Chemokine receptor CCR5 and CXCR4 expression in HIV-associated kidney disease

Journal of the American Society of Nephrology

Volumn 11, Issue 5, 2000, Pages 856-867

  Eitner, Frank ^a   Cui, Yan ^a   Hudkins, Kelly L ^a   Stokes, Michael B ^a   Segerer, Stephan ^b   Mack, Matthias ^b   Lewis, Paul L ^c   Abraham, A Andrew ^d   Schlöndorff, Detlef ^b   Gallo, Gloria ^e   Kimmel, Paul L ^f   Alpers, Charles E ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4;

ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE EXPRESSION; GENE LOCATION; GLOMERULOPATHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNE COMPLEX NEPHRITIS; KIDNEY DISEASE; KIDNEY PARENCHYMA; PRIORITY JOURNAL; THROMBOTIC THROMBOCYTOPENIC PURPURA;

EID: 0034091977     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Winston JA, Klotman PE: Are we missing an epidemic of HIV-associated nephropathy? J Am Soc Nephrol 7: 1-7, 1996
2. D'Agati V, Appel GB: HIV infection and the kidney. J Am Soc Nephrol 8: 138-152, 1997
3. Schwartz EJ, Klotman PE: Pathogenesis of human immunodeficiency virus (HIV)-associated nephropathy. Semin Nephrol 18: 436-445, 1998
4. Rao TK: Renal complications in HIV disease. Med Clin North Am 80: 1437-1451, 1996
5. D'Agati V, Appel GB: Renal pathology of human immunodeficiency virus infection. Semin Nephrol 18: 406-421, 1998
6. Humphreys MH: Human immunodeficiency virus-associated glomerulosclerosis. Kidney Int 48: 311-320, 1995
7. Kimmel PL, Phillips TM, Ferreira-Centeno A, Farkas-Szallasi T, Abraham AA, Garrett CT: HIV-associated immune-mediated renal disease. Kidney Int 44: 1327-1340, 1993
8. Stokes MB, Chawla H, Brody RI, Kumar A, Gertner R, Goldfarb DS, Gallo G: Immune complex glomerulonephritis in patients coinfected with human immunodeficiency virus and hepatitis C virus. Am J Kidney Dis 29: 514-525, 1997
9. Kimmel PL, Phillips TM, Ferreira-Centeno A, Farkas-Szallasi T, Abraham AA, Garrett CT: Brief report: Idiotypic IgA nephropathy in patients with human immunodeficiency virus infection. N Engl J Med 327: 702-706, 1992
10. Hymes KB, Karpatkin S: Human immunodeficiency virus infection and thrombotic microangiopathy. Semin Hematol 34: 117-125, 1997
11. Ruggenenti P, Lutz J, Remuzzi G: Pathogenesis and treatment of thrombotic microangiopathy. Kidney Int Suppl 58: S97-S101, 1997
12. Cohen AH, Nast CC: HIV-associated nephropathy: A unique combined glomerular, tubular, and interstitial lesion. Mod Pathol 1: 87-97, 1988
13. D'Agati V, Suh JI, Carbone L, Cheng JT, Appel G: Pathology of HIV-associated nephropathy: A detailed morphologic and comparative study. Kidney Int 35: 1358-1370, 1989
14. Bodi I, Abraham AA, Kimmel PL: Macrophages in human immunodeficiency virus-associated kidney diseases. Am J Kidney Dis 24: 762-767, 1994
15. Doms RW, Peiper SC: Unwelcomed guests with master keys: How HIV uses chemokine receptors for cellular entry. Virology 235: 179-190, 1997
16. Segerer S, Mack M, Regele H, Kerjaschki D, Schlondorff D: Expression of the C-C chemokine receptor 5 in human kidney diseases. Kidney Int 56: 52-64, 1999
17. Eitner F, Cui Y, Hudkins KL, Anderson DM, Schmidt A, Morton WR, Alpers CE: Chemokine receptor (CCR5) expression in human kidneys pnd in the HIV infected macaque. Kidney Int 54: 1945-1954, 1998
18. Eitner F, Cui Y, Hudkins KL, Alpers CE: Chemokine receptor (CXCR4) mRNA expressing leukocytes are increased in human renal allograft rejection. Transplantation 66: 1551-1557, 1998
19. Rollins BJ: Chemokines. Blood 90: 909-928, 1997
20. Luster AD: Chemokines: Chemotactic cytokines that mediate inflammation. N Engl J Med 338: 436-445, 1998
21. Langs C, Gallo GR, Schacht RG, Sidhu G, Baldwin DS: Rapid renal failure in AIDS-associated focal glomerulosclerosis. Arch Intern Med 150: 287-292, 1990
22. Kimmel PL, Ferreira-Centeno A, Farkas-Szallasi T, Abraham AA, Garrett CT: Viral DNA in microdissected renal biopsy tissue from HIV infected patients with nephrotic syndrome. Kidney Int 43: 1347-1352, 1993
23. Bodi I, Abraham AA, Kimmel PL: Apoptosis in human immunodeficiency virus-associated nephropathy. Am J Kidney Dis 26: 286-291, 1995
24. Cantor ES, Kimmel PL, Bosch JP: Effect of race on expression of acquired immunodeficiency syndrome-associated nephropathy. Arch Intern Med 151: 125-128, 1991
25. Coombs RW, Collier AC, Allain JP, Nikora B, Leuther M, Gjerset GF, Corey L: Plasma viremia in human immunodeficiency virus infection. N Engl J Med 321: 1626-1631, 1989
26. Peden K, Emerman M, Montagnier L: Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI. Virology 185: 661-672, 1991
27. Kaluza G, Willems WR, Lohmeyer J, Altmannsberger M, Bohle RM, Lubke S: A monoclonal antibody that recognizes a formalin-resistant epitope on the p 24 core protein of HIV-1. Pathol Res Pract 188: 91-96, 1992
28. Daugharty H, Long EG, Swisher BL, Warfield DT, Feorino PM: Comparative study with in situ hybridization and immunocytochemistry in detection of HIV-1 in formalin-fixed paraffin-embedded cell cultures. J Clin Lab Anal 4: 283-288, 1990
29. Alpers CE, Davis CL, Barr D, Marsh CL, Hudkins KL: Identification of platelet-derived growth factor A and B chains in human renal vascular rejection. Am J Pathol 148: 439-451, 1996
30. Fox CH, Tenner-Racz K, Racz P, Firpo A, Pizzo PA, Fauci AS: Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA. J Infect Dis 164: 1051-1057, 1991
31. Burke AP, Benson W, Ribas JL, Anderson D, Chu WS, Smialek J, Virmani R: Postmortem localization of HIV-1 RNA by in situ hybridization in lymphoid tissues of intravenous drug addicts who died unexpectedly. Am J Pathol 142: 1701-1713, 1993
32. Pantaleo G, Graziosi C, Demarest JF, Butini L, Montroni M, Fox CH, Orenstein JM, Kotler DP, Fauci AS: HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 362: 355-358, 1993
33. Embretson J, Zupancic M, Ribas JL, Burke A, Racz P, Tenner-Racz K, Haase AT: Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362: 359-362, 1993
34. Tenner-Racz K, Stellbrink HJ, van Lunzen J, Schneider C, Jacobs JP, Raschdorff B, Grosschupff G, Steinman RM, Racz P: The unenlarged lymph nodes of HIV-1-infected, asymptomatic patients with high CD4 T cell counts are sites for virus replication and CD4 T cell proliferation: The impact of highly active antiretroviral therapy. J Exp Med 187: 949-959, 1998
35. Pantaleo G, Cohen OJ, Schacker T, Vaccarezza M, Graziosi C, Rizzardi GP, Kahn J, Fox CH, Schnittman SM, Schwartz DH, Corey L, Fauci AS: Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: Implications for antiviral therapy. Nat Med 4: 341-345, 1998
36. Nadasdy T, Hanson-Painton O, Davis LD, Miller KW, DeBault LE, Burns DK, Silva FG: Conditions affecting the immunohistochemical detection of HIV in fixed and embedded renal and nonrenal tissues. Mod Pathol 5: 283-291, 1992
37. Yamamoto T, Noble NA, Miller DE, Gold LI, Hishida A, Nagase M, Cohen AH, Border WA: Increased levels of transforming growth factor-beta in HIV-associated nephropathy. Kidney Int 55: 579-592, 1999
38. Baggiolini M, Dewald B, Moser B: Human chemokines: An update. Annu Rev Immunol 15: 675-705, 1997
39. Endres MJ, Clapham PR, Marsh M, Ahuja M, Turner JD, McKnight A, Thomas JF, Stoebenau-Haggarty B, Choe S, Vance PJ, Wells TN, Power CA, Sutterwala SS, Doms RW, Landau NR, Hoxie JA: CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. Cell 87: 745-756, 1996
40. Edinger AL, Mankowski JL, Doranz BJ, Margulies BJ, Lee B, Rucker J, Sharron M, Hoffman TL, Berson JF, Zink MC, Hirsch VM, Clements JE, Doms RW: CD4-independent. CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. Proc Natl Acad Sci USA 94: 14742-14747, 1997
41. Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L, He T, Kang S, Ceradini D, Jin Z, Yazdanbakhsh K, Kunstman K, Erickson D, Dragon E, Landau NR, Phair J, Ho DD, Koup RA: The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 2: 1240-1243, 1996
42. Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, Goedert JJ, Buchbinder SP, Vittinghoff E, Gomperts E, Donfield S, Vlahov D, Kaslow R, Saah A, Rinaldo C, Detels R, O'Brien SJ: Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science 273: 1856-1862, 1996
43. Walli R, Reinhart B, Luckow B, Lederer E, Loch O, Malo A, Wank R, Schlondorff D, Goebel FD: HIV-1-infected long-term slow progressors heterozygous for delta32-CCR5 show significantly lower plasma viral load than wild-type slow progressors. J Acquir Immune Defic Syndr Hum Retrovirol 18: 229-233, 1998
44. Winkler C, Modi W, Smith MW, Nelson GW, Wu X, Carrington M, Dean M, Honjo T, Tashiro K, Yabe D, Buchbinder S, Vittinghoff E, Goedert JJ, O'Brien TR, Jacobson LP, Detels R, Donfield S, Willoughby A, Gomperts E, Vlahov D, Phair J, O'Brien SJ: Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC). Science 279: 389-393, 1998
45. Raport CJ, Gosling J, Schweickart VL, Gray PW, Charo IF: Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha. J Biol Chem 271: 17161-17166, 1996
46. Rottman JB, Ganley KP, Williams K, Wu L, Mackay CR, Ringler DJ: Cellular localization of the chemokine receptor CCR5: Correlation to cellular targets of HIV-1 infection. Am J Pathol 151: 1341-1351, 1997
47. Loetscher M, Geiser T, O'Reilly T, Zwahlen R, Baggiolini M, Moser B: Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem 269: 232-237, 1994
48. Federsppiel B, Melhado IG, Duncan AM, Delaney A, Schappert K, Clark-Lewis I, Jirik FR: Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seventransmembrane segment (7-TMS) receptor isolated from human spleen. Genomics 16: 707-712, 1993
49. Alpers CE, McClure J, Bursten SL: Human mesangial cells are resistant to productive infection by multiple strains of human immunodeficiency virus types 1 and 2. Am J Kidney Dis 19: 126-130, 1992
50. Karlsson-Parra A, Dimeny E, Fellstrom B, Klareskog L: HIV receptors (CD4 antigen) in normal human glomerular cells [Letter]. N Engl J Med 320: 741, 1989
51. Cohen AH, Sun NC, Shapshak P, Imagawa DT: Demonstration of human immunodeficiency virus in renal epithelium in HIV-associated nephropathy. Mod Pathol 2: 125-128, 1989
52. Barbiano di Belgiojoso G, Genderini A, Vago L, Parravicini C, Bertoli S, Landriani N: Absence of HIV antigens in renal tissue from patients with HIV-associated nephropathy. Nephrol Dial Transplant 5: 489-492, 1990
53. Pardo V, Shapshak P, Yoshioka M, Strauss J: HIV associated nephropathy (HIVAN): Direct renal invasion or indirect glomerular involvement? [Abstract] FASEB J 5: A907, 1991
54. Strappe PM, Wang TH, McKenzie CA, Lowrie S, Simmonds P, Bell JE: Enhancement of immunohistochemical detection of HIV-1 p24 antigen in brain by tyramide signal amplification. J Virol Methods 67: 103-112, 1997