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Volumn 32, Issue 1, 1999, Pages 18-26

Solid-supported reagent strategies for rapid purification of combinatorial synthesis products

Author keywords

[No Author keywords available]

Indexed keywords

REAGENT; RESIN;

EID: 0032948663     PISSN: 00014842     EISSN: None     Source Type: Journal    
DOI: 10.1021/ar970311n     Document Type: Article
Times cited : (212)

References (27)
  • 1
    • 0000951677 scopus 로고
    • Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid
    • Geysen, H. M.; Meloen, R. H.; Barteling, S. J. Use of Peptide Synthesis to Probe Viral Antigens for Epitopes to a Resolution of a Single Amino Acid. Proc. Natl. Acad. Sci. U.S.A. 1984, 81, 3998-4002.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 3998-4002
    • Geysen, H.M.1    Meloen, R.H.2    Barteling, S.J.3
  • 2
    • 0000478940 scopus 로고
    • General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids
    • Houghten, R. A. General Method for the Rapid Solid-Phase Synthesis of Large Numbers of Peptides: Specificity of Antigen-Antibody Interaction at the level of Individual Amino Acids. Proc. Natl. Aca. Sci. U.S.A. 1985, 82, 5131.
    • (1985) Proc. Natl. Aca. Sci. U.S.A. , vol.82 , pp. 5131
    • Houghten, R.A.1
  • 3
    • 0025893762 scopus 로고
    • General method for rapid synthesis of multicomponent peptide mixtures
    • Furka, A.; Sebestyen, F.; Asgedom, M.; Dibo, G. General Method for Rapid Synthesis of Multicomponent Peptide Mixtures. Int. J. Pept. Protein Res. 1991, 37, 487-93.
    • (1991) Int. J. Pept. Protein Res. , vol.37 , pp. 487-493
    • Furka, A.1    Sebestyen, F.2    Asgedom, M.3    Dibo, G.4
  • 4
    • 0026419328 scopus 로고
    • A new type of synthetic peptide library for identifying ligand-binding activity
    • Lam, K. S.; Salmon, S. E.; Hersh, E. M.; Hruby, V. J.; Kazmierski, W. M.; Knapp, R. J. A New Type of Synthetic Peptide Library for Identifying Ligand-Binding Activity. Nature 1991, 354, 82-4.
    • (1991) Nature , vol.354 , pp. 82-84
    • Lam, K.S.1    Salmon, S.E.2    Hersh, E.M.3    Hruby, V.J.4    Kazmierski, W.M.5    Knapp, R.J.6
  • 5
    • 0029930278 scopus 로고    scopus 로고
    • Solid-phase organic reactions: A review of the recent literature
    • Hermkens, P. H. H.; Ottenheijm, H. C. J.; Rees, D. Solid-Phase Organic Reactions: A Review of the Recent Literature. Tetrahedron 1996, 52, 4527-54.
    • (1996) Tetrahedron , vol.52 , pp. 4527-4554
    • Hermkens, P.H.H.1    Ottenheijm, H.C.J.2    Rees, D.3
  • 6
    • 0031001699 scopus 로고    scopus 로고
    • Solid-phase organic reactions. II: A review of the literature Nov 95-Nov 96
    • Hermkens, P. H. H.; Ottenheijm, H. C. J.; Rees, D. C. Solid-Phase Organic Reactions. II: A Review of the Literature Nov 95-Nov 96. Tetrahedron 1997, 53, 5643-5678.
    • (1997) Tetrahedron , vol.53 , pp. 5643-5678
    • Hermkens, P.H.H.1    Ottenheijm, H.C.J.2    Rees, D.C.3
  • 7
    • 0030607141 scopus 로고    scopus 로고
    • Use of solid supported nucleophiles and electrophiles for the purification of nonpeptide small molecule libraries
    • Kaldor, S. W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Use of Solid Supported Nucleophiles and Electrophiles for the Purification of Nonpeptide Small Molecule libraries. Tetrahedron Lett. 1996, 37, 7193-7196.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 7193-7196
    • Kaldor, S.W.1    Siegel, M.G.2    Fritz, J.E.3    Dressman, B.A.4    Hahn, P.J.5
  • 8
    • 0030987922 scopus 로고    scopus 로고
    • Polymer-supported quenching reagents for parallel purification
    • Booth, R. J.; Hodges, J. C. Polymer-Supported Quenching Reagents for Parallel Purification. J. Am. Chem. Soc. 1997, 119, 4882-4886.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 4882-4886
    • Booth, R.J.1    Hodges, J.C.2
  • 9
    • 0030952762 scopus 로고    scopus 로고
    • Chemical library purification strategies based on principles of complementary molecular reactivity and molecular recognition
    • Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S.Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition. J. Am. Chem. Soc. 1997, 119, 4874-4881.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 4874-4881
    • Flynn, D.L.1    Crich, J.Z.2    Devraj, R.V.3    Hockerman, S.L.4    Parlow, J.J.5    South, M.S.6    Woodard, S.7
  • 10
    • 0031576842 scopus 로고    scopus 로고
    • Solution-phase combinatorial synthesis via the Olefin metathesis reaction
    • A notable exception to this general rule is found in the following reference where chromatography is used to separate mixtures of starting materials from mixtures of products: Boger, D. L.; Chai, W.; Ozer, R. S.; Anderson, C.-M. Solution-Phase Combinatorial Synthesis via the Olefin Metathesis Reaction. Bioorg. Med. Chem. Lett. 1997, 7, 463-468.
    • (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 463-468
    • Boger, D.L.1    Chai, W.2    Ozer, R.S.3    Anderson, C.-M.4
  • 11
    • 85069026207 scopus 로고    scopus 로고
    • Strategies for parallel purification of combinatorial synthesis products
    • San Francisco, April 13-17; American Chemical Society, Washington, DC, Abstract ORGN-380
    • Hodges, J. C.; Booth, R. J.; Creswell, M. W.; Wilson, M. W.; Warmus, J. S. Strategies for Parallel Purification of Combinatorial Synthesis Products. Book of Abstracts, 213th ACS National Meeting, San Francisco, April 13-17; American Chemical Society, Washington, DC, 1997; Abstract ORGN-380.
    • (1997) Book of Abstracts, 213th ACS National Meeting
    • Hodges, J.C.1    Booth, R.J.2    Creswell, M.W.3    Wilson, M.W.4    Warmus, J.S.5
  • 12
    • 0001221180 scopus 로고
    • New probes for the study of acylation reactions
    • Rebek, J.; Brown, D.; Zimmerman, S. New Probes for the Study of Acylation Reactions. J. Am. Chem. Soc. 1975, 97, 4407-8.
    • (1975) J. Am. Chem. Soc. , vol.97 , pp. 4407-4408
    • Rebek, J.1    Brown, D.2    Zimmerman, S.3
  • 13
    • 0000114532 scopus 로고
    • The use of polymer supports in organic synthesis. XI. The preparation of monoethers of symmetrical dihydroxy aromatic compounds
    • Leznoff, C. C.; Dixit, D. M. The Use of Polymer Supports in Organic Synthesis. XI. The Preparation of Monoethers of Symmetrical Dihydroxy Aromatic Compounds. Can. J. Chem. 1977, 55, 3351-5.
    • (1977) Can. J. Chem. , vol.55 , pp. 3351-3355
    • Leznoff, C.C.1    Dixit, D.M.2
  • 14
    • 0030813190 scopus 로고    scopus 로고
    • In situ chemical tagging: Tetrafluorophthalic anhydride as a "sequestration enabling reagent" (SER) in the purification of solution-phase combinatorial libraries
    • Parlow, J. J.; Naing, W.; South, M. S.; Flynn, D. L. In situ Chemical Tagging: Tetrafluorophthalic Anhydride as a "Sequestration Enabling Reagent" (SER) in the Purification of Solution-Phase Combinatorial Libraries. Tetrahedron Lett. 1997, 30, 7959-7962.
    • (1997) Tetrahedron Lett. , vol.30 , pp. 7959-7962
    • Parlow, J.J.1    Naing, W.2    South, M.S.3    Flynn, D.L.4
  • 15
    • 0001768317 scopus 로고    scopus 로고
    • Utility of complementary molecular reactivity and molecular recognition (CMR/R) technology and polymer-supported reagents in the solution-phase synthesis of heterocyclic carboxamides
    • Parlow, J. J.; Mischke, D. A.; Woodard, S. S. Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Technology and Polymer-Supported Reagents in the Solution-Phase Synthesis of Heterocyclic Carboxamides. J. Org. Chem. 1997, 62, 5908-5919.
    • (1997) J. Org. Chem. , vol.62 , pp. 5908-5919
    • Parlow, J.J.1    Mischke, D.A.2    Woodard, S.S.3
  • 18
    • 0032537040 scopus 로고    scopus 로고
    • Combinatorial synthesis of dihydropyridone libraries and their derivatives
    • Creswell, M. W.; Bolton, G. L.; C., H. J.; Meppen, M. Combinatorial Synthesis of Dihydropyridone Libraries and their Derivatives. Tetrahedron (Symposia-in-Print) 1998, 54, 3983-3998.
    • (1998) Tetrahedron (Symposia-in-print) , vol.54 , pp. 3983-3998
    • Creswell, M.W.1    Bolton, G.L.2    C, H.J.3    Meppen, M.4
  • 19
    • 0030591840 scopus 로고    scopus 로고
    • Discovery of antirhinoviral leads by screening a combinatorial library of ureas prepared using covalent scavengers
    • Kaldor, S. W.; Fritz, J. E.; Tang, J.; McKinney, E. R. Discovery of Antirhinoviral Leads by Screening a Combinatorial Library of Ureas Prepared using Covalent Scavengers. Bioorg. Med. Chem. Lett. 1996, 6, 3041-3044.
    • (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 3041-3044
    • Kaldor, S.W.1    Fritz, J.E.2    Tang, J.3    McKinney, E.R.4
  • 20
    • 0032403246 scopus 로고    scopus 로고
    • Generation of a library of 4-thiazolidinones utilizing polymer supported Quench (PSQ) reagent methodology
    • Ault-Justus, S. E.; Hodges, J. C.; Wilson, M. W. Generation of a Library of 4-Thiazolidinones Utilizing Polymer Supported Quench (PSQ) Reagent Methodology. Biotechnol. Bioeng. 1998, 1, 17-22.
    • (1998) Biotechnol. Bioeng. , vol.1 , pp. 17-22
    • Ault-Justus, S.E.1    Hodges, J.C.2    Wilson, M.W.3
  • 21
    • 0032567966 scopus 로고    scopus 로고
    • Arylsulfonate esters in solid-phase organic synthesis. I. Cleavage with amines, thiolate, and imidazole
    • Rueter, J. K.; Nortey, S. O.; Baxter, E. W.; Leo, G. C.; Reitz, A. B. Arylsulfonate Esters in Solid-Phase Organic Synthesis. I. Cleavage with Amines, Thiolate, and Imidazole. Tetrahedron Lett. 1998, 39, 975-978.
    • (1998) Tetrahedron Lett. , vol.39 , pp. 975-978
    • Rueter, J.K.1    Nortey, S.O.2    Baxter, E.W.3    Leo, G.C.4    Reitz, A.B.5
  • 22
    • 0030873736 scopus 로고    scopus 로고
    • Nonacidic cleavage of wang-derived ethers from solid support: Utilization of a mixed-bed scavenger for DDQ
    • Deegan, T. L.; Gooding, O. W.; Baudart, S.; Proco, J. A., Jr. Nonacidic Cleavage of Wang-derived Ethers from Solid Support: Utilization of a Mixed-Bed Scavenger for DDQ. Tetrahedron Lett. 1997, 38, 4973-4976.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 4973-4976
    • Deegan, T.L.1    Gooding, O.W.2    Baudart, S.3    Proco J.A., Jr.4
  • 23
    • 0031029886 scopus 로고    scopus 로고
    • Fluorous synthesis: A fluorous-phase strategy for improving separation efficiency in organic synthesis
    • Studer, A.; Hadida, S.; Ferritto, F.; Kim, S.-Y.; Jeger, P.; Wipf, P.; Curran, D. P. Fluorous Synthesis: A Fluorous-Phase Strategy for Improving Separation Efficiency in Organic Synthesis. Science 1997, 275, 823-826.
    • (1997) Science , vol.275 , pp. 823-826
    • Studer, A.1    Hadida, S.2    Ferritto, F.3    Kim, S.-Y.4    Jeger, P.5    Wipf, P.6    Curran, D.P.7
  • 24
    • 0029926720 scopus 로고    scopus 로고
    • Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules
    • Cheng, S.; Comer, D. D.; Williams, J. P.; Myers, P. L.; Boger, D. L. Novel Solution Phase Strategy for the Synthesis of Chemical Libraries Containing Small Organic Molecules. J. Am. Chem. Soc. 1996, 118, (11), 2567-73.
    • (1996) J. Am. Chem. Soc. , vol.118 , Issue.11 , pp. 2567-2573
    • Cheng, S.1    Comer, D.D.2    Williams, J.P.3    Myers, P.L.4    Boger, D.L.5
  • 25
    • 0031021840 scopus 로고    scopus 로고
    • Ion-exchange resins for solution phase parallel synthesis of chemical libraries
    • (a) Gayo, L. M.; Suto, M. J. Ion-Exchange Resins for Solution Phase Parallel Synthesis of Chemical Libraries. Tetrahedron. Lett. 1997, 38, 513-516.
    • (1997) Tetrahedron. Lett. , vol.38 , pp. 513-516
    • Gayo, L.M.1    Suto, M.J.2
  • 26
    • 0030839735 scopus 로고    scopus 로고
    • The application of high-throughput synthesis and purification to the preparation of ethanolamines
    • (b) Shuker, A. J.; Siegel, M. G.; Matthews, D. P.; Weigel, Leland O. The Application of High-Throughput Synthesis and Purification to the Preparation of Ethanolamines. Tetrahedron. Lett. 1997, 38, 6149-6152.
    • (1997) Tetrahedron. Lett. , vol.38 , pp. 6149-6152
    • Shuker, A.J.1    Siegel, M.G.2    Matthews, D.P.3    Weigel, L.O.4
  • 27
    • 33947291827 scopus 로고
    • Solid-phase synthesis of oligosaccharides. I. Preparation of the solid support. Poly[p-(1-propen-3-ol-1-yl)styrene]
    • Frechet, J. M.; Schuerch, C. Solid-phase Synthesis of Oligosaccharides. I. Preparation of the Solid Support. Poly[p-(1-propen-3-ol-1-yl)styrene]. J. Am. Chem. Soc. 1971, 93 (3), 492-6.
    • (1971) J. Am. Chem. Soc. , vol.93 , Issue.3 , pp. 492-496
    • Frechet, J.M.1    Schuerch, C.2


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