Fidler. 1997. Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell 88:801.