Apoptosis of Burkitt's lymphoma cells induced by specific interaction of surface IgM with a self-antigen: Implications for lymphomagenesis in acquired immunodeficiency syndrome

Blood

Volumn 88, Issue 2, 1996, Pages 599-608

  Roncella, Silvio ^a   Cutrona, Giovanna ^b   Favre, Anna ^b   Ulivi, Massimo ^b   Fais, Franco ^b   Signorini, Alessandra ^b   Grossi, Carlo E ^b   Chiorazzi, Nicholas ^b   Ferrarini, Manlio ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIGEN RECOGNITION; APOPTOSIS; ARTICLE; BURKITT LYMPHOMA; CANCER RISK; CARCINOGENESIS; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029978545     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.2.599.bloodjournal882599     Document Type: Article

References (55)

1. Haluska FG, Tsujimoto Y, Croce CM: Oncogene activation by chromosome translocation in human malignancy. Annu Rev Genet 21:321, 1987
2. Klein G: Multiple phenotypic consequences of the Ig-myc translocation in B-cell derived tumors. Genes Chromosom Cancer 1:3, 1989
3. Magrath I: The pathogenesis of Burkitt's lymphoma. Adv Cancer Res 55:133, 1990
4. Shiramizu B, Barriga F, Neequayl J, Ayesha J, Dalla-Favera R, Neri A, Guttierez M, Levine P, Magrath I: Patterns of chromosomal breakpoint locations in Burkitt's lymphoma: Relevance to geography and Epstein-Barr virus association. Blood 77:1516, 1991
5. Neri A, Barriga F, Knowles DM, Magrat IT: Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt's lymphoma. Proc Natl Acad Sci USA 85:2748, 1988
6. Levine AM: Lymphoma in acquired immunodeficiency syndrome. Semin Oncol 17:104, 1990
7. Karp JE, Broder S: Acquired immunodeficiency syndrome and non-Hodgkin's lymphomas. Cancer Res 51:4743, 1991
8. Gaidano G, Dalla-Favera R: Biologic aspects of human immunodeficiency virus-related lymphoma. Curr Opin Oncol 4:900, 1992
9. Klein G, Klein E: Evolution of tumors and the impact of molecular oncology. Nature 315:190, 1985
10. Lenoir GM, Bornkamm GW: Burkitt's lymphoma, a human cancer model for the study of the multi-step development of cancer: Proposal for a new scenario. Adv Virol Oncol 7:173, 1988
11. Jain R, Roncella S, Hashimoto S, Carbone A, Francia Di Celle P, Foà R, Ferrarini M, Chiorazzi N: A potential role for antigen selection in the clonal evolution of Burkitt's lymphoma. J Immunol 153:45, 1994
12. H4-21 segments. Blood 83:2952, 1994
13. H-gene putative somatic mutation analysis. Blood 83:1067, 1994
14. H genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity. Blood 85:2176, 1995
15. Liu Y-J, Jonson GD, Gordon J, MacLennan ICM: Germinal centers in T-cell-dependent antibody responses. Immunol Today 13:17, 1992
16. Thorbecke GJ, Amin AR, Tsiagbe VK: Biology of germinal centers in lymphoid tissue. FASEB J 8:832, 1994
17. Küppers R, Zhao M, Hansmann M-L, Rajewski K: Tracing B cell development in human germinal centers by molecular analysis of single cells picked from histological sections. EMBO J 12:4955. 1993
18. Clark EA, Ledbetter JA: How B and T cells talk to each other. Nature 367:425, 1994
19. Durie FH, Foy TM, Masters SR, Laman JD, Noelle RJ: The role of CD40 in the regulation of humoral and cell-mediated immunity. Immunol Today 15:406, 1994
20. Teng NNH, Lam KS, Calvo Riera F, Kaplan HS: Construction and testing of mouse-human heteromyelomas for human monoclonal antibody production. Proc Natl Acad Sci USA 80:7308, 1983
21. Pistillo MP, Mazzoleni O, Kun L, Falco M, Tazzari PL, Ferrara GB: Production of two human hybridomas secreting antibodies to HLA-DRw11 and-Drw8+w12 specificities. Hum Immunol 31:86, 1991
22. + human chronic lymphocytic leukemia B cells. Production of IgG antibodies that exhibit diminished autoreactivity and IgG subclass skewing. Autoimmunity 19:39, 1994
23. Silberstein LE, Jefferies LC, Goldman J, Friedman D, Moore JS, Nowell PC, Roelcke D, Pruzanski W, Roudier J, Silverman GJ: Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigens. Blood 78:2372, 1991
24. Paganuzzi M, Marroni P, Pezzolo A, Gimelli G, Cavallo F, Di Pierro F, De Angelis P, Forni G, Grossi CE: Genotypic, phenotypic and biological characterization of a novel human lung adenocarcinoma cell line (LC89). Oncology 51:220, 1994
25. Roncella S, Francia Di Celle P, Cutrona G, Carbone A, Sessarego M, Landonio G, Foà R, Rowe M, Ferrarini M: Cytogenetic rearrangement of c-myc oncogene occurs prior to infection with Epstein-Barr virus in the monoclonal malignant B cells from an AIDS patient. Leuk Lymphoma 9:157, 1993
26. - B cell subsets to T cell-independent mitogens. Eur J Immunol 21:351, 1991
27. Ferrarini M, Hoffman T, Fu SM, Winchester RJ, Kunkel HG: Receptors for IgM on certain human B lymphocytes. J Immunol 119:1525, 1977
28. Roncella S, Ramarli D, Cooper MK, Forni M, Caretto P, Rowe M, Francia Di Celle P, Sessarego M, Foà R, Forni G, Burrows P, Pistoia V, Ferrarini M: Establishment of an EBV-positive lymphoblastoid cell line that grows as a lymphoma in nude mice and expresses membrane CD2 molecules. Int J Cancer 45:299, 1990
29. Cutrona G, Ulivi M, Fais F, Roncella S, Ferrarini M: Transfection of the c-myc oncogene into normal Epstein-Barr virus-harboring B cells results in new phenotypic and functional features resembling those of Burkitt's lymphoma cells and normal centroblasts. J Exp Med 181:699, 1995
30. Lane P, Brocker R, Hubele S, Padovan E, Lanzavecchia A, Gray D: Soluble CD40 ligand signal to B cells in T cell-dependent activation can replace the normal T cell-derived CD40. J Exp Med 177:1209, 1993
31. Holder MJ, Wang H, Milner AE, Casamayor M, Armitage R, Spriggs MK, Fanslow WC, MacLennan ICM, Gregory CD, Gordon J: Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bcl-2 induction. Eur J Immunol 23:2368, 1993
32. Henderson S, Rowe M, Gregory C, Croom-Carter D, Wang F, Longnecher E, Kieff E, Rickinson AB: Induction of Bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65:1107, 1991
33. Dameshek W, Schwartz RS: Leukemia and autoimmunization: Some possible relationships. Blood 14:1151, 1959
34. Dighiero G: Autoantibody activity and V gene usage by B-cell malignancies. Adv Exp Med Biol 347:125, 1994
35. Kipps TJ, Carson DA: Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases. Blood 81:2475, 1993
36. Broker BM, Klajman A, Youinou P, Jouquan J, Worman CP, Murphy J, Mackenzie L, Quartey-Papfio R, Blaschek M, Collins P, Lai S, Lydyard PM: Chronic lymphocytic leukemia cells secrete multispecific antibodies. J Autoimmunity 1:469, 1988
37. Sthoeger ZM, Wakai M, Tse DB, Vinciguerra VP, Allen SL, Budman DR, Lichtman SM, Schulman P, Weiselberg LR, Chiorazzi N: Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia. J Exp Med 169:255, 1989
38. Konrad RJ, Kricka LJ, Goodman DBP, Goldman J, Silberstein LE: Myeloma-associated paraprotein directed against the HIV-1 p24 antigen in an HIV-1-seropositive patient. N Engl J Med 328:1817, 1993
39. Heriot K, Hallquist AE, Tomar RH: Paraproteinemia in patients with acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome (LAS). Clin Chem 31:1224, 1985
40. Meeker T, Lowder J, Cleary MI, Stewart S, Warnke R, Sklar J, Levy R: Emergence of idiotype variants during treatment of B cell lymphoma with anti-idiotype antibodies. N Engl J Med 312:1658, 1985
41. Cleary ML, Galili N, Treia M, Levy R, Sklar J: Single cell origin of bigenotypic and biphenotypic B cell proliferation in human follicular lymphomas. J Exp Med 167:582, 1988
42. Friedman DF, Cho EA, Goldman J, Carmack CE, Besa EC, Hardy RR, Silberstein LE: The role of clonal selection in the pathogenesis of an autoreactive human B cell lymphoma. J Exp Med 174:525, 1991
43. Zelenetz AD, Chen T, Levy R: Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection. J Exp Med 176:1137, 1992
44. - chronic lymphocytic leukemia-producing pathologic IgM rheumatoid factor. J Immunol 144:1526, 1990
45. Davidson A, Preud'Homme J-L, Solomon A, Chang M-D Y, Beede S, Diamond B: Idiotypic analysis of myeloma proteins: AntiDNA activity of monoclonal immunoglobulins bearing an SLE idiotype is more common in IgG than IgM antibodies. J Immunol 138:1515, 1987
46. + chronic lymphocytic leukemia B cells. J Exp Med 181:1507, 1995
47. Laksy JL, Ponzio NM, Thorbecke GJ: Characterization and growth factor requirements of SJL lymphomas. I. Development of a B cell growth factor-dependent in vitro cell line. cRCS-X. J Immunol 140:679, 1988
48. + T cell clones. J Immunol 144:2550, 1990
49. Kobayashi R, Rassenti LZ, Meisenholder G, Carson DA, Kipps TJ: Autoantigen inhibits apoptosis of a human B cell leukemia that produces pathogenic rheumatoid factor. J Immunol 151:7273, 1993
50. Falk MH, Trauth BC, Debatin K-M, Klas C, Gregory CD, Rickinson AB, Calender A, Lenoir GM, Ellwart JW, Krammer PH, Bornkamm GW: Expression of the APO-1 antigen in Burkitt's lymphoma cell lines correlates with a shift towards a lymphoblastoid phenotype. Blood 79:3300, 1992
51. Krammer PH, Dhein J, Walczak H, Behrmann I, Mariani S, Matiba B, Fath M, Daniel PT, Knipping E, Westendorp MO, Stricker K, Bäumler C, Hellbardt S, Germer M, Peter ME, Debatin K-M: The role of APO-1-mediated apoptosis in the immune system. Immunol Rev 142:175, 1994
52. Banchereau J, Bazan F, Blanchard D, Briere F, Galizzi JP, van-Kooten C, LiuYJ, Rousset F, Saeland S: The CD40 antigen and its ligand. Annu Rev Immunol 12:881, 1994
53. Tiegs SL, Russell DM, Nemazee D: Receptor editing in self-reactive bone marrow B cells. J Exp Med 177:1009, 1993
54. Gay D, Saunders T, Camper S, Weigert M: Receptor editing: An approach by autoreactive B cells to escape tolerance. J Exp Med 177:999, 1993
55. Saglio SM, Borrello G., Guerrasio A, Sozzi G, Serra A, Francia Di Celle P, Foà R, Ferrarini M, Roncella S, Pignatti CB, Marradi P, Izzo P, Soler J, Pierotti M: Preferential clustering of chromosomal breakpoints in Burkitt's lymphomas and L3 type acute lymphoblastic leukemias with a t(8;14) translocation. Genes Chromosom Cancer 8:1, 1993