Apoptosis induction by a dopaminergic neurotoxin, 1-methyl-4-phenylpyridinium ion (MPP+), and inhibition by epidermal growth factor in GH3 cells

Biochemical Pharmacology

Volumn 60, Issue 1, 2000, Pages 111-120

  Yoshinaga, Norihiro ^a   Murayama, Toshihiko ^a   Nomura, Yasuyuki ^a  

^a Grad Sch Pharmaceutical Sci   (Japan)

Author keywords

Apoptosis; Caspase; Cytochrome c; Dopaminergic neurotoxin; EGF; GH3 cells; MPP+

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 4 (3 CHLOROANILINO) 6,7 DIMETHOXXYQUINOXALINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ACETYLCYSTEINE; ANTIOXIDANT; CASPASE INHIBITOR; CYTOCHROME C; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; NEUROTOXIN; PROTEIN BCL 2; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL STRAIN GH3; CONTROLLED STUDY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; IMMUNOBLOTTING; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT;

1-METHYL-4-PHENYLPYRIDINIUM; ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; CYTOCHROME C GROUP; DNA FRAGMENTATION; DRUG INTERACTIONS; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; FREE RADICAL SCAVENGERS; MITOCHONDRIA; PROTECTIVE AGENTS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 0034107787     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00304-X     Document Type: Article

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