GM-CSF-transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages and poorly tumorigenic in immune-compromised mice

Journal of Leukocyte Biology

Volumn 65, Issue 1, 1999, Pages 102-108

  Kumar, Rakesh ^a   Yoneda, Junya ^a   Fidler, Isaiah J ^a   Dong, Zhongyun ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Cytotoxicity; Tumorigenicity

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOLOGY; CARCINOGENESIS; FEMALE; IMMUNE DEFICIENCY; MACROPHAGE; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0032924592     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.65.1.102     Document Type: Article

References (47)

1. Gasson. J. C., Weisbart, R. H., Kaufman, S. E., Clark, S. C., Hewick, R. M., Wong, G. G., Golde, D. W. (1984) Purified human granulocyte-macrophage colony-stimulating factor direct action on neutrophils. Science 226, 1339-1342.
2. Horiguchi, J., Warren, M. K., Kufe, D. (1987) Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor. Blood 69, 1259-1261.
3. Burgess, A. W., Metcalf, D. (1980) The nature and action of granulocyte-macrophage colony-stimulating factors. Blood 56, 947-958.
4. Gough, N. M., Nicola, N. A. (1990) Granulocyte-macrophage colony-stimulating factor. In Colony-Stimulating Factors: Molecular and Cellular Biology (T. M. Dexter, J. M. Garland, N. G. Testa, eds.) New York: Marcel Dekker, 111-153.
5. Brandt, S. J., Peters, W. P., Atwater, S. K., Kurtzberg, J., Borowitz, M. J., Jones, R. B., Shpall, E. J., Bast, R. C., Jr., Gilbert, C. J., Odette, D. H. (1988) Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow transplantation. N. Engl. J. Med. 318, 869-876.
6. Vadhan-Raj, S., Keating, M., LeMaistre, A., Hittelman, W. N., McCredie, K., Trujillo, J. M., Broxmeyer, H. F., Henney, C., Gutterman, J. U. (1987) Effect of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes. N. Engl. J. Med. 317, 1545-1552.
7. Groopman, J. E., Mitsuyasu, R. T., de Leo, M. J., Odette, D. H., Golde, D. W. (1987) Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome. N. Engl. J. Med. 317, 593-598.
8. Antman, K. S., Griffin, J. D., Elias, A., Socinski, M. A., Ryan, L., Cannistra, S. A., Oette, D., Whitley, M., Frei, E., III. Schnipper, L. E. (1988) Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. N. Engl. J. Med. 319, 593-598.
9. Weisbart, R. H., Golde, D. W. Clark, C. C., Wong, G. G., Gasson, J. C. (1985) Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. Nature 314, 361-363.
10. Lopez, A. F., Williamson, D. J., Gamble, J. R., Begley, C. G., Harlan, J. M., Klebanoff, S. J., Waltersdorph, A., Wong, G., Clark, S., C. Vadas, M. A. (1986) Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression and survival. J. Clin. Invest. 78, 1220-1228.
11. Aranout, M. A., Wang, E. A., Clark, S. C., Sieff, C. A. (1986) Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes. J. Clin. Invest. 78, 597-601.
12. Fischer, H. G., Frosch, S., Reske, K., Reske-Kunz, A. B. (1988) Granulocyte-macrophage colony-stimulating factor activates macrophages derived from bone marrow cultures to synthesis of MHC class II molecules and to augmented antigen presentation function. J. Immunol. 141, 3882-3888.
13. Cicco, N. A., Lindemann, A., Content, J., Vandenbussche, P., Lubbert, M., Gauss, J., Mertelsmann, R., Hermann, F. (1990) Inducible production of interleukin-6 by human polymorphonuclear neutrophils: role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α. Blood 75, 2049-2052.
14. Granstein, K. H., Urdal, D. L., Tushinski, R. J., Mochizuku, D. Y., Price, V. L., Cantreli, M. A., Gillis, S., Conlon, P. J. (1986) Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factor. Science 232, 506-508.
15. Sisson, S. D., Dinarello, C. A. (1988) Production of interleukin-1α and interleukin-1β and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor. Blood 72, 1368-1374.
16. Cannistra, S. A., Rambaldi, A., Spriggs, D. R., Herrman, F., Kufe, D., Griffin, J. D. (1987) Human granulocyte-macrophage colony-stimulating factor induces expression of the tumor necrosis factor gene by the U937 cell line and by normal human monocytes. J. Clin. Invest. 79, 1720-1728.
17. 2. J. Immunol. 143, 1189-1205.
18. Brissette, W. H., Baker, D. A., Stam, E. J., Umland, J. P., Griffiths, R. J. (1995) GM-CSF rapidly primes mice for enhanced cytokine production in response to LPS and TNF. Cytokine 7, 291-295.
19. Basu, S., Dunn, A. R., Marino, M. W., Savoia, H., Hodgson, G., Lieschke, G. L., Cebon, J. (1997) Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice. J. Immunol. 159, 1412-1417.
20. Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H., Pardoll, D., Mulligan, R. C. (1993) Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting antitumor immunity. Proc. Natl. Acad. Sci. USA 90, 3539-3543.
21. Saito, S., Bennerji, R., Gransbacher, B., Rosenthal, F. M., Romanenko, P., Heston, W. D. W., Fair, W. R., Gilboa, E. (1994) Immunotherapy of bladder cancer with cytokine gene-modified tumor vaccines. Cancer Res. 54, 3516-3520.
22. Vieweg, J., Rosenthal, F. M., Bannerji, R., Heston, W. D. W., Fair, W. R., Gansbacher, B., Gilboa, E. (1994) Immunotherapy of prostate cancer in the Dunning rat model: use of cytokine gene modified tumor vaccines. Cancer Res. 54, 1760-1765.
23. Armstrong, C. A., Botella, R., Galloway, T. H., Murray, N., Kramp, J. M., Song, I. S., Ansel, J. C. (1996) Antitumor effects of granulocyte-macrophage colony-stimulating factor production by melanoma cells. Cancer Res. 56, 2191-2198.
24. McLaughlin, J. P., Abrams, S., Kantor, J., Dobzranski, M. J., Greenbaum, J., Schlom, J., Greiner, J. W. (1997) Immunization with a syngeneic tumor infected with recombinant vaccinia virus expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) induces tumor regression and long-lasting systemic immunity. J. Immunother. 20, 449-459.
25. Wang, J., Wei, S.-J., Yang, W. K., Lin, W.-C., Yang, D.-M., Whang-Peng, J., Ting, C.-C. (1996) In vitro and in vivo correlation of the effect of granulocyte-macrophage colony-stimulating factor gene transfer on the tumorigenicity and immunogenicity of B16 melanoma. Int. J. Oncol. 9, 1267-1276.
26. Grabbe, S., Bruvers, S., Gallo, F. L., Kinsley, T. L., Nazareno, R., Granstein, R. D. (1991) Tumor antigen presentation by murine epidermal cells. J. Immunol. 146, 3656-3661.
27. Tazi, A., Bouchonnet, F., Grandsaigne, M., Boumsell, L., Hance, A. J., Soler, O. (1993) Evidence that granulocyte-macrophage colony-stimulating factor regulates the distribution and differentiated state of dendritic cells: Langerhans cells in human lung and lung cancer. J. Clin. Invest. 91, 566-576.
28. Berns, A. J. M., Clift, S., Cohen, L. K., Donehover, R. C., Dranoff, G., Hauda, K. M., Jaffee, E. M., Lazenby, A. J., Levitskt, H. I., Marshall, F. F., Mulligan, R. C., Nelson, W. G., Owen, A. H., Pardoll, D. M., Parry, G., Partin, A. H., Piantadosi, S., Simons, J. W., Zabora, J. R. (1995) Phase I study of nonreplicating autologous tumor cell injections using cells prepared with ur without GM-CSF gene transduction in patients with metastatic renal cell carcinoma. Hum. Gene Ther. 6, 347-368.
29. Dong, Z., Kumar, R., Yang, X., Fidler, I. J. (1997) Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell 88, 801-810.
30. Dong, Z., Yoneda, J., Kumar, R., Fidler, I. J. (1998) Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce GM-CSF. J. Exp. Med. 188, 755-763.
31. Fidler, I. J. (1975) Activation in vitro of mouse macrophages by syngeneic, allogeneic lymphocyte supernatants. J. Natl. Cancer Inst. 55, 1159-1163.
32. Hughes, D. A., Fraser, I. P., Gordon, S. (1994) Murine M phi scavenger receptor: adhesion function and expression. Immunol. Lett. 43, 7-14.
33. Saiki, I., Fidler, I. J. (1985) Synergistic activation of recombinant mouse interferon-γ and muramyl dipeptide of tumoricidal properties in mouse macrophages. J. Immunol. 135, 684-688.
34. Kumar, R., Dong, Z., Fidler, I. J. (1996) Differential regulation of metalloelastase activity in murine peritoneal macrophages by granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor. J. Immunol. 157, 5104-5111.
35. Hanna, N., Fidler, I. J. (1980) The role of natural cytotoxic cells in the destruction of circulating tumor emboli. J. Natl. Cancer Inst. 65, 801-809.
36. Nathan, C. F. (1987) Secretory products of macrophages. J. Clin. Invest. 79, 319-326.
37. Hibbs, J. B., Jr., Traintor, R. R., Vavrin, Z. (1987) Macrophage cytotoxicity: role for L-arginine deaminase and imino nitrogen oxidation to nitrite. Science 235, 473-176.
38. Nathan, C. F. (1982) Secretion of oxygen intermediates: role in effector functions of activated macrophages. Federation Proc. 41, 2206-2211.
39. Carswell, E. A., Old, L. J., Kassell, L. J. (1975) An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 72, 3666-3670.
40. Stuehr, D. J., Grififth, O. W. (1992) Mammalian nitric oxide synthases. Adv. Enzymol. Rel. Areas Mol. Biol. 65, 287-346.
41. Blake, D. R., Allen, R. E., Lunec, J. (1987) Free radicals in biological systems: a review oriented to inflammatory processes. Br. Med. Bull. 43, 371-385.
42. Cheeseman, K. H., Slater, T. F. (1993) An introduction to free radical biochemistry. Br. Med. Bull. 49, 481-493.
43. Spirito, S., Dougherty, J., O'Byrne, E., Ganu, V., Goldberg, R. L. (1995) Metalloprotease inhibitors halt collagen breakdown in IL-1-induced bovine nasal cartilage cultures. Inflamm. Res. 44, 5131-5132.
44. Charak, B. S., Agah, R., Mazumdar, A. (1993) GM-CSF induces ADCC in bone marrow macrophages: application in bone marrow transplantation. Blood 81, 3474-3479.
45. Bendall, L. J., Kortlepel, K., Gottlieb, D. J. (1995) GM-CSF enhances IL-2-activated natural killer cell lysis of clonogenic AML cells by upregulating target cell expression of ICAM-1. Leukemia 9, 677-684.
46. Chachoua, A., Oratz, R., Liebes, L., Alter, R. S., Felice, A., Peace, D., Vilcek, J., Blum, R. H. (1994) Phase Ib trial of granulocyte-macrophage colony-stimulating factor combined with monoclonal antibody R24 in patients with metastatic melanoma. J. Immunother. 16, 132-141.
47. Ragnhammar, P., Fagerberg, J., Frodin, J.-E., Hjelm, A.-L., Lindelmalm, C., Magnusson, I., Masucci, G., Mellstedt, H. (1985) Effect of monoclonal antibody 17-1A and GM-CSF in patients with advanced colorectal carcinoma-long lasting, complete remissions can be induced. Int. J. Cancer 53, 751-758.