-
1
-
-
0027858371
-
The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional-related diseases
-
Cho-Chung, Y. S., and Clair, T. The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional-related diseases. Pharmacol. Ther., 60: 265-288, 1993.
-
(1993)
Pharmacol. Ther.
, vol.60
, pp. 265-288
-
-
Cho-Chung, Y.S.1
Clair, T.2
-
2
-
-
0027456590
-
8-Cl-cAMP induces down-regulation of the RIα subunit and up-regulation of the RIIβ subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells
-
Rohlff, C., Clair, T., and Cho-Chung, Y. S. 8-Cl-cAMP induces down-regulation of the RIα subunit and up-regulation of the RIIβ subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells. J. Biol. Chem., 268: 5774-5782, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5774-5782
-
-
Rohlff, C.1
Clair, T.2
Cho-Chung, Y.S.3
-
3
-
-
0028172920
-
The RIα subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells
-
Tortora, G., Pepe, S., Bianco, C., Baldassarre, G., Budillon, A., Clair, T., Cho-Chung, Y. S., Bianco, A. R., and Ciardiello, F. The RIα subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells. Oncogene, 9: 3233-3240, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3233-3240
-
-
Tortora, G.1
Pepe, S.2
Bianco, C.3
Baldassarre, G.4
Budillon, A.5
Clair, T.6
Cho-Chung, Y.S.7
Bianco, A.R.8
Ciardiello, F.9
-
4
-
-
0025070111
-
8-Cl-cAMP inhibits transforming growth factor a transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase-regulatory subunit isoforms which show disruption upon transformation
-
Ciardiello, F., Tortora, G., Kim, N., Clair, T., Ally, S., Salomon, D. S., and Cho-Chung, Y. S. 8-Cl-cAMP inhibits transforming growth factor a transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase-regulatory subunit isoforms which show disruption upon transformation. J. Biol. Chem., 265: 1016-1020, 1990.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 1016-1020
-
-
Ciardiello, F.1
Tortora, G.2
Kim, N.3
Clair, T.4
Ally, S.5
Salomon, D.S.6
Cho-Chung, Y.S.7
-
5
-
-
0027499522
-
Down-regulation of RIα subunit of the cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-crbB-2 proto-oncogenes
-
Ciardiello, F., Pepe, S., Bianco, C., Baldassarre, G., Ruggiero, A., Bianco, C., Selvam, M. P., Bianco, A. R., and Tortora, G. Down-regulation of RIα subunit of the cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-crbB-2 proto-oncogenes. Int. J. Cancer, 53: 438-443, 1993.
-
(1993)
Int. J. Cancer
, vol.53
, pp. 438-443
-
-
Ciardiello, F.1
Pepe, S.2
Bianco, C.3
Baldassarre, G.4
Ruggiero, A.5
Bianco, C.6
Selvam, M.P.7
Bianco, A.R.8
Tortora, G.9
-
6
-
-
0030614954
-
The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF receptor
-
Tortora, G., Damiano, V., Bianco, C., Baldassarre, G., Bianco, A. R., Lanfrancone, L., Pelicci, P. G., and Ciardiello, F. The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF receptor. Oncogene, 14: 9223-9224, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 9223-9224
-
-
Tortora, G.1
Damiano, V.2
Bianco, C.3
Baldassarre, G.4
Bianco, A.R.5
Lanfrancone, L.6
Pelicci, P.G.7
Ciardiello, F.8
-
7
-
-
0024353952
-
Site-selective 8-chloro-cyclic adenosine 3′,5′-monophosphate as a biological modulator of cancer: Restoration of normal control mechanisms
-
Cho-Chung, Y. S. Site-selective 8-chloro-cyclic adenosine 3′,5′-monophosphate as a biological modulator of cancer: restoration of normal control mechanisms. J. Natl. Cancer Inst., 81: 981-987, 1989.
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 981-987
-
-
Cho-Chung, Y.S.1
-
8
-
-
0024418926
-
Inhibition of growth and modulation of gene expression in human lung carcinoma in athymic mice by site-selective 8-Cl-cAMP
-
Ally, S., Clair, T., Katsaros, D., Tortora, G., Yokozaki, H., Finch, R. A., Avery, T. L., and Cho-Chung, Y. S. Inhibition of growth and modulation of gene expression in human lung carcinoma in athymic mice by site-selective 8-Cl-cAMP. Cancer Res., 49: 5650-5655, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5650-5655
-
-
Ally, S.1
Clair, T.2
Katsaros, D.3
Tortora, G.4
Yokozaki, H.5
Finch, R.A.6
Avery, T.L.7
Cho-Chung, Y.S.8
-
9
-
-
0029002725
-
Growth inhibition by 8-chloro-cyclic AMP of human HT29 colorectal and ZR-75-1 breast carcinoma xenografts is associated with selective modulation of protein kinase A isozymes
-
Ramage, A. D., Langdon, S. P., Ritchie, A., Burns, D. J., and Miller, W. R. Growth inhibition by 8-chloro-cyclic AMP of human HT29 colorectal and ZR-75-1 breast carcinoma xenografts is associated with selective modulation of protein kinase A isozymes. Eur. J. Cancer, 31A: 969-973, 1995.
-
(1995)
Eur. J. Cancer
, vol.31 A
, pp. 969-973
-
-
Ramage, A.D.1
Langdon, S.P.2
Ritchie, A.3
Burns, D.J.4
Miller, W.R.5
-
10
-
-
0027268671
-
8-Chloro-adenosine 3′,5′-monophosphate as a novel modulator of multidrug resistance
-
Yokozaki, H., Budillon, A., Clair, T., Kelley, K., Cowan, K., Rohlff, C., Glazer, R. I., and Cho-Chung, Y. S. 8-Chloro-adenosine 3′,5′-monophosphate as a novel modulator of multidrug resistance. Int. J. Oncol., 3: 423-430, 1993.
-
(1993)
Int. J. Oncol.
, vol.3
, pp. 423-430
-
-
Yokozaki, H.1
Budillon, A.2
Clair, T.3
Kelley, K.4
Cowan, K.5
Rohlff, C.6
Glazer, R.I.7
Cho-Chung, Y.S.8
-
11
-
-
0029091747
-
Down-regulation of mdr-1 expression by 8-Cl-cAMP in multidrug-resistant MCF-7 human breast cancer cells
-
Scala, S., Budillon, A., Zhan, Z., Cho-Chung, Y. S., Jefferson, J., Tsokos, M., and Bates, S. E. Down-regulation of mdr-1 expression by 8-Cl-cAMP in multidrug-resistant MCF-7 human breast cancer cells. J. Clin. Invest., 96: 1026-1034, 1995.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1026-1034
-
-
Scala, S.1
Budillon, A.2
Zhan, Z.3
Cho-Chung, Y.S.4
Jefferson, J.5
Tsokos, M.6
Bates, S.E.7
-
12
-
-
0028948435
-
Phase I clinical study with 8-chloro-cAMP and evaluation of immunologic effects in cancer patients
-
Tortora, G., Ciardiello, F., Pepe, S., Tagliaferri, P., Ruggiero, A., Bianco, C., Guarrasi, R., Miki, K., and Bianco, A. R. Phase I clinical study with 8-chloro-cAMP and evaluation of immunologic effects in cancer patients. Clin. Cancer Res., 1: 377-384, 1995.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 377-384
-
-
Tortora, G.1
Ciardiello, F.2
Pepe, S.3
Tagliaferri, P.4
Ruggiero, A.5
Bianco, C.6
Guarrasi, R.7
Miki, K.8
Bianco, A.R.9
-
13
-
-
0010592771
-
Phase I study of the protein kinase A regulator 8-chloro-cyclic AMP
-
Saunders, M. P., Salisbury, A. J., Harris, A. L., Long, L., O' Byrne, K. J., Macaulay, V. M., Miki, K., Cho-Chung, Y. S., and Talbot, D. C. Phase I study of the protein kinase A regulator 8-chloro-cyclic AMP. Proc. Am. Assoc. Cancer Res., 36: 241, 1995.
-
(1995)
Proc. Am. Assoc. Cancer Res.
, vol.36
, pp. 241
-
-
Saunders, M.P.1
Salisbury, A.J.2
Harris, A.L.3
Long, L.4
O' Byrne, K.J.5
Macaulay, V.M.6
Miki, K.7
Cho-Chung, Y.S.8
Talbot, D.C.9
-
14
-
-
0028917189
-
Cooperative antiproliferative effects of 8-Cl-cAMP and 528 anti-epidermal growth factor receptor monoclonal antibody on human cancer cells
-
Ciardiello, F., Damiano, V., Bianco, C., di Isernia, G., Ruggiero, A., Caraglia, M., Tagliaferri, P., Baselga, J., Mendelsohn, J., Bianco, A. R., and Tortora, G. Cooperative antiproliferative effects of 8-Cl-cAMP and 528 anti-epidermal growth factor receptor monoclonal antibody on human cancer cells. Clin. Cancer Res., 1: 161-167, 1995.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 161-167
-
-
Ciardiello, F.1
Damiano, V.2
Bianco, C.3
Di Isernia, G.4
Ruggiero, A.5
Caraglia, M.6
Tagliaferri, P.7
Baselga, J.8
Mendelsohn, J.9
Bianco, A.R.10
Tortora, G.11
-
15
-
-
16144362509
-
Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A
-
Ciardiello, F., Damiano V., Bianco, R., Bianco, C., Fontanini, G., De Laurentiis, M., De Placido, S., Mendelsohn, J., Bianco, A. R., and Tortora, G. Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A. J. Natl. Cancer Inst., 88: 1770-1776, 1996.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 1770-1776
-
-
Ciardiello, F.1
Damiano, V.2
Bianco, R.3
Bianco, C.4
Fontanini, G.5
De Laurentiis, M.6
De Placido, S.7
Mendelsohn, J.8
Bianco, A.R.9
Tortora, G.10
-
16
-
-
0029824819
-
8-Chloro-cAMP enhances the growth-inhibitory effect of cytotoxic drugs in human colon cancer cells
-
di Isernia, G., Ciardiello, F., Sandomenico, C., Pepe, S., Bianco, A. R., and Tortora, G. 8-Chloro-cAMP enhances the growth-inhibitory effect of cytotoxic drugs in human colon cancer cells. Int. J. Oncol., 9: 1233-1237, 1996.
-
(1996)
Int. J. Oncol.
, vol.9
, pp. 1233-1237
-
-
Di Isernia, G.1
Ciardiello, F.2
Sandomenico, C.3
Pepe, S.4
Bianco, A.R.5
Tortora, G.6
-
17
-
-
0027740084
-
Activin A induces apoptotic cell death
-
Nishihara, T., Okahashi, T., and Ueda, N. Activin A induces apoptotic cell death. Biochem. Biophys. Res. Commun., 2: 985-991, 1993.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.2
, pp. 985-991
-
-
Nishihara, T.1
Okahashi, T.2
Ueda, N.3
-
18
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods, 139: 271-279, 1991.
-
(1991)
J. Immunol. Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
19
-
-
0002845244
-
Anti-Her2 humanized monoclonal antibody alone and in combination with chemotherapy against human breast carcinoma xenografts
-
Baselga, J., Norton, L., Shalaby, R., and Mendelsohn, J. Anti-Her2 humanized monoclonal antibody alone and in combination with chemotherapy against human breast carcinoma xenografts. Proc. Am. Soc. Clin. Oncol., 13: 63, 1994.
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.13
, pp. 63
-
-
Baselga, J.1
Norton, L.2
Shalaby, R.3
Mendelsohn, J.4
-
20
-
-
0027290650
-
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
-
Baselga, J., Norton, L., Masui, H., Pandiella, A., Coplan, K., Miller, W. H., and Mendelsohn, J. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J. Natl. Cancer Inst., 85: 1327-1333, 1993.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 1327-1333
-
-
Baselga, J.1
Norton, L.2
Masui, H.3
Pandiella, A.4
Coplan, K.5
Miller, W.H.6
Mendelsohn, J.7
-
21
-
-
0027428571
-
Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well-established A431 cell xenografts
-
Fan, Z., Baselga, J., Masui, H., and Mendelsohn, J. Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well-established A431 cell xenografts. Cancer Res., 53: 4637-4642, 1992.
-
(1992)
Cancer Res.
, vol.53
, pp. 4637-4642
-
-
Fan, Z.1
Baselga, J.2
Masui, H.3
Mendelsohn, J.4
-
23
-
-
0023880224
-
Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs
-
Tagliaferri, P., Katsaros, D., Clair, T., Neckers, L., Robins, R. K., and Cho-Chung, Y. S. Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs. J. Biol. Chem., 5: 409-416 1988.
-
(1988)
J. Biol. Chem.
, vol.5
, pp. 409-416
-
-
Tagliaferri, P.1
Katsaros, D.2
Clair, T.3
Neckers, L.4
Robins, R.K.5
Cho-Chung, Y.S.6
-
24
-
-
0021325726
-
Two classes of cAMP analogs which are selective for the two different cAMP binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes
-
Beebe, S. S., Holloway, R., Rannels, S. R., and Corbin, J. D. Two classes of cAMP analogs which are selective for the two different cAMP binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes. J. Biol. Chem., 259: 3539-3547, 1984.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 3539-3547
-
-
Beebe, S.S.1
Holloway, R.2
Rannels, S.R.3
Corbin, J.D.4
-
25
-
-
0030888688
-
8-Chloro-cAMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer
-
Bianco, C., Tortora, G., Baldassarre, G., Caputo, R., Fontanini, G., Chiǹe. S., Bianco, A. R., and Ciardiello, F. 8-Chloro-cAMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer. Clin. Cancer Res., 3: 439-448, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 439-448
-
-
Bianco, C.1
Tortora, G.2
Baldassarre, G.3
Caputo, R.4
Fontanini, G.5
Chiǹe, S.6
Bianco, A.R.7
Ciardiello, F.8
-
26
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid, and other diseases
-
Folkman, S. Angiogenesis in cancer, vascular, rheumatoid, and other diseases. Nat. Med., 1: 27-31, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, S.1
-
27
-
-
0002861227
-
Principles of molecular cell biology of cancer: Growth factors
-
V. T. DeVita, S. Hellman. and S. A. Rosenberg (eds.), Philadelphia: J. B. Lippincott Co.
-
Mendelsohn, J., and Lippman, M. E. Principles of molecular cell biology of cancer: growth factors. In: V. T. DeVita, S. Hellman. and S. A. Rosenberg (eds.), Cancer: Principles and Practice of Oncology, pp. 114-133. Philadelphia: J. B. Lippincott Co., 1993.
-
(1993)
Cancer: Principles and Practice of Oncology
, pp. 114-133
-
-
Mendelsohn, J.1
Lippman, M.E.2
-
28
-
-
0028200221
-
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
-
Pietras, R. J., Fendly, B. M., Chazin, V. R., Pegram, M. D., Howell, S. B., and Slamon, D. J. Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene, 9: 1829-1838, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1829-1838
-
-
Pietras, R.J.1
Fendly, B.M.2
Chazin, V.R.3
Pegram, M.D.4
Howell, S.B.5
Slamon, D.J.6
-
29
-
-
0028167813
-
c-erbB-2 signaling enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: Association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair
-
c-erbB-2 signaling enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair. Cancer Res., 54: 3758-3765, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3758-3765
-
-
Arteaga, C.L.1
Winnier, A.R.2
Poirier, M.C.3
Lopez-Larraza, D.M.4
Shawver, L.K.5
Hurd, S.D.6
Stewart, S.J.7
-
30
-
-
0030860337
-
Antisense-protein kinase A: A single-gene-based therapeutic approach
-
Cho-Chung, Y. S., Nesterova, M., Kondrashin, A., Noguchi, K., Srivastava, R., and Pepe, S. Antisense-protein kinase A: a single-gene-based therapeutic approach. Antisense & Nucleic Acid Drug Dev., 7: 217-223, 1997.
-
(1997)
Antisense & Nucleic Acid Drug Dev.
, vol.7
, pp. 217-223
-
-
Cho-Chung, Y.S.1
Nesterova, M.2
Kondrashin, A.3
Noguchi, K.4
Srivastava, R.5
Pepe, S.6
|