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Volumn 2, Issue 2, 2000, Pages 117-127

Overexpression of Mad transcription factor inhibits proliferation of cultured human hepatocellular carcinoma cells along with tumor formation in immunodeficient animals

Author keywords

Adenovirus; c Myc; Gene therapy; Hepatocellular carcinoma; Mad

Indexed keywords

ADENOVIRIDAE; ANIMALIA;

EID: 0034154747     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-2254(200003/04)2:2<117::aid-jgm96>3.0.co;2-x     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 0003461672 scopus 로고
    • Viral mechanisms in hepatic oncogenesis
    • Arias IM, Boyer J, Fausto N, Jacoby WR, Schachter D, Shafritz DA (eds). Raven Press Limited: New York
    • Gupta S, Shafritz DA. Viral mechanisms in hepatic oncogenesis. In The Liver: Biology and Pathobiology (3rd edn). Arias IM, Boyer J, Fausto N, Jacoby WR, Schachter D, Shafritz DA (eds). Raven Press Limited: New York, 1994; 1429-1453.
    • (1994) The Liver: Biology and Pathobiology (3rd Edn) , pp. 1429-1453
    • Gupta, S.1    Shafritz, D.A.2
  • 3
    • 0031032773 scopus 로고    scopus 로고
    • A minimal regulatory region maintains constitutive expression of the max gene
    • Peters MA, Sollenberger KG, Kao TL, Taparowsky EJ. A minimal regulatory region maintains constitutive expression of the max gene. Mol Cell Biol 1997; 17: 1037-1048.
    • (1997) Mol Cell Biol , vol.17 , pp. 1037-1048
    • Peters, M.A.1    Sollenberger, K.G.2    Kao, T.L.3    Taparowsky, E.J.4
  • 4
    • 0032554768 scopus 로고    scopus 로고
    • Lack of transcriptional repression by max homodimers
    • Yin X, Grove L, Prochownik EV. Lack of transcriptional repression by max homodimers. Oncogene 1998; 16: 2629-2637.
    • (1998) Oncogene , vol.16 , pp. 2629-2637
    • Yin, X.1    Grove, L.2    Prochownik, E.V.3
  • 5
    • 0027425699 scopus 로고
    • Direct role for Myc in transcription initiation mediated by interactions with TFII-I
    • Roy AL, Carruthers C, Gutjahr T, Roeder RG. Direct role for Myc in transcription initiation mediated by interactions with TFII-I. Nature 1993; 365: 359-361.
    • (1993) Nature , vol.365 , pp. 359-361
    • Roy, A.L.1    Carruthers, C.2    Gutjahr, T.3    Roeder, R.G.4
  • 6
    • 0028169192 scopus 로고
    • c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II
    • Li LH, Nerlov C, Prendergast G, MacGregor D, Ziff EB. c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J 1994; 13: 4070-4079.
    • (1994) EMBO J , vol.13 , pp. 4070-4079
    • Li, L.H.1    Nerlov, C.2    Prendergast, G.3    MacGregor, D.4    Ziff, E.B.5
  • 7
    • 0033613854 scopus 로고    scopus 로고
    • Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC
    • Wu KJ, Polack A, Dalla-Favera R. Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC. Science 1999; 283: 676-679.
    • (1999) Science , vol.283 , pp. 676-679
    • Wu, K.J.1    Polack, A.2    Dalla-Favera, R.3
  • 8
    • 0027408096 scopus 로고
    • Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
    • Ayer DE, Kretzner L, Eisenman RN. Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell 1993; 72: 211-222.
    • (1993) Cell , vol.72 , pp. 211-222
    • Ayer, D.E.1    Kretzner, L.2    Eisenman, R.N.3
  • 10
    • 0029129054 scopus 로고
    • Differential effects by Mad and Max on transformation by cellular and viral oncoproteins
    • Cerni C, Bousset K, Seelos C, Burkhardt H, Henriksson M, Luscher B. Differential effects by Mad and Max on transformation by cellular and viral oncoproteins. Oncogene 1995; 11: 587-596.
    • (1995) Oncogene , vol.11 , pp. 587-596
    • Cerni, C.1    Bousset, K.2    Seelos, C.3    Burkhardt, H.4    Henriksson, M.5    Luscher, B.6
  • 11
    • 0029588594 scopus 로고
    • Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis
    • Hurlin PJ, Foley KP, Ayer DE, Eisenman RN, Hanahan D, Arbeit JM. Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis. Oncogene 1995; 11: 2487-2501.
    • (1995) Oncogene , vol.11 , pp. 2487-2501
    • Hurlin, P.J.1    Foley, K.P.2    Ayer, D.E.3    Eisenman, R.N.4    Hanahan, D.5    Arbeit, J.M.6
  • 12
    • 0028940364 scopus 로고
    • An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3
    • Schreiber-Agus N, Chin L, Chen K, Torres R, Rao G, Guida P, Skoultchi AI, DePinho RA. An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3. Cell 1995; 80: 777-786.
    • (1995) Cell , vol.80 , pp. 777-786
    • Schreiber-Agus, N.1    Chin, L.2    Chen, K.3    Torres, R.4    Rao, G.5    Guida, P.6    Skoultchi, A.I.7    DePinho, R.A.8
  • 13
    • 0029737603 scopus 로고    scopus 로고
    • Sin3 corepressor function in Myc-induced transcription and transformation
    • Harper SE, Qiu Y, Sharp PA. Sin3 corepressor function in Myc-induced transcription and transformation. Proc Natl Acad Sci USA 1996; 93: 8536-8540.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8536-8540
    • Harper, S.E.1    Qiu, Y.2    Sharp, P.A.3
  • 15
    • 0031172243 scopus 로고    scopus 로고
    • Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity
    • Sommer A, Hilfenhaus S, Menkel A, Kremmer E, Seiser C, Loidl P, Luscher B. Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity. Curr Biol 1997; 7: 357-365.
    • (1997) Curr Biol , vol.7 , pp. 357-365
    • Sommer, A.1    Hilfenhaus, S.2    Menkel, A.3    Kremmer, E.4    Seiser, C.5    Loidl, P.6    Luscher, B.7
  • 16
    • 0028889811 scopus 로고
    • Mad3 and Mad4: Novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
    • Hurlin PJ, Queva C, Koskinen PJ, Steingrimsson E, Ayer DE, Copeland NG, Jenkins NA, Eisenman RN. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J 1995; 14: 5646-5659.
    • (1995) EMBO J , vol.14 , pp. 5646-5659
    • Hurlin, P.J.1    Queva, C.2    Koskinen, P.J.3    Steingrimsson, E.4    Ayer, D.E.5    Copeland, N.G.6    Jenkins, N.A.7    Eisenman, R.N.8
  • 18
    • 0030906519 scopus 로고    scopus 로고
    • Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation
    • Cultraro CM, Bino T, Segal S. Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation. Mol Cell Biol 1997; 17: 2353-2359.
    • (1997) Mol Cell Biol , vol.17 , pp. 2353-2359
    • Cultraro, C.M.1    Bino, T.2    Segal, S.3
  • 19
    • 0030864848 scopus 로고    scopus 로고
    • Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced differentiation of U-937 monoblasts and F9 teratocarcinoma cells
    • Larsson LG, Bahram F, Burkhardt H, Luscher B. Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced differentiation of U-937 monoblasts and F9 teratocarcinoma cells. Oncogene 1997; 15: 737-748.
    • (1997) Oncogene , vol.15 , pp. 737-748
    • Larsson, L.G.1    Bahram, F.2    Burkhardt, H.3    Luscher, B.4
  • 21
    • 0032567946 scopus 로고    scopus 로고
    • Sequential expression of the MAD family of transcriptional repressors during differentiation and development
    • Queva C, Hurlin PJ, Foley KP, Eisenman RN. Sequential expression of the MAD family of transcriptional repressors during differentiation and development. Oncogene 1998; 16: 967-977.
    • (1998) Oncogene , vol.16 , pp. 967-977
    • Queva, C.1    Hurlin, P.J.2    Foley, K.P.3    Eisenman, R.N.4
  • 22
    • 0032472914 scopus 로고    scopus 로고
    • Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation
    • Foley KP, McArthur GA, Queva C, Hurlin PJ, Soriano P, Eisenman RN. Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. EMBO J 1998; 17: 774-785.
    • (1998) EMBO J , vol.17 , pp. 774-785
    • Foley, K.P.1    McArthur, G.A.2    Queva, C.3    Hurlin, P.J.4    Soriano, P.5    Eisenman, R.N.6
  • 25
    • 0029053565 scopus 로고
    • Inducible expression of Mad accelerates growth arrest of serum deprived human glioblastoma cells
    • Roy B, Reisman D. Inducible expression of Mad accelerates growth arrest of serum deprived human glioblastoma cells. Cell Biol Int 1995; 19: 307-313.
    • (1995) Cell Biol Int , vol.19 , pp. 307-313
    • Roy, B.1    Reisman, D.2
  • 26
    • 0029077733 scopus 로고
    • Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells
    • Chen J, Willingham T, Margraf LR, Schreiber-Agus N, DePinho RA, Nisen PD. Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells. Nat Med 1995; 1: 638-643.
    • (1995) Nat Med , vol.1 , pp. 638-643
    • Chen, J.1    Willingham, T.2    Margraf, L.R.3    Schreiber-Agus, N.4    DePinho, R.A.5    Nisen, P.D.6
  • 28
    • 0032980593 scopus 로고    scopus 로고
    • Rapid clearance of syngeneic transplanted hepatocytes following transduction with E-1-deleted adenovirus indicates early host immune responses and offers novel ways for studying viral vector, target cell and host interactions
    • Gagandeep S, Ott M, Sokhi R, Gupta S. Rapid clearance of syngeneic transplanted hepatocytes following transduction with E-1-deleted adenovirus indicates early host immune responses and offers novel ways for studying viral vector, target cell and host interactions. Gene Ther 1999; 6: 729-736.
    • (1999) Gene Ther , vol.6 , pp. 729-736
    • Gagandeep, S.1    Ott, M.2    Sokhi, R.3    Gupta, S.4
  • 29
    • 0032496152 scopus 로고    scopus 로고
    • Simultaneous upregulation of viral receptor expression and DNA synthesis is required for increasing efficiency of retroviral hepatic gene transfer
    • Ott M, Stockert RJ, Ma Q, Gagandeep S, Gupta S. Simultaneous upregulation of viral receptor expression and DNA synthesis is required for increasing efficiency of retroviral hepatic gene transfer. J Biol Chem 1998; 273: 11954-11961.
    • (1998) J Biol Chem , vol.273 , pp. 11954-11961
    • Ott, M.1    Stockert, R.J.2    Ma, Q.3    Gagandeep, S.4    Gupta, S.5
  • 30
    • 0032996680 scopus 로고    scopus 로고
    • Paclitaxel shows cytotoxic activity in human hepatocellular carcinoma cell lines
    • Gagandeep S, Novikoff PM, Ott M, Gupta S. Paclitaxel shows cytotoxic activity in human hepatocellular carcinoma cell lines. Cancer Lett 1999; 136: 109-118.
    • (1999) Cancer Lett , vol.136 , pp. 109-118
    • Gagandeep, S.1    Novikoff, P.M.2    Ott, M.3    Gupta, S.4
  • 31
    • 0026516233 scopus 로고
    • Mitogenic effects of hepatic stimulator substance on cultured nonparenchymal liver epithelial cells
    • Gupta S, LaBrecque DR, Shafritz DA. Mitogenic effects of hepatic stimulator substance on cultured nonparenchymal liver epithelial cells. Hepatology 1992; 15: 485-491.
    • (1992) Hepatology , vol.15 , pp. 485-491
    • Gupta, S.1    LaBrecque, D.R.2    Shafritz, D.A.3
  • 32
    • 0032945255 scopus 로고    scopus 로고
    • Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver
    • Ott M, Rajvanshi P, Sokhi R, Alpini G, Aragona E, Dabeva M, Shafritz DA, Gupta S. Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver. J Pathol 1999; 187: 365-373.
    • (1999) J Pathol , vol.187 , pp. 365-373
    • Ott, M.1    Rajvanshi, P.2    Sokhi, R.3    Alpini, G.4    Aragona, E.5    Dabeva, M.6    Shafritz, D.A.7    Gupta, S.8
  • 33
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • Knowles BB, Howe CC, Aden DP. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 1980; 209: 497-499.
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 34
    • 0019966544 scopus 로고
    • Growth of human hepatoma cells lines with differentiated functions in chemically defined medium
    • Nakabayashi H, Taketa K, Miyano M, Yamane T, Sato J. Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res 1982; 42: 3858-3863.
    • (1982) Cancer Res , vol.42 , pp. 3858-3863
    • Nakabayashi, H.1    Taketa, K.2    Miyano, M.3    Yamane, T.4    Sato, J.5
  • 35
    • 0023037274 scopus 로고
    • Comparative expression of hepatitis B virus antigens in several cell model systems
    • Aspinall S, Alexander J, Bos P. Comparative expression of hepatitis B virus antigens in several cell model systems. J Gen Virol 1986; 67: 2315-2323.
    • (1986) J Gen Virol , vol.67 , pp. 2315-2323
    • Aspinall, S.1    Alexander, J.2    Bos, P.3
  • 36
    • 85193290528 scopus 로고
    • C-myc and c-Ha-ras expression and c-Ha-ras polymorphisms in primary hepatocellular carcinoma occur independently of hepatitis B viral DNA integration
    • Gupta S, Parimoo S, Valinluck B, Govindarajan S. C-myc and c-Ha-ras expression and c-Ha-ras polymorphisms in primary hepatocellular carcinoma occur independently of hepatitis B viral DNA integration. Hepatogastroenterology 1992; 39: 188-194. Eur Clin Digest Dis Suppl - Series 1: 184-190.
    • (1992) Hepatogastroenterology , vol.39 , pp. 188-194
    • Gupta, S.1    Parimoo, S.2    Valinluck, B.3    Govindarajan, S.4
  • 37
    • 85193302875 scopus 로고    scopus 로고
    • Series
    • Gupta S, Parimoo S, Valinluck B, Govindarajan S. C-myc and c-Ha-ras expression and c-Ha-ras polymorphisms in primary hepatocellular carcinoma occur independently of hepatitis B viral DNA integration. Hepatogastroenterology 1992; 39: 188-194. Eur Clin Digest Dis Suppl - Series 1: 184-190.
    • Eur Clin Digest Dis Suppl , vol.1 , pp. 184-190
  • 38
    • 0032945255 scopus 로고    scopus 로고
    • Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver
    • Ott M, Rajvanshi P, Sokhi R, Alpini G, Aragona E, Dabeva M, Shafritz DA, Gupta S. Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver. J Pathol 1999; 187: 365-373.
    • (1999) J Pathol , vol.187 , pp. 365-373
    • Ott, M.1    Rajvanshi, P.2    Sokhi, R.3    Alpini, G.4    Aragona, E.5    Dabeva, M.6    Shafritz, D.A.7    Gupta, S.8
  • 39
    • 0026749324 scopus 로고
    • IL-2 and EGF receptors stimulate the hemopoeitic cell cycle via different signalling pathways: Demonstration of a novel role for c-myc
    • Shibuya H, Yoneyama M, Ninomiya-Tsuji J, Matsumoto K, Taniguchi T. IL-2 and EGF receptors stimulate the hemopoeitic cell cycle via different signalling pathways: demonstration of a novel role for c-myc. Cell 1992; 70: 57-67.
    • (1992) Cell , vol.70 , pp. 57-67
    • Shibuya, H.1    Yoneyama, M.2    Ninomiya-Tsuji, J.3    Matsumoto, K.4    Taniguchi, T.5
  • 40
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • Waldman T, Lengauer C, Kinzler KW, Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 1996; 381: 713-716.
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 42
    • 0032953728 scopus 로고    scopus 로고
    • Hepatocyte transplantation: Emerging insights into mechanisms of liver repopulation and their relevance to potential therapies
    • Gupta S, Gorla GR, Irani AN. Hepatocyte transplantation: emerging insights into mechanisms of liver repopulation and their relevance to potential therapies. J Hepatol 1999; 30: 162-171.
    • (1999) J Hepatol , vol.30 , pp. 162-171
    • Gupta, S.1    Gorla, G.R.2    Irani, A.N.3
  • 43
    • 0031027008 scopus 로고    scopus 로고
    • Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression of Myc binding sites
    • Hurlin PJ, Queva C, Eisenman RN. Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression of Myc binding sites. Genes Dev 1997; 11: 44-58.
    • (1997) Genes Dev , vol.11 , pp. 44-58
    • Hurlin, P.J.1    Queva, C.2    Eisenman, R.N.3
  • 45
    • 0029907285 scopus 로고    scopus 로고
    • Restriction of tumoricidal gene therapy to selected hepatocellular carcinoma cells
    • Gagandeep S, Gupta S. Restriction of tumoricidal gene therapy to selected hepatocellular carcinoma cells. Hepatology 1996; 24: 1317-1319.
    • (1996) Hepatology , vol.24 , pp. 1317-1319
    • Gagandeep, S.1    Gupta, S.2


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