Association of the D2 dopamine receptor A1 allele with alcoholism: Medical severity of alcoholism and type of controls

Biological Psychiatry

Volumn 41, Issue 4, 1997, Pages 386-393

  Lawford, Bruce R ^a   Young, Ross McD ^a   Rowell, John A ^b   Gibson, John N ^c   Feeney, G F X ^d   Ritchie, Terry L ^e   Syndulko, Karl ^f   Noble, Ernest P ^e  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^c GREENSLOPES PRIVATE HOSPITAL   (Australia)

^d PRINCESS ALEXANDRA HOSPITAL   (Australia)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

A1 allele; Alcoholism; Control types; D2 dopamine receptor gene; Medical severity

Indexed keywords

DOPAMINE RECEPTOR; DOPAMINE 2 RECEPTOR;

ADULT; ALCOHOLISM; ALLELE; ARTICLE; CONTROL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; COMPARATIVE STUDY; DRINKING BEHAVIOR; GENETICS; GENOTYPE; HOSPITALIZATION;

ALCOHOL DRINKING; ALCOHOLISM; ALLELES; FEMALE; GENOTYPE; HUMANS; MALE; RECEPTORS, DOPAMINE D2; SEVERITY OF ILLNESS INDEX;

EID: 0031568339     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(96)00478-7     Document Type: Article

References (42)

1. 2 dopamine receptor gene and alcoholism. J Psychiatr Res 27:173-179.
2. Australian National Health and Medical Research Council (1992): Is There a Safe Level of Daily Consumption of Alcohol for Men and Women? Canberra, Australia: Australian Government Publishing Service.
3. Babor TF, Hofmann M, DelBoca FK, et al (1992): Types of alcoholics: I. Evidence for an empirically derived typology based on indicators of vulnerability and severity. Arch Gen Psychiatry 49:599-608.
4. 2 dopamine receptor A1 allele. Behav Genet 25:45-58.
5. 2 receptor gene in alcoholism. JAMA 263:2055-2060.
6. 2 dopamine receptor gene with severe alcoholism. Alcohol 8:409-416.
7. 2 receptor gene variants: Association and linkage studies in impulsive-addictive-compulsive behavior. Pharmacogenetics 5:121-141.
8. 2 receptor gene and alcoholism. JAMA 264:3156-3160.
9. Cloninger CR (1987): Neurogenetic adaptive mechanisms in alcoholism. Science 236:410-416.
10. 2 dopamine receptor gene is associated but not linked with alcoholism. JAMA 266:1833-1834.
11. 2 test. Biometrics 10:417-451.
12. 2 receptor locus as a modifying gene in neuropsychiatric disorders. JAMA 266:1793-1800.
13. 2 receptor (DRD2) gene: A genetic risk factor in smoking. Am J Hum Genet 55(suppl):A182.
14. 2 receptor gene: A genetic risk factor in substance abuse. Drug Alcohol Depend 34:175-180.
15. 2 dopamine receptorgene and alcoholism: A genetic effect on the liability of alcoholism. J R Soc Med 87:400-402.
16. 2 receptor gene. Alcoholism 16:806-809.
17. 2-receptor gene polymorphisms in Scandinavian chronic alcoholics. Eur Arch Psychiatr Clin Neurosci 244:26-32.
18. 2 dopamine receptor gene (DRD2) and alcoholism. JAMA 266:1801-1807.
19. 2 dopamine receptor gene and alcoholism. JAMA 269:1673-1677.
20. Gorwood P, Ade J, Feingold J (1994): Are genes coding for dopamine receptors implicated in alcoholism? Eur Psychiatry 9:63-69.
21. Jellinek EM (1960): The Disease Concept of Alcoholism. New Haven, CT: Hill-house.
22. Koob GF (1992): Drugs of abuse: Anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 13:177-184.
23. 2 dopamine receptor A1 allele. Nature Med 1:337-341.
24. 2 receptor gene in samples of female and male alcoholics. Am J Med Genet 60:267-271.
25. Neiswanger K, Kaplan BB, Hill SY (1995b): An editorial: What can the DRD2/alcoholism story teach us about association studies in psychiatric genetics? Am J Med Genet 60:272-275.
26. 2 dopamine receptor gene: A review of association studies in alcoholism. Behav Genet 23:119-129.
27. Noble EP (1996): The gene that rewards alcoholism. Sci Med Am 3:52-61.
28. 2 dopamine receptor gene [letter]. JAMA 270:1547.
29. 2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry 48:648-654.
30. 2 dopamine receptor gene with cocaine dependence. Drug Alcohol Depend 33:271-285.
31. 2 dopamine receptor TaqI A alleles in medically ill alcoholics and nonalcoholic patients. Alcohol Alcohol 29:729-744.
32. 2 dopamine receptor gene and obesity. Int J Eat Disord 15:205-217.
33. 2 dopamine receptor gene and cigarette smoking: A reward gene? Med Hypotheses 42:257-260.
34. 2 dopamine receptor A1 allele. Am J Hum Genet 54:658-668.
35. Noble EP, Lawford BR, Syndulko K (1995): Bromocriptine in the treatment of alcoholics. Nature Med 1:720-721.
36. 2 dopamine receptor locus: Studies of association and linkage. Arch Gen Psychiatry 48:655-663.
37. Pato CN, Macciardi F, Pato MT, Verga M, Kennedy H (1993):Review of the putative association of DRD2 and alcoholism: A meta-analysis. Am J Hum Genet 48:78-82.
38. Sander T, Harms H, Podschus J, et al (1995): Dopamine D1, D2 and D3 receptor genes in alcohol dependence. Psychiat Genet 5:171-176.
39. 2 dopamine receptor TaqI B restriction fragment length polymorphism appears more frequently in polysubstance abusers. Arch Gen Psychiatry 49:723-727.
40. 2 dopamine receptor locus (DRD2) in alcoholics and controls. Genomics 19:12-20.
41. 2 dopamine receptor gene and severe alcoholism. Biol Psychiatry 31:285-290.
42. 2 receptor gene. Trends Neurosci 16:83-88.