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Volumn 4, Issue 3, 2000, Pages 324-337

Recent applications of polymer-supported reagents and scavengers in combinatorial, parallel, or multistep synthesis

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIAZINE DERIVATIVE; EPIBATIDINE; HYDANTOIN DERIVATIVE; IMIDAZOPYRIDINE DERIVATIVE; ISOCYANIC ACID DERIVATIVE; MATRIX METALLOPROTEINASE INHIBITOR; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; OXAZOLE DERIVATIVE; PERFLUORO COMPOUND; POLYMER; PROPANOLAMINE DERIVATIVE; PYRROLE DERIVATIVE; QUINAZOLINE DERIVATIVE; REAGENT; SCAVENGER; STYRENE DERIVATIVE; THIADIAZOLE DERIVATIVE; UREA DERIVATIVE;

EID: 0034127641     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00096-X     Document Type: Review
Times cited : (237)

References (46)
  • 1
    • 0033035150 scopus 로고    scopus 로고
    • Combinatorial chemistry: The search continues - editorial overview
    • An editorial opinion of how combinatorial thinking has influenced many areas of science
    • Bartlett P.A., Joyce G.F. Combinatorial chemistry: the search continues - editorial overview. Curr Opin Chem Biol. 3:1999;253-255. An editorial opinion of how combinatorial thinking has influenced many areas of science.
    • (1999) Curr Opin Chem Biol , vol.3 , pp. 253-255
    • Bartlett, P.A.1    Joyce, G.F.2
  • 2
    • 85031641125 scopus 로고    scopus 로고
    • Combichem.net homepage on URL
    • Combichem.net homepage on URL: http://www.combichem.net/core.htm.
  • 5
    • 7044263277 scopus 로고    scopus 로고
    • Synthesis and applications of small molecule libraries
    • Thompson L.A., Ellman J.A. Synthesis and applications of small molecule libraries. Chem Rev. 96:1996;555-600.
    • (1996) Chem Rev , vol.96 , pp. 555-600
    • Thompson, L.A.1    Ellman, J.A.2
  • 6
    • 0030607141 scopus 로고    scopus 로고
    • Use of solid supported nuceophiles and electrophiles for the purification of non-peptide small molecule libraries
    • Kaldor S.W., Siegel M.G., Fritz J.E., Dressman B.A., Hahn P.J. Use of solid supported nuceophiles and electrophiles for the purification of non-peptide small molecule libraries. Tetrahedron Lett. 37:1996;7193-7196.
    • (1996) Tetrahedron Lett , vol.37 , pp. 7193-7196
    • Kaldor, S.W.1    Siegel, M.G.2    Fritz, J.E.3    Dressman, B.A.4    Hahn, P.J.5
  • 9
    • 0033152131 scopus 로고    scopus 로고
    • Solution-phase chemical library synthesis using polymer-assisted purification techniques
    • A thorough review of scavenging strategies covering the development of the field through to the end of 1998
    • Parlow J.J., Devraj R.V., South M.S. Solution-phase chemical library synthesis using polymer-assisted purification techniques. Curr Opin Chem Biol. 3:1999;320-336. A thorough review of scavenging strategies covering the development of the field through to the end of 1998.
    • (1999) Curr Opin Chem Biol , vol.3 , pp. 320-336
    • Parlow, J.J.1    Devraj, R.V.2    South, M.S.3
  • 10
    • 0032948663 scopus 로고    scopus 로고
    • Solid-supported reagent strategies for rapid purification of combinatorial synthesis products
    • Booth R.J., Hodges J.C. Solid-supported reagent strategies for rapid purification of combinatorial synthesis products. Acc Chem Res. 32:1999;18-26.
    • (1999) Acc Chem Res , vol.32 , pp. 18-26
    • Booth, R.J.1    Hodges, J.C.2
  • 11
    • 0031817880 scopus 로고    scopus 로고
    • High throughput purification methods in combinatorial solution phase synthesis
    • Ferritto R., Seneci P. High throughput purification methods in combinatorial solution phase synthesis. Drugs Future. 23:1998;643-654.
    • (1998) Drugs Future , vol.23 , pp. 643-654
    • Ferritto, R.1    Seneci, P.2
  • 12
    • 0000757794 scopus 로고    scopus 로고
    • Liquid-phase chemistry: Recent advances in soluble polymer-supported catalysts, reagents and synthesis
    • Wentworth P. Jr., Janda K.D Liquid-phase chemistry: recent advances in soluble polymer-supported catalysts, reagents and synthesis. Chem Commun. 1999;1917-1924.
    • (1999) Chem Commun , pp. 1917-1924
    • Wentworth P., Jr.1    Janda, K.D.2
  • 13
    • 0033570272 scopus 로고    scopus 로고
    • A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD)
    • Boisnard S., Chastanet J., Zhu J. A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD). Tetrahedron Lett. 40:1999;7469-7472.
    • (1999) Tetrahedron Lett , vol.40 , pp. 7469-7472
    • Boisnard, S.1    Chastanet, J.2    Zhu, J.3
  • 14
    • 0033529906 scopus 로고    scopus 로고
    • An easily prepared, air and moisture stable, resin-bound palladium catalyst for Suzuki cross-coupling reactions
    • Zhang T.Y., Allen M.J. An easily prepared, air and moisture stable, resin-bound palladium catalyst for Suzuki cross-coupling reactions. Tetrahedron Lett. 40:1999;5813-5816.
    • (1999) Tetrahedron Lett , vol.40 , pp. 5813-5816
    • Zhang, T.Y.1    Allen, M.J.2
  • 15
    • 0033597375 scopus 로고    scopus 로고
    • A polymer-supported silyl triflate and subsequent functionalization: Synthesis and solid-phase Diels-Alder reactions of silyloxydienes
    • Smith E.M. A polymer-supported silyl triflate and subsequent functionalization: synthesis and solid-phase Diels-Alder reactions of silyloxydienes. Tetrahedron Lett. 40:1999;3285-3288.
    • (1999) Tetrahedron Lett , vol.40 , pp. 3285-3288
    • Smith, E.M.1
  • 16
    • 0033597250 scopus 로고    scopus 로고
    • Ester enolate Claisen rearrangement using a polymer-supported silyl triflate
    • Hu Y., Porco J.A. Jr. Ester enolate Claisen rearrangement using a polymer-supported silyl triflate. Tetrahedron Lett. 40:1999;3289-3292.
    • (1999) Tetrahedron Lett , vol.40 , pp. 3289-3292
    • Hu, Y.1    Porco J.A., Jr.2
  • 17
    • 0033166824 scopus 로고    scopus 로고
    • A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis
    • Kulkarni B.A., Ganesan A. A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis. Tetrahedron Lett. 40:1999;5633-5636.
    • (1999) Tetrahedron Lett , vol.40 , pp. 5633-5636
    • Kulkarni, B.A.1    Ganesan, A.2
  • 19
    • 0033165871 scopus 로고    scopus 로고
    • Solution-phase parallel oxazole synthesis with TosMIC
    • Kulkarni B.A., Ganesan A. Solution-phase parallel oxazole synthesis with TosMIC. Tetrahedron Lett. 40:1999;5637-5638.
    • (1999) Tetrahedron Lett , vol.40 , pp. 5637-5638
    • Kulkarni, B.A.1    Ganesan, A.2
  • 20
    • 0000631409 scopus 로고    scopus 로고
    • Phosgenated p-nitrophenyl(polystyrene)ketoxime or phoxime resin. A new resin for the solid-phase synthesis of ureas via thermolytic cleavage of oxime-carbamates
    • Scialdone M.A., Shuey S.W., Soper P., Hamuro Y., Burns D.M. Phosgenated p-nitrophenyl(polystyrene)ketoxime or phoxime resin. A new resin for the solid-phase synthesis of ureas via thermolytic cleavage of oxime-carbamates. J Org Chem. 63:1998;4802-4807.
    • (1998) J Org Chem , vol.63 , pp. 4802-4807
    • Scialdone, M.A.1    Shuey, S.W.2    Soper, P.3    Hamuro, Y.4    Burns, D.M.5
  • 21
    • 0001089366 scopus 로고    scopus 로고
    • Solid-phase synthesis of acyclic and cyclic amino acid derived urea peptidomimetics using phoxime resin
    • Hamuro Y., Marshall W.J., Scialdone M.A. Solid-phase synthesis of acyclic and cyclic amino acid derived urea peptidomimetics using phoxime resin. J Comb Chem. 1:1999;163-172.
    • (1999) J Comb Chem , vol.1 , pp. 163-172
    • Hamuro, Y.1    Marshall, W.J.2    Scialdone, M.A.3
  • 22
    • 0033518862 scopus 로고    scopus 로고
    • Resin-to-resin acyl- And aminoacyl-transfer reactions using oxime supports
    • Hamuro Y., Scialdone M.A., DeGrado W.F. Resin-to-resin acyl- and aminoacyl-transfer reactions using oxime supports. J Am Chem Soc. 121:1999;1636-1644.
    • (1999) J Am Chem Soc , vol.121 , pp. 1636-1644
    • Hamuro, Y.1    Scialdone, M.A.2    DeGrado, W.F.3
  • 24
    • 0033553497 scopus 로고    scopus 로고
    • Novel synthesis of oxindole quinazolines using solid phase multiparallel chemistry
    • Hennequin L.F., Peva-LeBlanc S. Novel synthesis of oxindole quinazolines using solid phase multiparallel chemistry. Tetrahedron Lett. 40:1999;3881-3884.
    • (1999) Tetrahedron Lett , vol.40 , pp. 3881-3884
    • Hennequin, L.F.1    Peva-Leblanc, S.2
  • 26
    • 0033547932 scopus 로고    scopus 로고
    • Parallel synthesis of 2-alkoxy- And 2-acyloxyphenylpropyl amides and amines using dihydrocoumarins as versatile synthons. Application of a novel resin quench-capture method
    • Bussolari J.C., Rehborn D.C., Combs D.W. Parallel synthesis of 2-alkoxy- and 2-acyloxyphenylpropyl amides and amines using dihydrocoumarins as versatile synthons. Application of a novel resin quench-capture method. Tetrahedron Lett. 40:1999;1241-1244.
    • (1999) Tetrahedron Lett , vol.40 , pp. 1241-1244
    • Bussolari, J.C.1    Rehborn, D.C.2    Combs, D.W.3
  • 27
    • 0033054018 scopus 로고    scopus 로고
    • Parallel synthesis of polyethylene glycol supported biaryl benzimidazoles and imidazopyridines
    • Blettner C.G., Koenig W.A., Ruehter G., Stenzel W., Schotten T. Parallel synthesis of polyethylene glycol supported biaryl benzimidazoles and imidazopyridines. Synlett. 1999;307-310.
    • (1999) Synlett , pp. 307-310
    • Blettner, C.G.1    Koenig, W.A.2    Ruehter, G.3    Stenzel, W.4    Schotten, T.5
  • 28
    • 0033524872 scopus 로고    scopus 로고
    • Parallel synthesis of 1,2,3-thiadiazoles employing a 'catch and release' strategy
    • Hu Y., Baudart S., Porco J.A. Jr. Parallel synthesis of 1,2,3-thiadiazoles employing a 'catch and release' strategy. J Org Chem. 64:1999;1049-1051.
    • (1999) J Org Chem , vol.64 , pp. 1049-1051
    • Hu, Y.1    Baudart, S.2    Porco J.A., Jr.3
  • 29
    • 0002519527 scopus 로고    scopus 로고
    • Preparation of designer resins via living free radical polymerization of functional monomers on solid support
    • This article describes the preparation of novel resins specifically tailored for use as scavengers in parallel solution-phase chemistry
    • Hodges J.C., Harikrishnan L.S., Ault-Justus S. Preparation of designer resins via living free radical polymerization of functional monomers on solid support. J Comb Chem. 2:2000;80-88. This article describes the preparation of novel resins specifically tailored for use as scavengers in parallel solution-phase chemistry.
    • (2000) J Comb Chem , vol.2 , pp. 80-88
    • Hodges, J.C.1    Harikrishnan, L.S.2    Ault-Justus, S.3
  • 31
    • 0033574494 scopus 로고    scopus 로고
    • Organic-fluorous phase switches: A fluorous amine scavenger for purification in solution phase parallel synthesis
    • Linclau B., Singh A.K., Curran D.P. Organic-fluorous phase switches: a fluorous amine scavenger for purification in solution phase parallel synthesis. J Org Chem. 64:1999;2835-2842.
    • (1999) J Org Chem , vol.64 , pp. 2835-2842
    • Linclau, B.1    Singh, A.K.2    Curran, D.P.3
  • 32
    • 0031029886 scopus 로고    scopus 로고
    • Fluorous synthesis: A fluorous-phase strategy for improving separation efficiency in organic synthesis
    • Studer A., Hadida S., Ferritto R., Kim S-Y., Jeger P., Wipf P., Curran D.P. Fluorous synthesis: a fluorous-phase strategy for improving separation efficiency in organic synthesis. Science. 275:1997;823-826.
    • (1997) Science , vol.275 , pp. 823-826
    • Studer, A.1    Hadida, S.2    Ferritto, R.3    Kim, S.-Y.4    Jeger, P.5    Wipf, P.6    Curran, D.P.7
  • 33
    • 0032884398 scopus 로고    scopus 로고
    • Parallel synthesis with fluorous reagents and reactants
    • Curran D.P. Parallel synthesis with fluorous reagents and reactants. Med Res Rev. 19:1999;432-438.
    • (1999) Med Res Rev , vol.19 , pp. 432-438
    • Curran, D.P.1
  • 34
    • 0033570055 scopus 로고    scopus 로고
    • New methodology for high throughput solution-phase synthesis: Affinity purification by using crown ether and ammonium ion interaction
    • Zhang S-Q., Fukase K., Kusumoto S. New methodology for high throughput solution-phase synthesis: affinity purification by using crown ether and ammonium ion interaction. Tetrahedron Lett. 40:1999;7479-7483.
    • (1999) Tetrahedron Lett , vol.40 , pp. 7479-7483
    • Zhang, S.-Q.1    Fukase, K.2    Kusumoto, S.3
  • 36
    • 0027282389 scopus 로고
    • Total synthesis of +/- bruceantin
    • Vander Roest J.M., Grieco P.A. Total synthesis of +/- bruceantin. J Am Chem Soc. 115:1993;5841-5842.
    • (1993) J Am Chem Soc , vol.115 , pp. 5841-5842
    • Vander Roest, J.M.1    Grieco, P.A.2
  • 37
    • 0002889029 scopus 로고    scopus 로고
    • Chameleon catches in combinatorial chemistry: Tebbe olefination of polymer supported esters and the synthesis of amines, cyclohexanones, enones, methyl ketones and thiazoles
    • Ball C.P., Barrett A.G.M., Compere D., Kuhn C., Roberts R.S., Smith M.L., Venier O., Commercon A. Chameleon catches in combinatorial chemistry: Tebbe olefination of polymer supported esters and the synthesis of amines, cyclohexanones, enones, methyl ketones and thiazoles. Chem Commun. 1998;2019-2020.
    • (1998) Chem Commun , pp. 2019-2020
    • Ball, C.P.1    Barrett, A.G.M.2    Compere, D.3    Kuhn, C.4    Roberts, R.S.5    Smith, M.L.6    Venier, O.7    Commercon, A.8
  • 38
    • 0033534495 scopus 로고    scopus 로고
    • Polymer-assisted solution phase synthesis: A general method for sequestration of byproducts formed from activated acyl-transfer reactants
    • Weidner J.J., Parlow J.J., Flynn D.L. Polymer-assisted solution phase synthesis: a general method for sequestration of byproducts formed from activated acyl-transfer reactants. Tetrahedron Lett. 40:1999;239-242.
    • (1999) Tetrahedron Lett , vol.40 , pp. 239-242
    • Weidner, J.J.1    Parlow, J.J.2    Flynn, D.L.3
  • 39
    • 0033527709 scopus 로고    scopus 로고
    • Remarkable three-step-one-pot solution phase preparation of novel imidazolines utilizing a UDC (Ugi/de-Boc/cyclize) strategy
    • Hulme C., Ma L., Romano J., Morrissette M. Remarkable three-step-one-pot solution phase preparation of novel imidazolines utilizing a UDC (Ugi/de-Boc/cyclize) strategy. Tetrahedron Lett. 40:1999;7925-7928.
    • (1999) Tetrahedron Lett , vol.40 , pp. 7925-7928
    • Hulme, C.1    Ma, L.2    Romano, J.3    Morrissette, M.4
  • 40
    • 0033601435 scopus 로고    scopus 로고
    • Protocols for amide high-speed analoging. Preparation of novel, small molecule cathepsin D inhibitors
    • Chen J., Dixon B.R., Dumas J., Brittelli D. Protocols for amide high-speed analoging. Preparation of novel, small molecule cathepsin D inhibitors. Tetrahedron Lett. 40:1999;9195-9199.
    • (1999) Tetrahedron Lett , vol.40 , pp. 9195-9199
    • Chen, J.1    Dixon, B.R.2    Dumas, J.3    Brittelli, D.4
  • 41
    • 0033584180 scopus 로고    scopus 로고
    • Design and synthesis of β-carboxamido phosphonates as potent inhibitors of imidazole glycerol phosphate dehydratase
    • Schweitzer B.A., Loida P.J., Thompson-Mize R.L., Cajacob C.A., Hegde S.G. Design and synthesis of β-carboxamido phosphonates as potent inhibitors of imidazole glycerol phosphate dehydratase. BioMed Chem Lett. 9:1999;2053-2058.
    • (1999) BioMed Chem Lett , vol.9 , pp. 2053-2058
    • Schweitzer, B.A.1    Loida, P.J.2    Thompson-Mize, R.L.3    Cajacob, C.A.4    Hegde, S.G.5
  • 42
    • 0033515672 scopus 로고    scopus 로고
    • Solution phase combinatorial synthesis of biaryl libraries employing heterogeneous conditions for catalysis and isolation with size exclusion chromatography for purification
    • Boger D.L., Goldberg J., Andersson C-M. Solution phase combinatorial synthesis of biaryl libraries employing heterogeneous conditions for catalysis and isolation with size exclusion chromatography for purification. J Org Chem. 64:1999;2422-2427.
    • (1999) J Org Chem , vol.64 , pp. 2422-2427
    • Boger, D.L.1    Goldberg, J.2    Andersson, C.-M.3
  • 44
    • 33748719848 scopus 로고    scopus 로고
    • Clean five-step synthesis of an array of 1,2,3,4-tetra-substituted pyrroles using polymer-supported reagents
    • This article describes the multistep sythesis of highly substituted pyrroles using PASP chemistry
    • Caldarelli M., Habermann J., Ley S.V. Clean five-step synthesis of an array of 1,2,3,4-tetra-substituted pyrroles using polymer-supported reagents. J Chem Soc Perkin Trans. 1999;107-110. This article describes the multistep sythesis of highly substituted pyrroles using PASP chemistry.
    • (1999) J Chem Soc Perkin Trans , pp. 107-110
    • Caldarelli, M.1    Habermann, J.2    Ley, S.V.3
  • 45
    • 0033584197 scopus 로고    scopus 로고
    • Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents
    • Caldarelli M., Habermann J., Ley S.V. Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents. Bioorg Med Chem Lett. 9:1999;2049-2052.
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 2049-2052
    • Caldarelli, M.1    Habermann, J.2    Ley, S.V.3
  • 46
    • 33746467034 scopus 로고    scopus 로고
    • Synthesis of the potent analgesic compound (±)-epibatidine using an orchestrated multi-step sequence of polymer supported reagents
    • A ten-step synthesis of a complete natural product using both PASP reagents and purification
    • Habermann J., Ley S.V., Scott J.S. Synthesis of the potent analgesic compound (±)-epibatidine using an orchestrated multi-step sequence of polymer supported reagents. J Chem Soc Perkin Trans. 1999;1253-1256. A ten-step synthesis of a complete natural product using both PASP reagents and purification.
    • (1999) J Chem Soc Perkin Trans , pp. 1253-1256
    • Habermann, J.1    Ley, S.V.2    Scott, J.S.3


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