Expression of Mad, an antagonist of Myc oncoprotein function, in differentiating keratinocytes during tumorigenesis of the skin

British Journal of Cancer

Volumn 73, Issue 11, 1996, Pages 1347-1355

  Lymboussaki, A ^a   Kaipainen, A ^a   Hatva, E ^a   Vastrik I ^a   Jeskanen, L ^a   Jalkanen, M ^b   Werner, S ^c   Stenback F ^d   Alitalo, R ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d UNIVERSITY OF OULU   (Finland)

Author keywords

Carcinogenesis; Differentiation; Mad; Myc oncoprotein

Indexed keywords

ONCOPROTEIN; RIBONUCLEASE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL CARCINOMA; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIUM TUMOR; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; KERATINOCYTE; MOUSE; NONHUMAN; ONCOGENE MYC; PRIORITY JOURNAL; SKIN CARCINOGENESIS; SQUAMOUS CELL CARCINOMA; WOUND HEALING;

EID: 0029934983     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.257     Document Type: Article

References (32)

1. ALITALO K, MÄKELÄ TP, SAKSELA K, KOSKINEN P AND HIRVONEN H. (1992). Oncogene amplification: analysis of myc oncoproteins. In Gene Amplification in Mammalian Cells: Techniques and Applications, R Kellems (ed.), pp. 371-382. Marcel Dekker: New York.
2. AMATI B, LITTLEWOOD TD, EVAN GI AND LAND H. (1993). The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. EMBO J., 12, 5083-5087.
3. AYER DE AND EISENMAN RN. (1993). A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocytemacrophage differentiation. Genes Dev., 7, 2110-2119.
4. AYER DE, KRETZNER L AND EISENMAN RN. (1993). Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell, 72, 1-20.
5. AYER DE, LAWRENCE QA AND EISENMAN RN. (1995). Mad Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell, 80, 1-20.
6. BJELOGRLIC NM, MÄKINEN M, STENBÄCK F AND VÄHÄKANGAS K. (1994). Benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts and increased p53 protein in mouse skin. Carcinogenesis, 15, 771-774.
7. BLACKWOOD EM AND EISENMAN RN. (1991). Max: a helix loop helix zipper protein that forms a sequence-specific DNA-binding complex with myc. Science, 251, 1211-1217.
8. BREMNER R, KEMP CJ AND BALMAIN A. (1994). Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors. Mol. Carcinog., 11, 90-97.
9. CANTLLY LC, CARPENETER C, DUCKWORTH B, GRAZIANI A, KAPELLER R AND SOLTOFF S. (1991). Oncogenes and signal transduction. Cell, 64, 281-302.
10. CHOMCZYNSKI P AND SACCHI N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. Anal. Biochem., 162, 156-159.
11. ELENIUS K, VAINIO S, LAATO M, SALMIVIRTA M, THESLEFF I AND JALKANEN M. (1991). Induced expression of syndecan in healing wounds. J. Cell Biol., 114, 585-595.
12. FUCHS E. (1990). Epidermal differentiation: the bare essentials. J. Cell Biol., 111, 2807-2814.
13. FUCHS E. (1993). Epidermal differentiation and keratin gene expression. J. Cell Sci. Suppl., 17, 197-208.
14. HINKES MT, GOLDBERGER OA, NEUMANN PE, KOKENYESI R AND BERNFIELD M. (1993). Organization and promoter activity of the mouse syndecan-1 gene. J. Biol. Chem., 268, 11440-11448.
15. HURLIN PJ, QUEVA C, KOSKINEN PJ, STEINGRIMSSON E, AYER DE, COPELAND NG, JENKINS NA AND EISENMAN RN. (1995). Mad3 and Mad4: novel Max-interacting transcriptional repressers that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J., 14, 5646-5659.
16. INKI P, JOENSU H, GRENMAN R, KLEMI P AND JALKANEN M. (1994). Association between syndecan-1 expression and clinical outcome in squamous cell carcinoma of the head and neck. Br. J. Cancer, 70, 319-323.
17. JALKANEN M, NGUYEN H, RAPRAEGER A, KURN N AND BERNFIELD M. (1985). Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody. J. Cell Biol., 101, 976-984.
18. KORHONEN M AND STENBACK F. (1984). Adenocarcinoma metastatic to the uterine cervix. Gynecol. Obstet. Invest., 17, 57-65.
19. LARSSON L, PETTERSSON M, ÖBERG F, NILSSON K AND LÜSCHER B. (1994). Expression of mad, mxil, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc. Oncogene, 9, 1247-1252.
20. LÜSCHER B AND EISENMAN RN. (1990). New light on Myc and Myb. Part I. Myc. Genes Dev., 4, 2025-2035.
21. MALI M, JAAKKOLA P, ARVILOMMI AM AND JALKANEN M. (1990). Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans. J. Biol. Chem., 265, 6884-6889.
22. MORGENBESSER SD AND DEPINHO RA. (1994). Use of transgenic mice to study myc family gene function in normal mammalian development and in cancer. Cancer Biol., 5, 21-36.
23. STENBÄCK F. (1978). Life history and histopathology of ultraviolet light-induced skin tumors. Natl Cancer Inst. Monogr., 50, 57-70.
24. TOKUNAGA K, TANIGUCHI H, YODA K, SHIMIZU M AND SAKIYAMA S. (1986). Nucleotide sequence of a full-length cDNA for mouse cytoskeletal beta-actin mRNA. Nucleic Acids Res., 14, 2829-2833.
25. VÄSTRIK I, KOSKINEN PJ, ALITALO R AND MÄKELÄ TP. (1993). Alternative mRNA forms and open reading frames of the max gene. Oncogene, 8, 503-507.
26. VÄSTRIK I, KAIPAINKN A, PENTTILÄ TL, LYMBOUSSAKI A, ALITALO R, PARVINEN M AND ALITALO K. (1995). Expression of the Mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro. J Cell Biol., 128, 1197-1208.
27. WERNER S, PETERS KG, LONGAKER MT, FULLER-PAGE F, BANDA MJ AND WILLIAMS LT. (1992). Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proc. Natl Acad. Sci. USA, 89, 6896-6900.
28. WILKINSON DG, BAILES JA, CHAMPION JE AND MACMAHON AP. (1987a). A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression. Development, 99, 493-500.
29. WILKINSON DG, BAILES JA AND MACMAHON AP. (1987b). Expression of proto-oncogene int-1 is restricted to specific neural cells in the development of mouse embryos. Cell, 50, 79-88.
30. YUSPA SH. (1994). The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis. Thirty-third GHA Clowes memorial award lecture. Cancer Res., 54, 1178-1189.
31. YUSPA SH, KILKENNY A, CHENG C, ROOP D, HENNINGS H, KRUSZEWSKI F AND LEE E. (1991). Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis. Environ. Health Perspect., 93, 3-10.
32. ZERVOS A, GYURIS J AND BRENT R. (1993). Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell, 72, 223-232.