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Volumn 16, Issue 1, 1998, Pages 33-45

The D2 dopamine receptor gene: A review of association studies in alcoholism and phenotypes

Author keywords

Alcholism; Association studies; D2 dopamine receptors; Dopamine; DRD2 gene; Drug abuse; Phenotypes; TaqI A alleles

Indexed keywords

DOPAMINE 2 RECEPTOR;

EID: 0031595664     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(97)00175-4     Document Type: Conference Paper
Times cited : (160)

References (119)
  • 1
    • 0027153561 scopus 로고
    • Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients
    • Adams K.M., Gilman S., Koeppe R.A., Kluin K.J., Brunberg J.A., Dede D., Berent S., Kroll P.D. Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients. Alcohol. Clin. Exp. Res. 17:1993;205-210.
    • (1993) Alcohol. Clin. Exp. Res. , vol.17 , pp. 205-210
    • Adams, K.M.1    Gilman, S.2    Koeppe, R.A.3    Kluin, K.J.4    Brunberg, J.A.5    Dede, D.6    Berent, S.7    Kroll, P.D.8
  • 10
    • 0030609829 scopus 로고    scopus 로고
    • 2 dopamine receptor (Drd2) gene and family stress. Interactive effects on cognitive functioning in children
    • 2 dopamine receptor (Drd2) gene and family stress. Interactive effects on cognitive functioning in children. Behav. Genet. 27:1997;33-43.
    • (1997) Behav. Genet. , vol.27 , pp. 33-43
    • Berman, S.M.1    Noble, E.P.2
  • 16
    • 0024855153 scopus 로고
    • 3H]dopamine uptake is similar in both rat striatum and nucleus accumbens
    • 3H]dopamine uptake is similar in both rat striatum and nucleus accumbens. Eur. J. Pharmacol. 173:1989;215-217.
    • (1989) Eur. J. Pharmacol. , vol.173 , pp. 215-217
    • Boja, J.W.1    Kuhar, M.J.2
  • 19
    • 0025201909 scopus 로고
    • Acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroxy-phenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat. Comparison with caudate putamen
    • Brazell M.P., Mitchell S.N., Joseph M.H., Gray J.A. Acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroxy-phenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat. Comparison with caudate putamen. Neuropsychopharmacology. 29:1990;1177-1185.
    • (1990) Neuropsychopharmacology , vol.29 , pp. 1177-1185
    • Brazell, M.P.1    Mitchell, S.N.2    Joseph, M.H.3    Gray, J.A.4
  • 20
    • 0024288262 scopus 로고
    • Evidence that the 5′-untranslated leader of mRNA affects the requirement for wheat germ initiation factors 4A, 4F, and 4G
    • Browning K.S., Lax S.R., Humphreys J., Ravel J.M., Jobling S.A., Gehrke L. Evidence that the 5′-untranslated leader of mRNA affects the requirement for wheat germ initiation factors 4A, 4F, and 4G. J. Biol. Chem. 263:1988;9630-9634.
    • (1988) J. Biol. Chem. , vol.263 , pp. 9630-9634
    • Browning, K.S.1    Lax, S.R.2    Humphreys, J.3    Ravel, J.M.4    Jobling, S.A.5    Gehrke, L.6
  • 22
    • 0024457824 scopus 로고
    • Efficiency of utilization of the simian virus 40 late polyadenylation site: Effects of upstream se-quences
    • Carswell S., Alwine J.C. Efficiency of utilization of the simian virus 40 late polyadenylation site. Effects of upstream se-quences Mol. Cell. Biol. 9:1989;4248-4258.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4248-4258
    • Carswell, S.1    Alwine, J.C.2
  • 23
    • 0023260397 scopus 로고
    • A systematic method for clinical description and classification of personality variants. A proposal
    • Cloninger C.R. A systematic method for clinical description and classification of personality variants. A proposal. Arch. Gen. Psychiatry. 44:1987;573-588.
    • (1987) Arch. Gen. Psychiatry , vol.44 , pp. 573-588
    • Cloninger, C.R.1
  • 24
    • 0023257348 scopus 로고
    • Neurogenetic adaptive mechanisms in alcoholism
    • Cloninger C.R. Neurogenetic adaptive mechanisms in alcoholism. Science. 236:1987;410-416.
    • (1987) Science , vol.236 , pp. 410-416
    • Cloninger, C.R.1
  • 25
    • 0025925208 scopus 로고
    • 2 dopamine receptor gene is associated but not linked with alcoholism
    • 2 dopamine receptor gene is associated but not linked with alcoholism. JAMA. 266:1991;1833-1834.
    • (1991) JAMA , vol.266 , pp. 1833-1834
    • Cloninger, C.R.1
  • 29
    • 0029947141 scopus 로고    scopus 로고
    • Polygenic inheritance of Tourette syndrome, stuttering, attention deficit-hyperactivity, conduct and oppositional defiant disorder: The additive and subtractive effect of the three dopaminergic genes - Drd2, DβH and DAT1
    • Comings D.E., Wu S., Chiu C., Ring R.H., Gade R., Ahn C., MacMurray J.P., Dietz G., Muhleman D. Polygenic inheritance of Tourette syndrome, stuttering, attention deficit-hyperactivity, conduct and oppositional defiant disorder. The additive and subtractive effect of the three dopaminergic genes - Drd2, DβH and DAT1 Am. J. Med. Genet. 67:1996;264-288.
    • (1996) Am. J. Med. Genet. , vol.67 , pp. 264-288
    • Comings, D.E.1    Wu, S.2    Chiu, C.3    Ring, R.H.4    Gade, R.5    Ahn, C.6    MacMurray, J.P.7    Dietz, G.8    Muhleman, D.9
  • 32
    • 0028307802 scopus 로고
    • 2 dopamine receptor gene and alcoholism: A genetic effect on the liability for alcoholism
    • 2 dopamine receptor gene and alcoholism. A genetic effect on the liability for alcoholism J. R. Soc. Med. 87:1994;400-402.
    • (1994) J. R. Soc. Med. , vol.87 , pp. 400-402
    • Cook, C.C.H.1    Gurling, H.M.D.2
  • 36
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synapatic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synapatic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. USA. 85:1988;5274-5278.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 39
    • 0026319043 scopus 로고
    • Family disruption in early life and drinking in young adulthood
    • Estaugh V., Power C. Family disruption in early life and drinking in young adulthood. Alcohol Alcohol. 26:1991;639-644.
    • (1991) Alcohol Alcohol. , vol.26 , pp. 639-644
    • Estaugh, V.1    Power, C.2
  • 41
    • 0028371763 scopus 로고
    • Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci
    • Evans L.J. Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci. Heredity. 72:1994;175-192.
    • (1994) Heredity , vol.72 , pp. 175-192
    • Evans, L.J.1
  • 42
    • 0019213960 scopus 로고
    • Differential effect of acute and chronic ethanol on dopamine metabolism in frontal cortex, caudate nucleus and substantia nigra
    • Fadda R., Argiolas A., Melis M.R., Serra G., Gessa G.I. Differential effect of acute and chronic ethanol on dopamine metabolism in frontal cortex, caudate nucleus and substantia nigra. Life Sci. 27:1980;979-986.
    • (1980) Life Sci. , vol.27 , pp. 979-986
    • Fadda, R.1    Argiolas, A.2    Melis, M.R.3    Serra, G.4    Gessa, G.I.5
  • 46
    • 0027339609 scopus 로고
    • 2 dopamine receptor gene and alcoholsim
    • 2 dopamine receptor gene and alcoholsim. JAMA. 269:1993;1673-1677.
    • (1993) JAMA , vol.269 , pp. 1673-1677
    • Gelernter, J.1    Goldman, D.2    Risch, N.3
  • 48
  • 49
    • 0026615089 scopus 로고
    • 2 dopamine receptor genotype and cerebral spinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States
    • 2 dopamine receptor genotype and cerebral spinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States. Acta Psychiatr. Scand. 86:1992;351-357.
    • (1992) Acta Psychiatr. Scand. , vol.86 , pp. 351-357
    • Goldman, D.1    Dean, M.2    Brown, G.L.3    Bolos, A.N.4    Tokola, R.5    Virkkunen, M.6    Linnoila, M.7
  • 50
    • 0028299122 scopus 로고
    • Are genes coding for dopamine receptors implicated in alcoholism?
    • Gorwood P., Ades J., Feingold J. Are genes coding for dopamine receptors implicated in alcoholism? Eur. Psychiatry. 9:1994;63-69.
    • (1994) Eur. Psychiatry , vol.9 , pp. 63-69
    • Gorwood, P.1    Ades, J.2    Feingold, J.3
  • 54
    • 0008257545 scopus 로고
    • Stress and adolescence
    • L.E. Arnold. New York: Wiley
    • Hendren R.L. Stress and adolescence. Arnold L.E. Childhood stress. 1990;247-264 Wiley, New York.
    • (1990) Childhood Stress , pp. 247-264
    • Hendren, R.L.1
  • 55
    • 0031964436 scopus 로고    scopus 로고
    • Genetic association between reduced P300 amplitude and the Drd2 dopamine receptor A1 allele in children at high-risk for alcoholism
    • Hill S.Y., Locke J., Zezza N., Kaplan B., Neiswanger K., Steinhauer S.R., Wipprecht G., Xu J. Genetic association between reduced P300 amplitude and the Drd2 dopamine receptor A1 allele in children at high-risk for alcoholism. Biol. Psychiatry. 43:1998;40-51.
    • (1998) Biol. Psychiatry , vol.43 , pp. 40-51
    • Hill, S.Y.1    Locke, J.2    Zezza, N.3    Kaplan, B.4    Neiswanger, K.5    Steinhauer, S.R.6    Wipprecht, G.7    Xu, J.8
  • 56
    • 0022899199 scopus 로고
    • Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol
    • Imperato A., Di Chiara G. Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol. J. Pharmacol. Exp. Ther. 239:1986;219-228.
    • (1986) J. Pharmacol. Exp. Ther. , vol.239 , pp. 219-228
    • Imperato, A.1    Di Chiara, G.2
  • 57
    • 0022878228 scopus 로고
    • Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats
    • Imperato A., Mulas A., Di Chiara G. Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats. Eur. J. Pharmacol. 132:1986;337-338.
    • (1986) Eur. J. Pharmacol. , vol.132 , pp. 337-338
    • Imperato, A.1    Mulas, A.2    Di Chiara, G.3
  • 58
    • 0025365391 scopus 로고
    • Comparisons of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex
    • Izenwasser S., Werling L.L., Cox B.M. Comparisons of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex. Brain Res. 520:1990;303-309.
    • (1990) Brain Res. , vol.520 , pp. 303-309
    • Izenwasser, S.1    Werling, L.L.2    Cox, B.M.3
  • 61
    • 0023724675 scopus 로고
    • Determinants that contribute to cytoplasmic stability of human c-fos and β-globin mRNAs are located at several sites in each mRNA
    • Kabnick K.S., Housman D.E. Determinants that contribute to cytoplasmic stability of human c-fos and β-globin mRNAs are located at several sites in each mRNA. Mol. Cell. Biol. 8:1988;3244-3250.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3244-3250
    • Kabnick, K.S.1    Housman, D.E.2
  • 66
    • 0026507628 scopus 로고
    • Drugs of abuse. Anatomy, pharmacology and function of reward pathways
    • Koob G.F. Drugs of abuse. Anatomy, pharmacology and function of reward pathways. Trends Pharmacol. Sci. 13:1992;177-184.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 177-184
    • Koob, G.F.1
  • 67
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander E.S., Schork N.J. Genetic dissection of complex traits. Science. 265:1994;2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 70
    • 0030275937 scopus 로고    scopus 로고
    • The association between the dopamine D4 receptor (D4dr) 16 amino acid repeat polymorphism and novelty seeking
    • Malhotra A.K., Virkunnen M., Rooney W., Eggert M., Linnoila M., Goldman D. The association between the dopamine D4 receptor (D4dr) 16 amino acid repeat polymorphism and novelty seeking. Mol. Psychiatry. 1:1996;388-391.
    • (1996) Mol. Psychiatry , vol.1 , pp. 388-391
    • Malhotra, A.K.1    Virkunnen, M.2    Rooney, W.3    Eggert, M.4    Linnoila, M.5    Goldman, D.6
  • 72
    • 0029643589 scopus 로고
    • An editorial: What can the Drd2/alcoholism story teach us about association studies in psychiatric genetics?
    • Neiswanger K., Kaplan B.B., Hill S.Y. An editorial. What can the Drd2/alcoholism story teach us about association studies in psychiatric genetics? Am. J. Med. Genet. 60:1995;272-275.
    • (1995) Am. J. Med. Genet. , vol.60 , pp. 272-275
    • Neiswanger, K.1    Kaplan, B.B.2    Hill, S.Y.3
  • 73
    • 0022773159 scopus 로고
    • Life events and substance use among adolescents: Mediating effects of perceived loss of control and meaninglessness in life
    • Newcomb M.D., Harlow L.L. Life events and substance use among adolescents. Mediating effects of perceived loss of control and meaninglessness in life J. Person. Soc. Psychol. 51:1986;564-579.
    • (1986) J. Person. Soc. Psychol. , vol.51 , pp. 564-579
    • Newcomb, M.D.1    Harlow, L.L.2
  • 74
    • 0344700608 scopus 로고
    • Genetic studies in alcoholism: CNS functioning and molecular biology
    • Noble E.P. Genetic studies in alcoholism. CNS functioning and molecular biology Psychiatr. Ann. 32:1991;215-229.
    • (1991) Psychiatr. Ann. , vol.32 , pp. 215-229
    • Noble, E.P.1
  • 75
    • 0345562792 scopus 로고
    • 2 dopamine receptor TaqI A polymorphism in hospitalized nonalcoholic and alcoholic patients
    • International Society for Biomedical Research on Alcoholism 1992 Satellite Symposium, Bordeaux, France, June 18-19; (abstr.)
    • 2 dopamine receptor TaqI A polymorphism in hospitalized nonalcoholic and alcoholic patients. In: Genetics and Alcohol-Related Diseases, International Society for Biomedical Research on Alcoholism 1992 Satellite Symposium, Bordeaux, France, June 18-19; 1992:37(abstr.).
    • (1992) In: Genetics and Alcohol-Related Diseases , pp. 37
    • Noble, E.P.1
  • 76
    • 0027571662 scopus 로고
    • 2 dopamine receptor gene: A review of association studies in alcoholism
    • 2 dopamine receptor gene. A review of association studies in alcoholism Behav. Genet. 23:1993;119-129.
    • (1993) Behav. Genet. , vol.23 , pp. 119-129
    • Noble, E.P.1
  • 77
    • 0002882852 scopus 로고    scopus 로고
    • The gene that rewards alcoholism
    • Noble E.P. The gene that rewards alcoholism. Sci. Am. Sci. Med. 3(2):1996;52-61.
    • (1996) Sci. Am. Sci. Med. , vol.3 , Issue.2 , pp. 52-61
    • Noble, E.P.1
  • 78
    • 0000890444 scopus 로고    scopus 로고
    • Alcoholism and the dopaminergic system: A review
    • Noble E.P. Alcoholism and the dopaminergic system. A review Addict. Biol. 1:1996;333-348.
    • (1996) Addict. Biol. , vol.1 , pp. 333-348
    • Noble, E.P.1
  • 79
    • 0013477206 scopus 로고    scopus 로고
    • 2 dopamine receptor gene in alcoholism, cocaine and nicotine dependence and obesity
    • K. Blum, & E.P. Noble. Boca Raton, FL: CRC Press
    • 2 dopamine receptor gene in alcoholism, cocaine and nicotine dependence and obesity. Blum K., Noble E.P. Handbook of psychiatric genetics. 1997;331-351 CRC Press, Boca Raton, FL.
    • (1997) Handbook of Psychiatric Genetics , pp. 331-351
    • Noble, E.P.1
  • 81
    • 0025772353 scopus 로고
    • 2 receptor gene and alcoholism (letter)
    • 2 receptor gene and alcoholism (letter). JAMA. 265:1991;2667.
    • (1991) JAMA , vol.265 , pp. 2667
    • Noble, E.P.1    Blum, K.2
  • 82
    • 0027340744 scopus 로고
    • 2 receptor gene (letter)
    • 2 receptor gene (letter). JAMA. 270:1993;1547.
    • (1993) JAMA , vol.270 , pp. 1547
    • Noble, E.P.1    Blum, K.2
  • 92
    • 0030587624 scopus 로고    scopus 로고
    • 2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphism: Enhanced frequencies in psychostimulant-preferring polysubstance abusers
    • 2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphism. Enhanced frequencies in psychostimulant-preferring polysubstance abusers Biol. Psychiatry. 40:1996;776-784.
    • (1996) Biol. Psychiatry , vol.40 , pp. 776-784
    • Persico, A.M.1    Bird, G.2    Gabbay, F.H.3    Uhl, G.R.4
  • 93
    • 0344700607 scopus 로고    scopus 로고
    • 2 dopamine receptor gene in polysubstance abusers
    • K. Blum, & E.P. Noble. Boca Raton, FL: CRC Press
    • 2 dopamine receptor gene in polysubstance abusers. Blum K., Noble E.P. Handbook of psychiatric genetics. 1997;353-366 CRC Press, Boca Raton, FL.
    • (1997) Handbook of Psychiatric Genetics , pp. 353-366
    • Persico, A.M.1    Uhl, G.R.2
  • 95
    • 0025257401 scopus 로고
    • The role of inheritance in behavior
    • Plomin R. The role of inheritance in behavior. Science. 248:1990;183-186.
    • (1990) Science , vol.248 , pp. 183-186
    • Plomin, R.1
  • 98
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N., Merikangas K. The future of genetic studies of complex human diseases. Science. 273:1996;1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 99
    • 0029665177 scopus 로고    scopus 로고
    • 2 dopamine receptor polymorphism
    • 2 dopamine receptor polymorphism Brain Res. 718:1996;193-197.
    • (1996) Brain Res. , vol.718 , pp. 193-197
    • Ritchie, T.1    Noble, E.P.2
  • 100
    • 0002200725 scopus 로고
    • Alcohol disorders in the community: A report from the epidemiological catchment area
    • P.M. Rose, & J. Barrett. New York: Raven Press
    • Robins L.N., Helzer J.E., Przybeck T.R., Reiger D.A. Alcohol disorders in the community. A report from the epidemiological catchment area Rose P.M., Barrett J. Alcoholism. Origins and outcome:1988;15-29 Raven Press, New York.
    • (1988) Alcoholism: Origins and Outcome , pp. 15-29
    • Robins, L.N.1    Helzer, J.E.2    Przybeck, T.R.3    Reiger, D.A.4
  • 101
    • 0030062158 scopus 로고    scopus 로고
    • Efficiency of different viral promoters in directing gene expression in mammalian cells: Effect of 3′-untranslated sequences
    • Rotondaro L., Mele A., Rovera G. Efficiency of different viral promoters in directing gene expression in mammalian cells. Effect of 3′-untranslated sequences Gene. 168:1996;195-198.
    • (1996) Gene , vol.168 , pp. 195-198
    • Rotondaro, L.1    Mele, A.2    Rovera, G.3
  • 103
    • 0025874632 scopus 로고
    • Haplotyping of double PCR amplification of specific alleles
    • Sarkar G., Sommer S.S. Haplotyping of double PCR amplification of specific alleles. Biotechniques. 10:1991;436-440.
    • (1991) Biotechniques , vol.10 , pp. 436-440
    • Sarkar, G.1    Sommer, S.S.2
  • 105
    • 0028263741 scopus 로고
    • Association between a detection polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy
    • Schunkert H., Hense H.-W., Holmer S.R., Stender M., Perz S., Keil U., Lorell B.H., Riegger G.A. Association between a detection polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. N. Engl. J. Med. 330:1994;1634-1638.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1634-1638
    • Schunkert, H.1    Hense, H.-W.2    Holmer, S.R.3    Stender, M.4    Perz, S.5    Keil, U.6    Lorell, B.H.7    Riegger, G.A.8
  • 107
    • 0026536877 scopus 로고
    • 'Haw River syndrome' or dentato-rubo-pallido-luysian atrophy? (letter)
    • Singer C. 'Haw River syndrome' or dentato-rubo-pallido-luysian atrophy? (letter). Arch. Neurol. 49:1992;13-14.
    • (1992) Arch. Neurol. , vol.49 , pp. 13-14
    • Singer, C.1
  • 114
    • 0022979377 scopus 로고
    • Transient expression of murine interferon-alpha genes in mouse and monkey cells
    • Van Heuvel M., Bosveld I.J., Trapman J., Zwarthoff E.C. Transient expression of murine interferon-alpha genes in mouse and monkey cells. Gene. 45:1986;159-165.
    • (1986) Gene , vol.45 , pp. 159-165
    • Van Heuvel, M.1    Bosveld, I.J.2    Trapman, J.3    Zwarthoff, E.C.4


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