Role for IgE in airway secretions: IgE immune complexes are more potent inducers than antigen alone of airway inflammation in a murine model

Journal of Immunology

Volumn 164, Issue 5, 2000, Pages 2667-2673

  Zuberi, Riaz I ^a   Apgar, John R ^b   Chen, Swey Shen ^a   Liu, Fu Tong ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E;

AIRBORNE INFECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ATOPY; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; IMMUNE RESPONSE; INFLAMMATION; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0034162549     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2667     Document Type: Article

References (47)

1. Ownby, D. R. 1993. Clinical significance of IgE. In Allergy, Principles and Practice. Mosby-Year Book. St. Louis, p. 1059.
2. Burrows, B., F. D. Martinez, M. Halonen, R. A. Barbee, and M. G. Cline. 1989. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N. Engl. J. Med. 320:271.
3. KleinJan, A., T. Godthelp, A. W. Van Toornenenbergen, and W. J. Fokkens. 1997. Allergen binding to specific IgE in the nasal mucosa of allergic patients. J. Allergy Clin. Immunol. 99:515.
4. Durham, S. R., H. J. Gould, C. P. Thienes, M. R. Jacobson, K. Masuyama, S. Rak, O. Lowhagen, E. Schotman, L. Cameron, and Q. A. Hamid. 1997. Expression of ∈ germ-line gene transcripts and mRNA for the [/oe] heavy chain of IgE in nasal B cells and the effects of topical corticosteroid. Eur. J. Immunol. 27:2899.
5. Crimi, E., A. Scordamaglia, P. Crimi, S. Zupo, and S. Barocci. 1983. Total and specific IgE in serum, bronchial lavage and bronchoalveolar lavage of asthmatic patients. Allergy 38:553.
6. Diaz Sanchez, D., A. R. Dotson, H. Takenaka, and A. Saxon. 1994. Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms. J. Clin. Invest. 94:1417.
7. Peebles, R. S., Jr., M. C. Liu, N. F. Adkinson, Jr., L. M. Lichtenstein, and R. G. Hamilton. 1998. Ragweed-specific antibodies in bronchoalveolar lavage fluids and serum before and after segmental lung challenge: IgE and IgA associated with eosinophil degranulation. J. Allergy Clin. Immunol. 101:265.
8. Renz, H., H. R. Smith, J. E. Henson, B. S. Ray, C. G. Irvin, and E. W. Gelfand. 1992. Aerosolized antigen exposure without adjuvant caused increased IgE production and increased airways responsiveness in the mouse. J. Allergy Clin. Immunol. 89:1127.
9. Kung, T. T., H. Jones, G. K. Adams, S. P. Umland, W. Kreutner, R. W. Egan, R. W. Chapman, and A. S. Watnick. 1994. Characterization of a murine model of allergic pulmonary inflammation. Int. Arch. Allergy Immunol. 105:83.
10. Herz, U., U. Lumpp, J. C. Da Palma, K. Enssle, K. Takatsu, N. Schnoy, A. Daser, E. Kottgen, U. Wahn, and H. Renz. 1996. The relevance of murine animal models to study the development of allergic bronchial asthma. Immunol. Cell Biol. 74: 209.
11. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146:374.
12. Cohn, L., R. J. Homer, A. Marinov, J. Rankin, and K. Bottomly. 1997. Induction of airway mucus production by T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J. Exp. Med. 186:1737.
13. Brusselle, G. G., J. C. Kips, J. H. Tavernier, J. G. Van der Heyden. C. A. Cuvelier, R. A. Pauwels, and H. Bluethmann. 1994. Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin. Exp. Allergy 24:73.
14. Corry, D. B., H. G. Folkesson, M. L. Warnock, D. J. Erle, M. A. Matthay, J. P. Wiener-Kronish, and R. M. Locksley. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 183:109.
15. Hamelmann, E., A. Oshiba, J. Schwarze, K. Bradley, J. Loader, G. L. Larsen, and E. W. Gelfand. 1997. Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. Am. J. Respir. Cell Mol. Biol. 16:674.
16. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperractivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195.
17. DiCosmo, B. F., G. P. Geba, D. Picarella, J. A. Elias, J. A. Rankin, B. R. Stripp, J. A. Whitsett, and R. A. Flavell. 1994. Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity. J. Clin. Invest. 94:2028.
18. Wills-Karp, M., J. Luyimbazi, X. Xu, B. Schofield, T. Y. Neben, C. L. Karp, and D. D. Donaldson. 1998. Interleukin-13: central mediator of allergic asthma. Science 282:2258.
19. Grünig, G., M. Warnock, A. E. Wakil, R. Venkayya, F. Brombacher, D. M. Rennick, D. Sheppard, M. Mohrs, D. D. Donaldson, R. M. Locksley, and D. B. Corry. 1998. Requirement for IL-13 independenlly of IL-4 in experimental asthma. Science 282:2261.
20. Zhu, Z., R. J. Homer, Z. Wang, Q. Chen, G. P. Geba, J. Wang, Y. Zhang, and J. A. Elias. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779.
21. Hessel, E. M., W. W. Cruikshank, I. Van Ark, J. J. De Bie, B. Van Esch, G. Hofman, F. P. Nijkamp, D. M. Center, and A. J. M. Van Oosterhout. 1998. Involvement of IL-16 in the induction of airway hyper-responsiveness and upregulation of IgE in a murine model of allergic asthma. J. Immunol. 160:2998.
22. Gavett, S. H., D. J. O'Hearn, X. M. Li, S. K. Huang, F. D. Finkelman, and M. Wills-Karp. 1995. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J. Exp. Med. 182:1527.
23. Kips, J. C., G. J. Brusselle, G. F. Joos, R. A. Peleman, J. H. Tavernier, R. R. Devos, and R. A. Pauweis. 1996. Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice. Am. J. Respir. Crit. Care Med. 153:535.
24. Fung-Leung, W. P., J. D. Sousa-Hitzler, A. Ishaque, L. B. Zhou, J. Pang, K. Ngo, J. A. Panakos, E. Chourmouzis, F. T. Liu, and C. Y. Lau. 1996. Transgenic mice expressing the human high-affinity immunogiobulin (Ig) E receptor α chain respond to human IgE in mast cell degranulation and in allergic reactions. J. Exp. Med. 183:49.
25. Liu, F.-T., J. W. Bohn, E. L. Ferry, H. Yamamoto, C. A. Molinaro, L. A. Sherman, N. R. Klinman, and D. H. Katz. 1980. Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation and characterization. J. Immunol. 124:2728.
26. Liu, F.-T., and D. H. Katz. 1984. Mouse monoclonal IgE antibodies specific for ragweed pollen antigens. Hybridoma 3:277.
27. Chen, S.-S., and J. Cerny. 1980. Studies on hapten-specific B cell tolerance in vitro. I. The inductive phase of central B cell tolerance. J. Immunol. 125:1962.
28. Chvatchko, Y., M. H. Kosco Vilbois, S. Herren, J. Lefort, and J. Y. Bonnefoy. 1996. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J Exp. Med. 184:2353.
29. Kehry, M. R., and L. C. Yamashita. 1989. Low-affinity IgE receptor (CD23) function on mouse B cells: role in IgE-dependent antigen focusing. Proc. Natl. Acad. Sci. USA 86:7556.
30. Pirron, U., T. Schlunck, J. C. Prinz, and E. P. Reiber. 1990. IgE-dependent antigen focusing by human B lymphocytes is mediated by low-affinity receptor for IgE. Eur. J. Immunol. 20:1547.
31. Mudde, G. C., T. T. Hansel, F. C. v.Reijsen, B. F. Osterhoff, and C. A. F. M. Bruijnzeel-Koomen. 1990. IgE: an immunoglobulin specialized in antigen capture? Immunol. Today 11:440.
32. Gosset, P., I. Tillie-Leblond, S. Oudin, O. Parmentier, B. Wallaert, M. Joseph, and A. B. Tonnel. 1999. Production of chemokines and proinflammatory and antiinflammatory cytokines by human alveolar macrophages activated by IgE receptors. J. Allergy Clin. Immunol. 103:289.
33. Yamaguchi, M., C. S. Lantz, H. C. Oettgen, I. M. Katona, T. Fleming, I. Miyajima, J. P. Kinet, and S. J. Galli. 1997. IgE enhances mouse mast cell Fc∈RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions. J. Exp. Med. 185:663.
34. Gauchat, J.-F., S. Henchoz, G. Mazzel, J.-P. Aubry, T. Brunner, H. Blasey, P. Life, D. Talabot, L. Flores-Romo, J. Thompson, et al. 1993. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature 365:340.
35. Maurer, D., E. Fiebiger, B. Reininger, B. Wolff-Winiski, M.-H. Jouvin, O. Kilgus, J.-P. Kinet, and G. Stingl. 1994. Expression of functional high affinity immunoglobulin E receptors (Fc∈RI) on monocytes of atopic individuals. J. Exp. Med. 179:745.
36. Maurer, D., E. Fiebiger, C. Ebner, B. Reininger, G. F. Fischer, S. Wichlas, M. H. Jouvin, M. Schmitt-Egenolf, D. Kraft, J. P. Kinet, and G. Stingl. 1996. Peripheral blood dendritic cells express Fc∈RI as a complex composed of Fc∈RIα- and Fc∈RIγ-chains and can use this receptor for IgE-mediated allergen presentation. J. Immunol. 157:607.
37. Ochiai, K., M. Kagami, K. Umemiya, R. Matsumura, T. Kawashima, and H. Tomioka. 1996. Expression of high-affinity IgE receptor (Fc[/oe]RI) on human alveolar macrophages from atopic and non-atopic patients. Int. Arch. Allergy Immunol. 111(Suppl. 1):55.
38. Huang, C., D. S. Friend, W. T. Qiu, G. W. Wong, G. Morales, J. Hunt, and R. L. Stevens. 1998. Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6. J. Immunol. 160:1910.
39. Teran, L. M., M. G. Campos, B. T. Begishvilli, J.-M. Shroder, R. Djukanovic, J. K. Shute, M. K. Church, S. T. Holgate, and D. E. Davies. 1997. Identification of neutrophil chemotactic factors in bronchoalveolar lavage fluid of asthmatic patients. Clin. Exp. Allergy 27:196.
40. Wenzel, S. E., S. J. Szefler, D. Y. M. Leung, S. I. Sloan, M. D. Rex, and R. J. Martin. 1997. Bronchoscopic evaluation of severe asthma. Am. J. Respir. Crit. Care Med. 156:737.
41. Garlisi, C. G., A. Falcone, J. A. Hey, T. M. Paster, X. Fernandez, C. A. Rizzo, M. Minnicozzi, H. Jones, M. M. Billah, R. W. Egan, and S. P. Umland. 1997. Airway eosinophils, T cells, Th2-type cytokine mRNA, and hyperreactivity in response to aerosol challenge of allergic mice with previously established pulmonary inflammation. Am. J. Respir. Cell Mol. Biol. 17:642.
42. Coyle, A. J., K. Wagner, C. Bertrand, S. Tsuyuki, J. Bews, and C. Heusser. 1996. Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: Inhibition by a non-anaphylactogenic anti-IgE antibody. J. Exp. Med. 183:1303.
43. Mehlhop, P. D., M. Van de Rijn, A. B. Goldberg, J. P. Brewer, V. P. Kurup, T. R. Martin, and H. C. Oettgen. 1997. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc. Natl. Acad. Sci. USA 94:1344.
44. Galli, S. J., and J. J. Costa. 1995. Mast-cell-leukocyte cylokine cascades in allergic inflammation. Allergy 50:851.
45. Takeda, K., E. Hamelmann, A. Joetham, L. D. Shultz, G. L. Larsen, C. G. Irvin, and E. W. Gelfand. 1997. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J. Exp. Med. 186:449.
46. Kung, T. T., D. Stelts, J. A. Zurcher, H. Jones, S. P. Umland, W. Kreutner, R. W. Egan, and R. W. Chapman. 1995. Mast cells modulate allergic pulmonary eosinophilia in mice. Am. J. Respir. Cell Mol. Biol. 12:404.
47. Galli, S. J. 1997. Complexity and redundancy in the pathogenesis of asthma: reassessing the roles of mast cells and T cells. J. Exp. Med. 186:343.