Differential Regulation of Metalloelastase Activity in Murine Peritoneal Macrophages by Granulocyte-Macrophage Colony-Stimulating Factor and Macrophage Colony-Stimulating Factor

Journal of Immunology

Volumn 157, Issue 11, 1996, Pages 5104-5111

  Kumar, Rakesh ^a   Dong, Zhongyun ^a   Fidler, Isaiah J ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE; LIPOPOLYSACCHARIDE; MACROPHAGE ELASTASE; MESSENGER RNA; METALLOPROTEINASE; RECOMBINANT GAMMA INTERFERON; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; COMPARATIVE STUDY; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; IN VITRO STUDY; METABOLISM; MOUSE; PERITONEUM MACROPHAGE; UPREGULATION;

ANIMALS; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; INTERFERON-GAMMA, RECOMBINANT; LIPOPOLYSACCHARIDES; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES, PERITONEAL; MATRIX METALLOPROTEINASE 12; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; RNA, MESSENGER; UP-REGULATION;

EID: 0030469388     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (79)

1. Werb, Z. 1989. Proteinases and matrix degradation. In Textbook of Rheumatology, 3rd Ed. W. N. Kelly, E. D. Harris, S. Ruddy, and C. B. Sledge, eds. W. B. Saunders, Philadelphia, p. 300.
2. Adams, D. O., and T. A. Hamilton. 1988. Phagocytic cells: cytotoxic activities of macrophages. In Inflammation: Basic Principles and Clinical Correlates. J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds. Raven Press, New York, p. 471.
3. Fidler, I. J. 1994. Therapy of cancer metastasis by systemic activation of macrophages. Adv. Pharmacol. 30:271.
4. Cury, J. D., E. J. Campbell, C J. Lazarus, R. J. Albin, and H. G. Welgus. 1988. Selective upregulation of human alveolar macrophage collagenase production by lipopolysaccharide and comparison to collagenase production by fibroblasts. J. Immunol. 141:4306.
5. Welgus, H. G., E. J. Campbell, J. D. Cury, A. Z. Eisen, R. M. Senior, S. M. Wilhelm, and G. I. Goldberg. 1990. Neutral metalloproteinases produced by human mononuclear phagocytes: enzyme profile, regulation, and expression during cellular development. J. Clin. Invest. 86:1494.
6. Campbell, E. J., J. M. Cury, S. D. Shapiro, G. I. Goldberg, and H. G. Welgus. 1991. Neutral proteinases of human mononuclear phagocytes, cellular differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinases. J. Immunol. 146:1286.
7. Hibbs, M. S., J. R. Hoidal, and A. J. Kang. 1987. Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages. J. Clin. Invest. 80:1644.
8. Xie, B., Z. Dong, and I. J. Fidler. 1994. Regulatory mechanisms for the expression of type IV collagenases/gelatinases in murine macrophages. J. Immunol. 152:3637.
9. Werb, Z., and S. Gordon. 1975. Elastase secretion by stimulated macrophages: characterization and regulation. J. Exp. Med. 142:361.
10. White, R., H.-S. Lin, and C. Kuhn. 1977. Elastase secretion by peritoneal exudative and alveolar macrophages. J. Exp. Med. 146:802.
11. Shapiro, S. D. 1994. Elastolytic metalloproteinases produced by human mononuclear phagocytes-potential role in destructive lung disease. Am. J. Respir. Crit. Care Med. 150:5160.
12. Senior, R. M., N. L. Connolly, J. D. Cury, H. G. Welgus, and E. J. Campbell. 1989. Elastin degradation by human alveolar macrophages: a prominent role of metalloproteinase activity. Am. Rev. Respir. Dis. 139:1251.
13. Banda, M. J., and Z. Werb. 1981. Mouse macrophage elastase: purification and characterization as a metalloproteinase. Biochem. J. 193:589.
14. Mignatti, P., E. Robbins, and D. B. Rifkin. 1986. Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade. Cell 47:487.
15. Khokha, R., P. Waterhouse, S. Yagel, P. K. Lale, C. M. Overall, G. Norton, and D. T. Denhardt. 1989. Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3. Science 243:947.
16. Basset, P., J. P. Bellocq, C. Wolf, I. Stoll, J. M. Limacher, O. L. Podhajeer, M. P. Chenard, M. C. Rio, and P. Chambon. 1990. A novel metalloproteinase gene specifically expressed: stromal cells of breast carcinomas. Nature 348:699.
17. Dean, D. D., J. Martel-Pelleier, J. P. Pelleter, D. S. Howell, and J. F. Woessner, Jr. 1989. Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. J. Clin. Invest. 84:678.
18. Henney, A. M., P. R. Wakely, M. J. Davies, K. Foster, R. Henbry, G. Murphy, and S. Humphries. 1991. Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. Proc. Natl. Acad. Sci. USA 88:815.
19. Woessner, J. F., Jr. 1991. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5:2146.
20. Campbell, E. J., J. D. Cury, C. J. Lazarus, and H. G. Welgus. 1987. Monocyte procollagenase and tissue inhibitor of metalloproteinase: identification, characterization, and regulation of secretion. J. Biol. Chem. 262:15862.
21. Shapiro, S. D., D. K. Kobayashi, and H. G. Welgus. 1992. Identification of TIMP-2 in human alveolar macrophages: regulation of biosynthesis is opposite to that of metalloproteinases and TIMP-1. J. Biol. Chem. 267:13890.
22. Welgus, H. G., R. M. Senior, W. C. Parks, A. J. Kahn, T. J. Ley, S. D. Shapiro, and E. J. Campbell. 1992. Neutral proteinase expression by human mononuclear phagocytes: a prominent role of cellular differentiation. Matrix (Suppl. 1):363.
23. Shotton, D. M., and B. S. Hartley. 1970. Amino acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature 225:802.
24. Ohlsson, K., and I. Olsson. 1974. The neutral proteases of human granulocytes: isolation and partial characterization of granulocyte elastase. Eur. J. Biochem. 42:519.
25. Sottrup-Jensen, L., H. Claeys, M. Zajdel, T. E. Petersen, and S. Magnusson. 1978. The primary structure of human plasminogen: isolation of two lysine-binding fragments and one "mini-plasminogen" (M. W. 38,000) by elastase-catalyzed-specific limited proteolysis. Prog. Chem. Fibrinolysis Thrombolysis 3:191.
26. Bar-Schavit, Z., S. L. Teitelbaum, G. P. Sticklin, A. Z. Eisen, A. J. Kahn, and H. G. Welgus. 1985. Differentiation of a human leukemia cell line and expression of collagenase inhibitor. Proc. Natl. Acad. Sci. USA 82:5380.
27. Welgus, H. G., N. L. Connolly, and R. M. Senior. 1986. 12-O-Tetra-decanoylphorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases: high levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G. J. Clin. Invest. 77:1675.
28. Shapiro, S. D., E. J. Campbell, D. K. Kobayashi, and H. G. Welgus. 1990. Immune modulation of metalloproteinase production in human macrophages: selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by IFN-γ. J. Clin. Invest. 86:1204.
29. Shapiro, S. D., E. J. Campbell, D. K. Kobayashi, and H. G. Welgus. 1991. Dexamethasone selectively modulates basal and lipopolysaccharide-induced metalloproteinase and tissue inhibitor of metalloproteinase production by human alveolar macrophages. J. Immunol. 146:2724.
30. Dudon, M. D., and S. N. Vogel. 1985. Analysis of effects of lipopolysaccharide and interferon on murine macrophages: modulation of elastase secretion in vitro. Infect. Immunol. 49:709.
31. Saiki, I., and I. J. Fidler. 1985. Synergistic activation by recombinant mouse IFN-γ and muramyl dipeptide of tumoricidal properties in mouse macrophages. J. Immunol. 135:684.
32. Banda, M., Z. Werb, and J. H. McKerrow. 1987. Elastin degradation. Methods Enzymol. 144:288.
33. Senior, R. M., G. L. Griffin, C. J. Fliszar, S. D. Shapiro, G. I. Goldberg, and H. G. Welgus. 1991. Human 92- and 72-kilodalton type IV collagenases are elastases. J. Biol. Chem. 266:7870.
34. Ding, A., C. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J. Immunol. 141:2407.
35. Radinsky, R., P. M. Kraemer, M. A. Raines, H. J. Xung, and L. A. Culp. 1987. Amplification and rearrangement of Kristen ras oncogene in virus transformed BALB/3T3 cells during malignant tumor progression. Proc. Natl. Acad. Sci. USA 84:5143.
36. Fort, P., L. Morty, M. Piechaczyk, S. E. Sabrouty, C. Dani, P. Jeanteur, and J. M. Blanchard. 1985. Various rat adult tissues express only one major mRNA species from the glyceraldehyde 3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res. 13:1431.
37. Shapiro, S. D., G. L. Griffin, D. J. Gilbert, N. A. Jenkins, N. G. Copeland, H. G. Welgus, R. M. Senior, and T. J. Ley. 1992. Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase. J. Biol. Chem. 267:4664.
38. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6.
39. Sessa, W. C., J. K. Harrison, C. M. Barber, D. Zeng, M. E. Durieux, D. D. D'Angelo, K. R. Lynch, and M. J. Peach. 1992. Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase. J. Biol. Chem. 267: 15274.
40. Weisz, A., S. Oguchi, L. Cicatiello, and H. Esumi. 1994. Dual mechanism for the control of inducible-type NO synthase gene expression in macrophages during activation by interferon-γ and bacterial lipopolysaccharide. J. Biol. Chem. 269: 8324.
41. Barrett, A. J. 1977. Introduction to the history and classification of tissue proteinases. In Proteinases in Mammalian Cells and Tissues. A. J. Barrett, ed. North-Holland Publishing Co., Amsterdam, p. 1.
42. Knight, C. G. 1977. Principles of the design and use of synthetic substances and inhibitors for tissue proteinases. In Proteinases in Mammalian Cells and Tissues. A. J. Barrett, ed. North-Holland Publishing, Co., Amsterdam, p. 583.
43. Barrett, A. J. 1994. Classification of peptidases. Methods Enzymol. 244:1.
44. Stuehr, D. J., and C. F. Nathan. 1989. Nitric oxide: a macrophage product for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med. 169:1543.
45. Nathan, C. F. 1982. Secretion of oxygen intermediates: role in effector functions of activated macrophages. Fed. Proc. 41:2206.
46. Schreck, R., P. Rieber, and P. A. Baeuerle. 1991. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-xB transcription factor and HIV-1. EMBO J. 10:2247.
47. Moncade, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43:109.
48. Stuehr, D. J., and O. W. Griffith. 1992. Mammalian nitric oxide synthase. In Advances in Enzymology and Related Areas of Molecular Biology, Vol. 65. A. Meister, ed. Wiley-Interscience, New York, p. 287.
49. Hibbs, J. B., Jr., R. R. Taintor, and Z. Vavrin. 1987 Macrophage cytotoxicity: role for L-arginine deiminase activity and amino nitrogen to nitrate. Science 235: 473.
50. Blake, D. R., R. E. Allen, and J. Lunec. 1987. Free radicals in biological systems: a review orientated to inflammatory processes. Br. Med. Bull. 43:371.
51. Cheeseman, K. H., and T. F. Slater. 1993. An introduction to free radical biochemistry. Br. Med. Bull. 49:481.
52. Brach, M. A., and F. Herrman. 1991. Haematopoietic growth factor interactions and regulation of production. Acta Haematol. 86:128.
53. Crosier, P. S., and S. C. Clark. 1992. Basic biology of the hematopoietic growth factors. Semin. Oncol. 19:349.
54. Metcalf, D. 1990. The colony stimulating factors. Cancer 65:2185.
55. Chen, B. D., C. R. Clark, and T. Chon. 1988. Granulocyte-macrophage colony stimulating factor stimulates monocyte and tissue macrophage proliferation and enhances their responsiveness to macrophage colony stimulating factor. Blood 71:997.
56. Sampson-Johannes, A., and J. A. Cerlino. 1988. Enhancement of human monocyte tumoricidal activity by recombinant M-CSF. J. Immunol. 1-41:3680.
57. Docherty, A. J., A. Lyons, B. J. Smith, E. M. Wright, P. E. Stephens, T. J. Harris, G. Murphy, and J. J. Reynolds. 1985. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318: 66.
58. Vodvotz, Y., C. Bogdan, J. Paik, Q. Xie, and C. Nathan. 1993. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor-β. J. Exp. Med. 178:605.
59. Fidler, I. J. 1995. Modulation of the organ microenvironment for treatment of cancer metastasis. J. Natl. Cancer Inst. 87:1588.
60. Nakajima, M., K. Morikawa, A. Fabra, C. D. Bucana, and I. J. Fidler. 1990. Influence of the organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J. Natl. Cancer Inst. 82:1890.
61. Devlin, J. J., P. E. Devlin, K. Myambo, M. B. Lilly, T. A. Rado, and M. K. Warren. 1987. Expression of granulocyte colony-stimulating factor by human cell lines. J. Leukocyte Biol. 41:302.
62. Fu, Y., G. Watson, J. J. Jimenez, Y. Wang, and D. M. Lopez. 1990. Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor. Cancer Res. 50:227.
63. Nakamura, M., S. Merchav, A. Carter, A., T. J. Ernst, G. D. Demetri, Y. Furukawa, K. Anderson, A. S. Freedman, and J. D. Griffin. 1989. Expression of a novel 3.5-kb macrophage colony-stimulating factor transcript in human myeloma cells. J. Immunol. 143:3543.
64. Ramakrishnan, S., J. Xu, S. J. Brandt, J. E. Niedel, R. C. Bast, Jr., and E. L. Brown. 1989. Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines. J. Clin. Invest. 83:921.
65. Tsuchiya, Y., M. Igarashi, R. Suzuki, and K. Kumagai. 1988. Production of colony-stimulating factor by tumor cells and the factor-mediated induction of suppressor cells. J. Immunol. 141:699.
66. Young, M. R., S. Aquino, and M. E. Young. 1989. Differential induction of hematopoiesis and immune suppressor cells in the bone marrow versus in the spleen by Lewis lung carcinoma variants. J. Leukocyte Biol. 45:262.
67. Joraschkewitz, M., H. Depenbrock, M. Freund, G. Erdmann, H.-J. Meyer, W. DeRiese, D. Nenkem, V. Hanauske, M. Krumwieh, H. Poliwade, and A.-R. Hanaciske. 1992. Effects of cytokines on in vitro colony formation of primary human tumor specimens. Eur. J. Cancer 26:1070.
68. Foulke, R. S., M. H. Marshall, P. P. Trotta, and D. D. Von Hoff. 1990. In vitro assessment of the effects of granulocyte-macrophage colony-stimulating factor on primary human tumors and derived lines. Cancer Res. 50:6264.
69. Kohn, E. C., G. H. Hollister, J. D. DiPersio, S. Wahl, L. A. Liotta, and E. Schiffman. 1993. Granulocyte-macrophage colony-stimulatory factor induces human melanoma-cell migration. Int. J. Cancer 53:968.
70. Young, M. R. I., Y. Lozano, M. Coogan, M. A. Wright, M. E. Young, and J. M. Bagash. 1992. Stimulation of the metastatic properties of Lewis lung carcinoma cells by autologous granulocyte-macrophage colony-stimulating factor. Int. J. Cancer 50:628.
71. O'Reilly, M. S., L. Holmgren, Y. Shing, C. Chen, R. A. Rosenthal, A. Moses, W. S. Lane, Y. Cao, E. H. Sage, and J. Folkman. 1994. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79:315.
72. Matrisian, L. M. 1990. Metalloproteinases and their inhibitors in matrix remodelling. Trends Genet. 6:121.
73. Angel, P., I. Baumann, B. Stein, H. Delois, H. J. Rahmsdorf, and P. Herrlich. 1987. 12-O-Tetradecanoyphorbol-13-acetate induction of the human collagenase-1 gene is mediated by an inducible enhancer element located in the 5′-flanking region. Mol. Cell Biol. 7:2256.
74. Kerr, L. D., D. B. Miller, and L. M. Matrisian. 1990. TGF-β1 inhibition of trasin/stromelysin gene expression is mediated through a fos binding sequence. Cell 61:267.
75. Birkeal-Hansen, H., W. G. I. Moore, M. K. Bodden, L. J. Windsor, B. Birkedal-Hansen, A. DeCarlo, and J. A. Engler. 1993. Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med. 4:197.
76. Murphy, G., and A. J. P. Docherty. 1992. The matrix metalloproteinases and their inhibitors. Am. J. Resp. Cell Mol. Biol. 7:120.
77. Testa, J. E., and J. P. Quigley. 1991. Reversal of misfortune: TIMP-2 inhibits tumor cell invasion. J. Natl. Cancer Inst. 83:740.
78. Albini, A., A. Melchiori, L. Santi, L. A. Liotta, P. D. Brown, and W. G. Stetler-Stevenson. 1991. Tumor cell invasion inhibited by TIMP-2. J. Natl. Cancer Inst. 83:775.
79. DeClerck, Y. A., T.-D. Yean, D. Chan, H. Shimada, and K. E. Langley. 1991. Inhibition of tumor cell invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor. Cancer Res. 51:2151.