메뉴 건너뛰기




Volumn 15, Issue 2, 2000, Pages 79-89

Addiction and its reward process through polymorphisms of the D2 dopamine receptor gene: A review

Author keywords

Alcoholism; Dopamine; DRD2 gene; Drugs; Nicotine; Obesity

Indexed keywords

ALCOHOL; CARBON 11; DOPAMINE 2 RECEPTOR; FLUORODEOXYGLUCOSE F 18; IODINE 123; IODINE 125; NICOTINE; RACLOPRIDE; TRITIUM;

EID: 0034072399     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-9338(00)00208-X     Document Type: Article
Times cited : (249)

References (73)
  • 1
    • 0027153561 scopus 로고
    • Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients.
    • Adams K.M., Gilman S., Koeppe R.A., Kluin K.J., Brunberg J.A., Dede D., et al. Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients. Alcohol Clin Exp Res. 17:1993;205-210.
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 205-210
    • Adams, K.M.1    Gilman, S.2    Koeppe, R.A.3    Kluin, K.J.4    Brunberg, J.A.5    Dede, D.6
  • 3
    • 0026719298 scopus 로고
    • Types of alcoholics: I. Evidence for an empirically derived typology based on indicators of vulnerability and severity.
    • Babor T.F., Hofmann M., DelBoca F.K., Hesselbrock V., Meyer R.E., Dolinsky Z.S., et al. Types of alcoholics: I. Evidence for an empirically derived typology based on indicators of vulnerability and severity. Arch Gen Psychiatry. 49:1992;599-608.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 599-608
    • Babor, T.F.1    Hofmann, M.2    Delboca, F.K.3    Hesselbrock, V.4    Meyer, R.E.5    Dolinsky, Z.S.6
  • 4
    • 0030033685 scopus 로고    scopus 로고
    • Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking.
    • Benjamin J., Li L., Patterson C., Greenberg B.D., Murphy D.L., Hamer D.H. Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nat Genet. 12:1996;81-84.
    • (1996) Nat Genet , vol.12 , pp. 81-84
    • Benjamin, J.1    Li, L.2    Patterson, C.3    Greenberg, B.D.4    Murphy, D.L.5    Hamer, D.H.6
  • 5
    • 0028912453 scopus 로고
    • Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele.
    • Berman S.M., Noble E.P. Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele. Behav Genet. 25:1995;45-58.
    • (1995) Behav Genet , vol.25 , pp. 45-58
    • Berman, S.M.1    Noble, E.P.2
  • 6
    • 0030609829 scopus 로고    scopus 로고
    • The D2 dopamine receptor (DRD2) gene and family stress. Interactive effects on cognitive functioning in children.
    • Berman S.M., Noble E.P. The D2 dopamine receptor (DRD2) gene and family stress. Interactive effects on cognitive functioning in children. Behav Genet. 27:1997;33-43.
    • (1997) Behav Genet , vol.27 , pp. 33-43
    • Berman, S.M.1    Noble, E.P.2
  • 7
    • 0028588066 scopus 로고
    • Prolonged P300 latency in a neuropsychiatric population with the D2 dopamine receptor A1 allele.
    • Blum K., Braverman E.P., Dinardo M.J., Wood R.C., Sheridan P.J. Prolonged P300 latency in a neuropsychiatric population with the D2 dopamine receptor A1 allele. Pharmacogenetics. 3:1994;313-322.
    • (1994) Pharmacogenetics , vol.3 , pp. 313-322
    • Blum, K.1    Braverman, E.P.2    Dinardo, M.J.3    Wood, R.C.4    Sheridan, P.J.5
  • 8
    • 0026002032 scopus 로고
    • Association of the A1 allele of the human D2 dopamine receptor gene with severe alcoholism.
    • Blum K., Noble E.P., Sheridan P.J., Finley O., Montgomery A., Ritchie T., et al. Association of the A1 allele of the human D2 dopamine receptor gene with severe alcoholism. Alcohol. 8:1991;409-416.
    • (1991) Alcohol , vol.8 , pp. 409-416
    • Blum, K.1    Noble, E.P.2    Sheridan, P.J.3    Finley, O.4    Montgomery, A.5    Ritchie, T.6
  • 10
    • 0029006018 scopus 로고
    • Dopamine D2 receptor gene variants: Association and linkage studies in impulsive-addictive-compulsive behavior.
    • Blum K., Sheridan P.J., Wood R.C., Braverman E.R., Chen I.J.H., Comings D.E. Dopamine D2 receptor gene variants: Association and linkage studies in impulsive-addictive-compulsive behavior. Pharmacogenetics. 5:1995;121-141.
    • (1995) Pharmacogenetics , vol.5 , pp. 121-141
    • Blum, K.1    Sheridan, P.J.2    Wood, R.C.3    Braverman, E.R.4    Chen, I.J.H.5    Comings, D.E.6
  • 11
    • 0025663664 scopus 로고
    • Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.
    • Bolos A.M., Dean M., Lucase-Derse S., Ramsburg M., Brown G.L., Goldman D., et al. Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism. JAMA. 264:1990;3156-3160.
    • (1990) JAMA , vol.264 , pp. 3156-3160
    • Bolos, A.M.1    Dean, M.2    Lucase-Derse, S.3    Ramsburg, M.4    Brown, G.L.5    Goldman, D.6
  • 12
    • 0023257348 scopus 로고
    • Neurogenetic adaptive mechanisms in alcoholism.
    • Cloninger C.R. Neurogenetic adaptive mechanisms in alcoholism. Science. 236:1987;410-416.
    • (1987) Science , vol.236 , pp. 410-416
    • Cloninger, C.R.1
  • 13
    • 0025925208 scopus 로고
    • D2 dopamine receptor gene is associated but not linked with alcoholism.
    • Cloninger C.R. D2 dopamine receptor gene is associated but not linked with alcoholism. JAMA. 266:1991;1833-1834.
    • (1991) JAMA , vol.266 , pp. 1833-1834
    • Cloninger, C.R.1
  • 14
    • 0025925207 scopus 로고
    • The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders.
    • Comings D.E., Comings B.G., Muhleman D., Dietz G., Shahbahrami B., Tast D., et al. The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders. JAMA. 266:1991;1793-1800.
    • (1991) JAMA , vol.266 , pp. 1793-1800
    • Comings, D.E.1    Comings, B.G.2    Muhleman, D.3    Dietz, G.4    Shahbahrami, B.5    Tast, D.6
  • 17
    • 0030229897 scopus 로고    scopus 로고
    • Genetic variants of the human obesity (OB) gene: Association with body mass index in young women, psychiatric symptoms, and interaction with the dopamine D2 receptor (DRD2) gene.
    • Comings D.E., Gade R., Macmurray J.P., Muhleman D., Peters W.R. Genetic variants of the human obesity (OB) gene: association with body mass index in young women, psychiatric symptoms, and interaction with the dopamine D2 receptor (DRD2) gene. Mol Psychiatry. 1:1996;325-335.
    • (1996) Mol Psychiatry , vol.1 , pp. 325-335
    • Comings, D.E.1    Gade, R.2    MacMurray, J.P.3    Muhleman, D.4    Peters, W.R.5
  • 20
    • 0028307802 scopus 로고
    • The D2 dopamine receptor gene and alcoholism: A genetic effect on the liability for alcoholism.
    • Cook C.C.H., Gurling H.M.D. The D2 dopamine receptor gene and alcoholism: A genetic effect on the liability for alcoholism. J R Soc M. 87:1994;400-402.
    • (1994) J R Soc M , vol.87 , pp. 400-402
    • Cook, C.C.H.1    Gurling, H.M.D.2
  • 21
    • 13344275183 scopus 로고    scopus 로고
    • Dopamine D4 receptor (DRD4) exon III polymorphism associated with the human personality trait of novelty seeking.
    • Ebstein R.P., Novick O., Umansky R., Priel B., Osher Y., Blaine D., et al. Dopamine D4 receptor (DRD4) exon III polymorphism associated with the human personality trait of novelty seeking. Nat Genet. 12:1996;78-80.
    • (1996) Nat Genet , vol.12 , pp. 78-80
    • Ebstein, R.P.1    Novick, O.2    Umansky, R.3    Priel, B.4    Osher, Y.5    Blaine, D.6
  • 22
    • 0042708521 scopus 로고    scopus 로고
    • D2 dopamine receptor Taq1 A genotypic differences in event-related brain potentials.
    • Harris L.S. Rockville MD, NIH, National Institute of Drug Abuse
    • Gabbay F.H., Duncan C.C., Bird G., Uhl G.R., Mirsky A.F. D2 dopamine receptor Taq1 A genotypic differences in event-related brain potentials. Harris L.S. Problems of Drug Dependence. NIDA Research Monograph 162. 129:1996;Rockville MD, NIH, National Institute of Drug Abuse.
    • (1996) Problems of Drug Dependence. NIDA Research Monograph 162. , vol.129
    • Gabbay, F.H.1    Duncan, C.C.2    Bird, G.3    Uhl, G.R.4    Mirsky, A.F.5
  • 23
    • 0031970016 scopus 로고    scopus 로고
    • Common quantitative trait loci for alcohol-related behaviors and CNS neurotensin measures: Voluntary ethanol consumption.
    • Gehle V.M., Erwin V.G. Common quantitative trait loci for alcohol-related behaviors and CNS neurotensin measures: voluntary ethanol consumption. Alcohol Clin Exp Res. 22:1998;40-48.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 40-48
    • Gehle, V.M.1    Erwin, V.G.2
  • 25
    • 0027339609 scopus 로고
    • The A1 allele of the D2 dopamine receptor gene and alcoholism.
    • Gelernter J., Goldman D., Risch N. The A1 allele of the D2 dopamine receptor gene and alcoholism. JAMA. 269:1993;1673-1677.
    • (1993) JAMA , vol.269 , pp. 1673-1677
    • Gelernter, J.1    Goldman, D.2    Risch, N.3
  • 26
    • 0025925209 scopus 로고
    • No association between an allele of the D2 dopamine receptor gene (DRD2) and alcoholism.
    • Gelernter J., O'Malley S., Risch N., Kranzler H.R., Krystal J., Merikangas K., et al. No association between an allele of the D2 dopamine receptor gene (DRD2) and alcoholism. JAMA. 266:1991;1801-1807.
    • (1991) JAMA , vol.266 , pp. 1801-1807
    • Gelernter, J.1    O'Malley, S.2    Risch, N.3    Kranzler, H.R.4    Krystal, J.5    Merikangas, K.6
  • 27
    • 0026615089 scopus 로고
    • D2 dopamine receptor genotype and cerebral spinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States.
    • Goldman D., Dean M., Brown G.L., Bolos A.N., Tokola R., Virkkunen M., et al. D2 dopamine receptor genotype and cerebral spinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States. Acta Psychiatr Scand. 86:1992;351-357.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 351-357
    • Goldman, D.1    Dean, M.2    Brown, G.L.3    Bolos, A.N.4    Tokola, R.5    Virkkunen, M.6
  • 28
    • 0028299122 scopus 로고
    • Are genes coding for dopamine receptors implicated in alcoholism?
    • Gorwood P., Ades J., Feingold J. Are genes coding for dopamine receptors implicated in alcoholism? Eur Psychiatry. 9:1994;63-69.
    • (1994) Eur Psychiatry , vol.9 , pp. 63-69
    • Gorwood, P.1    Ades, J.2    Feingold, J.3
  • 29
    • 0024474112 scopus 로고
    • The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a Taq1 RFLP.
    • Grandy D.K., Litt M., Allen L., Bunzow J.R., Marchionni M., Makam H., et al. The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a Taq1 RFLP. Am J Hum Genet. 45:1989;778-785.
    • (1989) Am J Hum Genet , vol.45 , pp. 778-785
    • Grandy, D.K.1    Litt, M.2    Allen, L.3    Bunzow, J.R.4    Marchionni, M.5    Makam, H.6
  • 30
    • 10144262631 scopus 로고    scopus 로고
    • Lack of allelic association of dopamine D1 and D2 (TaqI A) receptor gene polymorphisms with reduced dopaminergic sensitivity in alcoholism.
    • Heinz A., Sander T., Harms H., Finckh U., Kuhn S., Dufeu P., et al. Lack of allelic association of dopamine D1 and D2 (TaqI A) receptor gene polymorphisms with reduced dopaminergic sensitivity in alcoholism. Alcohol Clin Exp Res. 20:1996;1109-1113.
    • (1996) Alcohol Clin Exp Res , vol.20 , pp. 1109-1113
    • Heinz, A.1    Sander, T.2    Harms, H.3    Finckh, U.4    Kuhn, S.5    Dufeu, P.6
  • 32
    • 0031964436 scopus 로고    scopus 로고
    • Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high-risk for alcoholism.
    • Hill S.Y., Locke J., Zezza N., Kaplan B., Neiswanger K., Steinhauer S.R., et al. Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high-risk for alcoholism. Biol Psychiatry. 43:1998;40-51.
    • (1998) Biol Psychiatry , vol.43 , pp. 40-51
    • Hill, S.Y.1    Locke, J.2    Zezza, N.3    Kaplan, B.4    Neiswanger, K.5    Steinhauer, S.R.6
  • 33
    • 0031596425 scopus 로고    scopus 로고
    • The regulation of D2 dopamine receptor expression.
    • Hitzemann R.J. The regulation of D2 dopamine receptor expression. Mol Psychiatry. 3:1998;198-203.
    • (1998) Mol Psychiatry , vol.3 , pp. 198-203
    • Hitzemann, R.J.1
  • 34
    • 1842332176 scopus 로고    scopus 로고
    • Lack of evidence for allelic association between personality traits and dopamine D4 receptor gene polymorphism.
    • Jönsson E.G., Nöthen M.M., Gustavsson J.P., Neidt H., Brené S., Tylee A., et al. Lack of evidence for allelic association between personality traits and dopamine D4 receptor gene polymorphism. Am J Psychiatry. 154:1997;697-699.
    • (1997) Am J Psychiatry , vol.154 , pp. 697-699
    • Jönsson, E.G.1    Nöthen, M.M.2    Gustavsson, J.P.3    Neidt, H.4    Brené, S.5    Tylee, A.6
  • 35
    • 0026507628 scopus 로고
    • Drugs of abuse. Anatomy, pharmacology and function of reward pathways.
    • Koob G.R. Drugs of abuse. Anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci. 13:1992;177-184.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 177-184
    • Koob, G.R.1
  • 36
    • 0031596430 scopus 로고    scopus 로고
    • D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene.
    • Laruelle M., Gelernter J., Innis R.B. D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene. Mol Psychiatry. 3:1998;261-265.
    • (1998) Mol Psychiatry , vol.3 , pp. 261-265
    • Laruelle, M.1    Gelernter, J.2    Innis, R.B.3
  • 37
    • 0031568339 scopus 로고    scopus 로고
    • Association of the D2 dopamine receptor A1 allele with alcoholism: Medical severity of alcoholism and type of controls.
    • Lawford B.R., Young R.M., Rowell J.A., Gibson J.N., Feeney G.F.X., Ritchie T.L., et al. Association of the D2 dopamine receptor A1 allele with alcoholism: Medical severity of alcoholism and type of controls. Biol Psychiatry. 41:1997;386-393.
    • (1997) Biol Psychiatry , vol.41 , pp. 386-393
    • Lawford, B.R.1    Young, R.M.2    Rowell, J.A.3    Gibson, J.N.4    Feeney, G.F.X.5    Ritchie, T.L.6
  • 38
  • 40
    • 0030275937 scopus 로고    scopus 로고
    • The association between the dopamine D4 receptor (DRD4) 16 amino acid repeat polymorphism and novelty seeking.
    • Malhotra A.K., Virkunnen M., Rooney W., Eggert M., Linnoila M., Goldman D. The association between the dopamine D4 receptor (DRD4) 16 amino acid repeat polymorphism and novelty seeking. Mol Psychiatry. 1:1996;388-391.
    • (1996) Mol Psychiatry , vol.1 , pp. 388-391
    • Malhotra, A.K.1    Virkunnen, M.2    Rooney, W.3    Eggert, M.4    Linnoila, M.5    Goldman, D.6
  • 41
    • 0029147189 scopus 로고
    • Association and linkage studies of the TaqI A allele of the dopamine D2 receptor gene in samples of female and male alcoholics.
    • Neiswanger K., Hill S.Y., Kaplan B.B. Association and linkage studies of the TaqI A allele of the dopamine D2 receptor gene in samples of female and male alcoholics. Am J Med Genet. 60:1995;267-271.
    • (1995) Am J Med Genet , vol.60 , pp. 267-271
    • Neiswanger, K.1    Hill, S.Y.2    Kaplan, B.B.3
  • 42
    • 0000890444 scopus 로고    scopus 로고
    • Alcoholism and the dopaminergic system: A review.
    • Noble E.P. Alcoholism and the dopaminergic system: A review. Addict Biol. 1:1996;333-348.
    • (1996) Addict Biol , vol.1 , pp. 333-348
    • Noble, E.P.1
  • 43
    • 0031595664 scopus 로고    scopus 로고
    • The D2 dopamine receptor gene: A review of association studies in alcoholism and phenotypes.
    • Noble E.P. The D2 dopamine receptor gene: A review of association studies in alcoholism and phenotypes. Alcohol. 16:1998;33-45.
    • (1998) Alcohol , vol.16 , pp. 33-45
    • Noble, E.P.1
  • 44
    • 0032481648 scopus 로고    scopus 로고
    • The DRD2 gene, smoking, and lung cancer.
    • Noble E.P. The DRD2 gene, smoking, and lung cancer. J Natl Cancer Inst. 90:1998;343-345.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 343-345
    • Noble, E.P.1
  • 45
    • 0028279022 scopus 로고
    • Prolonged P300 latency in children with the D2 dopamine receptor A1 allele.
    • Noble E.P., Berman S.M., Ozkaragoz T.Z., Ritchie T. Prolonged P300 latency in children with the D2 dopamine receptor A1 allele. Am J Hum Genet. 54:1994;658-668.
    • (1994) Am J Hum Genet , vol.54 , pp. 658-668
    • Noble, E.P.1    Berman, S.M.2    Ozkaragoz, T.Z.3    Ritchie, T.4
  • 46
    • 0027340744 scopus 로고
    • Alcoholism and the D2 receptor gene [letter].
    • Noble E.P., Blum K. Alcoholism and the D2 receptor gene [letter]. JAMA. 270:1993;1547.
    • (1993) JAMA , vol.270 , pp. 1547
    • Noble, E.P.1    Blum, K.2
  • 48
    • 0025923342 scopus 로고
    • Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism.
    • Noble E.P., Blum K., Ritchie T., Montgomery A., Sheridan P.J. Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry. 48:1991;648-654.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 648-654
    • Noble, E.P.1    Blum, K.2    Ritchie, T.3    Montgomery, A.4    Sheridan, P.J.5
  • 49
    • 0010957531 scopus 로고    scopus 로고
    • The D2 dopamine receptor gene: Obesity, smoking and mood.
    • S.T. St. Jeor. Chapman and Hall; New York
    • Noble E.P., Fitch R.J., Ritchie T., Brunner R.L., Zhang X., Stjeor S.C., et al. The D2 dopamine receptor gene: obesity, smoking and mood. St. Jeor S.T. Obesity Assessment. 1997;522-533 Chapman and Hall; New York.
    • (1997) Obesity Assessment. , pp. 522-533
    • Noble, E.P.1    Fitch, R.J.2    Ritchie, T.3    Brunner, R.L.4    Zhang, X.5    Stjeor, S.C.6
  • 51
    • 0000661803 scopus 로고    scopus 로고
    • The D2 dopamine receptor (DRD2) gene and methadone treatment outcome of opioid-dependent patients.
    • Noble E.P., Lawford B.R., Ritchie T., Young R.M., Zhang X. The D2 dopamine receptor (DRD2) gene and methadone treatment outcome of opioid-dependent patients. Abstr Soc. Neurosci. 24:1998;770.
    • (1998) Abstr Soc. Neurosci , vol.24 , pp. 770
    • Noble, E.P.1    Lawford, B.R.2    Ritchie, T.3    Young, R.M.4    Zhang, X.5
  • 56
    • 0027176835 scopus 로고
    • Dopamine D2 receptor RFLPs, haplotypes and their association with substance use in black and Caucasian research volunteers.
    • O'Hara B.F., Smith S.S., Bird G., Persico A.M., Suarez B.K., Cutting G.R., et al. Dopamine D2 receptor RFLPs, haplotypes and their association with substance use in black and Caucasian research volunteers. Hum Her. 43:1993;209-218.
    • (1993) Hum Her , vol.43 , pp. 209-218
    • O'Hara, B.F.1    Smith, S.S.2    Bird, G.3    Persico, A.M.4    Suarez, B.K.5    Cutting, G.R.6
  • 57
    • 0025812839 scopus 로고
    • Alcoholism and alleles of the human D2 receptor locus: Studies of association and linkage.
    • Parsian A., Todd R.D., Devor E.J., O'Malley K.L., Suarez B.K., Reich T., et al. Alcoholism and alleles of the human D2 receptor locus: Studies of association and linkage. Arch Gen Psychiatry. 48:1991;655-663.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 655-663
    • Parsian, A.1    Todd, R.D.2    Devor, E.J.3    O'Malley, K.L.4    Suarez, B.K.5    Reich, T.6
  • 58
    • 0027320815 scopus 로고
    • Review of the putative association of dopamine D2 receptor and alcoholism: A meta-analysis.
    • Pato C.N., Macciardi F., Pato M.T., Verga M., Kennedy H. Review of the putative association of dopamine D2 receptor and alcoholism: A meta-analysis. Am J Med Genet. 48:1993;78-82.
    • (1993) Am J Med Genet , vol.48 , pp. 78-82
    • Pato, C.N.1    MacCiardi, F.2    Pato, M.T.3    Verga, M.4    Kennedy, H.5
  • 59
    • 0030587624 scopus 로고    scopus 로고
    • D2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphism: Enhanced frequencies in psychostimulant-preferring polysubstance abusers.
    • Persico A.M., Bird G., Gabbay F.H., Uhl G.R. D2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphism: Enhanced frequencies in psychostimulant-preferring polysubstance abusers. Biol Psychiatry. 40:1996;776-784.
    • (1996) Biol Psychiatry , vol.40 , pp. 776-784
    • Persico, A.M.1    Bird, G.2    Gabbay, F.H.3    Uhl, G.R.4
  • 62
    • 0028937958 scopus 로고
    • Effects of acute and repeated ethanol exposures on the locomotor activity of RXD recombinant inbred mice.
    • Phillips T.J., Huson M., Gwazdon C., Burkhart-Kasch S., Shen E.H. Effects of acute and repeated ethanol exposures on the locomotor activity of RXD recombinant inbred mice. Alcohol Clin Exp Res. 19:1995;269-278.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 269-278
    • Phillips, T.J.1    Huson, M.2    Gwazdon, C.3    Burkhart-Kasch, S.4    Shen, E.H.5
  • 63
    • 0031752522 scopus 로고    scopus 로고
    • The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers.
    • Pohjalainen T., Rinne J.O., Någren K., Lehikoinen P., Anttila K., Syvälahti E.K.G., et al. The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry. 3:1998;256-260.
    • (1998) Mol Psychiatry , vol.3 , pp. 256-260
    • Pohjalainen, T.1    Rinne, J.O.2    Någren, K.3    Lehikoinen, P.4    Anttila, K.5    Syvälahti, E.K.G.6
  • 64
    • 0026670871 scopus 로고
    • Genetic vulnerability in drug abuse: The dopamine D2 receptor TaqI B RFLP is more frequent in polysubstance abusers.
    • Smith S.S., O'Hara B.F., Persico A.M., Gorelick D.A., Newlin D.B., Vlahov D., et al. Genetic vulnerability in drug abuse: The dopamine D2 receptor TaqI B RFLP is more frequent in polysubstance abusers. Arch Gen Psychiatry. 49:1992;723-727.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 723-727
    • Smith, S.S.1    O'Hara, B.F.2    Persico, A.M.3    Gorelick, D.A.4    Newlin, D.B.5    Vlahov, D.6
  • 65
    • 0032481666 scopus 로고    scopus 로고
    • Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.
    • Spitz M.R., Shi H., Yang F., Hudmon K.S., Jiang H., Chamberlain R.M., et al. Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients. J Natl Cancer Inst. 90:1998;358-363.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 358-363
    • Spitz, M.R.1    Shi, H.2    Yang, F.3    Hudmon, K.S.4    Jiang, H.5    Chamberlain, R.M.6
  • 66
    • 0028182014 scopus 로고
    • Linkage disequilibria and the D2 dopamine receptor locus (DRD2) in alcoholics and controls.
    • Suarez B.K., Parsian A., Hampe C.L., Todd R.D., Reich T., Cloninger C.R. Linkage disequilibria and the D2 dopamine receptor locus (DRD2) in alcoholics and controls. Genomics. 19:1994;12-20.
    • (1994) Genomics , vol.19 , pp. 12-20
    • Suarez, B.K.1    Parsian, A.2    Hampe, C.L.3    Todd, R.D.4    Reich, T.5    Cloninger, C.R.6
  • 68
    • 9844233161 scopus 로고    scopus 로고
    • D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: Reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele.
    • Thompson J., Thomas N., Singleton A., Piggott M., Lloyd S., Perry C.M., et al. D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics. 7:1997;479-484.
    • (1997) Pharmacogenetics , vol.7 , pp. 479-484
    • Thompson, J.1    Thomas, N.2    Singleton, A.3    Piggott, M.4    Lloyd, S.5    Perry, C.M.6
  • 69
    • 0027450927 scopus 로고
    • Substance abuse vulnerability and D2 receptor gene.
    • Uhl G., Blum K., Noble E., Smith S. Substance abuse vulnerability and D2 receptor gene. Trends Neurosci. 16:1993;83-88.
    • (1993) Trends Neurosci , vol.16 , pp. 83-88
    • Uhl, G.1    Blum, K.2    Noble, E.3    Smith, S.4
  • 70
    • 0027336093 scopus 로고
    • Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers.
    • Volkow N.D., Fowler J.B., Wang G.J., Hitzemann R., Logan J., Schyler D.J., et al. Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse. 14:1993;169-177.
    • (1993) Synapse , vol.14 , pp. 169-177
    • Volkow, N.D.1    Fowler, J.B.2    Wang, G.J.3    Hitzemann, R.4    Logan, J.5    Schyler, D.J.6
  • 72
    • 0023687614 scopus 로고
    • PET determination of regional cerebral glucose metabolism in alcohol-dependent men and healthy controls using 11C-glucose.
    • Wik G., Borg S., Sjögren I., Wiesel F.A., Bloomquist G., Borg J., et al. PET determination of regional cerebral glucose metabolism in alcohol-dependent men and healthy controls using 11C-glucose. Acta Psychiatr Scand. 78:1988;234-241.
    • (1988) Acta Psychiatr Scand , vol.78 , pp. 234-241
    • Wik, G.1    Borg, S.2    Sjögren, I.3    Wiesel, F.A.4    Bloomquist, G.5    Borg, J.6
  • 73


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.