Induction of antitumor effect on human esophageal carcinoma cells by the retroviral expression of granulocyte macrophage-colony stimulating factor gene

International Journal of Oncology

Volumn 12, Issue 2, 1998, Pages 321-324

  Sugaya, Makoto ^a   Tagawa, Masatoshi ^b   Matsubara, Hisahiro ^a   Gunji, Yoshio ^a   Takenaga, Keizo ^b   Maeda, Tomoko ^a   Koide, Yoshio ^a   Asano, Takehide ^a   Ochiai, Takenori ^a   Isono, Kaichi ^a   Sakiyama, Shigeru ^b  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA CANCER CENTER   (Japan)

Author keywords

Antitumor effect; Esophageal cancer; Gene therapy; Granulocyte macrophage colony stimulating factor

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELLULAR IMMUNODEFICIENCY; CONTROLLED STUDY; ESOPHAGUS CARCINOMA; FEMALE; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RETROVIRUS; TUMOR GROWTH;

EID: 13144276269     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.12.2.321     Document Type: Article

References (22)

1. Hurt R: Surgical treatment of carcinoma of the esophagus. Thorax 46: 526-535, 1991.
2. Kato H: Diasnosis and treatment of esophageal neoplasms. Jpn J Cancer Res 86: 993-1009, 1995.
3. Mooltcn FL and Wells JM: Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst 82: 297-300, 1990.
4. Ram Z, Culver KW, Walbridge S, Blaese RM and Oldfield EH: In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats. Cancer Res 53: 83-88, 1993.
5. Vile RG, Nelson JA, Castleden S, Chong H and Hart IR: Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component. Cancer Res 54: 6228-6234, 1994.
6. Tepper RI and Mulé JJ: Experimental and clinical studies of cytokine gene-modified tumor cells. Hum Gene Ther 5: 153-164, 1994.
7. McBride WH, Economou JS, Syljuasen RG, Parrish C, Hackman D, Latham V, Chiang CS and Dougherty GJ: The effects of cytokine gene transfer into tumors on host cell infiltration and regression. Anticancer Res 16: 1139-1144, 1996.
8. Roth JA and Cristiano RJ: Gene therapy for cancer: what have we done and where are we going? J Natl Cancer Inst 88: 21-39, 1997.
9. Inaba K, Inaba M, Romani N, Aya H, Deguchi M, Ikehara S, Muramatsu S and Steinman RM: Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony stimulating factor. J Exp Med 176: 1693-1970, 1992.
10. Sanda MG, Ayyagari SR, Jaffee EM, Epstein JI, Clift SL, Cohen KL, Dranoff G, Pardoll DM, Mulligan RC and Simons JW: Demonstration of a rational strategy for human prostate cancer gene therapy. J Urol 151: 622-628, 1994.
11. Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levisky H, Brose K, Jackson V, Hamada H, Pardoll D and Mulligan RC: Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 90: 3539-3543, 1993.
12. Saito S, Bannerji R, Gansbacher B, Rosenthal FM, Romanenko P, Heston WDW, Fair WR and Gilboa E: Immunotherapy of bladder cancer with cytokine gene-modified tumor vaccines. Cancer Res 54: 3516-3520, 1994.
13. Miller AD and Rosman GJ: Improved retroviral vectors for gene transfer and expression. Biotechniques 7: 980-990, 1989.
14. Miyatake S, Otsuka T, Yokota T, Lee F and Arai K: Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes. EMBO J 4: 2561-2568, 1985.
15. Lee F, Yokota T, Otsuka T, Gemmell L, Larson N, Luh J, Arai K and Rennick D: Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells. Proc Natl Acad Sci USA 82: 4360-4364, 1985.
16. Gunji Y, Tagawa M, Matsubara H, Takenaga K, Shimada H, Kondo F, Suzuki T, Nakajima K, Aoki T, Asano T, Ochiai T, Isono K, Kageyama H, Nakamura Y and Sakiyama S: Murine colon carcinoma cells engineered to produce human interleukin-2 induce tumor-specific anti-tumor response. Int J Cancer 66: 135-139, 1996.
17. Kennedy JD, Pierce CW and Lake JP: Extrathymic T cell maturation. Phenotypic analysis of T cell subsets in nude mice as a function of age. J Immunol 148: 1620-1629, 1992.
18. Li Y, Newby SA, Johnston JV, Hellström KE and Chen L: Protective immunity induced by B7/CD28-costimulated γδ T cells to the EL-4 lymphoma in allogenic athymic mice. J Immunol 155: 5705-5710, 1995.
19. Lee C-T, Wu S, Ciernik F, Chen H, Nadaf-Rahrov S, Gabrilovich D and Carbone DP: Genetic immunotherapy of established tumors with adenovirus-murine granulocyte-macrophage colony-stimulating factor. Hum Gene Ther 8: 187-193, 1997.
20. Yu JS, Burwick JA, Dranoff G and Breakefield XO: Gene therapy for metastatic brain tumors by vaccination with granulocyte-macrophage colony stimulating factor-transduced tumor cells. Hum Gene Ther 8: 1065-1072, 1997.
21. Ellen KAO, O'Rourke MGE, Johnson GR, Parry G, Misko IS, Schmidt CW, Parsons PG, Burrows SR, Cross S, Fell A, Li CL, Bell JR, Dubois PJ, Moss DJ, Good MF, Kelso A, Cohen LK, Dranoff G and Mulligan RC: A case report: Immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy. Cancer Immunol Immunother 44: 10-20, 1997.
22. Simons JW, Jaffee EM, Weber CE, Levitsky HI, Nelson WG, Carducci MA, Lazenby AJ, Cohen KL, Finn CC, Clift SM, Hauda KM, Beck LA, Leiferman KM, Owens AH Jr, Piantadosi S, Dranoff G, Mulligan RC, Pardoll DM and Marshall FF: Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Res 57: 1537-1546, 1997.