The regulation of D2 dopamine receptor expression

Molecular Psychiatry

Volumn 3, Issue 3, 1998, Pages 198-203

  Hitzemann, R J ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR;

CONTROLLED STUDY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; INBRED STRAIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; REVIEW; ANIMAL; ARTICLE; BRAIN LEVEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; BRAIN CHEMISTRY; GENE EXPRESSION REGULATION; HUMANS; MICE; POLYMORPHISM, GENETIC; RECEPTORS, DOPAMINE D2;

EID: 0031596425     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000388     Document Type: Review

References (67)

1. 2 receptor gene. Mol Psychiatry 1998; 3: 261-265.
2. 2 receptor availability in healthy volunteers. Mol Psychiatry 1998; 3: 256-260.
3. Noble EP, Blum K, Ritchie T, Montgomery A, Sheridan PJ. Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry 1991; 48: 648-654.
4. Blum K, Noble EP, Sheridan PJ, Montomery A, Richie T, Jagadeeswaran P et al. Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA 1990; 263: 2055-2059.
5. Parisan A, Todd RD, Devor EJ, O'Malley KL, Suarez BK, Reich T et al. Alcoholism and alleles of the human D2 dopamine receptor locus. Studies of association and linkage. Arch Gen Psychiatry 1991; 48: 655-663.
6. Comings DE, Comings BG, Muhleman D, Dietz G, Shahbahrami B, Tast D et al. The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders. JAMA 1991; 266: 1793-1800.
7. 2 dopamine receptor TaqI B1 RFLP with severe alcoholics. Alcohol 1993; 10: 59-67.
8. Blum K, Noble EP, Sheridan PJ, Finley O, Montgomery A, Ritchie T et al. Association of the A1 allele of the D2 dopamine receptor gene with severe alcoholism. Alcohol 1991; 8: 409-416.
9. 2 receptor RFLPs, haplotypes and their association with substance use in black and Caucasian research volunteers. Hum Hered 1993; 43: 209-218.
10. 2 dopamine receptor TaqI BI restriction fragment length polymorphism appears more frequently in polysubstance abusers. Arch Gen Psychiatry 1992; 49: 723-727.
11. 2 dopamine receptor gene with cocaine dependence. Drug Alcohol Depend 1993; 33: 271-285.
12. Persico AM, Bird G, Gabbay FH, Uhl GR. D2 dopamine receptor gene Taq1 A1 and B1 restriction fragment length polymorphisms: enhanced frequencies in psycho-stimulant-preferring polysubstance abusers. Biol Psychiatry 1996; 40: 776-784.
13. 2 dopamine receptor gene (DRD2) and alcoholism. JAMA 1991; 266: 1801-1807.
14. 2 receptor gene and alcoholism. JAMA 1990; 264: 3156-3160.
15. 2 receptor gene and severe alcoholism. Biol Psychiatry 1992; 31: 285-290.
16. Cook B, Wang Z, Crowe R, Hausser R, Freimer M. Alcoholism and the D2 receptor gene. Alcohol Clin Exp Res 1992; 4: 806-809.
17. Heinz A, Sander T, Harms H, Finckh U, Kuhn S, Dufeu P et al. Lack of allelic association of dopamine D1 and D2 (TaqIA) receptor gene polymorphisms with reduced dopaminergic sensitivity to alcoholism. Alcohol Clin Exp Res 1996; 20: 1109-1113.
18. Barr CL, Kidd KK. Population frequencies of the A1 allele at the dopamine D2 receptor locus. Biol Psychiatry 1993; 34: 204-209.
19. Chen WJ, Lu ML, Hsu YPP, Chen CC, Yu JM, Cheng ATA. Dopamine D2 receptor gene and alcoholism among four aboriginal groups and Han in Taiwan. Am J Med Genet 1997; 74: 129-136.
20. Koob GF. Drug of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 1992; 13: 177-184.
21. Hietala J, West C, Syvalahti E, Nagren K, Lehikoinen P, Sonninen P et al. Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence. Psychopharmacology 1994; 116: 285-290.
22. Volkow ND, Wang G-J, Fowler JS, Logan J, Hitzemann R, Ding Y-S et al. Decreases in dopamine receptors but not in dopamine transporters in alcoholics. Alcohol Clin Exp Res 1996; 20: 1594-1598.
23. 2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 1993; 14: 169-177.
24. Volkow ND, Wang G-J, Fowler JS, Logan J, Gatley SJ, Hitzemann R et al. Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 1997; 386: 830-833.
25. 2 receptor availability in opiate-dependent subjects before and after naloxone-precipitated withdrawal. Neuropsychopharmacology 1997, 16: 174-182.
26. Seeman P, Niznik HB. Dopamine receptors and transporters in Parkinson's disease and schizophrenia. FASEB J 1990; 4: 2737-2744.
27. Gejman PV, Ram A, Gelernter J, Friedman E, Cao Q, Pickar D et al. No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis. JAMA 1994; 271: 204-208.
28. 4) receptors in schizophrenia. Biol Psychiatry 1996; 40: 1209-1217.
29. 2 receptor Ser_Cys311 mutation in schizophrenia. Psychiatr Genet 1394; 4: 229-230.
30. 2 receptor gene is associated with schizophrenia. Hum Mol Genet 1997; 6: 577-582.
31. 2 receptor gene. Psychiatr Genet 1995; 5: 63-65.
32. 2 receptor genes and bipolar affective disorder. Am J Psychiatry 1992; 149: 199-201.
33. 2 receptor. Neuropsychobiology 1994; 29; 61-63.
34. 2 receptor gene in Tourette's syndrome using the haplotype relative risk method. Am J Med Genet 1994; 54: 249-252.
35. Blum K, Braverman ER, Wu S, Cull JG, Chen TJH, Gill J et al. Association of polymorphisms of dopamine D2 receptor (DRD2), and dopamine transporter (DAT(1)) genes with schizoid/avoidant behaviors (SAB). Mol Psychiatry 1997; 2: 239-246.
36. Vadasz C, Laslovszky I, De Simone PA, Fleischer A. Genetic aspects of dopamine receptor binding in the mouse and rat brain: an overview. J Neurochem 1992; 59: 793-808.
37. Pohjalainen T, Cravchik A, Gejman PV, Rinne J, Nagron K, Syvalahti E et al. Antagonist binding characteristics of the Ser(311)-JCYS variant of human dopamine D2 receptor in vivo and in vitro. Biochem Biophys Res Commun 1997; 232: 143-146.
38. Helmeste DM, Seeman P. Genetic differences in brain dopamine receptors and amphetamine responses: possible model for hyper kinetic children. Prog Clin Biol Res 1983; 135: 401-403.
39. Ciaranello RE, Boehme R. Genetic regulation of neurotransmitters enzyme and receptors: relationship to the inheritance of psychiatric disorders. Behav Genet 1982; 12: 11-35.
40. Belmaker RH, Bannet J, Brecher-Friede E, Yanai J, Ebstein RP. The effect of haloperidol feeding on dopamine receptor number in ten mouse strains. Clin Genet 1981; 19: 353-356.
41. Fink JS, Swerdloff A, Reis DJ. Genetic control of dopamine receptors in mouse caudate-nucleus: relationship on cataleptic response to neuroleptic drugs. Neurosci Lett 1982; 32: 301-306.
42. Michaluk J, Antkiewicz-Michaluk L, Rokosz-Pelc A, Sansome M, Oliverio A, Vetulani J. Dopamine receptors in the striatum and limbic system of various strains of mice: relation to differences in responses to apomorphine. Pharmacol Biochem Behav 1982; 17: 1115-1118.
43. Erwin VG, Womer DE, Campbell AD, Jones BC. Pharmacokinetics of cocaine: II. Mesocorticolimbic and striatal dopamine and cocaine receptors in C57BL and DBA mice. Pharmacogenetics 1993; 3: 189-196.
44. Kanes S, Hitzemann B, Hitzemann R. On the relationships between dopamine receptor density and haloperidol-induced catalepsy among eight inbred mouse strains. J Pharmacol Exp Ther 1993; 267: 538-547.
45. Hitzemann RJ, Hitzemann B, Dains K, Qian Y, Kanes S. Dopamine and acetylcholine cell density in the neuroleptic responsive (NR) and neuroleptic nonresponsive (NNR) lines of mice. J Pharmacol Exp Ther 1993; 266: 431-438.
46. Helmeste DM. Spontaneous and apomorphine-induced locomotor changes parallel dopamine receptor differences in two rat strains. Pharmacol Biochem Behav 1983; 19: 153-155.
47. Rosengarten H, Schweitzer JW, Friedhoff AJ. Selective dopamine D2 receptor reduction enhances a D1-mediated oral dyskinesia in rats. Life Sci 1986; 39: 29-35.
48. Kerr LM, Unis AS, Wamsley JK. Comparison of the density and distribution of brain D-1 and D-2 dopamine receptors in Buffalo vs Fischer 344 rats. Pharmacol Biochem Behav 1988; 30: 325-330.
49. 2 dopamine receptors in outbred and inbred strains of rat. Brain Res 1992; 584: 45-54.
50. Leprohon-Greenwood CE, Cinader B. Variations in age-related decline in striatal D2-dopamine receptors in a variety of mouse strains. Mech Ageing Develop 1987; 38: 199-206.
51. Greenwood CE, Cinader B. Age-related decline in striatal D2-dopamine receptors is subject to 'economic correction'. Gerontology 1991; 37: 244-252.
52. Hitzemann R, Hitzemann B, Kanes S, Dains K. Genetics and organization of the basal ganglia. Int Rev Neurobiol 1995; 38: 43-94.
53. Kanes S, Dains K, Cipp L, Galley J, Hitzemann B, Rasmussen E et al. Mapping the genes for haloperidol-induced catalepsy. J Pharmacol Exp Ther 1996; 277: 1016-1025.
54. Hitzemann RJ, Dains K, Bur-Langing CM, Zahniser NR. Selection of the haloperidol non-responsive lines of mice. Psychopharmacology 1991; 103: 244-250.
55. Hitzemann B, Dains K, Kanes S, Hitzemann R. Further studies on the relationship between dopamine cell density and haloperidolinduced catalepsy. J Pharmacol Exp Ther 1994; 271: 969-976.
56. 2 dopamine receptor distribution in the neuroleptic nonresponsive and nenroleptic responsive lines of mice: a quantitative receptor autoradiographic study. J Pharmacol Exp Ther 1992; 261: 341-348.
57. 2 mRNA levels in the neuroleptic-responsive (NR) and the neuroleptic nonresponsive (NNR) lines of mice. J Pharmacol Exp Ther 1993; 267: 1582-1590.
58. Rasmussen E, Cipp L, Patel V, Mahjubi E, Hitzemann R. Haloperidol-induced catalepsy does not map to Drd2 in a BALB/c × LP cross. Soc Neurosci 1997; 23: 722.2
59. Belknap JK. Empirical estimates of Bonferroni corrections for use in chromosome mapping studies with the BXD recombinant inbred strains. Behav Genet 1992; 22: 677-684.
60. 1B receptor is localized predominantly on axon terminals. Neuroscience 1994; 58: 167-182.
61. Darvasi A. Interval-specific congenic strains (ISCS): an experimental design for mapping a QTL into a 1-centimorgan interval. Mammalian Genome 1997; 8: 163-167.
62. Cao Q, Martinez M, Zhang J, Sanders AR, Badner JA, Cravchik A et al. Suggestive evidence for a schizophrenia susceptibility locus on chromosome 6q and a confirmation in an independent series of pedigrees. Genomics 1997; 43: 1-8.
63. Minowa T, Minowa MT, Mouradian MM. Analysis of the promoter region of the rat D2 dopamine receptor gene. Biochemistry 1992; 31: 8389-8396.
64. Valdenaire O, Vernier P, Maus M, Dumas-Milne-Edwards JB, Mallet J. Transcription of the rat dopamine-D2-receptor gene from two promoters. Eur J Biochem 1994; 220: 577-584.
65. 2 dopamine receptor mRNA level. Neurosci Lett 1990; 111: 303-308.
66. Matsunaga T, Ohara K, Natsukari N, Fujita M. Dopamine D2 receptor mRNA level in rat striatum after chronic haloperidol treatment. Neurosci Res 1991; 12: 440-445.
67. 2 dopamine receptor aging. Brain Res 1992; 575: 309-314.