Constitutive levels of cAMP-dependent protein kinase activity determine sensitivity of human multidrug-resistant leukaemic cell lines to growth inhibition and apoptosis by forskolin and tumour necrosis factor alpha

British Journal of Haematology

Volumn 108, Issue 3, 2000, Pages 565-573

  Yin, Yuzhi ^a   Allen, Paul D ^a   Jia, Li ^a   Macey, Marion G ^a   Kelsey, Stephen M ^a   Newland, Adrian C ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; cAMP; Leukaemia; MDR; PKA

Indexed keywords

8 CHLOROADENOSINE 3',5' PHOSPHATE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DAUNORUBICIN; DNA; FORSKOLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; TUMOR NECROSIS FACTOR ALPHA; VINBLASTINE;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MULTIDRUG RESISTANCE; PHENOTYPE; PRIORITY JOURNAL;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIVISION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; FORSKOLIN; HUMANS; ISOQUINOLINES; LEUKEMIA; NF-KAPPA B; P-GLYCOPROTEIN; SULFONAMIDES; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034111905     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.01903.x     Document Type: Article

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