Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor α chain respond to human IgE in mast cell degranulation and in allergic reactions

Journal of Experimental Medicine

Volumn 183, Issue 1, 1996, Pages 49-56

  Fung Leung, Wai Ping ^a,b   De Sousa Hitzler, Jean ^b   Ishaque, Armana ^b   Zhou, Lubing ^a,b   Pang, Jesse ^a,b   Ngo, Karen ^a,b   Panakos, Julie A ^b   Chourmouzis, Erika ^b   Liu, Fu Tong ^c   Lau, Catherine Y ^b  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b R W Johnson Pharmaceutical Res I   (Canada)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN RECEPTOR;

ALLERGY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; TRANSGENIC MOUSE;

ANAPHYLAXIS; ANIMALS; BASE SEQUENCE; CELL DEGRANULATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN E; MAST CELLS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PASSIVE CUTANEOUS ANAPHYLAXIS; PROTEIN CONFORMATION; RECEPTORS, IGE; SIGNAL TRANSDUCTION; SKIN; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC;

EID: 13344284650     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.1.49     Document Type: Article

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